-
1
-
-
84897019542
-
Oxygen sensing, hypoxia-inducible factors, and disease pathophysiology
-
Semenza GL. Oxygen sensing, hypoxia-inducible factors, and disease pathophysiology. Annu Rev pathol 2013;9:47-71.
-
(2013)
Annu Rev pathol
, vol.9
, pp. 47-71
-
-
Semenza, G.L.1
-
2
-
-
0035834409
-
A conserved family of prolyl-4-hydroxylases that modify hif
-
Bruick RK, McKnight SL. A conserved family of prolyl-4-hydroxylases that modify HIF. Science 2001;294:1337-40.
-
(2001)
Science
, vol.294
, pp. 1337-1340
-
-
Bruick, R.K.1
McKnight, S.L.2
-
3
-
-
0343777395
-
Efficient translation of mouse hypoxia-inducible factor-1alpha under normoxic and hypoxic conditions
-
Gorlach A, Camenisch G, Kvietikova I, Vogt L, Wenger RH, Gassmann M. Efficient translation of mouse hypoxia-inducible factor-1alpha under normoxic and hypoxic conditions. Biochim Biophys Acta 2000; 1493:125-34.
-
(2000)
Biochim Biophys Acta
, vol.1493
, pp. 125-134
-
-
Gorlach, A.1
Camenisch, G.2
Kvietikova, I.3
Vogt, L.4
Wenger, R.H.5
Gassmann, M.6
-
5
-
-
34047215555
-
Rack1 vs. Hsp90: Competition for hif-1 alpha degradation vs. Stabilization
-
Liu YV, Semenza GL. RACK1 vs. HSP90: competition for HIF-1 alpha degradation vs. stabilization. Cell Cycle 2007;6:656-9.
-
(2007)
Cell Cycle
, vol.6
, pp. 656-659
-
-
Liu, Y.V.1
Semenza, G.L.2
-
6
-
-
0037119415
-
Hsp90 regulates a von Hippel Lindau-independent hypoxiainducible factor-1 alpha-degradative pathway
-
Isaacs JS, Jung YJ, Mimnaugh EG, Martinez A, Cuttitta F, Neckers LM. Hsp90 regulates a von Hippel Lindau-independent hypoxiainducible factor-1 alpha-degradative pathway. J Biol Chem2002;277: 29936-44.
-
(2002)
J Biol Chem
, vol.277
, pp. 29936-29944
-
-
Isaacs, J.S.1
Jung, Y.J.2
Mimnaugh, E.G.3
Martinez, A.4
Cuttitta, F.5
Neckers, L.M.6
-
7
-
-
22244458854
-
Characterization of a human rhomboid homolog, p100hrho/rhbdf1, which interacts with tgf-Alpha family ligands
-
Nakagawa T, Guichard A, Castro CP, Xiao Y, Rizen M, Zhang HZ, et al. Characterization of a human rhomboid homolog, p100hRho/RHBDF1, which interacts with TGF-Alpha family ligands. Dev Dyn 2005;233: 1315-31.
-
(2005)
Dev Dyn
, vol.233
, pp. 1315-1331
-
-
Nakagawa, T.1
Guichard, A.2
Castro, C.P.3
Xiao, Y.4
Rizen, M.5
Zhang, H.Z.6
-
8
-
-
58549108805
-
Rhomboid proteases and their biological functions
-
Freeman M. Rhomboid proteases and their biological functions. Annu Rev Genet 2008;42:191-210.
-
(2008)
Annu Rev Genet
, Issue.42
, pp. 191-210
-
-
Freeman, M.1
-
9
-
-
35948982252
-
Functional and evolutionary implications of enhanced genomic analysis of rhomboid intramembrane proteases
-
Lemberg MK, Freeman M. Functional and evolutionary implications of enhanced genomic analysis of rhomboid intramembrane proteases. Genome Res 2007;17:1634-46.
-
(2007)
Genome Res
, vol.17
, pp. 1634-1646
-
-
Lemberg, M.K.1
Freeman, M.2
-
10
-
-
79953269767
-
Rhomboid family pseudoproteases use the er quality control machinery to regulate intercellular signaling
-
Zettl M, Adrain C, Strisovsky K, Lastun V, Freeman M. Rhomboid family pseudoproteases use the ER quality control machinery to regulate intercellular signaling. Cell 2011;145:79-91.
-
(2011)
Cell
, vol.145
, pp. 79-91
-
-
Zettl, M.1
Adrain, C.2
Strisovsky, K.3
Lastun, V.4
Freeman, M.5
-
11
-
-
49849094826
-
Human rhomboid family-1 gene silencing causes apoptosis or autophagy to epithelial cancer cells and inhibits xenograft tumor growth
-
Yan Z, Zou H, Tian F, Grandis JR, Mixson AJ, Lu PY, et al. Human rhomboid family-1 gene silencing causes apoptosis or autophagy to epithelial cancer cells and inhibits xenograft tumor growth. Mol Cancer Ther 2008;7:1355-64.
-
(2008)
Mol Cancer Ther
, vol.7
, pp. 1355-1364
-
-
Yan, Z.1
Zou, H.2
Tian, F.3
Grandis, J.R.4
Mixson, A.J.5
Lu, P.Y.6
-
12
-
-
59649109249
-
Human rhomboid family-1 gene rhbdf1 participates in gpcr-mediated transactivation of egfr growth signals in head and neck squamous cancer cells
-
Zou H, Thomas SM, Yan ZW, Grandis JR, Vogt A, Li LY. Human rhomboid family-1 gene RHBDF1 participates in GPCR-mediated transactivation of EGFR growth signals in head and neck squamous cancer cells. FASEB J 2009;23:425-32.
-
(2009)
FASEB J
, vol.23
, pp. 425-432
-
-
Zou, H.1
Thomas, S.M.2
Yan, Z.W.3
Grandis, J.R.4
Vogt, A.5
Li, L.Y.6
-
13
-
-
33845298019
-
Receptor for activated c kinase 1 (rack1) and src regulate the tyrosine phosphorylation and function of the androgen receptor
-
Kraus S, Gioeli D, Vomastek T, Gordon V, Weber MJ. Receptor for activated C kinase 1 (RACK1) and Src regulate the tyrosine phosphorylation and function of the androgen receptor. Cancer Res 2006; 66:11047-54.
-
(2006)
Cancer Res
, vol.66
, pp. 11047-11054
-
-
Kraus, S.1
Gioeli, D.2
Vomastek, T.3
Gordon, V.4
Weber, M.J.5
-
15
-
-
0142211270
-
A new histological grading system to assess response of breast cancers to primary chemotherapy: Prognostic significance and survival
-
Ogston KN, Miller ID, Payne S, Hutcheon AW, Sarkar TK, Smith I, et al. A new histological grading system to assess response of breast cancers to primary chemotherapy: prognostic significance and survival. Breast 2003;12:320-7.
-
(2003)
Breast
, vol.12
, pp. 320-327
-
-
Ogston, K.N.1
Miller, I.D.2
Payne, S.3
Hutcheon, A.W.4
Sarkar, T.K.5
Smith, I.6
-
16
-
-
0344915156
-
Expression of fas (cd95/apo-1) and fas ligand in lung cancer, its prognostic and predictive relevance
-
Koomagi R, Volm M. Expression of Fas (CD95/APO-1) and Fas ligand in lung cancer, its prognostic and predictive relevance. Int J Cancer 1999;84:239-43.
-
(1999)
Int J Cancer
, vol.84
, pp. 239-243
-
-
Koomagi, R.1
Volm, M.2
-
17
-
-
84872346471
-
Vegf, hif-1alpha expression and mvd as an angiogenic network in familial breast cancer
-
Saponaro C, Malfettone A, Ranieri G, Danza K, Simone G, Paradiso A, et al. VEGF, HIF-1alpha expression and MVD as an angiogenic network in familial breast cancer. PloS ONE 2013;8: e53070.
-
(2013)
PloS ONE
, vol.8
-
-
Saponaro, C.1
Malfettone, A.2
Ranieri, G.3
Danza, K.4
Simone, G.5
Paradiso, A.6
-
18
-
-
67749102204
-
Characteristics and prognosis for molecular breast cancer subtypes in chinese women
-
Zhao J, Liu H, Wang M, Gu L, Guo X, Gu F, et al. Characteristics and prognosis for molecular breast cancer subtypes in Chinese women. J Surg Oncol 2009;100:89-94.
-
(2009)
J Surg Oncol
, vol.100
, pp. 89-94
-
-
Zhao, J.1
Liu, H.2
Wang, M.3
Gu, L.4
Guo, X.5
Gu, F.6
-
19
-
-
78649327037
-
Expression of hab18g is associated with tumor progression and prognosis of breast carcinoma
-
Liu F, Cui L, Zhang Y, Chen L, Wang Y, Fan Y, et al. Expression of HAb18G is associated with tumor progression and prognosis of breast carcinoma. Breast Cancer Res Treat 2010;124:677-88.
-
(2010)
Breast Cancer Res Treat
, vol.124
, pp. 677-688
-
-
Liu, F.1
Cui, L.2
Zhang, Y.3
Chen, L.4
Wang, Y.5
Fan, Y.6
-
20
-
-
0026485002
-
Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis
-
Shweiki D, Itin A, Soffer D, Keshet E. Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis. Nature 1992;359:843-5.
-
(1992)
Nature
, vol.359
, pp. 843-845
-
-
Shweiki, D.1
Itin, A.2
Soffer, D.3
Keshet, E.4
-
21
-
-
54549113030
-
The von Hippel-Lindau tumour suppressor protein: O2 sensing and cancer
-
Kaelin WG Jr. The von Hippel-Lindau tumour suppressor protein: O2 sensing and cancer. Nat Rev Cancer 2008;8:865-73.
-
(2008)
Nat Rev Cancer
, vol.8
, pp. 865-873
-
-
Kaelin Jr., W.G.1
-
22
-
-
37549028456
-
Calcineurin promotes hypoxia-inducible factor 1alpha expression by dephosphorylating rack1 and blocking rack1 dimerization
-
Liu YV, Hubbi ME, Pan F, McDonald KR, Mansharamani M, Cole RN, et al. Calcineurin promotes hypoxia-inducible factor 1alpha expression by dephosphorylating RACK1 and blocking RACK1 dimerization. J Biol Chem 2007;282:37064-73.
-
(2007)
J Biol Chem
, vol.282
, pp. 37064-37073
-
-
Liu, Y.V.1
Hubbi, M.E.2
Pan, F.3
McDonald, K.R.4
Mansharamani, M.5
Cole, R.N.6
-
23
-
-
66049135249
-
Generation of induced pluripotent stem cells using recombinant proteins
-
Zhou H, Wu S, Joo JY, Zhu S, Han DW, Lin T, et al. Generation of induced pluripotent stem cells using recombinant proteins. Cell Stem Cell 2009;4:381-4.
-
(2009)
Cell Stem Cell
, vol.4
, pp. 381-384
-
-
Zhou, H.1
Wu, S.2
Joo, J.Y.3
Zhu, S.4
Han, D.W.5
Lin, T.6
-
24
-
-
34248195608
-
Highhsp90 expression is associated with decreased survival in breast cancer
-
Pick E, Kluger Y, Giltnane JM, Moeder C, Camp RL, Rimm DL, et al. HighHSP90 expression is associated with decreased survival in breast cancer. Cancer Res 2007;67:2932-7.
-
(2007)
Cancer Res
, vol.67
, pp. 2932-2937
-
-
Pick, E.1
Kluger, Y.2
Giltnane, J.M.3
Moeder, C.4
Camp, R.L.5
Rimm, D.L.6
-
25
-
-
77955484545
-
Rack1: A superior independent predictor for poor clinical outcome in breast cancer
-
Cao XX, Xu JD, Liu XL, Xu JW, Wang WJ, Li QQ, et al. RACK1: A superior independent predictor for poor clinical outcome in breast cancer. Int J Cancer 2009;127:1172-9.
-
(2009)
Int J Cancer
, vol.127
, pp. 1172-1179
-
-
Cao, X.X.1
Xu, J.D.2
Liu, X.L.3
Xu, J.W.4
Wang, W.J.5
Li, Q.Q.6
-
26
-
-
33749556704
-
Chronic hypoxia promotes hypoxia-inducible factor-1alpha-dependent resistance to etoposide and vincristine in neuroblastoma cells
-
Hussein D, Estlin EJ, Dive C, Makin GW. Chronic hypoxia promotes hypoxia-inducible factor-1alpha-dependent resistance to etoposide and vincristine in neuroblastoma cells. Mol Cancer Ther 2006;5: 2241-50.
-
(2006)
Mol Cancer Ther
, vol.5
, pp. 2241-2250
-
-
Hussein, D.1
Estlin, E.J.2
Dive, C.3
Makin, G.W.4
-
27
-
-
0035378480
-
Up-regulation of apoptosis inhibitory protein iap-2 by hypoxia. Hif-1-independent mechanisms
-
Dong Z, Venkatachalam MA, Wang J, Patel Y, Saikumar P, Semenza GL, et al. Up-regulation of apoptosis inhibitory protein IAP-2 by hypoxia. Hif-1-independent mechanisms. J Biol Chem 2001;276: 18702-9.
-
(2001)
J Biol Chem
, vol.276
, pp. 18702-18709
-
-
Dong, Z.1
Venkatachalam, M.A.2
Wang, J.3
Patel, Y.4
Saikumar, P.5
Semenza, G.L.6
-
28
-
-
2942700177
-
Inactive enzyme-homologues find new function in regulatory processes
-
Pils B, Schultz J. Inactive enzyme-homologues find new function in regulatory processes. J Mol Biol 2004;340:399-404.
-
(2004)
J Mol Biol
, vol.340
, pp. 399-404
-
-
Pils, B.1
Schultz, J.2
|