-
1
-
-
0024955886
-
Approaching the asymptote? Evolution and revolution in immunology
-
Janeway, Jr. C. A. Approaching the asymptote? Evolution and revolution in immunology. Cold Spring Harb. Symp. Quant. Biol. 54, 1-13 (1989).
-
(1989)
Cold Spring Harb. Symp. Quant. Biol.
, vol.54
, pp. 1-13
-
-
Janeway, C.A.1
-
2
-
-
79956300649
-
Toll-like receptors and their crosstalk with other innate receptors in infection and immunity
-
Kawai, T. & Akira, S. Toll-like receptors and their crosstalk with other innate receptors in infection and immunity. Immunity 34, 637-650 (2011).
-
(2011)
Immunity
, vol.34
, pp. 637-650
-
-
Kawai, T.1
Akira, S.2
-
3
-
-
39149107423
-
MDA5/RIG-I and virus recognition
-
Takeuchi, O. & Akira, S. MDA5/RIG-I and virus recognition. Curr. Opin. Immunol. 20, 17-22 (2008).
-
(2008)
Curr. Opin. Immunol.
, vol.20
, pp. 17-22
-
-
Takeuchi, O.1
Akira, S.2
-
4
-
-
84921047960
-
Viral RNA detection by RIG-I-like receptors
-
Yoneyama, M., Onomoto, K., Jogi, M., Akaboshi, T. & Fujita, T. Viral RNA detection by RIG-I-like receptors. Curr. Opin. Immunol. 32, 48-53 (2015).
-
(2015)
Curr. Opin. Immunol.
, vol.32
, pp. 48-53
-
-
Yoneyama, M.1
Onomoto, K.2
Jogi, M.3
Akaboshi, T.4
Fujita, T.5
-
5
-
-
3242813113
-
The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses
-
Yoneyama, M. et al. The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses. Nat. Immunol. 5, 730-737 (2004).
-
(2004)
Nat. Immunol.
, vol.5
, pp. 730-737
-
-
Yoneyama, M.1
-
6
-
-
34247341367
-
TRIM25 RING-finger E3 ubiquitin ligase is essential for RIG-I-mediated antiviral activity
-
Gack, M. U. et al. TRIM25 RING-finger E3 ubiquitin ligase is essential for RIG-I-mediated antiviral activity. Nature 446, 916-920 (2007).
-
(2007)
Nature
, vol.446
, pp. 916-920
-
-
Gack, M.U.1
-
7
-
-
24144461689
-
Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3
-
Seth, R. B., Sun, L., Ea, C. K. & Chen, Z. J. Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3. Cell 122, 669-682 (2005).
-
(2005)
Cell
, vol.122
, pp. 669-682
-
-
Seth, R.B.1
Sun, L.2
Ea, C.K.3
Chen, Z.J.4
-
8
-
-
27144440476
-
Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus
-
Meylan, E. et al. Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus. Nature 437, 1167-1172 (2005).
-
(2005)
Nature
, vol.437
, pp. 1167-1172
-
-
Meylan, E.1
-
9
-
-
24944538819
-
VISA is an adapter protein required for virus-triggered IFN-beta signaling
-
Xu, L. G. et al. VISA is an adapter protein required for virus-triggered IFN-beta signaling. Mol. Cell 19, 727-740 (2005).
-
(2005)
Mol. Cell
, vol.19
, pp. 727-740
-
-
Xu, L.G.1
-
10
-
-
27144440523
-
IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type i interferon induction
-
Kawai, T. et al. IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction. Nat. Immunol. 6, 981-988 (2005).
-
(2005)
Nat. Immunol.
, vol.6
, pp. 981-988
-
-
Kawai, T.1
-
11
-
-
59449091450
-
Riplet/RNF135, a RING finger protein, ubiquitinates RIG-I to promote interferon-beta induction during the early phase of viral infection
-
Oshiumi, H., Matsumoto, M., Hatakeyama, S. & Seya, T. Riplet/RNF135, a RING finger protein, ubiquitinates RIG-I to promote interferon-beta induction during the early phase of viral infection. J. Biol. Chem. 284, 807-817 (2009).
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 807-817
-
-
Oshiumi, H.1
Matsumoto, M.2
Hatakeyama, S.3
Seya, T.4
-
12
-
-
34250632829
-
Negative regulation of the RIG-I signaling by the ubiquitin ligase RNF125
-
Arimoto, K. et al. Negative regulation of the RIG-I signaling by the ubiquitin ligase RNF125. Proc. Natl Acad. Sci. USA 104, 7500-7505 (2007).
-
(2007)
Proc. Natl Acad. Sci. USA
, vol.104
, pp. 7500-7505
-
-
Arimoto, K.1
-
13
-
-
51049106824
-
The tumour suppressor CYLD is a negative regulator of RIG-I-mediated antiviral response
-
Friedman, C. S. et al. The tumour suppressor CYLD is a negative regulator of RIG-I-mediated antiviral response. EMBO Rep. 9, 930-936 (2008).
-
(2008)
EMBO Rep.
, vol.9
, pp. 930-936
-
-
Friedman, C.S.1
-
14
-
-
84893721948
-
USP21 negatively regulates antiviral response by acting as a RIG-I deubiquitinase
-
Fan, Y. et al. USP21 negatively regulates antiviral response by acting as a RIG-I deubiquitinase. J. Exp. Med. 211, 313-328 (2014).
-
(2014)
J. Exp. Med.
, vol.211
, pp. 313-328
-
-
Fan, Y.1
-
15
-
-
84875789033
-
USP4 positively regulates RIG-I-mediated antiviral response through deubiquitination and stabilization of RIG-I
-
Wang, L. et al. USP4 positively regulates RIG-I-mediated antiviral response through deubiquitination and stabilization of RIG-I. J. Virol. 87, 4507-4515 (2013).
-
(2013)
J. Virol.
, vol.87
, pp. 4507-4515
-
-
Wang, L.1
-
16
-
-
84861181618
-
The mitochondrial targeting chaperone 14-3-3e regulates a RIG-I translocon that mediates membrane association and innate antiviral immunity
-
Liu, H. M. et al. The mitochondrial targeting chaperone 14-3-3e regulates a RIG-I translocon that mediates membrane association and innate antiviral immunity. Cell Host. Microbe. 11, 528-537 (2012).
-
(2012)
Cell Host. Microbe.
, vol.11
, pp. 528-537
-
-
Liu, H.M.1
-
17
-
-
16244380777
-
Syndecans: New kids on the signaling block
-
Tkachenko, E., Rhodes, J. M. & Simons, M. Syndecans: new kids on the signaling block. Circ. Res. 96, 488-500 (2005).
-
(2005)
Circ. Res.
, vol.96
, pp. 488-500
-
-
Tkachenko, E.1
Rhodes, J.M.2
Simons, M.3
-
18
-
-
69949118870
-
Syndecan-4 regulates ADAMTS-5 activation and cartilage breakdown in osteoarthritis
-
Echtermeyer, F. et al. Syndecan-4 regulates ADAMTS-5 activation and cartilage breakdown in osteoarthritis. Nat. Med. 15, 1072-1076 (2009).
-
(2009)
Nat. Med.
, vol.15
, pp. 1072-1076
-
-
Echtermeyer, F.1
-
19
-
-
0032575578
-
Heparan sulfate proteoglycans as adhesive and anti-invasive molecules. Syndecans and glypican have distinct functions
-
Liu, W. et al. Heparan sulfate proteoglycans as adhesive and anti-invasive molecules. Syndecans and glypican have distinct functions. J. Biol. Chem. 273, 22825-22832 (1998).
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 22825-22832
-
-
Liu, W.1
-
20
-
-
0033869852
-
Synectin syndecan-4 cytoplasmic domain binding PDZ protein, inhibits cell migration
-
Gao, Y., Li, M., Chen, W. & Simons, M. Synectin, syndecan-4 cytoplasmic domain binding PDZ protein, inhibits cell migration. J. Cell Physiol. 184, 373-379 (2000).
-
(2000)
J. Cell Physiol.
, vol.184
, pp. 373-379
-
-
Gao, Y.1
Li, M.2
Chen, W.3
Simons, M.4
-
21
-
-
84945186042
-
Critical role for syndecan-4 in dendritic cell migration during development of allergic airway inflammation
-
Polte, T. et al. Critical role for syndecan-4 in dendritic cell migration during development of allergic airway inflammation. Nat. Commun. 6, 7554 (2015).
-
(2015)
Nat. Commun.
, vol.6
, pp. 7554
-
-
Polte, T.1
-
22
-
-
84940118564
-
Syndecan 4 regulation of the development of autoimmune arthritis in mice by modulating B cell migration and germinal center formation
-
Endo, T. et al. Syndecan 4 regulation of the development of autoimmune arthritis in mice by modulating B cell migration and germinal center formation. Arthritis Rheumatol. 67, 2512-2522 (2015).
-
(2015)
Arthritis Rheumatol.
, vol.67
, pp. 2512-2522
-
-
Endo, T.1
-
23
-
-
63449129028
-
Syndecan-1 regulates alphavbeta3 and alphavbeta5 integrin activation during angiogenesis and is blocked by synstatin, a novel peptide inhibitor
-
Beauvais, D. M., Ell, B. J., McWhorter, A. R. & Rapraeger, A. C. Syndecan-1 regulates alphavbeta3 and alphavbeta5 integrin activation during angiogenesis and is blocked by synstatin, a novel peptide inhibitor. J. Exp. Med. 206, 691-705 (2009).
-
(2009)
J. Exp. Med.
, vol.206
, pp. 691-705
-
-
Beauvais, D.M.1
Ell, B.J.2
McWhorter, A.R.3
Rapraeger, A.C.4
-
24
-
-
0037515626
-
Direct binding of syndecan-4 cytoplasmic domain to the catalytic domain of protein kinase C alpha (PKC alpha) increases focal adhesion localization of PKC alpha
-
Lim, S. T., Longley, R. L., Couchman, J. R. & Woods, A. Direct binding of syndecan-4 cytoplasmic domain to the catalytic domain of protein kinase C alpha (PKC alpha) increases focal adhesion localization of PKC alpha. J. Biol. Chem. 278, 13795-13802 (2003).
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 13795-13802
-
-
Lim, S.T.1
Longley, R.L.2
Couchman, J.R.3
Woods, A.4
-
25
-
-
84877131728
-
The syndecan-4/protein kinase Calpha pathway mediates prostaglandin E2-induced extracellular regulated kinase (ERK) activation in endothelial cells and angiogenesis in vivo
-
Corti, F., Finetti, F., Ziche, M. & Simons, M. The syndecan-4/protein kinase Calpha pathway mediates prostaglandin E2-induced extracellular regulated kinase (ERK) activation in endothelial cells and angiogenesis in vivo. J. Biol. Chem. 288, 12712-12721 (2013).
-
(2013)
J. Biol. Chem.
, vol.288
, pp. 12712-12721
-
-
Corti, F.1
Finetti, F.2
Ziche, M.3
Simons, M.4
-
26
-
-
84878524570
-
Syndecan-1 serves as the major receptor for attachment of hepatitis C virus to the surfaces of hepatocytes
-
Shi, Q., Jiang, J. & Luo, G. Syndecan-1 serves as the major receptor for attachment of hepatitis C virus to the surfaces of hepatocytes. J. Virol. 87, 6866-6875 (2013).
-
(2013)
J. Virol.
, vol.87
, pp. 6866-6875
-
-
Shi, Q.1
Jiang, J.2
Luo, G.3
-
27
-
-
84899698156
-
Syndecan 4 is involved in mediating HCV entry through interaction with lipoviral particleassociated apolipoprotein e
-
Lefevre, M., Felmlee, D. J., Parnot, M., Baumert, T. F. & Schuster, C. Syndecan 4 is involved in mediating HCV entry through interaction with lipoviral particleassociated apolipoprotein E. PLoS ONE 9, e95550 (2014).
-
(2014)
PLoS ONE
, vol.9
, pp. e95550
-
-
Lefevre, M.1
Felmlee, D.J.2
Parnot, M.3
Baumert, T.F.4
Schuster, C.5
-
28
-
-
0032475975
-
Phosphorylation of the cytoplasmic tail of syndecan-4 regulates activation of protein kinase Calpha
-
Horowitz, A. & Simons, M. Phosphorylation of the cytoplasmic tail of syndecan-4 regulates activation of protein kinase Calpha. J. Biol. Chem. 273, 25548-25551 (1998).
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 25548-25551
-
-
Horowitz, A.1
Simons, M.2
-
29
-
-
0030889054
-
Syndecan-4 proteoglycan regulates the distribution and activity of protein kinase C
-
Oh, E. S., Woods, A. & Couchman, J. R. Syndecan-4 proteoglycan regulates the distribution and activity of protein kinase C. J. Biol. Chem. 272, 8133-8136 (1997).
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 8133-8136
-
-
Oh, E.S.1
Woods, A.2
Couchman, J.R.3
-
30
-
-
77950343791
-
Pattern recognition receptors and inflammation
-
Takeuchi, O. & Akira, S. Pattern recognition receptors and inflammation. Cell 140, 805-820 (2010).
-
(2010)
Cell
, vol.140
, pp. 805-820
-
-
Takeuchi, O.1
Akira, S.2
-
31
-
-
84879916945
-
Molecular mechanisms of syndecan-4 upregulation by TNFalpha in the endothelium-like EAhy926 cells
-
Okuyama, E. et al. Molecular mechanisms of syndecan-4 upregulation by TNFalpha in the endothelium-like EAhy926 cells. J. Biochem. 154, 41-50 (2013).
-
(2013)
J. Biochem.
, vol.154
, pp. 41-50
-
-
Okuyama, E.1
-
32
-
-
84873729095
-
Multiplex genome engineering using CRISPR/Cas systems
-
Cong, L. et al. Multiplex genome engineering using CRISPR/Cas systems. Science 339, 819-823 (2013).
-
(2013)
Science
, vol.339
, pp. 819-823
-
-
Cong, L.1
-
33
-
-
84873734105
-
RNA-guided human genome engineering via Cas9
-
Mali, P. et al. RNA-guided human genome engineering via Cas9. Science 339, 823-826 (2013).
-
(2013)
Science
, vol.339
, pp. 823-826
-
-
Mali, P.1
-
34
-
-
33644850482
-
Negative regulation of the retinoic acid-inducible gene I-induced antiviral state by the ubiquitin-editing protein A20
-
Lin, R. et al. Negative regulation of the retinoic acid-inducible gene I-induced antiviral state by the ubiquitin-editing protein A20. J. Biol. Chem. 281, 2095-2103 (2006).
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 2095-2103
-
-
Lin, R.1
-
35
-
-
84864554763
-
Syndecan-4 regulates early neutrophil migration and pulmonary inflammation in response to lipopolysaccharide
-
Tanino, Y. et al. Syndecan-4 regulates early neutrophil migration and pulmonary inflammation in response to lipopolysaccharide. Am. J. Respir. Cell Mol. Biol. 47, 196-202 (2012).
-
(2012)
Am. J. Respir. Cell Mol. Biol.
, vol.47
, pp. 196-202
-
-
Tanino, Y.1
-
36
-
-
84863681065
-
Syndecan-4 and fibronectin in osteosarcoma
-
Na, K. Y., Bacchini, P., Bertoni, F., Kim, Y. W. & Park, Y. K. Syndecan-4 and fibronectin in osteosarcoma. Pathology 44, 325-330 (2012).
-
(2012)
Pathology
, vol.44
, pp. 325-330
-
-
Na, K.Y.1
Bacchini, P.2
Bertoni, F.3
Kim, Y.W.4
Park, Y.K.5
-
37
-
-
84926450646
-
PPM1A regulates antiviral signaling by antagonizing TBK1-mediated STING phosphorylation and aggregation
-
Li, Z. et al. PPM1A regulates antiviral signaling by antagonizing TBK1-mediated STING phosphorylation and aggregation. PLoS Pathog. 11, e1004783 (2015).
-
(2015)
PLoS Pathog.
, vol.11
, pp. e1004783
-
-
Li, Z.1
-
38
-
-
84872040983
-
COX5B regulates MAVS-mediated antiviral signaling through interaction with ATG5 and repressing ROS production
-
Zhao, Y. et al. COX5B regulates MAVS-mediated antiviral signaling through interaction with ATG5 and repressing ROS production. PLoS Pathog. 8, e1003086 (2012).
-
(2012)
PLoS Pathog.
, vol.8
, pp. e1003086
-
-
Zhao, Y.1
-
39
-
-
53349168904
-
The adaptor protein MITA links virus-sensing receptors to IRF3 transcription factor activation
-
Zhong, B. et al. The adaptor protein MITA links virus-sensing receptors to IRF3 transcription factor activation. Immunity 29, 538-550 (2008).
-
(2008)
Immunity
, vol.29
, pp. 538-550
-
-
Zhong, B.1
|