Augmented noncanonical BMP type II receptor signaling mediates the synaptic abnormality of fragile X syndrome

Science Signaling

Volumn 9, Issue 431, 2016, Pages

  Kashima, Risa ^a   Roy, Sougata ^a   Ascano, Manuel ^b   Martinez Cerdeno, Veronica ^c,d   Ariza Torres, Jeanelle ^c   Kim, Sunghwan ^a   Louie, Justin ^a   Lu, Yao ^a   Leyton, Patricio ^e   Bloch, Kenneth D ^e   Kornberg, Thomas B ^a   Hagerman, Paul J ^f   Hagerman, Randi ^d   Lagna, Giorgio ^a   Hata, Akiko ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e MASSACHUSETTS GENERAL HOSPITAL   (United States)

^f UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

6 [4 (1 PIPERAZINYL)PHENYL] 3 (4 QUINOLINYL)PYRAZOLO[1,5 A]PYRIMIDINE; BONE MORPHOGENETIC PROTEIN RECEPTOR 2; LIM KINASE 1; MESSENGER RNA; BMPR2 PROTEIN, HUMAN; BMPR2 PROTEIN, MOUSE; CFL1 PROTEIN, MOUSE; COFILIN 1; LIM KINASE; LIMK1 PROTEIN, HUMAN; LIMK1 PROTEIN, MOUSE; SMALL INTERFERING RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTISM; BRAIN REGION; CONTROLLED STUDY; DROSOPHILA; EMBRYO; ENZYME ACTIVITY; FEMALE; FRAGILE X SYNDROME; HETEROZYGOSITY; HUMAN; HUMAN TISSUE; MALE; MOUSE; NERVE FIBER GROWTH; NONHUMAN; PREFRONTAL CORTEX; PRIORITY JOURNAL; PROTEIN DEPLETION; SIGNAL TRANSDUCTION; SYNAPSE; ANIMAL; BRAIN; CROSS BREEDING; DROSOPHILA MELANOGASTER; GENE EXPRESSION REGULATION; GENETICS; HEK293 CELL LINE; HETEROZYGOTE; KNOCKOUT MOUSE; METABOLISM; NERVE CELL; NEURITE; PHOSPHORYLATION; PLASMID; PROTEIN DOMAIN;

ANIMALS; AUTISTIC DISORDER; BONE MORPHOGENETIC PROTEIN RECEPTORS, TYPE II; BRAIN; COFILIN 1; CROSSES, GENETIC; DROSOPHILA MELANOGASTER; FRAGILE X SYNDROME; GENE EXPRESSION REGULATION; HEK293 CELLS; HETEROZYGOTE; HUMANS; LIM KINASES; MICE; MICE, KNOCKOUT; NEURITES; NEURONS; PHOSPHORYLATION; PLASMIDS; PREFRONTAL CORTEX; PROTEIN DOMAINS; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION;

EID: 84973512776     PISSN: 19450877     EISSN: 19379145     Source Type: Journal    
DOI: 10.1126/scisignal.aaf6060     Document Type: Article

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