메뉴 건너뛰기




Volumn 6, Issue 9, 1997, Pages 1465-1472

The fragile X mental retardation protein is associated with poly(A)+ mRNA in actively translating polyribosomes

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; POLYADENYLATED RNA; RIBONUCLEOPROTEIN; RNA BINDING PROTEIN;

EID: 0030760613     PISSN: 09646906     EISSN: None     Source Type: Journal    
DOI: 10.1093/hmg/6.9.1465     Document Type: Article
Times cited : (211)

References (38)
  • 1
    • 0001475826 scopus 로고    scopus 로고
    • Recognition of the Fragile X or Martin-Bell syndrome
    • Hagerman, R.J. and Cronister, A. (eds). The Johns Hopkins University Press, Baltimore, MD
    • Sherman, S. (1996) Recognition of the Fragile X or Martin-Bell syndrome. In Hagerman, R.J. and Cronister, A. (eds). Fragile X Syndrome: Diagnosis, Treatment and Research. The Johns Hopkins University Press, Baltimore, MD, pp. 165-192.
    • (1996) Fragile X Syndrome: Diagnosis, Treatment and Research , pp. 165-192
    • Sherman, S.1
  • 3
    • 0028904864 scopus 로고
    • Triplet repeat expansion mutations: The example of fragile X syndrome
    • Warren, S.T. and Ashley, C.T. (1995) Triplet repeat expansion mutations: the example of fragile X syndrome. Annu. Rev. Neurosci., 18, 77-99.
    • (1995) Annu. Rev. Neurosci. , vol.18 , pp. 77-99
    • Warren, S.T.1    Ashley, C.T.2
  • 4
    • 0027377580 scopus 로고
    • FMR-1 protein: Conserved RNP family domains and selective RNA binding
    • Ashley, C.T. Jr, Wilkinson, K.D., Reines, D. and Warren, S.T. (1993) FMR-1 protein: conserved RNP family domains and selective RNA binding. Science, 262, 563-566.
    • (1993) Science , vol.262 , pp. 563-566
    • Ashley Jr., C.T.1    Wilkinson, K.D.2    Reines, D.3    Warren, S.T.4
  • 5
    • 0027327486 scopus 로고
    • The protein product of the fragile X gene, FMRI, has characteristics of an RNA-binding protein
    • Siomi, H., Siomi, M.C., Nussbaum, R.L. and Dreyfuss,G.(1993) The protein product of the fragile X gene, FMRI, has characteristics of an RNA-binding protein. Cell, 74, 291-298.
    • (1993) Cell , vol.74 , pp. 291-298
    • Siomi, H.1    Siomi, M.C.2    Nussbaum, R.L.3    Dreyfuss, G.4
  • 6
    • 0027176361 scopus 로고
    • The FMR-1 protein is cytoplasmic, most abundant in neurons and appears normal in carriers of a fragile X premutation
    • Devys, D., Lutz, Y., Rouyer, N., Bellocq, J.-P. and Mandel, J.-L. (1993) The FMR-1 protein is cytoplasmic, most abundant in neurons and appears normal in carriers of a fragile X premutation. Nature Genet., 4, 335-340.
    • (1993) Nature Genet. , vol.4 , pp. 335-340
    • Devys, D.1    Lutz, Y.2    Rouyer, N.3    Bellocq, J.-P.4    Mandel, J.-L.5
  • 8
    • 0029816723 scopus 로고    scopus 로고
    • The fragile X mental retardation protein is a ribonucleoprotein containing both nuclear localization and nuclear export signals
    • Eberhart, D.E, Malter, H.E, Feng, Y. and Warren, S.T, (1996) The fragile X mental retardation protein is a ribonucleoprotein containing both nuclear localization and nuclear export signals. Hum. Mol. Genet., 5, 1083-1091
    • (1996) Hum. Mol. Genet. , vol.5 , pp. 1083-1091
    • Eberhart, D.E.1    Malter, H.E.2    Feng, Y.3    Warren, S.T.4
  • 9
    • 0030059545 scopus 로고    scopus 로고
    • The fragile X mental retardation protein is associated with ribosomes
    • Khandjian, E.W., Corbin, F., Woerly, S. and Rousseau, F. (1996) The fragile X mental retardation protein is associated with ribosomes. Nature Genet., 12 , 91-93.
    • (1996) Nature Genet. , vol.12 , pp. 91-93
    • Khandjian, E.W.1    Corbin, F.2    Woerly, S.3    Rousseau, F.4
  • 10
    • 0029972935 scopus 로고    scopus 로고
    • Specific sequences in the fragile X syndrome protein FMR1 and the FXR2 proteins mediate their binding to 60S ribosomal subunits and the interactions among them
    • Siomi, M.C., Zhang, Y., Siomi, H. and Dreyfuss, G. (1996) Specific sequences in the fragile X syndrome protein FMR1 and the FXR2 proteins mediate their binding to 60S ribosomal subunits and the interactions among them. Mol. Cell. Biol., 16, 3825-3832.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 3825-3832
    • Siomi, M.C.1    Zhang, Y.2    Siomi, H.3    Dreyfuss, G.4
  • 12
    • 0029818460 scopus 로고    scopus 로고
    • A nuclear role for the fragile X mental retardation protein
    • Fridell, R.A., Benson, R.E., Hua, J., Bogerd, H.P. and Cullen, B.R. (1996) A nuclear role for the fragile X mental retardation protein. EMBO J., 15, 5408-5414.
    • (1996) EMBO J. , vol.15 , pp. 5408-5414
    • Fridell, R.A.1    Benson, R.E.2    Hua, J.3    Bogerd, H.P.4    Cullen, B.R.5
  • 13
    • 0030051618 scopus 로고    scopus 로고
    • Alternative splicing of exon 14 determines nuclear or cytoplasmic localisation of fmrl protein isoforms
    • Sittler, A., Devys, D., Weber, C. and Mandel, J.-L. (1996) Alternative splicing of exon 14 determines nuclear or cytoplasmic localisation of fmrl protein isoforms. Hum. Mol. Genet., 5, 95-102.
    • (1996) Hum. Mol. Genet. , vol.5 , pp. 95-102
    • Sittler, A.1    Devys, D.2    Weber, C.3    Mandel, J.-L.4
  • 14
    • 0031046778 scopus 로고    scopus 로고
    • Fragile X mental retardation protein: Nucleocytoplasmic shuttling and association with somatodendritic ribosomes
    • Feng, Y., Gutekunst, C-A., Eberhart, D.E., Yi, H., Warren, S.T. and Hersch, S.M. (1997) Fragile X mental retardation protein: nucleocytoplasmic shuttling and association with somatodendritic ribosomes. J. Neurosci., 17, 1539-1547.
    • (1997) J. Neurosci. , vol.17 , pp. 1539-1547
    • Feng, Y.1    Gutekunst, C.-A.2    Eberhart, D.E.3    Yi, H.4    Warren, S.T.5    Hersch, S.M.6
  • 15
    • 0028971722 scopus 로고
    • The fragile X mental retardation syndrome protein interacts with novel homologs FXR1 and FXR2
    • Zhang, Y., O'Connor, J.P., Siomi, M.C., Srinivasan, S., Dutra, A., Nussbaum, R.L. and Dreyfuss, G. (1995) The fragile X mental retardation syndrome protein interacts with novel homologs FXR1 and FXR2. EMBO J., 14, 5358-5366.
    • (1995) EMBO J. , vol.14 , pp. 5358-5366
    • Zhang, Y.1    O'Connor, J.P.2    Siomi, M.C.3    Srinivasan, S.4    Dutra, A.5    Nussbaum, R.L.6    Dreyfuss, G.7
  • 17
    • 0028880051 scopus 로고
    • Highly conserved 3′ UTR and expression pattern of FXR1 points to a divergent gene regulation of FXR1 and FMR1
    • Coy, J.F., Sedlacek, Z., Bächner, D., Hameister, H., Joos, S., Lichter, P., Delius, H. and Poustka, A. (1995) Highly conserved 3′ UTR and expression pattern of FXR1 points to a divergent gene regulation of FXR1 and FMR1. Hum. Mol. Genet., 4, 2209-2218.
    • (1995) Hum. Mol. Genet. , vol.4 , pp. 2209-2218
    • Coy, J.F.1    Sedlacek, Z.2    Bächner, D.3    Hameister, H.4    Joos, S.5    Lichter, P.6    Delius, H.7    Poustka, A.8
  • 18
    • 0020533496 scopus 로고
    • Serum-induced stimulation of nucleoplasmic and nucleolar transcription in mouse 3T3 fibroblasts revisited
    • Tiercy, J.-M. and Weil, R. (1983) Serum-induced stimulation of nucleoplasmic and nucleolar transcription in mouse 3T3 fibroblasts revisited. Eur. J. Biochem., 131, 47-55.
    • (1983) Eur. J. Biochem. , vol.131 , pp. 47-55
    • Tiercy, J.-M.1    Weil, R.2
  • 19
    • 0019944957 scopus 로고
    • Intermediate filament systems are collapsed onto the nuclear surface after isolation of nuclei from tissue culture cells
    • Staufenbiel, M. and Deppert, W. (1982) Intermediate filament systems are collapsed onto the nuclear surface after isolation of nuclei from tissue culture cells. Exp. Cell Res., 138, 207-214.
    • (1982) Exp. Cell Res. , vol.138 , pp. 207-214
    • Staufenbiel, M.1    Deppert, W.2
  • 20
    • 0016156160 scopus 로고
    • Changes in RNA in relation to growth of the fibroblast. 1. Amounts of mRNA, rRNA, and tRNA in resting and growing cells
    • Johnson, L.F., Abelson, H.T., Green, H. and Penman, S. (1974) Changes in RNA in relation to growth of the fibroblast. 1. Amounts of mRNA, rRNA, and tRNA in resting and growing cells. Cell, 1, 95-100.
    • (1974) Cell , vol.1 , pp. 95-100
    • Johnson, L.F.1    Abelson, H.T.2    Green, H.3    Penman, S.4
  • 21
    • 0016375482 scopus 로고
    • Control of translation in cultured cells: Continued synthesis and accumulation of messenger RNA in nondividing cultures
    • Rudland, P.S. (1974) Control of translation in cultured cells: continued synthesis and accumulation of messenger RNA in nondividing cultures. Proc. Natl Acad. Sci. USA, 71, 750-754.
    • (1974) Proc. Natl Acad. Sci. USA , vol.71 , pp. 750-754
    • Rudland, P.S.1
  • 22
    • 0022981962 scopus 로고
    • Translational control of mRNA expression in Swiss mouse 3T3 cells: Identification of specific proteins
    • Thomas, G. and Thomas, G. (1986) Translational control of mRNA expression in Swiss mouse 3T3 cells: identification of specific proteins. J. Cell Biol., 103, 2137-2144.
    • (1986) J. Cell Biol. , vol.103 , pp. 2137-2144
    • Thomas, G.1    Thomas, G.2
  • 23
    • 0017328929 scopus 로고
    • Entry of mRNA into polyribosomes during recovery from starvation in mouse sarcoma 180 cells
    • Sonenshein, G. and Brawerman, G. (1977) Entry of mRNA into polyribosomes during recovery from starvation in mouse sarcoma 180 cells. Eur. J. Biochem., 73, 307-312.
    • (1977) Eur. J. Biochem. , vol.73 , pp. 307-312
    • Sonenshein, G.1    Brawerman, G.2
  • 24
    • 0016257578 scopus 로고
    • Isolation of messenger ribonucleoproteins from mammalian cells
    • Lindberg, U. and Sundquist, B. (1974) Isolation of messenger ribonucleoproteins from mammalian cells. J. Mol. Biol., 86, 451-468.
    • (1974) J. Mol. Biol. , vol.86 , pp. 451-468
    • Lindberg, U.1    Sundquist, B.2
  • 25
    • 0025760752 scopus 로고
    • Isolation of sequences that span the fragile X and identification of a fragile-X-related CpG island
    • Heitz, D., Rousseau, F., Devys, D., Saccone, S., Abderrahim, H., LePaslier, D. et al. (1991) Isolation of sequences that span the fragile X and identification of a fragile-X-related CpG island. Science, 251, 1236-1239.
    • (1991) Science , vol.251 , pp. 1236-1239
    • Heitz, D.1    Rousseau, F.2    Devys, D.3    Saccone, S.4    Abderrahim, H.5    LePaslier, D.6
  • 28
    • 0016666303 scopus 로고
    • Phosphorylation of messenger RNA-bound proteins in HeLa cells
    • Auerbach, S. and Pederson, T. (1975) Phosphorylation of messenger RNA-bound proteins in HeLa cells. Biochem. Biophys. Res. Commun., 63, 149-156.
    • (1975) Biochem. Biophys. Res. Commun. , vol.63 , pp. 149-156
    • Auerbach, S.1    Pederson, T.2
  • 29
    • 0017743716 scopus 로고
    • Specific poly-A-binding protein of 76,000 molecular weight in polyribosomes is not present on poly A of free cytoplasmic mRNP
    • van Venrooij, W.J., van Eekelen, C.A.G., Jansen, R.T.P. and Princen, J.M.G. (1977) Specific poly-A-binding protein of 76,000 molecular weight in polyribosomes is not present on poly A of free cytoplasmic mRNP. Nature, 270, 189-191.
    • (1977) Nature , vol.270 , pp. 189-191
    • Van Venrooij, W.J.1    Van Eekelen, C.A.G.2    Jansen, R.T.P.3    Princen, J.M.G.4
  • 30
    • 0025290642 scopus 로고
    • Do the poly(A) tail and 3′ untranslated region control mRNA translation?
    • Jackson, R.J. and Standart, N. (1990) Do the poly(A) tail and 3′ untranslated region control mRNA translation? Cell, 62, 15-24.
    • (1990) Cell , vol.62 , pp. 15-24
    • Jackson, R.J.1    Standart, N.2
  • 31
    • 0029130169 scopus 로고
    • The HIV-1 Rev activation domain is a nuclear export signal that accesses an export pathway used by specific cellular RNAs
    • Fischer, U., Huber, J., Boelens, W.C., Mattaj, I.W. and Lührmann. R. (1995) The HIV-1 Rev activation domain is a nuclear export signal that accesses an export pathway used by specific cellular RNAs. Cell, 82, 475-483.
    • (1995) Cell , vol.82 , pp. 475-483
    • Fischer, U.1    Huber, J.2    Boelens, W.C.3    Mattaj, I.W.4    Lührmann, R.5
  • 32
    • 0029130168 scopus 로고
    • Identification of a signal for rapid export of proteins from the nucleus
    • Wen, W., Meinkoth, J.L., Tsien, R. and Taylor, S.S. (1995) Identification of a signal for rapid export of proteins from the nucleus. Cell, 82, 463-473.
    • (1995) Cell , vol.82 , pp. 463-473
    • Wen, W.1    Meinkoth, J.L.2    Tsien, R.3    Taylor, S.S.4
  • 34
  • 35
    • 0000963145 scopus 로고
    • The Fragile X syndrome
    • Scriver, C.R., Beaudet, A.C., Sly, W.S. and Valle, D. (eds). McGraw-Hill Inc. New York, 7th edn.
    • Nussbaum, R.L. and Ledbetter, D.H. (1995) The Fragile X syndrome. In Scriver, C.R., Beaudet, A.C., Sly, W.S. and Valle, D. (eds). The Metabolic and Molecular Bases of Inheritend Disease. McGraw-Hill Inc. New York, 7th edn., vol.1, pp. 795-810.
    • (1995) The Metabolic and Molecular Bases of Inheritend Disease , vol.1 , pp. 795-810
    • Nussbaum, R.L.1    Ledbetter, D.H.2
  • 36
    • 0001966753 scopus 로고    scopus 로고
    • Physical and behavioral phenotype
    • Hagerman, R.J. and Cronister, A. (eds). The Johns Hopkins University Press, Baltimore and London
    • Hagerman, R.J. (1996) Physical and behavioral phenotype. In Hagerman, R.J. and Cronister, A. (eds). Fragile X syndrome: Diagnosis, Treatment and Research. The Johns Hopkins University Press, Baltimore and London, pp. 3-87.
    • (1996) Fragile X Syndrome: Diagnosis, Treatment and Research , pp. 3-87
    • Hagerman, R.J.1
  • 37
    • 0022484665 scopus 로고
    • UV crosslinking of RNA to nylon membrane enhances hybridization signals
    • Khandjian, E.W. (1986) UV crosslinking of RNA to nylon membrane enhances hybridization signals. Mol. Biol. Rep., 11, 107-115.
    • (1986) Mol. Biol. Rep. , vol.11 , pp. 107-115
    • Khandjian, E.W.1
  • 38
    • 0025177034 scopus 로고
    • Oncogenic activation of the human trk proto-oncogene by recombination with the ribosomal large subunit protein L7a
    • Ziemiecki, A., Müller, R.G., Xiao-Chang, F., Hynes, N.E. and Kozma, S. (1990) Oncogenic activation of the human trk proto-oncogene by recombination with the ribosomal large subunit protein L7a. EMBO J., 9, 191-196.
    • (1990) EMBO J. , vol.9 , pp. 191-196
    • Ziemiecki, A.1    Müller, R.G.2    Xiao-Chang, F.3    Hynes, N.E.4    Kozma, S.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.