Quantitative Analyses of Core Promoters Enable Precise Engineering of Regulated Gene Expression in Mammalian Cells

ACS Synthetic Biology

Volumn 5, Issue 5, 2016, Pages 395-404

  Ede, Christopher ^a   Chen, Ximin ^a   Lin, Meng Yin ^a   Chen, Yvonne Y ^a  

^a Engineering IV   (United States)

Author keywords

adoptive T cell therapy; chimeric antigen receptors; mammalian inducible promoters; mammalian synthetic biology; transcriptional control

Indexed keywords

CHIMERIC ANTIGEN RECEPTOR; HERPES SIMPLEX THYMIDINE KINASE; THYMIDINE KINASE; TRANSCRIPTION FACTOR JUNB; UNCLASSIFIED DRUG; LYMPHOCYTE ANTIGEN RECEPTOR;

ANIMAL CELL; ARTICLE; BINDING SITE; CELL ENGINEERING; CONTROLLED STUDY; DNA RESPONSIVE ELEMENT; GENE DOSAGE; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; HEK293 CELL LINE; HUMAN; HUMAN CELL; HYPOXIA; IMMUNOSTIMULATION; JURKAT CELL LINE; MICROENVIRONMENT; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; QUANTITATIVE ANALYSIS; SIMIAN VIRUS 40; ANIMAL; CALIBRATION; GENE EXPRESSION; GENETICS; MAMMAL; METABOLISM; PROCEDURES; SYNTHETIC BIOLOGY; T LYMPHOCYTE;

ANIMALS; CALIBRATION; GENE DOSAGE; GENE EXPRESSION; HUMANS; MAMMALS; PROMOTER REGIONS, GENETIC; RECEPTORS, ANTIGEN; SYNTHETIC BIOLOGY; T-LYMPHOCYTES; TRANSCRIPTION, GENETIC;

EID: 84973165904     PISSN: None     EISSN: 21615063     Source Type: Journal    
DOI: 10.1021/acssynbio.5b00266     Document Type: Article

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