Molecular dissection of the intrinsic factor-vitamin B12 receptor, cubilin, discloses regions important for membrane association and ligand binding

Journal of Biological Chemistry

Volumn 274, Issue 29, 1999, Pages 20540-20544

  Kristiansen, Mette ^a   Kozyraki, Renata ^a   Jacobsen, Christian ^a   Nexø, Ebba ^b   Verroust, Pierre J ^c   Moestrup, Søren K ^a  

^a AARHUS UNIVERSITY   (Denmark)

^b AARHUS UNIVERSITY HOSPITAL   (Denmark)

^c HÔPITAL TENON   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CUBILIN; CYANOCOBALAMIN; INTRINSIC FACTOR; RECEPTOR PROTEIN; UNCLASSIFIED DRUG; VITAMIN RECEPTOR;

ANIMAL CELL; ARTICLE; BINDING SITE; LIGAND BINDING; MEMBRANE BINDING; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; STRUCTURE ANALYSIS;

AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; CELL MEMBRANE; CHO CELLS; CRICETINAE; HUMANS; INTRINSIC FACTOR; LIGANDS; MEMBRANE GLYCOPROTEINS; MOLECULAR SEQUENCE DATA; RECEPTORS, CELL SURFACE; RECOMBINANT PROTEINS; SURFACE PLASMON RESONANCE; SWINE; VITAMIN B 12;

ANIMALIA; CRICETINAE; CRICETULUS GRISEUS;

EID: 0033575195     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.274.29.20540     Document Type: Article

References (23)

1. Nexø, E. (1998) in Vitamin B12 and B12 Proteins (Kräutler, B., Adrigoni, D., and Golding B. T., eds) pp. 461-475, Wiley-vch Verlag, Weinheim, Germany
2. Seetharam B., Seetharam, S., Li, N., and Ramanujam, K. S. (1994) in Advances in Thomas Addison's Diseases (Bhatt H. R., James, V. H. T., Besser, G. M., Bottazo, G. F., and Keen H., eds) Vol II, pp. 393-406, Journal of Endocrinology Ltd., Bristol, UK
3. Moestrup, S. K. in Vitamin B12 and B12 Proteins (Kräutler, B., Adrigoni, D., and Golding B. T., eds) pp. 477-489, Wiley-vch Verlag, Weinheim, Germany
4. Tang, L. H., Chokshi, H., Hu, C. B., Gordon, M. M., and Alpers, D. H. (1992) J. Biol. Chem. 267, 22982-22986
5. Birn, H., Verroust, P. J., Nexø, E., Hager, H., Jacobsen, C., Christensen, E. I., and Moestrup, S. K. (1997) J. Biol. Chem. 272, 26497-26504
6. Gueant, J. L., Saunier, M., Gastin, I., Safi, A., Lamireau, T., Duclos, B., Bigard, M. A., and Grasbeck, R. (1995) Gastroenterology 108, 1622-1628
7. Fyfe, J. C., Ramanujam, K. S., Ramasamy, M., Patterson, D. F., and Seetharam B. (1991) J. Biol. Chem. 266, 4489-4494
8. Yang, Y. M., Ducos, R., Rosenberg, A. J., Catrou, P. G., Levine, J. S., Podell, E. R., and Allen, R. H. (1985) J. Clin. Invest. 76, 2057-2065
9. Imerslund, O. (1960) Acta Paediatr. Scand. 49, 1-115
10. Grasbeck, G. R. (1960) Acta Med. Scand. 167, 289-296
11. Aminoff, M., Carter, J. E., Chadwick, R., Grasbeck, R., Abdelaal, M. A., Broch, H., Jenner, L. B., Verroust, P. J., Moestrup, S. K., de la Chapelle, A., and Krahe, R. (1999) Nat. Genet., 21, 309-313
12. Sahali, D., Mulliez, N., Chatelet, F., Dupuis, R., Ronco, P., and Verroust, P. (1988) J. Exp. Med. 167, 213-218
13. Moestrup, S. K., Kozyraki, R., Kristiansen, M., Kaysen, J. H., Rasmussen, H. H., Brault, D., Pontillon, F., Goda, F. O., Christensen, E. I., Hammond, T. G., and Verroust, P. J. (1998) J. Biol. Chem. 273, 5235-5242
14. Kozyraki, R., Kristiansen, M., Silahtaroglu, A., Hansen, C., Jacobsen, C., Tommerup, N., Verroust, P. J., and Moestrup, S. K. (1998) Blood 91, 3593-3600
15. Gliemann, J. (1998) Biol. Chem. 379, 951-964
16. Nexø, E., and Olesen, H. (1976) Biochim. Biophys. Acta 446, 143-147
17. Segrest, J. P., De-Loof, H., Dohlman, J. G., Brouillette, C. G., and Anantharamaiah, G. M. (1990) Proteins 8, 103-117
18. Lindblom, A., Quadt, N., Marsh, T., Aeschlimann, D., Mörgelin, M., Mann, K., Maurer, P., and Paulsson (1999) J. Biol. Chem. 274, 6374-6380
19. Cheng, H., Bjerknes, M., and Chen, H. (1996) Anat. Rec. 244, 327-343
20. Dias, J., M., Carvalho, A. L., Kolin, I., Calvete, J. J., Topfer, P. E., Varela, P. F., Romero, A., Urbanke, C., and Romao, M. J. (1997) Protein Sci. 6, 725-727
21. Varela, P. F., Romero, A., Sanz, L., Romao, M. J., Topfer, P. E., and Calvete, J. J. (1997) J. Mol. Biol. 274, 635-649
22. Willnow, T. E., Armstrong, S. A., Hammer, R. E., and Herz, J. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 4537-4541
23. Herz, J., Hamann, V., Rogne, S. and Myklebost, O., Gausepohl, M., and Stanley, K. K. (1988) EMBO J. 7, 4119-4127