Tissue distribution of human gp330/megalin, a putative Ca2+-sensing protein

Journal of Histochemistry and Cytochemistry

Volumn 45, Issue 3, 1997, Pages 383-392

  Lundgren, Stefan ^a   Carling, Tobias ^b   Hjälm, Göran ^b   Juhlin, Claes ^b   Rastad, Jonas ^b   Pihlgren, Ulla ^a   Rask, Lars ^b   Åkerström, Göran ^b   Hellman, Per ^b,c  

^a SWEDISH UNIVERSITY OF AGRICULTURAL SCIENCES   (Sweden)

^b UPPSALA UNIVERSITY   (Sweden)

^c UPPSALA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Ca2+ sensing; human; immunohistochemistry; in situ hybridization; parathyroid hormone related protein; tissue distribution

Indexed keywords

CALCIUM ION; GLYCOPROTEIN; MEGALIN; PARATHYROID HORMONE RELATED PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; BREAST EPITHELIUM; CALCIUM HOMEOSTASIS; CILIATED EPITHELIUM; CONTROLLED STUDY; CYTOTROPHOBLAST; DNA SEQUENCE; EPIDIDYMIS; EXTRACELLULAR CALCIUM; HUMAN; HUMAN TISSUE; IN SITU HYBRIDIZATION; KIDNEY PROXIMAL TUBULE; LUNG ALVEOLUS CELL TYPE 2; PARATHYROID CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; THYROID FOLLICLE CELL; TISSUE DISTRIBUTION;

EID: 0030939660     PISSN: 00221554     EISSN: None     Source Type: Journal    
DOI: 10.1177/002215549704500306     Document Type: Article

References (38)

1. Brown EM (1994) Homeostatic mechanisms regulating extracellular and intracellular calcium metabolism. In Bilezikian JP, Levine MA, Marcus R, eds. The Parathyroids. New York, Raven Press, 15-54
2. Brown E (1991) Extracellular Ca2+ sensing, regulation of parathyroid cell function, and role of Ca2+ and other ions as extracellular (first) messengers. Physiol Rev 71:371-411
3. Brown EM, Chen CJ, Kifor O, LeBoff MS, El-Hajj G, Fajtova V, Rubin LT (1990) Ca2+-sensing, second messengers, and the control of parathyroid hormone secretion. Cell Calcium 11:333-337
4. Brown EM, Gamba G, Riccardi D, Lombardi M, Butters R, Kifor O, Sun A, Hediger MA, Lytton J, Hebert SC (1993) Cloning and characterization of an extracellular Ca(2+)-sensing receptor from bovine parathyroid. Nature 366:575-580
5. Budayr AA, Halloran BP, King JC, Diep D, Nissenson RA, Trewler GJ (1989) High levels of a parathyroid hormone-like protein in milk. Proc Natl Acad Sci USA 86:7183-7185
6. Christensen El, Gliemann J, Moestrup SK (1992) Renal tubule gp330 is a calcium binding receptor for endocytic uptake of protein. J Histochem Cytochem 40:1481-1490
7. Cox HK, Goldberg BR (1988) Analysis of plant gene expression. In Shaw CH, ed. Plant Molecular Biology: A Practical Approach. Oxford, IRL Press, 1-34
8. Farquhar MG, Kerjaschki D, Lundstrom M, A OR (1994) Gp330 and RAP: the Heymann nephritis antigenic complex. Ann NY Acad Sci 737:96-113
9. Gylfe E, Åkerstrom G, Juhlin C, Klareskog L, Rastad J (1990) Regulation of cytoplasmic Ca2+ and hormone release of the parathyroid cell. In Dumont JE, Nunez J, King RJB, eds. Hormones and Cell Regulation. London, John Libbey Eurotext, 5-15
10. Gylfe E, Johansson H, Larsson R, Nygren P, Rastad J, Wallfelt C, Åkerström G (1987) Activation of Ca2+ influx into parathyroid cells by external cation binding. In Conn DV, Martin TJ, Meunier PJ, eds. Calcium Regulation and Bone Metabolism: Basic and Clinical Aspects. Amsterdam, Elsevier, 33-38
11. Hastings RH, Summers-Torres D, Ditmer LS, Burton DW, Cheung TC, Spragg RG, Brown EM, Deftos LJ (1995) Pulmonary alveolar epithelial cells express functional PTHrP-calcium-surfactant regulation loop. J Bone Miner Res 10(suppl 1):S382
12. Hellman P, Bjerneroth G, Juhlin C, Ridefelt P, Rastad J, Åkerström G, Jüppner H (1990) Immunohistochemical evidence of parathyroid hormone-related protein in human parathyroid tissue. Endocrine Pathol 1:172-176
13. Hellman P, Hellman B, Jüppner H, Ridefelt P, Rastad J, Åkerström G (1993) Regulation of proliferation in JEG-3 cells by a 500 kDa Ca2+-sensor and parathyroid hormone-related protein. Arch Biochem Biophys 307:379-385
14. Hellman P, Ridefelt P, Juhlin C, Åkerström G, Rastad J, Gylfe E (1992) Parathyroid-like regulation of parathyroid hormone-related protein release and cytoplasmic calcium in cytotrophoblast cells of human placenta. Arch Biochem Biophys 293:174-180
15. Johnson JA, Grande JP, Roche PC, Campbell RJ, Kumar R (1995) Immunolocalization of the calcitriol receptor, calbindin-28k and the plasma membrane calcium pump in the human eye. Curr Eye Res 14:101-108
16. Juhlin C, Holmdahl R, Johansson H, Rastad J, Åkerström G, Klareskog L (1987a) Monoclonal antibodies with exclusive reactivity against parathyroid cells and tubule cells of the kidney. Proc Natl Acad Sci USA 84:2990-2994
17. Juhlin C, Johansson H, Holmdahl R, Gylfe E, Larsson R, Rastad J, Åkerström G, Klareskog L (1987b) Monoclonal antiparathyroid antibodies interfering with a Ca2+-sensor of human parathyroid cells. Biochem Biophys Res Commun 143:570-574
18. Juhlin C, Klareskog L, Nygren P, Ljunghall S, Gylfe E, Rastad J, Åkerström G (1988) Hyperparathyroidism is associated with reduced expression of a parathyroid calcium receptor mechanism defined by monoclonal antiparathyroid antibodies. Endocrinology 122:2999-3001
19. Juhlin C, Lundgren S, Johansson H, Lorentzen J, Rask L, Larsson E, Rastad J, Äkerström G, Klareskog L (1990) 500-kilodalton calcium sensor regulating cytoplasmic Ca2+ in cytotrophoblast cells of human placenta. J Biol Chem 265:8275-8279
20. Juhlin C, Rastad J, Klareskog L, Grimelius L, Åkerström G (1989) Parathyroid histology and cytology with monoclonal antibodies recognizing a calcium sensor of parathyroid cells. Am J Pathol 135:321-328
21. Kifor O, Moore FD, Wang P, Goldstein M, Vassilev P, Kifor I, Hebert SC, Brown EM (1996) Reduced immunostaining for the extracellular Ca2+-sensing receptor in primary and uremic secondary hyperparathyroidism. Endocrinology 81:1598-1606
22. Kounnas MZ, Loukinova EB, Stefansson S, Harmony JA, Brewer BH, Strickland DK, Argraves WS (1995) Identification of glycoprotein 330 as an endocytic receptor for apolipoprotein J/clusterin. J Biol Chem 270:13070-13075
23. Lundgren S, Hjälm G, Hellman P, Ek B, Juhlin C, Rastad J, Klareskog L, Åkerström G, Rask L (1994) A protein involved in calcium sensing of the human parathyroid and placental cytotrophoblast cells belonging to the LDL-receptor superfamily. Exp Cell Res 212:344-350
24. Maniatis T, Fritsch EF, Sambrook J (1982) Molecular Cloning: A Laboratory Manual. Cold Spring Harbor, NY, Cold Spring Harbor Laboratory Press
25. Mathias RS, Brown EM (1991) Divalent cations modulate PTH-dependent 3′,5′-cyclic adenosine monophosphate production in renal proximal tubular cells. Endocrinology 128:3005-3012
26. Nemeth E, Scarpa A (1987) Rapid mobilization of cellular Ca2+ in bovine parathyroid cells evoked by extracellular divalent cations. J Biol Chem 262:5188-5196
27. Nygren P, Gylfe E, Larsson R, Johansson H, Juhlin C, Klareskog L, Åkerström G, Rastad J (1988) Modulation of the Ca2+-sensing function of parathyroid cells in vitro and in hyperparathyroidism. Biochim Biophys Acta 968:253-260
28. Raychowdhury R, Niles JL, McCluskey RT, Smith JA (1989) Autoimmune target in Heymann nephritis is a glycoprotein with homology to the LDL receptor. Science 244:1163-1165
29. Rodda CP, Kubota M, Heath JA, Ebeling PR, Moseley JM, Care AD, Caple IW, Martin TJ (1988) Evidence for a novel parathyroid hormone-related protein in fetal lamb parathyroid glands and sheep placenta: comparisons with a similar protein implicated in humoral hypercalcemia of malignancy. J Endocrinol 117:261-271
30. Rubin LP, Kifor O, Hua J, Brown EM, Torday JS (1994) Parathyroid hormone (PTH) and PTH-related protein stimulate surfactant phospholipid synthesis in rat fetal lung, apparently by a mesenchymal-epithelial mechanism. Biochim Biophys Acta 1223:91-100
31. Rudberg C, Grimelius L, Johansson H, Ljunghall S, Odselius R, Pertoft H, Wide L, Åkerström G (1986) Alterations in density, morphology and parathyroid hormone release of dispersed parathyroid cells from patients with hyperparathyroidism. Acta Pathol Microbiol Immunol Scand [A] 94:253-261
32. Saito A, Pietromonaco S, Kwor-Chieh Loo A, Farquhar MG (1994) Complete cloning and sequencing of rat gp330/"megalin," a distinctive member of the low density lipoprotein receptor gene family. Proc Natl Acad Sci USA 91:9725-9731
33. Sakaguchi K, Ikeda K, Curcio F, Aurbach CD, Brandi ML (1990) Subclones of a rat parathyroid cell line (PT-r): regulation of growth and production of parathyroid hormone-related peptide (PTHrp). J Bone Miner Res 5:863-869
34. Schmeltzer E, Jahnen W, Hahlbrock K (1988) In situ localization of light induced chalcone synthase mRNA, chalcone synthase, and flavonide and products in epidermal cells of parsley leaves. Proc Natl Acad Sci USA 85:2989-2993
35. Schmeltzer E, Kruger-Lebus S, Hahlbrock K (1989) Temporal and spatial patterns of gene expression around sites of attempted fungal infection in parsley leaves. Plant Cell 17:993-1001
36. Williams SE, Kounnas MZ, Argraves WS, Strickland DK (1994) The α2-macroglobulin receptor/low density lipoprotein receptor-related protein and the receptor-associated protein. In Borth W, Feinman RD, Gonias SL, Quigley JP, Strickland DK, eds. Biology of α2-macroglobulin, Its Receptor and Related Proteins. Ann NY Acad Sci 1-26
37. Willnow TE, Rohlman A, Horton J, Otani H, Braun JR, Hammer RE, Herz J (1996) RAP, a specialized chaperone, prevents ligand-induced ER retention and degradation of LDL receptor-related endocytic receptors. EMBO J 15:26332-26339
38. Zheng G, Bachinsky DR, Stamenkovic I, Strickland DK, Brown D, Andres G, McCluskey RT (1994) Organ distribution in rats of two members of the low-density lipoprotein receptor gene family, Gp330 and LRP/α2MR, and the receptor-associated protein (RAP). J Histochem Cytochem 42:531-542