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Volumn 7, Issue 13, 2016, Pages 15444-15459

Tumor resistance to vascular disrupting agents: Mechanisms, imaging, and solutions

Author keywords

Imaging; Resistance; Solutions; Vascular disrupting agents

Indexed keywords

ANGIOGENESIS INHIBITOR; ANTINEOPLASTIC AGENT; IODINE 131; TUMOR MARKER; VASCULAR TARGETING AGENT;

EID: 84971606511     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.6999     Document Type: Article
Times cited : (45)

References (119)
  • 1
    • 69349095364 scopus 로고    scopus 로고
    • Anticancer strategies involving the vasculature
    • Heath VL, Bicknell R. Anticancer strategies involving the vasculature. Nat Rev Clin Oncol. 2009; 6:395-404.
    • (2009) Nat Rev Clin Oncol , vol.6 , pp. 395-404
    • Heath, V.L.1    Bicknell, R.2
  • 2
    • 0020449692 scopus 로고
    • Endothelial-cell proliferation in experimental tumours
    • Denekamp J, Hobson B. Endothelial-cell proliferation in experimental tumours. Br J Cancer. 1982; 46:711-20.
    • (1982) Br J Cancer , vol.46 , pp. 711-720
    • Denekamp, J.1    Hobson, B.2
  • 3
    • 0028929803 scopus 로고
    • Angiogenesis in cancer, vascular, rheumatoid and other disease
    • Folkman J. Angiogenesis in cancer, vascular, rheumatoid and other disease. Nat Med. 1995; 1:27-31.
    • (1995) Nat Med , vol.1 , pp. 27-31
    • Folkman, J.1
  • 4
    • 31144458716 scopus 로고    scopus 로고
    • How Avastin potentiates chemotherapeutic drugs: action and reaction in antiangiogenic therapy
    • Blagosklonny MV. How Avastin potentiates chemotherapeutic drugs: action and reaction in antiangiogenic therapy. Cancer biology & therapy. 2005; 4:1307-10.
    • (2005) Cancer biology & therapy , vol.4 , pp. 1307-1310
    • Blagosklonny, M.V.1
  • 5
    • 1642472018 scopus 로고    scopus 로고
    • Antiangiogenic therapy and tumor progression
    • Blagosklonny MV. Antiangiogenic therapy and tumor progression. Cancer Cell. 2004; 5:13-7.
    • (2004) Cancer Cell , vol.5 , pp. 13-17
    • Blagosklonny, M.V.1
  • 7
    • 0035417875 scopus 로고    scopus 로고
    • Mechanisms associated with tumor vascular shut-down induced by combretastatin A-4 phosphate: intravital microscopy and measurement of vascular permeability
    • Tozer GM, Prise VE, Wilson J, Cemazar M, Shan S, Dewhirst MW, Barber PR, Vojnovic B, Chaplin DJ. Mechanisms associated with tumor vascular shut-down induced by combretastatin A-4 phosphate: intravital microscopy and measurement of vascular permeability. Cancer Res. 2001; 61:6413-22.
    • (2001) Cancer Res , vol.61 , pp. 6413-6422
    • Tozer, G.M.1    Prise, V.E.2    Wilson, J.3    Cemazar, M.4    Shan, S.5    Dewhirst, M.W.6    Barber, P.R.7    Vojnovic, B.8    Chaplin, D.J.9
  • 9
    • 84875399800 scopus 로고    scopus 로고
    • Mechanisms of tumor resistance to small-molecule vascular disrupting agents: treatment and rationale of combination therapy
    • Wu XY, Ma W, Gurung K, Guo CH. Mechanisms of tumor resistance to small-molecule vascular disrupting agents: treatment and rationale of combination therapy. Journal of the Formosan Medical Association = Taiwan yi zhi. 2013; 112:115-24.
    • (2013) Journal of the Formosan Medical Association = Taiwan yi zhi , vol.112 , pp. 115-124
    • Wu, X.Y.1    Ma, W.2    Gurung, K.3    Guo, C.H.4
  • 10
    • 0031770618 scopus 로고    scopus 로고
    • The effect of combretastatin A-4 disodium phosphate in a C3H mouse mammary carcinoma and a variety of murine spontaneous tumors
    • Horsman MR, Ehrnrooth E, Ladekarl M, Overgaard J. The effect of combretastatin A-4 disodium phosphate in a C3H mouse mammary carcinoma and a variety of murine spontaneous tumors. Int J Radiat Oncol Biol Phys. 1998; 42:895-8.
    • (1998) Int J Radiat Oncol Biol Phys , vol.42 , pp. 895-898
    • Horsman, M.R.1    Ehrnrooth, E.2    Ladekarl, M.3    Overgaard, J.4
  • 11
    • 14844325322 scopus 로고    scopus 로고
    • Tumour parameters affected by combretastatin A-4 phosphate therapy in a human colorectal xenograft model in nude mice
    • El-Emir E, Boxer GM, Petrie IA, Boden RW, Dearling JL, Begent RH, Pedley RB. Tumour parameters affected by combretastatin A-4 phosphate therapy in a human colorectal xenograft model in nude mice. Eur J Cancer. 2005; 41:799-806.
    • (2005) Eur J Cancer , vol.41 , pp. 799-806
    • El-Emir, E.1    Boxer, G.M.2    Petrie, I.A.3    Boden, R.W.4    Dearling, J.L.5    Begent, R.H.6    Pedley, R.B.7
  • 13
    • 0038037735 scopus 로고    scopus 로고
    • Regulation of angiogenesis by hypoxia: role of the HIF system
    • Pugh CW, Ratcliffe PJ. Regulation of angiogenesis by hypoxia: role of the HIF system. Nat Med. 2003; 9:677-84.
    • (2003) Nat Med , vol.9 , pp. 677-684
    • Pugh, C.W.1    Ratcliffe, P.J.2
  • 15
    • 0035019116 scopus 로고    scopus 로고
    • Combretastatin A-4 prodrug inhibits growth of human non-small cell lung cancer in a murine xenotransplant model
    • Boehle AS, Sipos B, Kliche U, Kalthoff H, Dohrmann P. Combretastatin A-4 prodrug inhibits growth of human non-small cell lung cancer in a murine xenotransplant model. The Annals of thoracic surgery. 2001; 71:1657-65.
    • (2001) The Annals of thoracic surgery , vol.71 , pp. 1657-1665
    • Boehle, A.S.1    Sipos, B.2    Kliche, U.3    Kalthoff, H.4    Dohrmann, P.5
  • 17
    • 0035432151 scopus 로고    scopus 로고
    • Hypoxia-inducible factor: Achilles' heel of antiangiogenic cancer therapy (review)
    • Blagosklonny MV. Hypoxia-inducible factor: Achilles' heel of antiangiogenic cancer therapy (review). International journal of oncology. 2001; 19:257-62.
    • (2001) International journal of oncology , vol.19 , pp. 257-262
    • Blagosklonny, M.V.1
  • 18
    • 47249148397 scopus 로고    scopus 로고
    • Prognostic role of tumor necrosis, microvessel density, vascular endothelial growth factor and hypoxia inducible factor-1alpha in patients with clear cell renal carcinoma after radical nephrectomy in a long term follow-up
    • Minardi D, Lucarini G, Filosa A, Milanese G, Zizzi A, Di Primio R, Montironi R, Muzzonigro G. Prognostic role of tumor necrosis, microvessel density, vascular endothelial growth factor and hypoxia inducible factor-1alpha in patients with clear cell renal carcinoma after radical nephrectomy in a long term follow-up. International journal of immunopathology and pharmacology. 2008; 21:447-55.
    • (2008) International journal of immunopathology and pharmacology , vol.21 , pp. 447-455
    • Minardi, D.1    Lucarini, G.2    Filosa, A.3    Milanese, G.4    Zizzi, A.5    Di Primio, R.6    Montironi, R.7    Muzzonigro, G.8
  • 20
    • 77956206294 scopus 로고    scopus 로고
    • Identification of a survival-independent metastasis-enhancing role of hypoxia-inducible factor-1alpha with a hypoxia-tolerant tumor cell line
    • Schelter F, Gerg M, Halbgewachs B, Schaten S, Gorlach A, Schrotzlmair F, Kruger A. Identification of a survival-independent metastasis-enhancing role of hypoxia-inducible factor-1alpha with a hypoxia-tolerant tumor cell line. The Journal of biological chemistry. 2010; 285:26182-9.
    • (2010) The Journal of biological chemistry , vol.285 , pp. 26182-26189
    • Schelter, F.1    Gerg, M.2    Halbgewachs, B.3    Schaten, S.4    Gorlach, A.5    Schrotzlmair, F.6    Kruger, A.7
  • 22
    • 77952455508 scopus 로고    scopus 로고
    • Hypoxia increases the metastatic ability of breast cancer cells via upregulation of CXCR4
    • Cronin PA, Wang JH, Redmond HP. Hypoxia increases the metastatic ability of breast cancer cells via upregulation of CXCR4. BMC Cancer. 2010; 10:225.
    • (2010) BMC Cancer , vol.10 , pp. 225
    • Cronin, P.A.1    Wang, J.H.2    Redmond, H.P.3
  • 25
    • 79957923609 scopus 로고    scopus 로고
    • Macrophage regulation of tumor angiogenesis: implications for cancer therapy
    • Squadrito ML, De Palma M. Macrophage regulation of tumor angiogenesis: implications for cancer therapy. Molecular aspects of medicine. 2011; 32:123-45.
    • (2011) Molecular aspects of medicine , vol.32 , pp. 123-145
    • Squadrito, M.L.1    De Palma, M.2
  • 26
    • 34347226359 scopus 로고    scopus 로고
    • Tumor-associated macrophages press the angiogenic switch in breast cancer
    • Lin EY, Pollard JW. Tumor-associated macrophages press the angiogenic switch in breast cancer. Cancer Res. 2007; 67:5064-6.
    • (2007) Cancer Res , vol.67 , pp. 5064-5066
    • Lin, E.Y.1    Pollard, J.W.2
  • 28
    • 34547125116 scopus 로고    scopus 로고
    • The vascular disrupting agent, DMXAA, directly activates dendritic cells through a MyD88-independent mechanism and generates antitumor cytotoxic T lymphocytes
    • Wallace A, LaRosa DF, Kapoor V, Sun J, Cheng G, Jassar A, Blouin A, Ching LM, Albelda SM. The vascular disrupting agent, DMXAA, directly activates dendritic cells through a MyD88-independent mechanism and generates antitumor cytotoxic T lymphocytes. Cancer Res. 2007; 67:7011-9.
    • (2007) Cancer Res , vol.67 , pp. 7011-7019
    • Wallace, A.1    LaRosa, D.F.2    Kapoor, V.3    Sun, J.4    Cheng, G.5    Jassar, A.6    Blouin, A.7    Ching, L.M.8    Albelda, S.M.9
  • 29
    • 34247117818 scopus 로고    scopus 로고
    • Endothelial progenitor cells in health and atherosclerotic disease
    • Werner N, Nickenig G. Endothelial progenitor cells in health and atherosclerotic disease. Annals of medicine. 2007; 39:82-90.
    • (2007) Annals of medicine , vol.39 , pp. 82-90
    • Werner, N.1    Nickenig, G.2
  • 31
    • 17044416487 scopus 로고    scopus 로고
    • The involvement of endothelial progenitor cells in tumor angiogenesis
    • Ribatti D. The involvement of endothelial progenitor cells in tumor angiogenesis. Journal of cellular and molecular medicine. 2004; 8:294-300.
    • (2004) Journal of cellular and molecular medicine , vol.8 , pp. 294-300
    • Ribatti, D.1
  • 38
    • 84866332370 scopus 로고    scopus 로고
    • Circulating endothelial progenitors and tumor resistance to vascular-targeting therapies
    • De Palma M, Nucera S. Circulating endothelial progenitors and tumor resistance to vascular-targeting therapies. Cancer discovery. 2012; 2:395-7.
    • (2012) Cancer discovery , vol.2 , pp. 395-397
    • De Palma, M.1    Nucera, S.2
  • 42
    • 33947540554 scopus 로고    scopus 로고
    • Detection of circulating endothelial cells: CD146-based magnetic separation enrichment or flow cytometric assay?
    • author reply e3-5
    • Dignat-George F, Sabatier F, Blann A, Woywodt A. Detection of circulating endothelial cells: CD146-based magnetic separation enrichment or flow cytometric assay? J Clin Oncol. 2007; 25: e1-2; author reply e3-5.
    • (2007) J Clin Oncol , vol.25 , pp. e1-e2
    • Dignat-George, F.1    Sabatier, F.2    Blann, A.3    Woywodt, A.4
  • 43
    • 20944436688 scopus 로고    scopus 로고
    • Differential effects of vascular endothelial growth factor receptor-2 inhibitor ZD6474 on circulating endothelial progenitors and mature circulating endothelial cells: implications for use as a surrogate marker of antiangiogenic activity
    • Beaudry P, Force J, Naumov GN, Wang A, Baker CH, Ryan A, Soker S, Johnson BE, Folkman J, Heymach JV. Differential effects of vascular endothelial growth factor receptor-2 inhibitor ZD6474 on circulating endothelial progenitors and mature circulating endothelial cells: implications for use as a surrogate marker of antiangiogenic activity. Clin Cancer Res. 2005; 11:3514-22.
    • (2005) Clin Cancer Res , vol.11 , pp. 3514-3522
    • Beaudry, P.1    Force, J.2    Naumov, G.N.3    Wang, A.4    Baker, C.H.5    Ryan, A.6    Soker, S.7    Johnson, B.E.8    Folkman, J.9    Heymach, J.V.10
  • 44
    • 33645732100 scopus 로고    scopus 로고
    • Phase I clinical evaluation of weekly administration of the novel vascular-targeting agent, ZD6126, in patients with solid tumors
    • Beerepoot LV, Radema SA, Witteveen EO, Thomas T, Wheeler C, Kempin S, Voest EE. Phase I clinical evaluation of weekly administration of the novel vascular-targeting agent, ZD6126, in patients with solid tumors. J Clin Oncol. 2006; 24:1491-8.
    • (2006) J Clin Oncol , vol.24 , pp. 1491-1498
    • Beerepoot, L.V.1    Radema, S.A.2    Witteveen, E.O.3    Thomas, T.4    Wheeler, C.5    Kempin, S.6    Voest, E.E.7
  • 47
    • 33846880876 scopus 로고    scopus 로고
    • Biomarkers for monitoring antiangiogenic therapy
    • Bhatt RS, Seth P, Sukhatme VP. Biomarkers for monitoring antiangiogenic therapy. Clin Cancer Res. 2007; 13:777s-80s.
    • (2007) Clin Cancer Res , vol.13 , pp. 777s-780s
    • Bhatt, R.S.1    Seth, P.2    Sukhatme, V.P.3
  • 48
    • 23944518957 scopus 로고    scopus 로고
    • Unresolved questions, changing definitions, and novel paradigms for defining endothelial progenitor cells
    • Ingram DA, Caplice NM, Yoder MC. Unresolved questions, changing definitions, and novel paradigms for defining endothelial progenitor cells. Blood. 2005; 106:1525-31.
    • (2005) Blood , vol.106 , pp. 1525-1531
    • Ingram, D.A.1    Caplice, N.M.2    Yoder, M.C.3
  • 49
    • 80054730707 scopus 로고    scopus 로고
    • Cancer Models-Multiparametric Applications of Clinical MRI in Rodent Hepatic Tumor Model
    • Edited by Schroeder L, Faber C. Berlin: Humana Press (part of the Springer publishing group)
    • Chen F, De Keyzer F, Ni Y: Cancer Models-Multiparametric Applications of Clinical MRI in Rodent Hepatic Tumor Model. In vivo MR Imaging: Methods and Protocols. Edited by Schroeder L, Faber C. Berlin: Humana Press (part of the Springer publishing group), 2011. pp. 489-507.
    • (2011) Vivo MR Imaging: Methods and Protocols , pp. 489-507
    • Chen, F.1    De Keyzer, F.2    Ni, Y.3
  • 55
    • 63449111973 scopus 로고    scopus 로고
    • Treatment of rodent liver tumor with combretastatin a4 phosphate: noninvasive therapeutic evaluation using multiparametric magnetic resonance imaging in correlation with microangiography and histology
    • Wang H, Sun X, Chen F, De Keyzer F, Yu J, Landuyt W, Vandecaveye V, Peeters R, Bosmans H, Hermans R, Marchal G, Ni Y. Treatment of rodent liver tumor with combretastatin a4 phosphate: noninvasive therapeutic evaluation using multiparametric magnetic resonance imaging in correlation with microangiography and histology. Invest Radiol. 2009; 44:44-53.
    • (2009) Invest Radiol , vol.44 , pp. 44-53
    • Wang, H.1    Sun, X.2    Chen, F.3    De Keyzer, F.4    Yu, J.5    Landuyt, W.6    Vandecaveye, V.7    Peeters, R.8    Bosmans, H.9    Hermans, R.10    Marchal, G.11    Ni, Y.12
  • 56
    • 2642571660 scopus 로고    scopus 로고
    • Vascular-targeting therapies for treatment of malignant disease
    • Siemann DW, Chaplin DJ, Horsman MR. Vascular-targeting therapies for treatment of malignant disease. Cancer. 2004; 100:2491-9.
    • (2004) Cancer , vol.100 , pp. 2491-2499
    • Siemann, D.W.1    Chaplin, D.J.2    Horsman, M.R.3
  • 57
    • 84871544671 scopus 로고    scopus 로고
    • Overcoming intratumor heterogeneity of polygenic cancer drug resistance with improved biomarker integration
    • Rehemtulla A. Overcoming intratumor heterogeneity of polygenic cancer drug resistance with improved biomarker integration. Neoplasia. 2012; 14:1278-89.
    • (2012) Neoplasia , vol.14 , pp. 1278-1289
    • Rehemtulla, A.1
  • 58
    • 84884377472 scopus 로고    scopus 로고
    • Tumour heterogeneity and cancer cell plasticity
    • Meacham CE, Morrison SJ. Tumour heterogeneity and cancer cell plasticity. Nature. 2013; 501:328-37.
    • (2013) Nature , vol.501 , pp. 328-337
    • Meacham, C.E.1    Morrison, S.J.2
  • 60
    • 84865413255 scopus 로고    scopus 로고
    • Percent change of perfusion skewness and kurtosis: a potential imaging biomarker for early treatment response in patients with newly diagnosed glioblastomas
    • Baek HJ, Kim HS, Kim N, Choi YJ, Kim YJ. Percent change of perfusion skewness and kurtosis: a potential imaging biomarker for early treatment response in patients with newly diagnosed glioblastomas. Radiology. 2012; 264:834-43.
    • (2012) Radiology , vol.264 , pp. 834-843
    • Baek, H.J.1    Kim, H.S.2    Kim, N.3    Choi, Y.J.4    Kim, Y.J.5
  • 61
    • 84865759728 scopus 로고    scopus 로고
    • Histogram analysis of apparent diffusion coefficient map of standard and high B-value diffusion MR imaging in head and neck squamous cell carcinoma: a correlation study with histological grade
    • Ahn SJ, Choi SH, Kim YJ, Kim KG, Sohn CH, Han MH, Chang KH, Min HS. Histogram analysis of apparent diffusion coefficient map of standard and high B-value diffusion MR imaging in head and neck squamous cell carcinoma: a correlation study with histological grade. Acad Radiol. 2012; 19:1233-40.
    • (2012) Acad Radiol , vol.19 , pp. 1233-1240
    • Ahn, S.J.1    Choi, S.H.2    Kim, Y.J.3    Kim, K.G.4    Sohn, C.H.5    Han, M.H.6    Chang, K.H.7    Min, H.S.8
  • 65
    • 84905053610 scopus 로고    scopus 로고
    • Breast cancer: early prediction of response to neoadjuvant chemotherapy using parametric response maps for MR imaging
    • Cho N, Im SA, Park IA, Lee KH, Li M, Han W, Noh DY, Moon WK. Breast cancer: early prediction of response to neoadjuvant chemotherapy using parametric response maps for MR imaging. Radiology. 2014; 272:385-96.
    • (2014) Radiology , vol.272 , pp. 385-396
    • Cho, N.1    Im, S.A.2    Park, I.A.3    Lee, K.H.4    Li, M.5    Han, W.6    Noh, D.Y.7    Moon, W.K.8
  • 68
    • 49049086508 scopus 로고    scopus 로고
    • Dual targeting of tumor vasculature: combining Avastin and vascular disrupting agents (CA4P or OXi4503)
    • Siemann DW, Shi W. Dual targeting of tumor vasculature: combining Avastin and vascular disrupting agents (CA4P or OXi4503). Anticancer research. 2008; 28:2027-31.
    • (2008) Anticancer research , vol.28 , pp. 2027-2031
    • Siemann, D.W.1    Shi, W.2
  • 69
    • 7444259131 scopus 로고    scopus 로고
    • Efficacy of combined antiangiogenic and vascular disrupting agents in treatment of solid tumors
    • Siemann DW, Shi W. Efficacy of combined antiangiogenic and vascular disrupting agents in treatment of solid tumors. Int J Radiat Oncol Biol Phys. 2004; 60:1233-40.
    • (2004) Int J Radiat Oncol Biol Phys , vol.60 , pp. 1233-1240
    • Siemann, D.W.1    Shi, W.2
  • 70
    • 37249045539 scopus 로고    scopus 로고
    • Consequences of increased vascular permeability induced by treatment of mice with 5,6-dimethylxanthenone-4-acetic acid (DMXAA) and thalidomide
    • Chung F, Liu J, Ching LM, Baguley BC. Consequences of increased vascular permeability induced by treatment of mice with 5,6-dimethylxanthenone-4-acetic acid (DMXAA) and thalidomide. Cancer chemotherapy and pharmacology. 2008; 61:497-502.
    • (2008) Cancer chemotherapy and pharmacology , vol.61 , pp. 497-502
    • Chung, F.1    Liu, J.2    Ching, L.M.3    Baguley, B.C.4
  • 73
    • 84891060305 scopus 로고    scopus 로고
    • Tumor delivery of chemotherapy combined with inhibitors of angiogenesis and vascular targeting agents
    • Cesca M, Bizzaro F, Zucchetti M, Giavazzi R. Tumor delivery of chemotherapy combined with inhibitors of angiogenesis and vascular targeting agents. Frontiers in oncology. 2013; 3:259.
    • (2013) Frontiers in oncology , vol.3 , pp. 259
    • Cesca, M.1    Bizzaro, F.2    Zucchetti, M.3    Giavazzi, R.4
  • 74
    • 67249095624 scopus 로고    scopus 로고
    • Combination of combretastatin A4 phosphate and doxorubicin-containing liposomes affects growth of B16-F10 tumors
    • Mitrus I, Sochanik A, Cichon T, Szala S. Combination of combretastatin A4 phosphate and doxorubicin-containing liposomes affects growth of B16-F10 tumors. Acta biochimica Polonica. 2009; 56:161-5.
    • (2009) Acta biochimica Polonica , vol.56 , pp. 161-165
    • Mitrus, I.1    Sochanik, A.2    Cichon, T.3    Szala, S.4
  • 75
    • 70350231754 scopus 로고    scopus 로고
    • Low-dose metronomic cyclophosphamide combined with vascular disrupting therapy induces potent antitumor activity in preclinical human tumor xenograft models
    • Daenen LG, Shaked Y, Man S, Xu P, Voest EE, Hoffman RM, Chaplin DJ, Kerbel RS. Low-dose metronomic cyclophosphamide combined with vascular disrupting therapy induces potent antitumor activity in preclinical human tumor xenograft models. Molecular cancer therapeutics. 2009; 8:2872-81.
    • (2009) Molecular cancer therapeutics , vol.8 , pp. 2872-2881
    • Daenen, L.G.1    Shaked, Y.2    Man, S.3    Xu, P.4    Voest, E.E.5    Hoffman, R.M.6    Chaplin, D.J.7    Kerbel, R.S.8
  • 81
    • 84880937489 scopus 로고    scopus 로고
    • Sequential systemic administrations of combretastatin A4 Phosphate and radioiodinated hypericin exert synergistic targeted theranostic effects with prolonged survival on SCID mice carrying bifocal tumor xenografts
    • Li J, Cona MM, Chen F, Feng Y, Zhou L, Zhang G, Nuyts J, de Witte P, Zhang J, Yu J, Oyen R, Verbruggen A, Ni Y. Sequential systemic administrations of combretastatin A4 Phosphate and radioiodinated hypericin exert synergistic targeted theranostic effects with prolonged survival on SCID mice carrying bifocal tumor xenografts. Theranostics. 2013; 3:127-37.
    • (2013) Theranostics , vol.3 , pp. 127-137
    • Li, J.1    Cona, M.M.2    Chen, F.3    Feng, Y.4    Zhou, L.5    Zhang, G.6    Nuyts, J.7    de Witte, P.8    Zhang, J.9    Yu, J.10    Oyen, R.11    Verbruggen, A.12    Ni, Y.13
  • 83
    • 79955764376 scopus 로고    scopus 로고
    • Small-animal PET of tumor damage induced by photothermal ablation with 64Cu-bis-DOTA-hypericin
    • Song S, Xiong C, Zhou M, Lu W, Huang Q, Ku G, Zhao J, Flores LG, Jr., Ni Y, Li C. Small-animal PET of tumor damage induced by photothermal ablation with 64Cu-bis-DOTA-hypericin. J Nucl Med. 2011; 52:792-9.
    • (2011) J Nucl Med , vol.52 , pp. 792-799
    • Song, S.1    Xiong, C.2    Zhou, M.3    Lu, W.4    Huang, Q.5    Ku, G.6    Zhao, J.7    Flores, L.G.8    Ni, Y.9    Li, C.10
  • 84
    • 84931085213 scopus 로고    scopus 로고
    • Necrosis targeted radiotherapy with iodine-131-labeled hypericin to improve anticancer efficacy of vascular disrupting treatment in rabbit VX2 tumor models
    • Shao H, Zhang J, Sun Z, Chen F, Dai X, Li Y, Ni Y, Xu K. Necrosis targeted radiotherapy with iodine-131-labeled hypericin to improve anticancer efficacy of vascular disrupting treatment in rabbit VX2 tumor models. Oncotarget. 2015; 6:14247-59. doi:10.18632/oncotarget.3679.
    • (2015) Oncotarget , vol.6 , pp. 14247-14259
    • Shao, H.1    Zhang, J.2    Sun, Z.3    Chen, F.4    Dai, X.5    Li, Y.6    Ni, Y.7    Xu, K.8
  • 87
    • 11844254414 scopus 로고    scopus 로고
    • Normalization of tumor vasculature: an emerging concept in antiangiogenic therapy
    • Jain RK. Normalization of tumor vasculature: an emerging concept in antiangiogenic therapy. Science. 2005; 307:58-62.
    • (2005) Science , vol.307 , pp. 58-62
    • Jain, R.K.1
  • 89
    • 27644436870 scopus 로고    scopus 로고
    • Optimal biologic dose of metronomic chemotherapy regimens is associated with maximum antiangiogenic activity
    • Shaked Y, Emmenegger U, Man S, Cervi D, Bertolini F, Ben-David Y, Kerbel RS. Optimal biologic dose of metronomic chemotherapy regimens is associated with maximum antiangiogenic activity. Blood. 2005; 106:3058-61.
    • (2005) Blood , vol.106 , pp. 3058-3061
    • Shaked, Y.1    Emmenegger, U.2    Man, S.3    Cervi, D.4    Bertolini, F.5    Ben-David, Y.6    Kerbel, R.S.7
  • 90
    • 0041589524 scopus 로고    scopus 로고
    • Maximum tolerable dose and low-dose metronomic chemotherapy have opposite effects on the mobilization and viability of circulating endothelial progenitor cells
    • Bertolini F, Paul S, Mancuso P, Monestiroli S, Gobbi A, Shaked Y, Kerbel RS. Maximum tolerable dose and low-dose metronomic chemotherapy have opposite effects on the mobilization and viability of circulating endothelial progenitor cells. Cancer Res. 2003; 63:4342-6.
    • (2003) Cancer Res , vol.63 , pp. 4342-4346
    • Bertolini, F.1    Paul, S.2    Mancuso, P.3    Monestiroli, S.4    Gobbi, A.5    Shaked, Y.6    Kerbel, R.S.7
  • 91
    • 34548506467 scopus 로고    scopus 로고
    • Tumor-host interaction in the optimization of paclitaxel-based combination therapies with vascular targeting compounds
    • Giavazzi R, Bani MR, Taraboletti G. Tumor-host interaction in the optimization of paclitaxel-based combination therapies with vascular targeting compounds. Cancer metastasis reviews. 2007; 26:481-8.
    • (2007) Cancer metastasis reviews , vol.26 , pp. 481-488
    • Giavazzi, R.1    Bani, M.R.2    Taraboletti, G.3
  • 92
    • 0036568457 scopus 로고    scopus 로고
    • Vascular targeting agents enhance chemotherapeutic agent activities in solid tumor therapy
    • Siemann DW, Mercer E, Lepler S, Rojiani AM. Vascular targeting agents enhance chemotherapeutic agent activities in solid tumor therapy. Int J Cancer. 2002; 99:1-6.
    • (2002) Int J Cancer , vol.99 , pp. 1-6
    • Siemann, D.W.1    Mercer, E.2    Lepler, S.3    Rojiani, A.M.4
  • 94
    • 0031775298 scopus 로고    scopus 로고
    • Enhancement of tumor radiation response by the antivascular agent 5,6-dimethylxanthenone-4-acetic acid
    • Wilson WR, Li AE, Cowan DS, Siim BG. Enhancement of tumor radiation response by the antivascular agent 5,6-dimethylxanthenone-4-acetic acid. Int J Radiat Oncol Biol Phys. 1998; 42:905-8.
    • (1998) Int J Radiat Oncol Biol Phys , vol.42 , pp. 905-908
    • Wilson, W.R.1    Li, A.E.2    Cowan, D.S.3    Siim, B.G.4
  • 95
    • 0034759198 scopus 로고    scopus 로고
    • Improved tumor response by combining radiation and the vascular-damaging drug 5,6-dimethylxanthenone-4-acetic acid
    • Murata R, Siemann DW, Overgaard J, Horsman MR. Improved tumor response by combining radiation and the vascular-damaging drug 5,6-dimethylxanthenone-4-acetic acid. Radiation research. 2001; 156:503-9.
    • (2001) Radiation research , vol.156 , pp. 503-509
    • Murata, R.1    Siemann, D.W.2    Overgaard, J.3    Horsman, M.R.4
  • 100
    • 0347123433 scopus 로고    scopus 로고
    • Tumour-educated macrophages promote tumour progression and metastasis
    • Pollard JW. Tumour-educated macrophages promote tumour progression and metastasis. Nat Rev Cancer. 2004; 4:71-8.
    • (2004) Nat Rev Cancer , vol.4 , pp. 71-78
    • Pollard, J.W.1
  • 101
    • 4444280232 scopus 로고    scopus 로고
    • Antitumor activity of ZD6126, a novel vascular-targeting agent, is enhanced when combined with ZD1839, an epidermal growth factor receptor tyrosine kinase inhibitor, and potentiates the effects of radiation in a human non-small cell lung cancer xenograft model
    • Raben D, Bianco C, Damiano V, Bianco R, Melisi D, Mignogna C, D'Armiento FP, Cionini L, Bianco AR, Tortora G, Ciardiello F, Bunn P. Antitumor activity of ZD6126, a novel vascular-targeting agent, is enhanced when combined with ZD1839, an epidermal growth factor receptor tyrosine kinase inhibitor, and potentiates the effects of radiation in a human non-small cell lung cancer xenograft model. Molecular cancer therapeutics. 2004; 3:977-83.
    • (2004) Molecular cancer therapeutics , vol.3 , pp. 977-983
    • Raben, D.1    Bianco, C.2    Damiano, V.3    Bianco, R.4    Melisi, D.5    Mignogna, C.6    D'Armiento, F.P.7    Cionini, L.8    Bianco, A.R.9    Tortora, G.10    Ciardiello, F.11    Bunn, P.12
  • 103
    • 33947309210 scopus 로고    scopus 로고
    • Chemosensitization and radiosensitization of human lung and colon cancers by antimitotic agent, ABT-751, in athymic murine xenograft models of subcutaneous tumor growth
    • Jorgensen TJ, Tian H, Joseph IB, Menon K, Frost D. Chemosensitization and radiosensitization of human lung and colon cancers by antimitotic agent, ABT-751, in athymic murine xenograft models of subcutaneous tumor growth. Cancer chemotherapy and pharmacology. 2007; 59:725-32.
    • (2007) Cancer chemotherapy and pharmacology , vol.59 , pp. 725-732
    • Jorgensen, T.J.1    Tian, H.2    Joseph, I.B.3    Menon, K.4    Frost, D.5
  • 104
    • 0031742231 scopus 로고    scopus 로고
    • Targeting the tumor vasculature with combretastatin A-4 disodium phosphate: effects on radiation therapy
    • Li L, Rojiani A, Siemann DW. Targeting the tumor vasculature with combretastatin A-4 disodium phosphate: effects on radiation therapy. Int J Radiat Oncol Biol Phys. 1998; 42:899-903.
    • (1998) Int J Radiat Oncol Biol Phys , vol.42 , pp. 899-903
    • Li, L.1    Rojiani, A.2    Siemann, D.W.3
  • 105
    • 84884547645 scopus 로고    scopus 로고
    • Induction of hypoxia by vascular disrupting agents and the significance for their combination with radiation therapy
    • Iversen AB, Busk M, Horsman MR. Induction of hypoxia by vascular disrupting agents and the significance for their combination with radiation therapy. Acta oncologica (Stockholm, Sweden). 2013; 52:1320-6.
    • (2013) Acta oncologica (Stockholm, Sweden) , vol.52 , pp. 1320-1326
    • Iversen, A.B.1    Busk, M.2    Horsman, M.R.3
  • 106
    • 0036569804 scopus 로고    scopus 로고
    • Enhancement of radiation therapy by the novel vascular targeting agent ZD6126
    • Siemann DW, Rojiani AM. Enhancement of radiation therapy by the novel vascular targeting agent ZD6126. Int J Radiat Oncol Biol Phys. 2002; 53:164-71.
    • (2002) Int J Radiat Oncol Biol Phys , vol.53 , pp. 164-171
    • Siemann, D.W.1    Rojiani, A.M.2
  • 107
    • 33751504322 scopus 로고    scopus 로고
    • Dependency of the effect of a vascular disrupting agent on sensitivity to tirapazamine and gamma-ray irradiation upon the timing of its administration and tumor size, with reference to the effect on intratumor quiescent cells
    • Masunaga S, Nagasawa H, Nagata K, Suzuki M, Uto Y, Hori H, Kinashi Y, Ono K. Dependency of the effect of a vascular disrupting agent on sensitivity to tirapazamine and gamma-ray irradiation upon the timing of its administration and tumor size, with reference to the effect on intratumor quiescent cells. Journal of cancer research and clinical oncology. 2007; 133:47-55.
    • (2007) Journal of cancer research and clinical oncology , vol.133 , pp. 47-55
    • Masunaga, S.1    Nagasawa, H.2    Nagata, K.3    Suzuki, M.4    Uto, Y.5    Hori, H.6    Kinashi, Y.7    Ono, K.8
  • 108
    • 20344394640 scopus 로고    scopus 로고
    • The vascular disrupting agent ZD6126 shows increased antitumor efficacy and enhanced radiation response in large, advanced tumors
    • Siemann DW, Rojiani AM. The vascular disrupting agent ZD6126 shows increased antitumor efficacy and enhanced radiation response in large, advanced tumors. Int J Radiat Oncol Biol Phys. 2005; 62:846-53.
    • (2005) Int J Radiat Oncol Biol Phys , vol.62 , pp. 846-853
    • Siemann, D.W.1    Rojiani, A.M.2
  • 109
  • 110
    • 42549099834 scopus 로고    scopus 로고
    • Photodynamic therapy of nonmelanoma skin cancer with topical hypericum perforatum extract-a pilot study
    • Kacerovska D, Pizinger K, Majer F, Smid F. Photodynamic therapy of nonmelanoma skin cancer with topical hypericum perforatum extract-a pilot study. Photochem Photobiol. 2008; 84:779-85.
    • (2008) Photochem Photobiol , vol.84 , pp. 779-785
    • Kacerovska, D.1    Pizinger, K.2    Majer, F.3    Smid, F.4
  • 111
    • 34247122660 scopus 로고    scopus 로고
    • Hypericin lights up the way for the potential treatment of nasopharyngeal cancer by photodynamic therapy
    • Olivo M, Du HY, Bay BH. Hypericin lights up the way for the potential treatment of nasopharyngeal cancer by photodynamic therapy. Curr Clin Pharmacol. 2006; 1:217-22.
    • (2006) Curr Clin Pharmacol , vol.1 , pp. 217-222
    • Olivo, M.1    Du, H.Y.2    Bay, B.H.3
  • 113
    • 78650298649 scopus 로고    scopus 로고
    • A phase II placebo-controlled study of photodynamic therapy with topical hypericin and visible light irradiation in the treatment of cutaneous T-cell lymphoma and psoriasis
    • Rook AH, Wood GS, Duvic M, Vonderheid EC, Tobia A, Cabana B. A phase II placebo-controlled study of photodynamic therapy with topical hypericin and visible light irradiation in the treatment of cutaneous T-cell lymphoma and psoriasis. J Am Acad Dermatol. 2010; 63:984-90.
    • (2010) J Am Acad Dermatol , vol.63 , pp. 984-990
    • Rook, A.H.1    Wood, G.S.2    Duvic, M.3    Vonderheid, E.C.4    Tobia, A.5    Cabana, B.6
  • 114
    • 43849086838 scopus 로고    scopus 로고
    • Hypericin as a marker for determination of tissue viability after radiofrequency ablation in a murine liver tumor model
    • Van de Putte M, Wang H, Chen F, De Witte PA, Ni Y. Hypericin as a marker for determination of tissue viability after radiofrequency ablation in a murine liver tumor model. Oncol Rep. 2008; 19:927-32.
    • (2008) Oncol Rep , vol.19 , pp. 927-932
    • Van de Putte, M.1    Wang, H.2    Chen, F.3    De Witte, P.A.4    Ni, Y.5
  • 116
    • 43849086304 scopus 로고    scopus 로고
    • Exploration of the mechanism underlying the tumor necrosis avidity of hypericin
    • Van de Putte M, Ni Y, De Witte PA. Exploration of the mechanism underlying the tumor necrosis avidity of hypericin. Oncol Rep. 2008; 19:921-6.
    • (2008) Oncol Rep , vol.19 , pp. 921-926
    • Van de Putte, M.1    Ni, Y.2    De Witte, P.A.3
  • 119
    • 84873902064 scopus 로고    scopus 로고
    • Transbilayer phospholipids molecular imaging
    • Belhocine TZ, Prato FS. Transbilayer phospholipids molecular imaging. EJNMMI Res. 2011; 1:17.
    • (2011) EJNMMI Res , vol.1 , pp. 17
    • Belhocine, T.Z.1    Prato, F.S.2


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