Hypoxia promotes migration and induces CXCR4 expression via HIF-1α activation in human osteosarcoma

PLoS ONE

Volumn 9, Issue 3, 2014, Pages

  Guo, Mingjun ^a   Cai, Chengkui ^a   Zhao, Guangyi ^b   Qiu, Xiuchun ^a   Zhao, Haien ^a   Ma, Qiong ^a   Tian, Liying ^a   Li, Xuelian ^c   Hu, Yunsheng ^a   Liao, Bo ^a   Ma, Baoan ^a   Fan, Qingyu ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b BETHUNE INTERNATIONAL PEACE HOSPITAL   (China)

^c Department of Surgery Xi'An Hospital of TCM   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR CXCR4; HYPOXIA INDUCIBLE FACTOR 1ALPHA; LUCIFERASE; MESSENGER RNA;

ARTICLE; CELL MIGRATION; CONTROLLED STUDY; HUMAN; HUMAN CELL; HUMAN TISSUE; HYPOXIA; IMMUNOCYTOCHEMISTRY; IMMUNOHISTOCHEMISTRY; OSTEOSARCOMA CELL; PROMOTER REGION; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; REPORTER GENE; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; TUMOR VOLUME; ADOLESCENT; ADULT; ANOXIA; CANCER STAGING; CELL HYPOXIA; CELL MOTION; FEMALE; GENE EXPRESSION REGULATION; GENETICS; MALE; METABOLISM; METASTASIS; MORTALITY; OSTEOSARCOMA; PATHOLOGY; TUMOR CELL LINE; YOUNG ADULT;

ADOLESCENT; ADULT; ANOXIA; CELL HYPOXIA; CELL LINE, TUMOR; CELL MOVEMENT; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MALE; NEOPLASM METASTASIS; NEOPLASM STAGING; OSTEOSARCOMA; RECEPTORS, CXCR4; TUMOR BURDEN; YOUNG ADULT;

EID: 84897473775     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0090518     Document Type: Article

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