-
1
-
-
0026639806
-
Angiogenesis
-
J. Folkman, and Y. Shing Angiogenesis J Biol Chem 267 1992 10931 10934
-
(1992)
J Biol Chem
, vol.267
, pp. 10931-10934
-
-
Folkman, J.1
Shing, Y.2
-
2
-
-
0034648765
-
Angiogenesis in cancer and other diseases
-
P. Carmeliet, and R.K. Jain Angiogenesis in cancer and other diseases Nature 407 2000 249 257
-
(2000)
Nature
, vol.407
, pp. 249-257
-
-
Carmeliet, P.1
Jain, R.K.2
-
3
-
-
0027033775
-
Inadequate vasculature in solid tumours: Consequences for cancer research strategies
-
J. Denekamp Inadequate vasculature in solid tumours: consequences for cancer research strategies Br J Radiol 24 1992 111 117
-
(1992)
Br J Radiol
, vol.24
, pp. 111-117
-
-
Denekamp, J.1
-
4
-
-
0032773566
-
Tumour vasculature as a target for cancer therapy
-
D.J. Chaplin, and G.J. Dougherty Tumour vasculature as a target for cancer therapy Br J Cancer 80 Suppl. 1 1999 57 64
-
(1999)
Br J Cancer
, vol.80
, Issue.1 SUPPL.
, pp. 57-64
-
-
Chaplin, D.J.1
Dougherty, G.J.2
-
5
-
-
2642571660
-
Vascular-targeting therapies for treatment of malignant disease
-
D.W. Siemann, D.J. Chaplin, and M.R. Horsman Vascular-targeting therapies for treatment of malignant disease Cancer 100 2004 2491 2499
-
(2004)
Cancer
, vol.100
, pp. 2491-2499
-
-
Siemann, D.W.1
Chaplin, D.J.2
Horsman, M.R.3
-
6
-
-
0030002174
-
Ablation of colorectal xenografts with combined radioimmunotherapy and tumour blood flow-modifying agents
-
R.B. Pedley, J.A. Boden, and R. Boden Ablation of colorectal xenografts with combined radioimmunotherapy and tumour blood flow-modifying agents Cancer Res 56 1996 3293 3300
-
(1996)
Cancer Res
, vol.56
, pp. 3293-3300
-
-
Pedley, R.B.1
Boden, J.A.2
Boden, R.3
-
7
-
-
0033567097
-
Enhancement of antibody-directed enzyme prodrug therapy in colorectal xenografts by an antivascular agent
-
R.B. Pedley, S.K. Sharma, and G.M. Boxer Enhancement of antibody-directed enzyme prodrug therapy in colorectal xenografts by an antivascular agent Cancer Res 59 1999 3998 4003
-
(1999)
Cancer Res
, vol.59
, pp. 3998-4003
-
-
Pedley, R.B.1
Sharma, S.K.2
Boxer, G.M.3
-
8
-
-
0037341637
-
Antivascular therapy of cancer: DMXAA
-
B.C. Baguley Antivascular therapy of cancer: DMXAA Lancet Oncol 4 2003 141 148
-
(2003)
Lancet Oncol
, vol.4
, pp. 141-148
-
-
Baguley, B.C.1
-
9
-
-
0036282385
-
The biology of the combretastatins as tumour vascular targeting agents
-
G.M. Tozer, C. Kanthou, and C.S. Parkins The biology of the combretastatins as tumour vascular targeting agents Int J Exp Pathol 83 2002 21 38
-
(2002)
Int J Exp Pathol
, vol.83
, pp. 21-38
-
-
Tozer, G.M.1
Kanthou, C.2
Parkins, C.S.3
-
10
-
-
1842607060
-
Combretastatin A4 phosphate
-
C.M. West, and P. Price Combretastatin A4 phosphate Anticancer Drugs 15 2004 179 187
-
(2004)
Anticancer Drugs
, vol.15
, pp. 179-187
-
-
West, C.M.1
Price, P.2
-
11
-
-
0024513175
-
Isolation and structure of the strong cell growth and tubulin inhibitor combretastatin A-4
-
G.R. Pettit, S.B. Singh, and E. Hamel Isolation and structure of the strong cell growth and tubulin inhibitor combretastatin A-4 Experientia 45 1989 209 211
-
(1989)
Experientia
, vol.45
, pp. 209-211
-
-
Pettit, G.R.1
Singh, S.B.2
Hamel, E.3
-
12
-
-
0030951899
-
Combretastatin A4, an agent that displays potent and selective toxicity toward tumour vasculature
-
G.G. Dark, S.A. Hill, and V.E. Prise Combretastatin A4, an agent that displays potent and selective toxicity toward tumour vasculature Cancer Res 57 1997 1829 1834
-
(1997)
Cancer Res
, vol.57
, pp. 1829-1834
-
-
Dark, G.G.1
Hill, S.A.2
Prise, V.E.3
-
13
-
-
0031742231
-
Targeting the tumour vasculature with combretastatin A-4 disodium phosphate: Effects on radiation therapy
-
L. Li, A. Rojiani, and D. Siemann Targeting the tumour vasculature with combretastatin A-4 disodium phosphate: effects on radiation therapy Int J Radiat Oncol Biol Phys 42 1998 899 903
-
(1998)
Int J Radiat Oncol Biol Phys
, vol.42
, pp. 899-903
-
-
Li, L.1
Rojiani, A.2
Siemann, D.3
-
14
-
-
0033119771
-
Combretastatin A-4 phosphate as a tumour vascular-targeting agent: Early effects in tumours and normal tissues
-
G.M. Tozer, V.E. Prise, and J. Wilson Combretastatin A-4 phosphate as a tumour vascular-targeting agent: early effects in tumours and normal tissues Cancer Res 59 1999 1626 1634
-
(1999)
Cancer Res
, vol.59
, pp. 1626-1634
-
-
Tozer, G.M.1
Prise, V.E.2
Wilson, J.3
-
15
-
-
0035064594
-
Effects of combretastatin A-4 phosphate on endothelial cell morphology in vitro and relationship to tumour vascular targeting activity in vivo
-
S.M. Galbraith, D.J. Chaplin, and F. Lee Effects of combretastatin A-4 phosphate on endothelial cell morphology in vitro and relationship to tumour vascular targeting activity in vivo Anticancer Res 21 2001 93 102
-
(2001)
Anticancer Res
, vol.21
, pp. 93-102
-
-
Galbraith, S.M.1
Chaplin, D.J.2
Lee, F.3
-
16
-
-
0036891440
-
Combination of vascular targeting agents with thermal or radiation therapy
-
M.R. Horsman, and R. Murata Combination of vascular targeting agents with thermal or radiation therapy Int J Radiat Oncol Biol Phys 54 2002 1518 1523
-
(2002)
Int J Radiat Oncol Biol Phys
, vol.54
, pp. 1518-1523
-
-
Horsman, M.R.1
Murata, R.2
-
17
-
-
0032950870
-
Anti-vascular approaches to solid tumour therapy: Evaluation of combretastatin A4 phosphate
-
D.J. Chaplin, G.R. Pettit, and S.A. Hill Anti-vascular approaches to solid tumour therapy: evaluation of combretastatin A4 phosphate Anticancer Res 19 1999 189 196
-
(1999)
Anticancer Res
, vol.19
, pp. 189-196
-
-
Chaplin, D.J.1
Pettit, G.R.2
Hill, S.A.3
-
18
-
-
0035889331
-
Combretastatin A-4 disodium phosphate: A vascular targeting agent that improves the anti-tumour effects of hyperthermia, radiation, and mild thermoradiotherapy
-
R. Murata, J. Overgaard, and M.R. Horsman Combretastatin A-4 disodium phosphate: a vascular targeting agent that improves the anti-tumour effects of hyperthermia, radiation, and mild thermoradiotherapy Int J Radiat Oncol Biol Phys 51 2001 1018 1024
-
(2001)
Int J Radiat Oncol Biol Phys
, vol.51
, pp. 1018-1024
-
-
Murata, R.1
Overgaard, J.2
Horsman, M.R.3
-
19
-
-
0035874889
-
Eradication of colorectal xenografts by combined radioimmunotherapy and combretastatin A4-phosphate
-
R.B. Pedley, S.A. Hill, and G.M. Boxer Eradication of colorectal xenografts by combined radioimmunotherapy and combretastatin A4-phosphate Cancer Res 61 2001 4716 4722
-
(2001)
Cancer Res
, vol.61
, pp. 4716-4722
-
-
Pedley, R.B.1
Hill, S.A.2
Boxer, G.M.3
-
20
-
-
0036891507
-
Synergy between vascular targeting agents and antibody-directed therapy
-
R.B. Pedley, E. El-Emir, and A.A. Flynn Synergy between vascular targeting agents and antibody-directed therapy Int J Radiat Oncol Biol Phys 54 2002 1524 1531
-
(2002)
Int J Radiat Oncol Biol Phys
, vol.54
, pp. 1524-1531
-
-
Pedley, R.B.1
El-Emir, E.2
Flynn, A.A.3
-
21
-
-
0037096814
-
A phase I pharmacokinetic and translational study of the novel vascular targeting agent combretastatin a-4 phosphate on a single-dose intravenous schedule in patients with advanced cancer
-
A. Dowlati, K. Robertson, and M. Cooney A phase I pharmacokinetic and translational study of the novel vascular targeting agent combretastatin a-4 phosphate on a single-dose intravenous schedule in patients with advanced cancer Cancer Res 62 2002 3408 3416
-
(2002)
Cancer Res
, vol.62
, pp. 3408-3416
-
-
Dowlati, A.1
Robertson, K.2
Cooney, M.3
-
22
-
-
0032758736
-
In vivo and in vitro evaluation of combretastatin A-4 and its sodium phosphate prodrug
-
K. Grosios, S.E. Holwell, and A.T. McGown In vivo and in vitro evaluation of combretastatin A-4 and its sodium phosphate prodrug Br J Cancer 81 1999 1318 1327
-
(1999)
Br J Cancer
, vol.81
, pp. 1318-1327
-
-
Grosios, K.1
Holwell, S.E.2
McGown, A.T.3
-
23
-
-
0031770618
-
The effects of combretastatin A-4 disodium phosphate in a C3H mouse mammary carcinoma and a variety of murine spontaneous tumours
-
M.R. Horsman, E. Ehrnrooth, and M. Ladekarl The effects of combretastatin A-4 disodium phosphate in a C3H mouse mammary carcinoma and a variety of murine spontaneous tumours Int J Radiat Oncol Biol Phys 42 1998 895 898
-
(1998)
Int J Radiat Oncol Biol Phys
, vol.42
, pp. 895-898
-
-
Horsman, M.R.1
Ehrnrooth, E.2
Ladekarl, M.3
-
24
-
-
0036891515
-
The development of combretastatin A4 phosphate as a vascular targeting agent
-
D.J. Chaplin, and S.A. Hill The development of combretastatin A4 phosphate as a vascular targeting agent Int J Radiat Oncol Biol Phys 54 2002 1491 1496
-
(2002)
Int J Radiat Oncol Biol Phys
, vol.54
, pp. 1491-1496
-
-
Chaplin, D.J.1
Hill, S.A.2
-
25
-
-
0033844886
-
Combretastatin A-4 prodrug: A potent inhibitor of malignant hemangioendothelioma cell proliferation
-
A.S. Bohle, I. Leuschner, and H. Kalthoff Combretastatin A-4 prodrug: a potent inhibitor of malignant hemangioendothelioma cell proliferation Int J Cancer 87 2000 838 843
-
(2000)
Int J Cancer
, vol.87
, pp. 838-843
-
-
Bohle, A.S.1
Leuschner, I.2
Kalthoff, H.3
-
26
-
-
0032532391
-
Induction of apoptosis in proliferating human endothelial cells by the tumour-specific antiangiogenesis agent combretastatin A-4
-
S. Iyer, D.J. Chaplin, and D.S. Rosenthal Induction of apoptosis in proliferating human endothelial cells by the tumour-specific antiangiogenesis agent combretastatin A-4 Cancer Res 58 1998 4510 4514
-
(1998)
Cancer Res
, vol.58
, pp. 4510-4514
-
-
Iyer, S.1
Chaplin, D.J.2
Rosenthal, D.S.3
-
27
-
-
3843090808
-
Combretastatin family member OXI4503 induces tumor vascular collapse through the induction of endothelial apoptosis
-
Y. Sheng, J. Hua, and K.G. Pinney Combretastatin family member OXI4503 induces tumor vascular collapse through the induction of endothelial apoptosis Int J Cancer 111 2004 604 610
-
(2004)
Int J Cancer
, vol.111
, pp. 604-610
-
-
Sheng, Y.1
Hua, J.2
Pinney, K.G.3
-
28
-
-
0034906627
-
Combretastatin A4 prodrug study of effect on the growth and the microvasculature of colorectal liver metastases in a murine model
-
C. Malcontenti-Wilson, V. Muralidharan, and S. Skinner Combretastatin A4 prodrug study of effect on the growth and the microvasculature of colorectal liver metastases in a murine model Clin Cancer Res 7 2001 1052 1060
-
(2001)
Clin Cancer Res
, vol.7
, pp. 1052-1060
-
-
Malcontenti-Wilson, C.1
Muralidharan, V.2
Skinner, S.3
-
29
-
-
0036278972
-
Antitumour activity of the novel vascular targeting agent ZD6126 in a panel of tumour models
-
D.C. Blakey, F.R. Westwood, and M. Walker Antitumour activity of the novel vascular targeting agent ZD6126 in a panel of tumour models Clin Cancer Res 8 2002 1974 1983
-
(2002)
Clin Cancer Res
, vol.8
, pp. 1974-1983
-
-
Blakey, D.C.1
Westwood, F.R.2
Walker, M.3
-
30
-
-
0036200834
-
Differential sensitivity of two adenocarcinoma xenografts to the anti-vascular drugs combretastatin A4 phosphate and 5,6-dimethylxanthenone-4- acetic acid, assessed using MRI and MRS
-
D.A. Beauregard, R.B. Pedley, and S.A. Hill Differential sensitivity of two adenocarcinoma xenografts to the anti-vascular drugs combretastatin A4 phosphate and 5,6-dimethylxanthenone-4-acetic acid, assessed using MRI and MRS NMR Biomed 15 2002 99 105
-
(2002)
NMR Biomed
, vol.15
, pp. 99-105
-
-
Beauregard, D.A.1
Pedley, R.B.2
Hill, S.A.3
-
31
-
-
0036197311
-
Evaluation of the anti-vascular effects of combretastatin in rodent tumours by dynamic contrast enhanced MRI
-
R.J. Maxwell, J. Wilson, and V.E. Prise Evaluation of the anti-vascular effects of combretastatin in rodent tumours by dynamic contrast enhanced MRI NMR Biomed 15 2002 89 98
-
(2002)
NMR Biomed
, vol.15
, pp. 89-98
-
-
Maxwell, R.J.1
Wilson, J.2
Prise, V.E.3
-
32
-
-
0029150035
-
Application of an image analysis system to the quantification of tumour perfusion and vascularity in human glioma xenografts
-
P.F. Rijkin, H.J. Bernsen, and A.J. van der Kogel Application of an image analysis system to the quantification of tumour perfusion and vascularity in human glioma xenografts Microvasc. Res. 50 1995 141 153
-
(1995)
Microvasc. Res.
, vol.50
, pp. 141-153
-
-
Rijkin, P.F.1
Bernsen, H.J.2
Van Der Kogel, A.J.3
-
33
-
-
0032944785
-
Vascular architecture and microenvironmental parameters in human squamous cell carcinoma xenografts: Effects of carbogen and nicotinamide
-
J. Bussink, J.H. Kaanders, and P.F. Rijken Vascular architecture and microenvironmental parameters in human squamous cell carcinoma xenografts: effects of carbogen and nicotinamide Radiother Oncol 50 1999 173 184
-
(1999)
Radiother Oncol
, vol.50
, pp. 173-184
-
-
Bussink, J.1
Kaanders, J.H.2
Rijken, P.F.3
-
34
-
-
0034265986
-
Spatial relationship between hypoxia and the (perfused) vascular network in human glioma xenografts: A quantitative multi-parameter analysis
-
P.F. Rijken, H.J. Bernsen, and J.P. Peters Spatial relationship between hypoxia and the (perfused) vascular network in human glioma xenografts: a quantitative multi-parameter analysis Int J Radiat Oncol Biol Phys 48 2000 571 582
-
(2000)
Int J Radiat Oncol Biol Phys
, vol.48
, pp. 571-582
-
-
Rijken, P.F.1
Bernsen, H.J.2
Peters, J.P.3
-
35
-
-
0036716726
-
Vascular architecture, hypoxia, and proliferation in first-generation xenografts of human head-and-neck squamous cell carcinoma
-
A.S. Ljungkvist, J. Bussink, and P.F. Rijken Vascular architecture, hypoxia, and proliferation in first-generation xenografts of human head-and-neck squamous cell carcinoma Int J Radiat Oncol Biol Phys 54 2002 215 228
-
(2002)
Int J Radiat Oncol Biol Phys
, vol.54
, pp. 215-228
-
-
Ljungkvist, A.S.1
Bussink, J.2
Rijken, P.F.3
|