-
1
-
-
0036278972
-
Antitumor activity of the novel vascular targeting-agent ZD6126 in a panel of tumor models
-
Blakey DC, Westwood FR, Walker M, et al. Antitumor activity of the novel vascular targeting-agent ZD6126 in a panel of tumor models. Clin Cancer Res 2002;8:1974-83.
-
(2002)
Clin. Cancer Res.
, vol.8
, pp. 1974-1983
-
-
Blakey, D.C.1
Westwood, F.R.2
Walker, M.3
-
2
-
-
0036569804
-
Enhancement of radiation therapy by the novel vascular targeting agent ZD6126
-
Siemann DW, Rojiani AM. Enhancement of radiation therapy by the novel vascular targeting agent ZD6126. Int J Radiat Oncol Biol Phys 2002; 53:164-71.
-
(2002)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.53
, pp. 164-171
-
-
Siemann, D.W.1
Rojiani, A.M.2
-
3
-
-
14444288522
-
The enhanced tumorigenic activity of a mutant epidermal growth factor receptor common in human cancers is mediated by threshold levels of constitutive tyrosine phosphorylation and unattenuated signaling
-
Su Hang HJ, Nagane M, Klingbeil CK, et al. The enhanced tumorigenic activity of a mutant epidermal growth factor receptor common in human cancers is mediated by threshold levels of constitutive tyrosine phosphorylation and unattenuated signaling. J Biol Chem 1997;272:2927-35.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 2927-2935
-
-
Su Hang, H.J.1
Nagane, M.2
Klingbeil, C.K.3
-
4
-
-
0031409362
-
Epidermal growth factor receptor inhibition by a monoclonal antibody as anticancer therapy
-
Mendelsohn J. Epidermal growth factor receptor inhibition by a monoclonal antibody as anticancer therapy. Clin Cancer Res 1997;3:2703-7.
-
(1997)
Clin. Cancer Res.
, vol.3
, pp. 2703-2707
-
-
Mendelsohn, J.1
-
5
-
-
0034084314
-
Modulation of radiation response after epidermal growth factor receptor blockade in squamous cell carcinomas: Inhibition of damage repair, cell cycle kinetics, and tumor angiogenesis
-
Huang SM, Harari PM. Modulation of radiation response after epidermal growth factor receptor blockade in squamous cell carcinomas: inhibition of damage repair, cell cycle kinetics, and tumor angiogenesis. Clin Cancer Res 2000;6:2166-74.
-
(2000)
Clin. Cancer Res.
, vol.6
, pp. 2166-2174
-
-
Huang, S.M.1
Harari, P.M.2
-
6
-
-
0034068319
-
Antitumor effects and potentiation of cytotoxic drugs activity in human cancer cells by ZD1839 (Iressa), and epidermal growth factor receptor tyrosine kinase inhibitor
-
Ciardiello F, Caputo R, Bianco R, et al. Antitumor effects and potentiation of cytotoxic drugs activity in human cancer cells by ZD1839 (Iressa), and epidermal growth factor receptor tyrosine kinase inhibitor. Clin Cancer Res 2000;6:2053-63.
-
(2000)
Clin. Cancer Res.
, vol.6
, pp. 2053-2063
-
-
Ciardiello, F.1
Caputo, R.2
Bianco, R.3
-
7
-
-
0034489914
-
Efficacy of cytotoxic agents against human tumor xenografts is markedly enhanced by coadministration of ZD1839 (Iressa), an inhibitor of EGFR tyrosine kinase
-
Sirotnak F, Zakowski M, Miller V, et al. Efficacy of cytotoxic agents against human tumor xenografts is markedly enhanced by coadministration of ZD1839 (Iressa), an inhibitor of EGFR tyrosine kinase. Clin Cancer Res 2000;6:4885-92.
-
(2000)
Clin. Cancer Res.
, vol.6
, pp. 4885-4892
-
-
Sirotnak, F.1
Zakowski, M.2
Miller, V.3
-
8
-
-
0036005846
-
ZD1839, a selective epidermal growth factor receptor tyrosine kinase inhibitor, alone and in combination with radiation and chemotherapy as a new therapeutic strategy in on-small cell lung cancer
-
Raben D, Helfrich BA, Chan D, et al. ZD1839, a selective epidermal growth factor receptor tyrosine kinase inhibitor, alone and in combination with radiation and chemotherapy as a new therapeutic strategy in on-small cell lung cancer. Semin Oncol 2002;29:37-46.
-
(2002)
Semin. Oncol.
, vol.29
, pp. 37-46
-
-
Raben, D.1
Helfrich, B.A.2
Chan, D.3
-
9
-
-
0036795061
-
Enhancement of antitumor activity of ionizing radiation by combined treatment with the selective epidermal growth factor receptor-tyrosine kinase inhibitor ZD1839 (Iressa)
-
Bianco C, Tortora G, Bianco R, et al. Enhancement of antitumor activity of ionizing radiation by combined treatment with the selective epidermal growth factor receptor-tyrosine kinase inhibitor ZD1839 (Iressa). Clin Cancer Res 2002;8:3250-8.
-
(2002)
Clin. Cancer Res.
, vol.8
, pp. 3250-3258
-
-
Bianco, C.1
Tortora, G.2
Bianco, R.3
-
10
-
-
0036681995
-
Modulation of radiation response and tumor-induced angiogenesis after epidermal growth factor receptor inhibition by ZD1839 (Iressa)
-
Huang SM, Li J, Armstrong EA, Harari PM. Modulation of radiation response and tumor-induced angiogenesis after epidermal growth factor receptor inhibition by ZD1839 (Iressa). Cancer Res 2002;62:4300-6.
-
(2002)
Cancer Res.
, vol.62
, pp. 4300-7306
-
-
Huang, S.M.1
Li, J.2
Armstrong, E.A.3
Harari, P.M.4
-
11
-
-
0032815618
-
Radiation-induced release of transforming growth factor α activates the epidermal growth factor receptor and mitogen-activated protein kinase pathway in carcinoma cells, leading to increased proliferation and protection from radiation-induced cell death
-
Dent P, Reardon DB, Park JS, et al. Radiation-induced release of transforming growth factor α activates the epidermal growth factor receptor and mitogen-activated protein kinase pathway in carcinoma cells, leading to increased proliferation and protection from radiation-induced cell death. Mol Biol Cell 1999;10:2493-506.
-
(1999)
Mol. Biol. Cell.
, vol.10
, pp. 2493-2506
-
-
Dent, P.1
Reardon, D.B.2
Park, J.S.3
-
12
-
-
0032719534
-
Inverse relationship between epidermal growth factor receptor expression and radiocurability of murine carcinomas
-
Akimoto T, Hunter NR, Buchmiller L, Mason K, Ang KK, Milas L. Inverse relationship between epidermal growth factor receptor expression and radiocurability of murine carcinomas. Clin Cancer Res 1999;5: 2884-90.
-
(1999)
Clin. Cancer Res.
, vol.5
, pp. 2884-2890
-
-
Akimoto, T.1
Hunter, N.R.2
Buchmiller, L.3
Mason, K.4
Ang, K.K.5
Milas, L.6
-
13
-
-
0347928791
-
EGFR blockade with ZD1839 ("Iressa") potentiates the antitumor effects of single and multiple fractions of ionizing radiation in human A431 squamous cell carcinoma
-
Solomon B, Hagekyriakou J, Trivett MK, Stacker SA, McArthur GA, Gullinane C. EGFR blockade with ZD1839 ("Iressa") potentiates the antitumor effects of single and multiple fractions of ionizing radiation in human A431 squamous cell carcinoma. Int J Radiat Oncol Biol Phys 2003; 55:713-23.
-
(2003)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.55
, pp. 713-723
-
-
Solomon, B.1
Hagekyriakou, J.2
Trivett, M.K.3
Stacker, S.A.4
McArthur, G.A.5
Gullinane, C.6
-
14
-
-
0013840905
-
Tumor anoxia and the response to radiation
-
Thomlinson J. Tumor anoxia and the response to radiation. Sci Basis Med Annu Rev 1965;74-90.
-
(1965)
Sci. Basis Med. Annu. Rev.
, pp. 74-90
-
-
Thomlinson, J.1
-
15
-
-
0003313092
-
Phase III comparison of sequential vs. concurrent chemoradiation for patients with unresected stage III non-small cell lung cancer (NSCLC): Initial report of Radiation Therapy Oncology Group (RTOG) 9410
-
[abstract]
-
Curran WJ, Scott C, Langer C, et al. Phase III comparison of sequential vs. concurrent chemoradiation for patients with unresected stage III non-small cell lung cancer (NSCLC): initial report of Radiation Therapy Oncology Group (RTOG) 9410 [abstract]. Proc Am Soc Clin Oncol 2000;19:484A.
-
(2000)
Proc. Am. Soc. Clin. Oncol.
, vol.19
-
-
Curran, W.J.1
Scott, C.2
Langer, C.3
-
16
-
-
0037115398
-
ZD6126: A novel vascular-targeting agent that causes selective destruction of tumor vasculature
-
Davis PD, Dougherty GJ, Blakey DC, et al. ZD6126: a novel vascular-targeting agent that causes selective destruction of tumor vasculature. Cancer Res 2002;62:7247-53.
-
(2002)
Cancer Res.
, vol.62
, pp. 7247-7253
-
-
Davis, P.D.1
Dougherty, G.J.2
Blakey, D.C.3
-
17
-
-
0001303063
-
A phase II trial of ZD1839 ("Iressa") in advanced non-small cell lung cancer (NSCLC) patients who had failed platinum- and docetaxel-based regimens (IDEAL 2)
-
abstract 1166
-
Kris M, Natale RB, Herbst R, et al. A phase II trial of ZD1839 ("Iressa") in advanced non-small cell lung cancer (NSCLC) patients who had failed platinum- and docetaxel-based regimens (IDEAL 2). Proc Am Soc Clin Oncol 2002;21:292a, abstract 1166.
-
(2002)
Proc. Am. Soc. Clin. Oncol.
, vol.21
-
-
Kris, M.1
Natale, R.B.2
Herbst, R.3
-
18
-
-
0012381722
-
Multi-institutional randomized phase II trial of gefitinib for previously treated patients with advanced non-small-cell lung cancer
-
Fukuoka K, Yano S, Giaccone G, et al. Multi-institutional randomized phase II trial of gefitinib for previously treated patients with advanced non-small-cell lung cancer. J Clin Oncol 2003;21:2237-46.
-
(2003)
J. Clin. Oncol.
, vol.21
, pp. 2237-2246
-
-
Fukuoka, K.1
Yano, S.2
Giaccone, G.3
-
19
-
-
0242668485
-
Tumor EGFR membrane staining is not clinically relevant for predicting response in patients receiving gefitinib ("Iressa," ZD1839) monotherapy for pretreated advanced non-small-cell lung cancer: IDEAL 1 and 2
-
2nd ed
-
Bailey LR, Kris M, Wolf M, et al. Tumor EGFR membrane staining is not clinically relevant for predicting response in patients receiving gefitinib ("Iressa," ZD1839) monotherapy for pretreated advanced non-small-cell lung cancer: IDEAL 1 and 2. 2nd ed. Proc Am Assoc Cancer Res 2003:44.
-
(2003)
Proc. Am. Assoc. Cancer Res.
, pp. 44
-
-
Bailey, L.R.1
Kris, M.2
Wolf, M.3
-
20
-
-
0035394833
-
Acquired resistance to the antitumor effect of epidermal growth factor receptor-blocking antibodies in vitro: A role for altered tumor angiogenesis
-
Viloria-Petit A, Crombet T, Jothy S, et al. Acquired resistance to the antitumor effect of epidermal growth factor receptor-blocking antibodies in vitro: a role for altered tumor angiogenesis. Cancer Res 2001;61: 5090-101.
-
(2001)
Cancer Res.
, vol.61
, pp. 5090-5101
-
-
Viloria-Petit, A.1
Crombet, T.2
Jothy, S.3
-
21
-
-
0036141447
-
Insulin-like growth factor receptor I mediates resistance to anti-epidermal growth factor receptor therapy in primary human glioblastoma cells through continued activation of phosphoinositide 3-kinase signaling
-
Chakravarti A, Loefler JS, Dyson NJ. Insulin-like growth factor receptor I mediates resistance to anti-epidermal growth factor receptor therapy in primary human glioblastoma cells through continued activation of phosphoinositide 3-kinase signaling. Cancer Res 2002;62:200-7.
-
(2002)
Cancer Res.
, vol.62
, pp. 200-207
-
-
Chakravarti, A.1
Loefler, J.S.2
Dyson, N.J.3
-
22
-
-
0032527802
-
Cooperative inhibition of renal cancer growth by anti-epidermal growth factor receptor antibody and protein kinase A antisense oligonucleotide
-
Ciardiello F, Caputo R, Bianco R, et al. Cooperative inhibition of renal cancer growth by anti-epidermal growth factor receptor antibody and protein kinase A antisense oligonucleotide. J Natl Cancer Inst 1998;90: 1087-94.
-
(1998)
J. Natl. Cancer Inst.
, vol.90
, pp. 1087-1094
-
-
Ciardiello, F.1
Caputo, R.2
Bianco, R.3
-
23
-
-
0033818695
-
Antiangiogenic and antitumor activity of anti-epidermal growth factor receptor C225 monoclonal antibody in combination with vascular endothelial growth factor antisense oligonucleotide in human GEO colon cancer cells
-
Ciardiello F, Bianco R, Damiano V, et al. Antiangiogenic and antitumor activity of anti-epidermal growth factor receptor C225 monoclonal antibody in combination with vascular endothelial growth factor antisense oligonucleotide in human GEO colon cancer cells. Clin Cancer Res 2000;6:3739-47.
-
(2000)
Clin. Cancer Res.
, vol.6
, pp. 3739-3747
-
-
Ciardiello, F.1
Bianco, R.2
Damiano, V.3
-
24
-
-
0036225446
-
Cooperative inhibitory effect of ZD1 839 (Iressa) in combination with trastuzumab (Herceptin) on human breast cancer cell growth
-
Normanno N, Campiglio M, De LA, et al. Cooperative inhibitory effect of ZD1 839 (Iressa) in combination with trastuzumab (Herceptin) on human breast cancer cell growth. Ann Oncol 2002; 13:65-72.
-
(2002)
Ann. Oncol.
, vol.13
, pp. 65-72
-
-
Normanno, N.1
Campiglio, M.2
De, L.A.3
-
25
-
-
0036531923
-
Blockade of vascular endothelial growth factor receptor and epidermal growth factor receptor signaling for therapy of metastatic human pancreatic cancer
-
Apr 1
-
Baker CH, Solorzano CC, Fidler U. Blockade of vascular endothelial growth factor receptor and epidermal growth factor receptor signaling for therapy of metastatic human pancreatic cancer. Cancer Res 2002 Apr 1; 62:1996-2003.
-
(2002)
Cancer Res.
, vol.62
, pp. 1996-2003
-
-
Baker, C.H.1
Solorzano, C.C.2
Fidler, U.3
|