메뉴 건너뛰기




Volumn 11, Issue 9, 2005, Pages 3514-3522

Differential effects of vascular endothelial growth factor receptor-2 inhibitor ZD6474 on circulating endothelial progenitors and mature circulating endothelial cells: Implications for use as a surrogate marker of antiangiogenic activity

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOGENESIS INHIBITOR; BEVACIZUMAB; BIOCHEMICAL MARKER; MONOCLONAL ANTIBODY; N ACETYLCOLCHINOL PHOSPHATE; VANDETANIB; VASCULOTROPIN RECEPTOR 1; VASCULOTROPIN RECEPTOR 2;

EID: 20944436688     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-04-2271     Document Type: Article
Times cited : (161)

References (49)
  • 1
    • 85013312416 scopus 로고
    • Tumor angiogenesis: Therapeutic implications
    • Folkman J. Tumor angiogenesis: therapeutic implications. N Engl J Med 1971;285:1182-6.
    • (1971) N Engl J Med , vol.285 , pp. 1182-1186
    • Folkman, J.1
  • 2
    • 2542561964 scopus 로고    scopus 로고
    • Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer
    • Hurwitz H, Fehrenbacher L, Novotny W, et al. Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer. N Engl J Med 2004; 350:2335-42.
    • (2004) N Engl J Med , vol.350 , pp. 2335-2342
    • Hurwitz, H.1    Fehrenbacher, L.2    Novotny, W.3
  • 3
    • 0042343801 scopus 로고    scopus 로고
    • A randomized trial of bevacizumab, an anti-vascular endothelial growth factor antibody, for metastatic renal cancer
    • Yang JC, Haworth L, Sherry RM, et al. A randomized trial of bevacizumab, an anti-vascular endothelial growth factor antibody, for metastatic renal cancer. N Engl J Med 2003;349:427-34.
    • (2003) N Engl J Med , vol.349 , pp. 427-434
    • Yang, J.C.1    Haworth, L.2    Sherry, R.M.3
  • 4
    • 2942657615 scopus 로고    scopus 로고
    • Randomized phase II trial comparing bevacizumab plus carboplatin and paclitaxel with carboplatin and paclitaxel alone in previously untreated locally advanced or metastatic non-small-cell lung cancer
    • Johnson DH, Fehrenbacher L, Novotny WF, et al. Randomized phase II trial comparing bevacizumab plus carboplatin and paclitaxel with carboplatin and paclitaxel alone in previously untreated locally advanced or metastatic non-small-cell lung cancer. J Clin Oncol 2004;22:2184-91.
    • (2004) J Clin Oncol , vol.22 , pp. 2184-2191
    • Johnson, D.H.1    Fehrenbacher, L.2    Novotny, W.F.3
  • 6
    • 0037106384 scopus 로고    scopus 로고
    • Development of biologic markers of response and assessment of antiangiogenic activity in a clinical trial of human recombinant endostatin
    • Herbst RS, Mullani NA, Davis DW, et al. Development of biologic markers of response and assessment of antiangiogenic activity in a clinical trial of human recombinant endostatin. J Clin Oncol 2002;20: 3804-14.
    • (2002) J Clin Oncol , vol.20 , pp. 3804-3814
    • Herbst, R.S.1    Mullani, N.A.2    Davis, D.W.3
  • 7
    • 4444250452 scopus 로고    scopus 로고
    • Phase II study of the antiangiogenic agent SU5416 in patients with advanced soft tissue sarcomas
    • Heymach JV, Desai J, Manola J, et al. Phase II study of the antiangiogenic agent SU5416 in patients with advanced soft tissue sarcomas. Clin Cancer Res 2004; 10:5732-40.
    • (2004) Clin Cancer Res , vol.10 , pp. 5732-5740
    • Heymach, J.V.1    Desai, J.2    Manola, J.3
  • 8
    • 0035383784 scopus 로고    scopus 로고
    • Resting and activated endothelial cells are increased in the peripheral blood of cancer patients
    • Mancuso P, Burlini A, Pruneri G, Goldhirsch A, Martinelli G, Bertolini F. Resting and activated endothelial cells are increased in the peripheral blood of cancer patients. Blood 2001;97:3658-61.
    • (2001) Blood , vol.97 , pp. 3658-3661
    • Mancuso, P.1    Burlini, A.2    Pruneri, G.3    Goldhirsch, A.4    Martinelli, G.5    Bertolini, F.6
  • 9
    • 0942277099 scopus 로고    scopus 로고
    • Increased levels of viable circulating endothelial cells are an indicator of progressive disease in cancer patients
    • Beerepoot LV, Mehra N, Vermaat JS, Zonnenberg BA, Gebbink MF, Voest EE. Increased levels of viable circulating endothelial cells are an indicator of progressive disease in cancer patients. Ann Oncol 2004;15:139-45.
    • (2004) Ann Oncol , vol.15 , pp. 139-145
    • Beerepoot, L.V.1    Mehra, N.2    Vermaat, J.S.3    Zonnenberg, B.A.4    Gebbink, M.F.5    Voest, E.E.6
  • 10
    • 0032945433 scopus 로고    scopus 로고
    • Ischemia- and cytokine-induced mobilization of bone marrow-derived endothelial progenitor cells for neovascularization
    • Takahashi T, Kalka C, Masuda H, et al. Ischemia- and cytokine-induced mobilization of bone marrow-derived endothelial progenitor cells for neovascularization. Nat Med 1999;5:434-8.
    • (1999) Nat Med , vol.5 , pp. 434-438
    • Takahashi, T.1    Kalka, C.2    Masuda, H.3
  • 11
    • 0033565540 scopus 로고    scopus 로고
    • VEGF contributes to postnatal neovascularization by mobilizing bone marrow-derived endothelial progenitor cells
    • Asahara T, Takahashi T, Masuda H, et al. VEGF contributes to postnatal neovascularization by mobilizing bone marrow-derived endothelial progenitor cells. EMBO J 1999;18:3964-72.
    • (1999) EMBO J , vol.18 , pp. 3964-3972
    • Asahara, T.1    Takahashi, T.2    Masuda, H.3
  • 12
    • 0034705367 scopus 로고    scopus 로고
    • Vascular endothelial growth factor (165) gene transfer augments circulating endothelial progenitor cells in human subjects
    • Kalka C, Masuda H, Takahashi T, et al. Vascular endothelial growth factor (165) gene transfer augments circulating endothelial progenitor cells in human subjects. Circ Res 2000;86:1198-202.
    • (2000) Circ Res , vol.86 , pp. 1198-1202
    • Kalka, C.1    Masuda, H.2    Takahashi, T.3
  • 13
    • 0033802672 scopus 로고    scopus 로고
    • VEGF gene transfer mobilizes endothelial progenitor cells in patients with inoperable coronary disease
    • Kalka C, Tehrani H, Laudenberg B, et al. VEGF gene transfer mobilizes endothelial progenitor cells in patients with inoperable coronary disease. Ann Thorac Surg 2000;70:829-34.
    • (2000) Ann Thorac Surg , vol.70 , pp. 829-834
    • Kalka, C.1    Tehrani, H.2    Laudenberg, B.3
  • 14
    • 12944253116 scopus 로고    scopus 로고
    • Expression of VEGFR-2 and AC133 by circulating human CD34(+) cells identifies a population of functional endothelial precursors
    • Peichev M, Naiyer AJ, Pereira D, et al. Expression of VEGFR-2 and AC133 by circulating human CD34(+) cells identifies a population of functional endothelial precursors. Blood 2000;95:952-8.
    • (2000) Blood , vol.95 , pp. 952-958
    • Peichev, M.1    Naiyer, A.J.2    Pereira, D.3
  • 16
    • 0037452135 scopus 로고    scopus 로고
    • Circulating endothelial cells as markers for ANCA-associated small-vessel vasculitis
    • Woywodt A, Streiber F, de Groot K, Regeisberger H, Haller H, Haubitz M. Circulating endothelial cells as markers for ANCA-associated small-vessel vasculitis. Lancet 2003;361:206-10.
    • (2003) Lancet , vol.361 , pp. 206-210
    • Woywodt, A.1    Streiber, F.2    De Groot, K.3    Regeisberger, H.4    Haller, H.5    Haubitz, M.6
  • 17
    • 0027360146 scopus 로고
    • Demonstration of Rickettsia conorii-induced endothelial injury in vivo by measuring circulating endothelial cells, thrombomodulin, and von Willebrand factor in patients with Mediterranean spotted fever
    • George F, Brouqui P, Boffa MC, et al. Demonstration of Rickettsia conorii-induced endothelial injury in vivo by measuring circulating endothelial cells, thrombomodulin, and von Willebrand factor in patients with Mediterranean spotted fever. Blood 1993;82:2109-16.
    • (1993) Blood , vol.82 , pp. 2109-2116
    • George, F.1    Brouqui, P.2    Boffa, M.C.3
  • 18
    • 0035148874 scopus 로고    scopus 로고
    • Circulating endothelial cells in patients with septic shock
    • Mutunga M, Fulton B, Bullock R, et al. Circulating endothelial cells in patients with septic shock. Am J Respir Crit Care Med 2001;163:195-200.
    • (2001) Am J Respir Crit Care Med , vol.163 , pp. 195-200
    • Mutunga, M.1    Fulton, B.2    Bullock, R.3
  • 19
    • 0033135720 scopus 로고    scopus 로고
    • Direct evidence of endothelial injury in acute myocardial infarction and unstable angina by demonstration of circulating endothelial cells
    • Mutin M, Canavy I, Blann A, Bory M, Sampol J, Dignat-George F. Direct evidence of endothelial injury in acute myocardial infarction and unstable angina by demonstration of circulating endothelial cells. Blood 1999;93:2951-8.
    • (1999) Blood , vol.93 , pp. 2951-2958
    • Mutin, M.1    Canavy, I.2    Blann, A.3    Bory, M.4    Sampol, J.5    Dignat-George, F.6
  • 21
    • 0041358457 scopus 로고    scopus 로고
    • + stem cells play a key role in therapeutic angiogenesis induced by bone marrow cell implantation
    • + stem cells play a key role in therapeutic angiogenesis induced by bone marrow cell implantation. Am J Physiol Heart Circ Physiol 2003;285:H931-7.
    • (2003) Am J Physiol Heart Circ Physiol , vol.285
    • Li, T.S.1    Hamano, K.2    Nishida, M.3
  • 22
    • 0035893252 scopus 로고    scopus 로고
    • Analysis of lung tumor initiation and progression using conditional expression of oncogenic K-ras
    • Jackson EL, Willis N, Mercer K, et al. Analysis of lung tumor initiation and progression using conditional expression of oncogenic K-ras. Genes Dev 2001; 15:3243-8.
    • (2001) Genes Dev , vol.15 , pp. 3243-3248
    • Jackson, E.L.1    Willis, N.2    Mercer, K.3
  • 23
    • 0037529332 scopus 로고    scopus 로고
    • Multistep nature of microvascular recruitment of ex vivo-expanded embryonic endothelial progenitor cells during tumor angiogenesis
    • Vajkoczy P, Blum S, Lamparter M, et al. Multistep nature of microvascular recruitment of ex vivo-expanded embryonic endothelial progenitor cells during tumor angiogenesis. J Exp Med 2003;197:1755-65.
    • (2003) J Exp Med , vol.197 , pp. 1755-1765
    • Vajkoczy, P.1    Blum, S.2    Lamparter, M.3
  • 24
    • 0742324490 scopus 로고    scopus 로고
    • Hematopoietic stem cells and endothelial cell precursors express Tie-2, CD31 and CD45
    • Shaw JP, Basch R, Shamamian P. Hematopoietic stem cells and endothelial cell precursors express Tie-2, CD31 and CD45. Blood Cells Mol Dis 2004; 32:168-75.
    • (2004) Blood Cells Mol Dis , vol.32 , pp. 168-175
    • Shaw, J.P.1    Basch, R.2    Shamamian, P.3
  • 25
    • 7244242362 scopus 로고    scopus 로고
    • Identification of a novel hierarchy of endothelial progenitor cells using human peripheral and umbilical cord blood
    • Ingram DA, Mead LE, Tanaka H, et al. Identification of a novel hierarchy of endothelial progenitor cells using human peripheral and umbilical cord blood. Blood 2004;104:2752-60.
    • (2004) Blood , vol.104 , pp. 2752-2760
    • Ingram, D.A.1    Mead, L.E.2    Tanaka, H.3
  • 26
    • 0035360833 scopus 로고    scopus 로고
    • Kinetics and viability of circulating endothelial cells as surrogate angiogenesis marker in an animal model of human lymphoma
    • Monestiroli S, Mancuso P, Burlini A, et al. Kinetics and viability of circulating endothelial cells as surrogate angiogenesis marker in an animal model of human lymphoma. Cancer Res 2001;61:4341-4.
    • (2001) Cancer Res , vol.61 , pp. 4341-4344
    • Monestiroli, S.1    Mancuso, P.2    Burlini, A.3
  • 27
    • 0346365369 scopus 로고    scopus 로고
    • Endostatin inhibits the vascular endothelial growth factor-induced mobilization of endothelial progenitor cells
    • Schuch G, Heymach JV, Nomi M, et al. Endostatin inhibits the vascular endothelial growth factor-induced mobilization of endothelial progenitor cells. Cancer Res 2003;63:8345-50.
    • (2003) Cancer Res , vol.63 , pp. 8345-8350
    • Schuch, G.1    Heymach, J.V.2    Nomi, M.3
  • 28
    • 12244271051 scopus 로고    scopus 로고
    • Continuous infusion of endostatin inhibits differentiation, mobilization, and clonogenic potential of endothelial cell progenitors
    • Capillo M, Mancuso P, Gobbi A, et al. Continuous infusion of endostatin inhibits differentiation, mobilization, and clonogenic potential of endothelial cell progenitors. Clin Cancer Res 2003;9:377-82.
    • (2003) Clin Cancer Res , vol.9 , pp. 377-382
    • Capillo, M.1    Mancuso, P.2    Gobbi, A.3
  • 29
    • 0041589524 scopus 로고    scopus 로고
    • Maximum tolerable dose and low-dose metronomic chemotherapy have opposite effects on the mobilization and viability of circulating endothelial progenitor cells
    • Bertolini F, Paul S, Mancuso P, et al. Maximum tolerable dose and low-dose metronomic chemotherapy have opposite effects on the mobilization and viability of circulating endothelial progenitor cells. Cancer Res 2003;63:4342-6.
    • (2003) Cancer Res , vol.63 , pp. 4342-4346
    • Bertolini, F.1    Paul, S.2    Mancuso, P.3
  • 30
    • 1042307662 scopus 로고    scopus 로고
    • Circulating endothelial cells as a surrogate marker of antiangiogenic activity in patients treated with endostatin
    • Heymach J, Kulke M, Fuchs C, et al. Circulating endothelial cells as a surrogate marker of antiangiogenic activity in patients treated with endostatin. Proc Am Soc Clin Oncol 2003;22:979.
    • (2003) Proc Am Soc Clin Oncol , vol.22 , pp. 979
    • Heymach, J.1    Kulke, M.2    Fuchs, C.3
  • 31
    • 0038599016 scopus 로고    scopus 로고
    • Clinical evaluation of the novel vascular-targeting agent, ZD6126: Assessment of toxicity and surrogate markers of vascular damage
    • Radema SA, Beerepoot LV, Witteveen PO, Gebbink MF, Wheeler C, Voest EE. Clinical evaluation of the novel vascular-targeting agent, ZD6126: assessment of toxicity and surrogate markers of vascular damage. Proc Am Soc Clin Oncol 2002:439.
    • (2002) Proc Am Soc Clin Oncol , vol.439
    • Radema, S.A.1    Beerepoot, L.V.2    Witteveen, P.O.3    Gebbink, M.F.4    Wheeler, C.5    Voest, E.E.6
  • 32
    • 0037102369 scopus 로고    scopus 로고
    • ZD6474 inhibits vascular endothelial growth factor signaling, angiogenesis, and tumor growth following oral administration
    • Wedge SR, Ogilvie DJ, Dukes M, et al. ZD6474 inhibits vascular endothelial growth factor signaling, angiogenesis, and tumor growth following oral administration. Cancer Res 2002;62:4645-55.
    • (2002) Cancer Res , vol.62 , pp. 4645-4655
    • Wedge, S.R.1    Ogilvie, D.J.2    Dukes, M.3
  • 33
    • 18244362012 scopus 로고    scopus 로고
    • ZD6474, a novel antiangiogenic agent, in combination with docetaxel in patients with NSCLC: Results of the run-in phase of a two-part, randomized phase II study
    • Heymach JV, Dong RP, Dimery I, et al. ZD6474, a novel antiangiogenic agent, in combination with docetaxel in patients with NSCLC: results of the run-in phase of a two-part, randomized phase II study. Proc Am Soc Clin Oncol 2004;23:811.
    • (2004) Proc Am Soc Clin Oncol , vol.23 , pp. 811
    • Heymach, J.V.1    Dong, R.P.2    Dimery, I.3
  • 34
    • 0037115398 scopus 로고    scopus 로고
    • ZD6126: A novel vascular-targeting agent that causes selective destruction of tumor vasculature
    • Davis PD, Dougherty GJ, Blakey DC, et al. ZD6126: a novel vascular-targeting agent that causes selective destruction of tumor vasculature. Cancer Res 2002;62:7247-53.
    • (2002) Cancer Res , vol.62 , pp. 7247-7253
    • Davis, P.D.1    Dougherty, G.J.2    Blakey, D.C.3
  • 35
    • 0035821293 scopus 로고    scopus 로고
    • Vascular endothelial growth factor and angiopoietin-1 stimulate postnatal hematopoiesis by recruitment of vasculogenic and hematopoietic stem cells
    • Hattori K, Dias S, Heissig B, et al. Vascular endothelial growth factor and angiopoietin-1 stimulate postnatal hematopoiesis by recruitment of vasculogenic and hematopoietic stem cells. J Exp Med 2001;193:1005-14.
    • (2001) J Exp Med , vol.193 , pp. 1005-1014
    • Hattori, K.1    Dias, S.2    Heissig, B.3
  • 36
    • 0642364991 scopus 로고    scopus 로고
    • Genetic loci that control vascular endothelial growth factor-induced angiogenesis
    • Rogers MS, Rohan RM, Birsner AE, D'Amato RJ. Genetic loci that control vascular endothelial growth factor-induced angiogenesis. FASEB J 2003;17: 2112-4.
    • (2003) FASEB J , vol.17 , pp. 2112-2114
    • Rogers, M.S.1    Rohan, R.M.2    Birsner, A.E.3    D'Amato, R.J.4
  • 37
    • 0034032882 scopus 로고    scopus 로고
    • Antiangiogenic scheduling of chemotherapy improves efficacy against experimental drug-resistant cancer
    • Browder T, Butterfieid CE, Kraling BM, et al. Antiangiogenic scheduling of chemotherapy improves efficacy against experimental drug-resistant cancer. Cancer Res 2000;60:1878-86.
    • (2000) Cancer Res , vol.60 , pp. 1878-1886
    • Browder, T.1    Butterfieid, C.E.2    Kraling, B.M.3
  • 38
    • 0037134709 scopus 로고    scopus 로고
    • Clinical application of antiangiogenic therapy: Microvessel density, what it does and doesn't tell us
    • Hlkatky L, Hahnfeldt P, Folkman J. Clinical application of antiangiogenic therapy: microvessel density, what it does and doesn't tell us. J Natl Cancer Inst 2002;94:883-93.
    • (2002) J Natl Cancer Inst , vol.94 , pp. 883-893
    • Hlkatky, L.1    Hahnfeldt, P.2    Folkman, J.3
  • 39
    • 0033406794 scopus 로고    scopus 로고
    • Endothelial progenitor cells as putative targets for angiostatin
    • Ito H, Rovira II, Bloom ML, et al. Endothelial progenitor cells as putative targets for angiostatin. Cancer Res 1999;59:5875-7.
    • (1999) Cancer Res , vol.59 , pp. 5875-5877
    • Ito, H.1    Rovira, I.I.2    Bloom, M.L.3
  • 40
    • 0036278972 scopus 로고    scopus 로고
    • Antitumor activity of the novel vascular targeting agent ZD6126 in a panel of tumor models
    • Blakey DC, Westwood FR, Walker M, et al. Antitumor activity of the novel vascular targeting agent ZD6126 in a panel of tumor models. Clin Cancer Res 2002;8:1974-83.
    • (2002) Clin Cancer Res , vol.8 , pp. 1974-1983
    • Blakey, D.C.1    Westwood, F.R.2    Walker, M.3
  • 41
    • 0142155561 scopus 로고    scopus 로고
    • Vascular targeting effects of ZD6126 in a C3H mouse mammary carcinoma and the enhancement of radiation response
    • Horsman MR, Murata R. Vascular targeting effects of ZD6126 in a C3H mouse mammary carcinoma and the enhancement of radiation response. Int J Radiat Oncol Biol Phys 2003;57:1047-55.
    • (2003) Int J Radiat Oncol Biol Phys , vol.57 , pp. 1047-1055
    • Horsman, M.R.1    Murata, R.2
  • 42
    • 0036261824 scopus 로고    scopus 로고
    • Efficient mobilization and recruitment of marrow-derived endothelial and hematopoietic stem cells by adenoviral vectors expressing angiogenic factors
    • Rafii S, Heissig B, Hattori K. Efficient mobilization and recruitment of marrow-derived endothelial and hematopoietic stem cells by adenoviral vectors expressing angiogenic factors. Gene Ther 2002;9:631-41.
    • (2002) Gene Ther , vol.9 , pp. 631-641
    • Rafii, S.1    Heissig, B.2    Hattori, K.3
  • 43
    • 0035836697 scopus 로고    scopus 로고
    • Comparative evaluation of the antitumor activity of antiangiogenic proteins delivered by gene transfer
    • Kuo CJ, Farnebo F, Yu EY, et al. Comparative evaluation of the antitumor activity of antiangiogenic proteins delivered by gene transfer. Proc Natl Acad Sci U S A 2001;98:4605-10.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 4605-4610
    • Kuo, C.J.1    Farnebo, F.2    Yu, E.Y.3
  • 44
    • 0038497912 scopus 로고    scopus 로고
    • Vascular endothelial growth factor receptor-2 induces survival of hematopoietic progenitor cells
    • Larrivee B, Lane DR, Rollet I, Olive PL, Humphries RK, Karsan A. Vascular endothelial growth factor receptor-2 induces survival of hematopoietic progenitor cells. J Biol Chem 2003;278:22006-13.
    • (2003) J Biol Chem , vol.278 , pp. 22006-22013
    • Larrivee, B.1    Lane, D.R.2    Rollet, I.3    Olive, P.L.4    Humphries, R.K.5    Karsan, A.6
  • 45
    • 0033152361 scopus 로고    scopus 로고
    • Sickle cell anemia as a possible state of enhanced anti-apoptotic tone: Survival effect of vascular endothelial growth factor on circulating and unanchored endothelial cells
    • Solovey A, Gui L, Ramakrishnan S, Steinberg MH, Hebbel RP. Sickle cell anemia as a possible state of enhanced anti-apoptotic tone: survival effect of vascular endothelial growth factor on circulating and unanchored endothelial cells. Blood 1999;93:3824-30.
    • (1999) Blood , vol.93 , pp. 3824-3830
    • Solovey, A.1    Gui, L.2    Ramakrishnan, S.3    Steinberg, M.H.4    Hebbel, R.P.5
  • 46
    • 0033989026 scopus 로고    scopus 로고
    • Origins of circulating endothelial cells and endothelial outgrowth from blood
    • Lin Y, Weisdorf DJ, Solovey A, Hebbel RP. Origins of circulating endothelial cells and endothelial outgrowth from blood. J Clin Invest 2000;105:71-7.
    • (2000) J Clin Invest , vol.105 , pp. 71-77
    • Lin, Y.1    Weisdorf, D.J.2    Solovey, A.3    Hebbel, R.P.4
  • 47
    • 3042548695 scopus 로고    scopus 로고
    • Inhibition of vascular endothelial growth factor (VEGF) signaling in cancer causes loss of endothelial fenestrations, regression of tumor vessels, and appearance of basement membrane ghosts
    • Inai T, Mancuso M, Hashizume H, et al. Inhibition of vascular endothelial growth factor (VEGF) signaling in cancer causes loss of endothelial fenestrations, regression of tumor vessels, and appearance of basement membrane ghosts. Am J Pathol 2004; 165:35-52.
    • (2004) Am J Pathol , vol.165 , pp. 35-52
    • Inai, T.1    Mancuso, M.2    Hashizume, H.3
  • 48
    • 0036831559 scopus 로고    scopus 로고
    • Vascular and haematopoietic stem cells: Novel targets for anti-angiogenesis therapy?
    • Rafii S, Lyden D, Benezra R, Hattori K, Heissig B. Vascular and haematopoietic stem cells: novel targets for anti-angiogenesis therapy? Nat Rev Cancer 2002;2:826-35.
    • (2002) Nat Rev Cancer , vol.2 , pp. 826-835
    • Rafii, S.1    Lyden, D.2    Benezra, R.3    Hattori, K.4    Heissig, B.5
  • 49
    • 0035160312 scopus 로고    scopus 로고
    • Impaired recruitment of bone-marrow-derived endothelial and hematopoietic precursor cells blocks tumor angiogenesis and growth
    • Lyden D, Hattori K, Dias S, et al. Impaired recruitment of bone-marrow-derived endothelial and hematopoietic precursor cells blocks tumor angiogenesis and growth. Nat Med 2001;7:1194-201.
    • (2001) Nat Med , vol.7 , pp. 1194-1201
    • Lyden, D.1    Hattori, K.2    Dias, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.