Length-independent structural similarities enrich the antibody CDR canonical class model

mAbs

Volumn 8, Issue 4, 2016, Pages 751-760

  Nowak, Jaroslaw ^a   Baker, Terry ^b   Georges, Guy ^c   Kelm, Sebastian ^b   Klostermann, Stefan ^c   Shi, Jiye ^b   Sridharan, Sudharsan ^d   Deane, Charlotte M ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UCB PHARMA   (Belgium)

^c ROCHE INNOVATION CENTER MUNICH   (Germany)

^d MEDIMMUNE   (United States)

Author keywords

Canonical class; Clustering; Complementarity determining regions; Length independent; Loop modeling

Indexed keywords

ANTIBODY COMBINING SITE; AREA UNDER THE CURVE; ARTICLE; CANONICAL ANALYSIS; CLUSTER ANALYSIS; COMPLEMENTARITY DETERMINING REGION; DYNAMIC TIME WARPING; GERMLINE STEM CELL; HUMAN; HUMAN CELL; INFORMATION PROCESSING; METHODOLOGY; MODEL; NEXT GENERATION SEQUENCING; NONHUMAN; PREDICTION; RECEIVER OPERATING CHARACTERISTIC; AMINO ACID SEQUENCE; ANIMAL; CHEMISTRY; CLASSIFICATION; HIGH THROUGHPUT SCREENING; MOLECULAR GENETICS; MOLECULAR MODEL;

AMINO ACID SEQUENCE; ANIMALS; COMPLEMENTARITY DETERMINING REGIONS; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA;

EID: 84971384297     PISSN: 19420862     EISSN: 19420870     Source Type: Journal    
DOI: 10.1080/19420862.2016.1158370     Document Type: Article

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