메뉴 건너뛰기




Volumn 79, Issue 5, 2011, Pages 1513-1524

Structural repertoire of immunoglobulin λ light chains

Author keywords

Canonical structures; Immunoglobulins; Lambda chains

Indexed keywords

IMMUNOGLOBULIN LAMBDA CHAIN;

EID: 79954591066     PISSN: 08873585     EISSN: 10970134     Source Type: Journal    
DOI: 10.1002/prot.22979     Document Type: Article
Times cited : (30)

References (58)
  • 1
    • 0014828908 scopus 로고
    • An analysis of the sequences of the variable regions of Bence Jones proteins and myeloma light chains and their implications for antibody complementarity
    • Wu TT, Kabat EA. An analysis of the sequences of the variable regions of Bence Jones proteins and myeloma light chains and their implications for antibody complementarity. J Exp Med 1970; 132: 211-250.
    • (1970) J Exp Med , vol.132 , pp. 211-250
    • Wu, T.T.1    Kabat, E.A.2
  • 2
    • 0015326079 scopus 로고
    • Construction of a three-dimensional model of the polypeptide backbone of the variable region of kappa immunoglobulin light chains
    • Kabat EA, Wu TT. Construction of a three-dimensional model of the polypeptide backbone of the variable region of kappa immunoglobulin light chains. Proc Natl Acad Sci USA 1972; 69: 960-964.
    • (1972) Proc Natl Acad Sci USA , vol.69 , pp. 960-964
    • Kabat, E.A.1    Wu, T.T.2
  • 3
    • 0018102566 scopus 로고
    • Variable region genes for the immunoglobulin framework are assembled from small segments of DNA-a hypothesis
    • Kabat EA, Wu TT, Bilofsky H. Variable region genes for the immunoglobulin framework are assembled from small segments of DNA-a hypothesis. Proc Natl Acad Sci USA 1978; 75: 2429-2433.
    • (1978) Proc Natl Acad Sci USA , vol.75 , pp. 2429-2433
    • Kabat, E.A.1    Wu, T.T.2    Bilofsky, H.3
  • 5
    • 33646181086 scopus 로고    scopus 로고
    • Mechanism and control of V(D)J recombination at the immunoglobulin heavy chain locus
    • Jung D, Giallourakis C, Mostoslavsky R, Alt FW. Mechanism and control of V(D)J recombination at the immunoglobulin heavy chain locus. Annu Rev Immunol 2006; 24: 541-570.
    • (2006) Annu Rev Immunol , vol.24 , pp. 541-570
    • Jung, D.1    Giallourakis, C.2    Mostoslavsky, R.3    Alt, F.W.4
  • 8
    • 0023185258 scopus 로고
    • Regulation of kappa/lambda immunoglobulin light chain expression in normal murine lymphocytes
    • Woloschak GE, Krco CJ. Regulation of kappa/lambda immunoglobulin light chain expression in normal murine lymphocytes. Mol Immunol 1987; 24: 751-757.
    • (1987) Mol Immunol , vol.24 , pp. 751-757
    • Woloschak, G.E.1    Krco, C.J.2
  • 10
    • 0028961335 scopus 로고
    • SCOP: a structural classification of proteins database for the investigation of sequences and structures
    • Murzin AG, Brenner SE, Hubbard T, Chothia C. SCOP: a structural classification of proteins database for the investigation of sequences and structures. J Mol Biol 1995; 247: 536-540.
    • (1995) J Mol Biol , vol.247 , pp. 536-540
    • Murzin, A.G.1    Brenner, S.E.2    Hubbard, T.3    Chothia, C.4
  • 11
    • 0023278330 scopus 로고
    • Canonical structures for the hypervariable regions of immunoglobulins
    • Chothia C, Lesk AM. Canonical structures for the hypervariable regions of immunoglobulins. J Mol Biol 1987; 196: 901-917.
    • (1987) J Mol Biol , vol.196 , pp. 901-917
    • Chothia, C.1    Lesk, A.M.2
  • 12
    • 0025063143 scopus 로고
    • Framework residue 71 is a major determinant of the position and conformation of the second hypervariable region in the VH domains of immunoglobulins
    • Tramontano A, Chothia C, Lesk AM. Framework residue 71 is a major determinant of the position and conformation of the second hypervariable region in the VH domains of immunoglobulins. J Mol Biol 1990; 215: 175-182.
    • (1990) J Mol Biol , vol.215 , pp. 175-182
    • Tramontano, A.1    Chothia, C.2    Lesk, A.M.3
  • 13
    • 0026559783 scopus 로고
    • Antibody framework residues affecting the conformation of the hypervariable loops
    • Foote J, Winter G. Antibody framework residues affecting the conformation of the hypervariable loops. J Mol Biol 1992; 224: 487-499.
    • (1992) J Mol Biol , vol.224 , pp. 487-499
    • Foote, J.1    Winter, G.2
  • 14
    • 0029610794 scopus 로고
    • Canonical structure repertoire of the antigen-binding site of immunoglobulins suggests strong geometrical restrictions associated to the mechanism of immune recognition
    • Vargas-Madrazo E, Lara-Ochoa F, Almagro JC. Canonical structure repertoire of the antigen-binding site of immunoglobulins suggests strong geometrical restrictions associated to the mechanism of immune recognition. J Mol Biol 1995; 254: 497-504.
    • (1995) J Mol Biol , vol.254 , pp. 497-504
    • Vargas-Madrazo, E.1    Lara-Ochoa, F.2    Almagro, J.C.3
  • 15
    • 0031558798 scopus 로고    scopus 로고
    • Standard conformations for the canonical structures of immunoglobulins
    • Al-Lazikani B, Lesk AM, Chothia C. Standard conformations for the canonical structures of immunoglobulins. J Mol Biol 1997; 273: 927-948.
    • (1997) J Mol Biol , vol.273 , pp. 927-948
    • Al-Lazikani, B.1    Lesk, A.M.2    Chothia, C.3
  • 16
    • 0007006714 scopus 로고    scopus 로고
    • The differences between the structural repertoires of VH germ-line gene segments of mice and humans: implication for the molecular mechanism of the immune response
    • Almagro JC, Hernandez I, del Carmen Ramirez M, Vargas-Madrazo E. The differences between the structural repertoires of VH germ-line gene segments of mice and humans: implication for the molecular mechanism of the immune response. Mol Immunol 1997; 34: 1199-1214.
    • (1997) Mol Immunol , vol.34 , pp. 1199-1214
    • Almagro, J.C.1    Hernandez, I.2    del Carmen Ramirez, M.3    Vargas-Madrazo, E.4
  • 17
    • 0031939497 scopus 로고    scopus 로고
    • Structural differences between the repertoires of mouse and human germline genes and their evolutionary implications
    • Almagro JC, Hernandez I, Ramirez MC, Vargas-Madrazo E. Structural differences between the repertoires of mouse and human germline genes and their evolutionary implications. Immunogenetics 1998; 47: 355-363.
    • (1998) Immunogenetics , vol.47 , pp. 355-363
    • Almagro, J.C.1    Hernandez, I.2    Ramirez, M.C.3    Vargas-Madrazo, E.4
  • 18
    • 0036568230 scopus 로고    scopus 로고
    • Modifications to canonical structure sequence patterns: analysis for L1 and L3
    • Vargas-Madrazo E, Paz-Garcia E. Modifications to canonical structure sequence patterns: analysis for L1 and L3. Proteins 2002; 47: 250-254.
    • (2002) Proteins , vol.47 , pp. 250-254
    • Vargas-Madrazo, E.1    Paz-Garcia, E.2
  • 19
    • 57349097173 scopus 로고    scopus 로고
    • Structural classification of CDR-H3 revisited: a lesson in antibody modeling
    • Kuroda D, Shirai H, Kobori M, Nakamura H. Structural classification of CDR-H3 revisited: a lesson in antibody modeling. Proteins 2008; 73: 608-620.
    • (2008) Proteins , vol.73 , pp. 608-620
    • Kuroda, D.1    Shirai, H.2    Kobori, M.3    Nakamura, H.4
  • 20
    • 65249106714 scopus 로고    scopus 로고
    • Systematic classification of CDR-L3 in antibodies: implications of the light chain subtypes and the VL-VH interface
    • Kuroda D, Shirai H, Kobori M, Nakamura H. Systematic classification of CDR-L3 in antibodies: implications of the light chain subtypes and the VL-VH interface. Proteins 2009; 75: 139-146.
    • (2009) Proteins , vol.75 , pp. 139-146
    • Kuroda, D.1    Shirai, H.2    Kobori, M.3    Nakamura, H.4
  • 21
    • 0347755625 scopus 로고    scopus 로고
    • IMGT/3Dstructure-DB and IMGT/StructuralQuery, a database and a tool for immunoglobulin, T cell receptor and MHC structural data
    • Kaas Q, Ruiz M, Lefranc MP. IMGT/3Dstructure-DB and IMGT/StructuralQuery, a database and a tool for immunoglobulin, T cell receptor and MHC structural data. Nucleic Acids Res 2004; 32(Database issue): D208-D210.
    • (2004) Nucleic Acids Res , vol.32 , Issue.DATABASE ISSUE
    • Kaas, Q.1    Ruiz, M.2    Lefranc, M.P.3
  • 22
    • 0035072551 scopus 로고    scopus 로고
    • Clustering of highly homologous sequences to reduce the size of large protein databases
    • Li W, Jaroszewski L, Godzik A. Clustering of highly homologous sequences to reduce the size of large protein databases. Bioinformatics (Oxford, England) 2001; 17: 282-283.
    • (2001) Bioinformatics (Oxford, England) , vol.17 , pp. 282-283
    • Li, W.1    Jaroszewski, L.2    Godzik, A.3
  • 23
    • 48049124972 scopus 로고    scopus 로고
    • Analysis and improvements to Kabat and structurally correct numbering of antibody variable domains
    • Abhinandan KR, Martin AC. Analysis and improvements to Kabat and structurally correct numbering of antibody variable domains. Mol Immunol 2008; 45: 3832-3839.
    • (2008) Mol Immunol , vol.45 , pp. 3832-3839
    • Abhinandan, K.R.1    Martin, A.C.2
  • 24
    • 0042622381 scopus 로고    scopus 로고
    • LGA-a method for finding 3D similarities in protein structures
    • Zemla A. LGA-a method for finding 3D similarities in protein structures. Nucleic Acids Res 2003; 31: 3370-3374.
    • (2003) Nucleic Acids Res , vol.31 , pp. 3370-3374
    • Zemla, A.1
  • 25
    • 0032605828 scopus 로고    scopus 로고
    • Processing and analysis of CASP3 protein structure predictions
    • Zemla A, Venclovas C, Moult J, Fidelis K. Processing and analysis of CASP3 protein structure predictions. Proteins 1999; 37(Suppl 3): 22-29.
    • (1999) Proteins , vol.37 , Issue.SUPPL. 3 , pp. 22-29
    • Zemla, A.1    Venclovas, C.2    Moult, J.3    Fidelis, K.4
  • 26
    • 10344232638 scopus 로고    scopus 로고
    • Scoring function for automated assessment of protein structure template quality
    • Zhang Y, Skolnick J. Scoring function for automated assessment of protein structure template quality. Proteins 2004; 57: 702-710.
    • (2004) Proteins , vol.57 , pp. 702-710
    • Zhang, Y.1    Skolnick, J.2
  • 27
    • 0023453329 scopus 로고
    • Silhouettes: a graphical aid to the interpretation and validation of cluster analysis
    • Peter R. Silhouettes: a graphical aid to the interpretation and validation of cluster analysis. J Comput Appl Math 1987; 20: 53-65.
    • (1987) J Comput Appl Math , vol.20 , pp. 53-65
    • Peter, R.1
  • 28
    • 35748978234 scopus 로고    scopus 로고
    • Empirical characterization of random forest variable importance measures
    • Archer KJ, Kimes RV. Empirical characterization of random forest variable importance measures. Comp Stat Data Anal 2008; 52: 2249-2260.
    • (2008) Comp Stat Data Anal , vol.52 , pp. 2249-2260
    • Archer, K.J.1    Kimes, R.V.2
  • 29
    • 0035478854 scopus 로고    scopus 로고
    • Random forests
    • Breiman L. Random forests. Mach Learn 2001; 45: 5-32.
    • (2001) Mach Learn , vol.45 , pp. 5-32
    • Breiman, L.1
  • 31
    • 0345040873 scopus 로고    scopus 로고
    • Classification and regression by randomForest
    • Liaw A, Wiener M. Classification and regression by randomForest. R News 2002; 2: 18-22.
    • (2002) R News , vol.2 , pp. 18-22
    • Liaw, A.1    Wiener, M.2
  • 32
    • 35348880944 scopus 로고    scopus 로고
    • Four primordial immunoglobulin light chain isotypes, including lambda and kappa, identified in the most primitive living jawed vertebrates
    • Criscitiello MF, Flajnik MF. Four primordial immunoglobulin light chain isotypes, including lambda and kappa, identified in the most primitive living jawed vertebrates. Eur J Immunol 2007; 37: 2683-2694.
    • (2007) Eur J Immunol , vol.37 , pp. 2683-2694
    • Criscitiello, M.F.1    Flajnik, M.F.2
  • 33
    • 33745622868 scopus 로고    scopus 로고
    • Two Sample Logo: a graphical representation of the differences between two sets of sequence alignments
    • Vacic V, Iakoucheva LM, Radivojac P. Two Sample Logo: a graphical representation of the differences between two sets of sequence alignments. Bioinformatics (Oxford, England) 2006; 22: 1536-1537.
    • (2006) Bioinformatics (Oxford, England) , vol.22 , pp. 1536-1537
    • Vacic, V.1    Iakoucheva, L.M.2    Radivojac, P.3
  • 34
    • 37049184038 scopus 로고
    • Antibody gene structure
    • Kabat EA. Antibody gene structure. Science 1979; 203: 400.
    • (1979) Science , vol.203 , pp. 400
    • Kabat, E.A.1
  • 35
    • 0027499142 scopus 로고
    • Conformation of complementarity determining region L1 loop in murine IgG lambda light chain extends the repertoire of canonical forms
    • Wu S, Cygler M. Conformation of complementarity determining region L1 loop in murine IgG lambda light chain extends the repertoire of canonical forms. J Mol Biol 1993; 229: 597-601.
    • (1993) J Mol Biol , vol.229 , pp. 597-601
    • Wu, S.1    Cygler, M.2
  • 36
    • 0030589039 scopus 로고    scopus 로고
    • Structural families in loops of homologous proteins: automatic classification, modelling and application to antibodies
    • Martin AC, Thornton JM. Structural families in loops of homologous proteins: automatic classification, modelling and application to antibodies. J Mol Biol 1996; 263: 800-815.
    • (1996) J Mol Biol , vol.263 , pp. 800-815
    • Martin, A.C.1    Thornton, J.M.2
  • 37
    • 13444273444 scopus 로고    scopus 로고
    • IMGT/GENE-DB: a comprehensive database for human and mouse immunoglobulin and T cell receptor genes
    • Giudicelli V, Chaume D, Lefranc MP. IMGT/GENE-DB: a comprehensive database for human and mouse immunoglobulin and T cell receptor genes. Nucleic Acids Res 2005; 33(Database issue): D256-D261.
    • (2005) Nucleic Acids Res , vol.33 , Issue.DATABASE ISSUE
    • Giudicelli, V.1    Chaume, D.2    Lefranc, M.P.3
  • 38
    • 0345436074 scopus 로고    scopus 로고
    • Molecular mechanisms and selection influence the generation of the human V lambda J lambda repertoire
    • Farner NL, Dorner T, Lipsky PE. Molecular mechanisms and selection influence the generation of the human V lambda J lambda repertoire. J Immunol 1999; 162: 2137-2145.
    • (1999) J Immunol , vol.162 , pp. 2137-2145
    • Farner, N.L.1    Dorner, T.2    Lipsky, P.E.3
  • 39
  • 40
    • 34548242744 scopus 로고    scopus 로고
    • The lambda gene immunoglobulin repertoire of human neonatal B cells
    • Richl P, Stern U, Lipsky PE, Girschick HJ. The lambda gene immunoglobulin repertoire of human neonatal B cells. Mol Immunol 2008; 45: 320-327.
    • (2008) Mol Immunol , vol.45 , pp. 320-327
    • Richl, P.1    Stern, U.2    Lipsky, P.E.3    Girschick, H.J.4
  • 41
    • 0025146189 scopus 로고
    • The products of pre-B cell-specific genes (lambda 5 and VpreB) and the immunoglobulin mu chain form a complex that is transported onto the cell surface
    • Tsubata T, Reth M. The products of pre-B cell-specific genes (lambda 5 and VpreB) and the immunoglobulin mu chain form a complex that is transported onto the cell surface. J Exp Med 1990; 172: 973-976.
    • (1990) J Exp Med , vol.172 , pp. 973-976
    • Tsubata, T.1    Reth, M.2
  • 42
    • 0028566270 scopus 로고
    • A revised set of potentials for beta-turn formation in proteins
    • Hutchinson EG, Thornton JM. A revised set of potentials for beta-turn formation in proteins. Protein Sci 1994; 3: 2207-2216.
    • (1994) Protein Sci , vol.3 , pp. 2207-2216
    • Hutchinson, E.G.1    Thornton, J.M.2
  • 45
    • 0017153347 scopus 로고
    • Kappa and lambda light chain disease: survival rates and clinical manifestations
    • Shustik C, Bergsagel DE, Pruzanski W. Kappa and lambda light chain disease: survival rates and clinical manifestations. Blood 1976; 48: 41-51.
    • (1976) Blood , vol.48 , pp. 41-51
    • Shustik, C.1    Bergsagel, D.E.2    Pruzanski, W.3
  • 46
    • 0021071062 scopus 로고
    • Immunoglobulin-related (AL) amyloidosis
    • Husby G. Immunoglobulin-related (AL) amyloidosis. Clin Exp Rheumatol 1983; 1: 353-358.
    • (1983) Clin Exp Rheumatol , vol.1 , pp. 353-358
    • Husby, G.1
  • 48
    • 33645211013 scopus 로고    scopus 로고
    • What is the current evidence for antigen involvement in the development of chronic lymphocytic leukemia?
    • Tobin G, Rosen A, Rosenquist R. What is the current evidence for antigen involvement in the development of chronic lymphocytic leukemia? Hematol Oncol 2006; 24: 7-13.
    • (2006) Hematol Oncol , vol.24 , pp. 7-13
    • Tobin, G.1    Rosen, A.2    Rosenquist, R.3
  • 49
    • 79251598995 scopus 로고    scopus 로고
    • A new clustering of antibody CDR loop conformations
    • doi:10.1016/j.jmb.2010.10.030.
    • North B, Lehmann A, Dunbrack RL, Jr. A new clustering of antibody CDR loop conformations. J Mol Biol doi:10.1016/j.jmb.2010.10.030.
    • J Mol Biol
    • North, B.1    Lehmann, A.2    Dunbrack Jr, R.L.3
  • 50
    • 0034458999 scopus 로고    scopus 로고
    • WAM: an improved algorithm for modelling antibodies on the WEB
    • Whitelegg NR, Rees AR. WAM: an improved algorithm for modelling antibodies on the WEB. Protein Eng 2000; 13: 819-824.
    • (2000) Protein Eng , vol.13 , pp. 819-824
    • Whitelegg, N.R.1    Rees, A.R.2
  • 52
    • 67849111558 scopus 로고    scopus 로고
    • RosettaAntibody: antibody variable region homology modeling server
    • Sircar A, Kim ET, Gray JJ. RosettaAntibody: antibody variable region homology modeling server. Nucleic Acids Res 2009; 37(Web Server issue): W474-W479.
    • (2009) Nucleic Acids Res , vol.37 , Issue.WEB SERVER ISSUE
    • Sircar, A.1    Kim, E.T.2    Gray, J.J.3
  • 54
    • 34249017414 scopus 로고    scopus 로고
    • A molecular immunology approach to antibody humanization and functional optimization
    • Lazar GA, Desjarlais JR, Jacinto J, Karki S, Hammond PW. A molecular immunology approach to antibody humanization and functional optimization. Mol Immunol 2007; 44: 1986-1998.
    • (2007) Mol Immunol , vol.44 , pp. 1986-1998
    • Lazar, G.A.1    Desjarlais, J.R.2    Jacinto, J.3    Karki, S.4    Hammond, P.W.5
  • 55
    • 38649139063 scopus 로고    scopus 로고
    • Critical contribution of VH-VL interaction to reshaping of an antibody: the case of humanization of anti-lysozyme antibody, HyHEL-10
    • Nakanishi T, Tsumoto K, Yokota A, Kondo H, Kumagai I. Critical contribution of VH-VL interaction to reshaping of an antibody: the case of humanization of anti-lysozyme antibody, HyHEL-10. Protein Sci 2008; 17: 261-270.
    • (2008) Protein Sci , vol.17 , pp. 261-270
    • Nakanishi, T.1    Tsumoto, K.2    Yokota, A.3    Kondo, H.4    Kumagai, I.5
  • 56
    • 60749137123 scopus 로고    scopus 로고
    • Functional humanization of an anti-CD16 Fab fragment: obstacles of switching from murine lambda to human lambda or kappa light chains
    • Schlapschy M, Fogarasi M, Gruber H, Gresch O, Schafer C, Aguib Y, Skerra A. Functional humanization of an anti-CD16 Fab fragment: obstacles of switching from murine lambda to human lambda or kappa light chains. Protein Eng Des Sel 2009; 22: 175-188.
    • (2009) Protein Eng Des Sel , vol.22 , pp. 175-188
    • Schlapschy, M.1    Fogarasi, M.2    Gruber, H.3    Gresch, O.4    Schafer, C.5    Aguib, Y.6    Skerra, A.7
  • 57
    • 33750441823 scopus 로고    scopus 로고
    • Differences in potential for amino acid change after mutation reveals distinct strategies for kappa and lambda light-chain variation
    • Hershberg U, Shlomchik MJ. Differences in potential for amino acid change after mutation reveals distinct strategies for kappa and lambda light-chain variation. Proc Natl Acad Sci USA 2006; 103: 15963-15968.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 15963-15968
    • Hershberg, U.1    Shlomchik, M.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.