메뉴 건너뛰기




Volumn 11, Issue 5, 2016, Pages

BANK1 regulates IgG production in a lupus model by controlling TLR7-dependent STAT1 activation

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIBODY; B CELL ACTIVATING FACTOR; CHEMOKINE RECEPTOR CXCR4; IMMUNOGLOBULIN G; IMMUNOGLOBULIN G ANTIBODY; INTERLEUKIN 6; SERINE; STAT1 PROTEIN; TOLL LIKE RECEPTOR 7; TYROSINE; BANK1 PROTEIN, MOUSE; MEMBRANE PROTEIN; SIGNAL TRANSDUCING ADAPTOR PROTEIN; STAT1 PROTEIN, MOUSE; TLR7 PROTEIN, MOUSE;

EID: 84971373690     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0156302     Document Type: Article
Times cited : (30)

References (44)
  • 1
    • 0037080952 scopus 로고    scopus 로고
    • BANK regulates BCR-induced calcium mobilization by promoting tyrosine phosphorylation of IP(3) receptor
    • PMID: 11782428
    • Yokoyama K, Su Ih IH, Tezuka T, Yasuda T, Mikoshiba K, Tarakhovsky A et al. BANK regulates BCR-induced calcium mobilization by promoting tyrosine phosphorylation of IP(3) receptor. Embo J, 2002; 21:83-92. PMID: 11782428
    • (2002) Embo J , vol.21 , pp. 83-92
    • Yokoyama, K.1    Su Ih, I.H.2    Tezuka, T.3    Yasuda, T.4    Mikoshiba, K.5    Tarakhovsky, A.6
  • 2
    • 33645000184 scopus 로고    scopus 로고
    • BANK negatively regulates Akt activation and subsequent B cell responses
    • PMID: 16546095
    • Aiba Y, Yamazaki T, Okada T, Gotoh K, Sanjo H, Ogata M et al. BANK negatively regulates Akt activation and subsequent B cell responses. Immunity, 2006; 24:259-68. PMID: 16546095
    • (2006) Immunity , vol.24 , pp. 259-268
    • Aiba, Y.1    Yamazaki, T.2    Okada, T.3    Gotoh, K.4    Sanjo, H.5    Ogata, M.6
  • 3
    • 84875469008 scopus 로고    scopus 로고
    • BANK1 and BLK Act through Phospholipase C Gamma 2 in B-Cell Signaling
    • PMID: 23555801
    • Bernal-Quiros M, Wu YY, Alarcon-Riquelme ME, Castillejo-Lopez C. BANK1 and BLK Act through Phospholipase C Gamma 2 in B-Cell Signaling. PLoS ONE, 2013; 8:e59842. doi: 10.1371/journal.pone.0059842 PMID: 23555801
    • (2013) PLoS ONE , vol.8
    • Bernal-Quiros, M.1    Wu, Y.Y.2    Alarcon-Riquelme, M.E.3    Castillejo-Lopez, C.4
  • 6
    • 38649138296 scopus 로고    scopus 로고
    • Functional variants in the B-cell gene BANK1 are associated with systemic lupus erythematosus
    • PMID: 18204447
    • Kozyrev SV, Abelson AK, Wojcik J, Zaghlool A, Linga Reddy MV, Sanchez E et al. Functional variants in the B-cell gene BANK1 are associated with systemic lupus erythematosus. Nat Genet, 2008; 40:211-6. doi: 10.1038/ng.79 PMID: 18204447
    • (2008) Nat Genet , vol.40 , pp. 211-216
    • Kozyrev, S.V.1    Abelson, A.K.2    Wojcik, J.3    Zaghlool, A.4    Linga Reddy, M.V.5    Sanchez, E.6
  • 7
    • 70350521796 scopus 로고    scopus 로고
    • BANK1 is a genetic risk factor for diffuse cutaneous systemic sclerosis and has additive effects with IRF5 and STAT4
    • PMID: 19877059
    • Dieude P, Wipff J, Guedj M, Ruiz B, Melchers I, Hachulla E et al. BANK1 is a genetic risk factor for diffuse cutaneous systemic sclerosis and has additive effects with IRF5 and STAT4. Arthritis Rheum, 2009; 60:3447-54. doi: 10.1002/art.24885 PMID: 19877059
    • (2009) Arthritis Rheum , vol.60 , pp. 3447-3454
    • Dieude, P.1    Wipff, J.2    Guedj, M.3    Ruiz, B.4    Melchers, I.5    Hachulla, E.6
  • 9
    • 69449090457 scopus 로고    scopus 로고
    • Rheumatoid arthritis does not share most of the newly identified systemic lupus erythematosus genetic factors
    • PMID: 19714582
    • Suarez-Gestal M, Calaza M, Dieguez-Gonzalez R, Perez-Pampin E, Pablos JL, Navarro F et al. Rheumatoid arthritis does not share most of the newly identified systemic lupus erythematosus genetic factors. Arthritis and Rheumatism, 2009; 60:2558-64. doi: 10.1002/art.24748 PMID: 19714582
    • (2009) Arthritis and Rheumatism , vol.60 , pp. 2558-2564
    • Suarez-Gestal, M.1    Calaza, M.2    Dieguez-Gonzalez, R.3    Perez-Pampin, E.4    Pablos, J.L.5    Navarro, F.6
  • 10
    • 33645960706 scopus 로고    scopus 로고
    • TLR signaling
    • PMID: 16410796
    • Kawai T, Akira S. TLR signaling. Cell Death Differ, 2006; 13:816-25. PMID: 16410796
    • (2006) Cell Death Differ , vol.13 , pp. 816-825
    • Kawai, T.1    Akira, S.2
  • 11
    • 77949903821 scopus 로고    scopus 로고
    • TLR9 regulates TLR7- and MyD88-dependent autoantibody production and disease in a murine model of lupus
    • PMID: 20089701
    • Nickerson KM, Christensen SR, Shupe J, Kashgarian M, Kim D, Elkon K et al. TLR9 regulates TLR7- and MyD88-dependent autoantibody production and disease in a murine model of lupus. J Immunol, 2010; 184:1840-8. doi: 10.4049/jimmunol.0902592 PMID: 20089701
    • (2010) J Immunol , vol.184 , pp. 1840-1848
    • Nickerson, K.M.1    Christensen, S.R.2    Shupe, J.3    Kashgarian, M.4    Kim, D.5    Elkon, K.6
  • 12
    • 77952242576 scopus 로고    scopus 로고
    • Critical role of TLR7 in the acceleration of systemic lupus erythematosus in TLR9-deficient mice
    • PMID: 19944565
    • Santiago-Raber ML, Dunand-Sauthier I, Wu T, Li QZ, Uematsu S, Akira S et al. Critical role of TLR7 in the acceleration of systemic lupus erythematosus in TLR9-deficient mice. Journal of autoimmunity, 2010; 34:339-48. doi: 10.1016/j.jaut.2009.11.001 PMID: 19944565
    • (2010) Journal of Autoimmunity , vol.34 , pp. 339-348
    • Santiago-Raber, M.L.1    Dunand-Sauthier, I.2    Wu, T.3    Li, Q.Z.4    Uematsu, S.5    Akira, S.6
  • 13
    • 33748470505 scopus 로고    scopus 로고
    • Toll-like receptor 7-dependent loss of B cell tolerance in pathogenic autoantibody knockin mice
    • PMID: 16973388
    • Berland R, Fernandez L, Kari E, Han JH, Lomakin I, Akira S et al. Toll-like receptor 7-dependent loss of B cell tolerance in pathogenic autoantibody knockin mice. Immunity, 2006; 25:429-40. PMID: 16973388
    • (2006) Immunity , vol.25 , pp. 429-440
    • Berland, R.1    Fernandez, L.2    Kari, E.3    Han, J.H.4    Lomakin, I.5    Akira, S.6
  • 14
    • 31044440025 scopus 로고    scopus 로고
    • Toll-like receptor 9 signaling protects against murine lupus
    • PMID: 16385525
    • Wu X, Peng SL. Toll-like receptor 9 signaling protects against murine lupus. Arthritis Rheum, 2006; 54:336-42. PMID: 16385525
    • (2006) Arthritis Rheum , vol.54 , pp. 336-342
    • Wu, X.1    Peng, S.L.2
  • 16
    • 84861665596 scopus 로고    scopus 로고
    • Role of type I interferons in the activation of autoreactive B cells
    • PMID: 22430248
    • Kiefer K, Oropallo MA, Cancro MP, Marshak-Rothstein A. Role of type I interferons in the activation of autoreactive B cells. Immunol Cell Biol, 2012; 90:498-504. doi: 10.1038/icb.2012.10 PMID: 22430248
    • (2012) Immunol Cell Biol , vol.90 , pp. 498-504
    • Kiefer, K.1    Oropallo, M.A.2    Cancro, M.P.3    Marshak-Rothstein, A.4
  • 17
    • 68149126174 scopus 로고    scopus 로고
    • Murine B cell response to TLR7 ligands depends on an IFN-beta feedback loop
    • PMID: 19587008
    • Green NM, Laws A, Kiefer K, Busconi L, Kim YM, Brinkmann MM et al. Murine B cell response to TLR7 ligands depends on an IFN-beta feedback loop. J Immunol, 2009; 183:1569-76. doi: 10.4049/jimmunol.0803899 PMID: 19587008
    • (2009) J Immunol , vol.183 , pp. 1569-1576
    • Green, N.M.1    Laws, A.2    Kiefer, K.3    Busconi, L.4    Kim, Y.M.5    Brinkmann, M.M.6
  • 18
    • 84919684042 scopus 로고    scopus 로고
    • Mechanisms of Jak/STAT signaling in immunity and disease
    • PMID: 25527793
    • Villarino AV, Kanno Y, Ferdinand JR, O'Shea JJ. Mechanisms of Jak/STAT signaling in immunity and disease. J Immunol, 2015; 194:21-7. doi: 10.4049/jimmunol.1401867 PMID: 25527793
    • (2015) J Immunol , vol.194 , pp. 21-27
    • Villarino, A.V.1    Kanno, Y.2    Ferdinand, J.R.3    O'Shea, J.J.4
  • 19
    • 77953691247 scopus 로고    scopus 로고
    • Toll-like receptor 7 (TLR7) modulates anti-nucleosomal autoantibody isotype and renal complement deposition in mice exposed to syngeneic late apoptotic cells
    • PMID: 19674980
    • Pan ZJ, Maier S, Schwarz K, Azbill J, Akira S, Uematsu S et al. Toll-like receptor 7 (TLR7) modulates anti-nucleosomal autoantibody isotype and renal complement deposition in mice exposed to syngeneic late apoptotic cells. Annals of the rheumatic diseases, 2010; 69:1195-9. doi: 10.1136/ard.2009.108282 PMID: 19674980
    • (2010) Annals of the Rheumatic Diseases , vol.69 , pp. 1195-1199
    • Pan, Z.J.1    Maier, S.2    Schwarz, K.3    Azbill, J.4    Akira, S.5    Uematsu, S.6
  • 20
    • 27744444832 scopus 로고    scopus 로고
    • RNA-associated autoantigens activate B cells by combined B cell antigen receptor/Toll-like receptor 7 engagement
    • PMID: 16260486
    • Lau CM, Broughton C, Tabor AS, Akira S, Flavell RA, Mamula MJ et al. RNA-associated autoantigens activate B cells by combined B cell antigen receptor/Toll-like receptor 7 engagement. J Exp Med, 2005; 202:1171-7. PMID: 16260486
    • (2005) J Exp Med , vol.202 , pp. 1171-1177
    • Lau, C.M.1    Broughton, C.2    Tabor, A.S.3    Akira, S.4    Flavell, R.A.5    Mamula, M.J.6
  • 21
    • 84885409854 scopus 로고    scopus 로고
    • IFNalpha Inducible Models of Murine SLE
    • PMID: 24106491
    • Liu Z, Davidson A. IFNalpha Inducible Models of Murine SLE. Front Immunol, 2013; 4:306. doi: 10.3389/fimmu.2013.00306 PMID: 24106491
    • (2013) Front Immunol , vol.4 , pp. 306
    • Liu, Z.1    Davidson, A.2
  • 22
    • 34247891509 scopus 로고    scopus 로고
    • Immunologically active autoantigens: The role of toll-like receptors in the development of chronic inflammatory disease
    • PMID: 17378763
    • Marshak-Rothstein A, Rifkin IR. Immunologically active autoantigens: the role of toll-like receptors in the development of chronic inflammatory disease. Annu Rev Immunol, 2007; 25:419-41. PMID: 17378763
    • (2007) Annu Rev Immunol , vol.25 , pp. 419-441
    • Marshak-Rothstein, A.1    Rifkin, I.R.2
  • 23
    • 0035852650 scopus 로고    scopus 로고
    • The major murine systemic lupus erythematosus susceptibility locus, Sle1, is a cluster of functionally related genes
    • PMID: 11172029
    • Morel L, Blenman K.R., Croker B.P., Wakeland E.K. The major murine systemic lupus erythematosus susceptibility locus, Sle1, is a cluster of functionally related genes. Proc Natl Acad Sci U S A, 2001; 98:1787-92. PMID: 11172029
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 1787-1792
    • Morel, L.1    Blenman, K.R.2    Croker, B.P.3    Wakeland, E.K.4
  • 24
    • 33745617886 scopus 로고    scopus 로고
    • A Tlr7 translocation accelerates systemic autoimmunity in murine lupus
    • PMID: 16777955
    • Subramanian S, Tus K, Li QZ, Wang A, Tian XH, Zhou J et al. A Tlr7 translocation accelerates systemic autoimmunity in murine lupus. Proc Natl Acad Sci U S A, 2006; 103:9970-5. PMID: 16777955
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 9970-9975
    • Subramanian, S.1    Tus, K.2    Li, Q.Z.3    Wang, A.4    Tian, X.H.5    Zhou, J.6
  • 27
    • 36048962438 scopus 로고    scopus 로고
    • Control of toll-like receptor 7 expression is essential to restrict autoimmunity and dendritic cell proliferation
    • PMID: 17997333
    • Deane JA, Pisitkun P, Barrett RS, Feigenbaum L, Town T, Ward JM et al. Control of toll-like receptor 7 expression is essential to restrict autoimmunity and dendritic cell proliferation. Immunity, 2007; 27:801-10. PMID: 17997333
    • (2007) Immunity , vol.27 , pp. 801-810
    • Deane, J.A.1    Pisitkun, P.2    Barrett, R.S.3    Feigenbaum, L.4    Town, T.5    Ward, J.M.6
  • 28
    • 84907409659 scopus 로고    scopus 로고
    • Interleukin-6 Deficiency Corrects Nephritis, Lymphocyte Abnormalities, and Secondary Sjogren's Syndrome Features in Lupus-Prone Sle1.Yaa Mice
    • PMID: 24891301
    • Maier-Moore JS, Horton CG, Mathews SA, Confer AW, Lawrence C, Pan Z et al. Interleukin-6 Deficiency Corrects Nephritis, Lymphocyte Abnormalities, and Secondary Sjogren's Syndrome Features in Lupus-Prone Sle1.Yaa Mice. Arthritis Rheumatol, 2014; 66:2521-31. doi: 10.1002/art.38716 PMID: 24891301
    • (2014) Arthritis Rheumatol , vol.66 , pp. 2521-2531
    • Maier-Moore, J.S.1    Horton, C.G.2    Mathews, S.A.3    Confer, A.W.4    Lawrence, C.5    Pan, Z.6
  • 29
    • 84864859817 scopus 로고    scopus 로고
    • The rationale for BAFF inhibition in systemic lupus erythematosus
    • PMID: 22535567
    • Davidson A. The rationale for BAFF inhibition in systemic lupus erythematosus. Current rheumatology reports, 2012; 14:295-302. doi: 10.1007/s11926-012-0258-2 PMID: 22535567
    • (2012) Current Rheumatology Reports , vol.14 , pp. 295-302
    • Davidson, A.1
  • 30
    • 22244484101 scopus 로고    scopus 로고
    • BAFF overexpression and accelerated glomerular disease in mice with an incomplete genetic predisposition to systemic lupus erythematosus
    • PMID: 15986357
    • Stohl W, Xu D, Kim KS, Koss MN, Jorgensen TN, Deocharan B et al. BAFF overexpression and accelerated glomerular disease in mice with an incomplete genetic predisposition to systemic lupus erythematosus. Arthritis Rheum, 2005; 52:2080-91. PMID: 15986357
    • (2005) Arthritis Rheum , vol.52 , pp. 2080-2091
    • Stohl, W.1    Xu, D.2    Kim, K.S.3    Koss, M.N.4    Jorgensen, T.N.5    Deocharan, B.6
  • 31
    • 77956207524 scopus 로고    scopus 로고
    • In vivo regulation of Bcl6 and T follicular helper cell development
    • PMID: 20519643
    • Poholek AC, Hansen K, Hernandez SG, Eto D, Chandele A, Weinstein JS et al. In vivo regulation of Bcl6 and T follicular helper cell development. J Immunol, 2010; 185:313-26. doi: 10.4049/jimmunol.0904023 PMID: 20519643
    • (2010) J Immunol , vol.185 , pp. 313-326
    • Poholek, A.C.1    Hansen, K.2    Hernandez, S.G.3    Eto, D.4    Chandele, A.5    Weinstein, J.S.6
  • 32
    • 0035892228 scopus 로고    scopus 로고
    • Resolution of three nonproliferative immature splenic B cell subsets reveals multiple selection points during peripheral B cell maturation
    • PMID: 11739500
    • Allman D, Lindsley RC, DeMuth W, Rudd K, Shinton SA, Hardy RR. Resolution of three nonproliferative immature splenic B cell subsets reveals multiple selection points during peripheral B cell maturation. J Immunol, 2001; 167:6834-40. PMID: 11739500
    • (2001) J Immunol , vol.167 , pp. 6834-6840
    • Allman, D.1    Lindsley, R.C.2    DeMuth, W.3    Rudd, K.4    Shinton, S.A.5    Hardy, R.R.6
  • 33
    • 66549091971 scopus 로고    scopus 로고
    • Interleukin-6 aborts lymphopoiesis and elevates production of myeloid cells in systemic lupus erythematosus-prone B6.Sle1.Yaa animals
    • Maeda K, Malykhin A, Teague-Weber BN, Sun XH, Farris AD, Coggeshall KM. Interleukin-6 aborts lymphopoiesis and elevates production of myeloid cells in systemic lupus erythematosus-prone B6.Sle1.Yaa animals. Blood, 2009; 113:4534-40.
    • (2009) Blood , vol.113 , pp. 4534-4540
    • Maeda, K.1    Malykhin, A.2    Teague-Weber, B.N.3    Sun, X.H.4    Farris, A.D.5    Coggeshall, K.M.6
  • 34
    • 84908160577 scopus 로고    scopus 로고
    • STAT1 plays a role in TLR signal transduction and inflammatory responses
    • PMID: 25027037
    • Luu K, Greenhill CJ, Majoros A, Decker T, Jenkins BJ, Mansell A. STAT1 plays a role in TLR signal transduction and inflammatory responses. Immunol Cell Biol, 2014; 92:761-9. doi: 10.1038/icb.2014.51 PMID: 25027037
    • (2014) Immunol Cell Biol , vol.92 , pp. 761-769
    • Luu, K.1    Greenhill, C.J.2    Majoros, A.3    Decker, T.4    Jenkins, B.J.5    Mansell, A.6
  • 35
    • 84857355337 scopus 로고    scopus 로고
    • Possible allelic structure of IgG2a and IgG2c in mice
    • PMID: 22177661
    • Zhang Z, Goldschmidt T, Salter H. Possible allelic structure of IgG2a and IgG2c in mice. Molecular immunology, 2012; 50:169-71. doi: 10.1016/j.molimm.2011.11.006 PMID: 22177661
    • (2012) Molecular Immunology , vol.50 , pp. 169-171
    • Zhang, Z.1    Goldschmidt, T.2    Salter, H.3
  • 36
    • 67749145749 scopus 로고    scopus 로고
    • Type I interferon (IFN)-dependent activation of Mnk1 and its role in the generation of growth inhibitory responses
    • PMID: 19574459
    • Joshi S, Kaur S, Redig AJ, Goldsborough K, David K, Ueda T et al. Type I interferon (IFN)-dependent activation of Mnk1 and its role in the generation of growth inhibitory responses. Proc Natl Acad Sci U S A, 2009; 106:12097-102. doi: 10.1073/pnas.0900562106 PMID: 19574459
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 12097-12102
    • Joshi, S.1    Kaur, S.2    Redig, A.J.3    Goldsborough, K.4    David, K.5    Ueda, T.6
  • 37
    • 78249277326 scopus 로고    scopus 로고
    • Mechanisms of mRNA translation of interferon stimulated genes
    • PMID: 20409730
    • Joshi S, Kaur S, Kroczynska B, Platanias LC. Mechanisms of mRNA translation of interferon stimulated genes. Cytokine, 2010; 52:123-7. doi: 10.1016/j.cyto.2010.03.019 PMID: 20409730
    • (2010) Cytokine , vol.52 , pp. 123-127
    • Joshi, S.1    Kaur, S.2    Kroczynska, B.3    Platanias, L.C.4
  • 38
    • 84871122407 scopus 로고    scopus 로고
    • B Cell TLR7 Expression Drives Anti-RNA Autoantibody Production and Exacerbates Disease in Systemic Lupus Erythematosus-Prone Mice
    • Hwang SH, Lee H, Yamamoto M, Jones LA, Dayalan J, Hopkins R et al. B Cell TLR7 Expression Drives Anti-RNA Autoantibody Production and Exacerbates Disease in Systemic Lupus Erythematosus-Prone Mice. Journal of immunology, 2012; 189:5786-96.
    • (2012) Journal of Immunology , vol.189 , pp. 5786-5796
    • Hwang, S.H.1    Lee, H.2    Yamamoto, M.3    Jones, L.A.4    Dayalan, J.5    Hopkins, R.6
  • 39
    • 41849090456 scopus 로고    scopus 로고
    • IRF9 and STAT1 are required for IgG autoantibody production and B cell expression of TLR7 in mice
    • PMID: 18340381
    • Thibault DL, Chu AD, Graham KL, Balboni I, Lee LY, Kohlmoos C et al. IRF9 and STAT1 are required for IgG autoantibody production and B cell expression of TLR7 in mice. The Journal of clinical investigation, 2008; 118:1417-26. doi: 10.1172/JCI30065 PMID: 18340381
    • (2008) The Journal of Clinical Investigation , vol.118 , pp. 1417-1426
    • Thibault, D.L.1    Chu, A.D.2    Graham, K.L.3    Balboni, I.4    Lee, L.Y.5    Kohlmoos, C.6
  • 40
    • 84860710456 scopus 로고    scopus 로고
    • The Ets-1 transcription factor is required for Stat1-mediated T-bet expression and IgG2a class switching in mouse B cells
    • PMID: 22438254
    • Nguyen HV, Mouly E, Chemin K, Luinaud R, Despres R, Fermand JP et al. The Ets-1 transcription factor is required for Stat1-mediated T-bet expression and IgG2a class switching in mouse B cells. Blood, 2012; 119:4174-81. doi: 10.1182/blood-2011-09-378182 PMID: 22438254
    • (2012) Blood , vol.119 , pp. 4174-4181
    • Nguyen, H.V.1    Mouly, E.2    Chemin, K.3    Luinaud, R.4    Despres, R.5    Fermand, J.P.6
  • 41
    • 84925120155 scopus 로고    scopus 로고
    • Advances in IL-21 biology - Enhancing our understanding of human disease
    • PMID: 25801685
    • Tangye SG. Advances in IL-21 biology - enhancing our understanding of human disease. Curr Opin Immunol, 2015; 34:107-15. doi: 10.1016/j.coi.2015.02.010 PMID: 25801685
    • (2015) Curr Opin Immunol , vol.34 , pp. 107-115
    • Tangye, S.G.1
  • 43
    • 84864133629 scopus 로고    scopus 로고
    • Single and coexpression of CXCR4 and CXCR5 identifies CD4 T helper cells in distinct lymph node niches during influenza virus infection
    • PMID: 22532671
    • Elsner RA, Ernst DN, Baumgarth N. Single and coexpression of CXCR4 and CXCR5 identifies CD4 T helper cells in distinct lymph node niches during influenza virus infection. J Virol, 2012; 86:7146-57. doi: 10.1128/JVI.06904-11 PMID: 22532671
    • (2012) J Virol , vol.86 , pp. 7146-7157
    • Elsner, R.A.1    Ernst, D.N.2    Baumgarth, N.3
  • 44
    • 58149279490 scopus 로고    scopus 로고
    • ICOS-dependent extrafollicular helper T cells elicit IgG production via IL-21 in systemic autoimmunity
    • PMID: 18981236
    • Odegard JM, Marks BR, DiPlacido LD, Poholek AC, Kono DH, Dong C et al. ICOS-dependent extrafollicular helper T cells elicit IgG production via IL-21 in systemic autoimmunity. J Exp Med, 2008; 205:2873-86. doi: 10.1084/jem.20080840 PMID: 18981236
    • (2008) J Exp Med , vol.205 , pp. 2873-2886
    • Odegard, J.M.1    Marks, B.R.2    DiPlacido, L.D.3    Poholek, A.C.4    Kono, D.H.5    Dong, C.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.