메뉴 건너뛰기




Volumn 92, Issue 9, 2014, Pages 761-769

STAT1 plays a role in TLR signal transduction and inflammatory responses

Author keywords

[No Author keywords available]

Indexed keywords

INTERFERON RECEPTOR; INTERFERON REGULATORY FACTOR 3; INTERFERON REGULATORY FACTOR 7; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MYELOID DIFFERENTIATION FACTOR 88; RANTES; STAT1 PROTEIN; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR ADAPTOR MOLECULE 1; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 6; CCL5 PROTEIN, MOUSE; IRF3 PROTEIN, MOUSE; IRF7 PROTEIN, MOUSE; JANUS KINASE; STAT1 PROTEIN, MOUSE; TICAM-1 PROTEIN, MOUSE; TOLL LIKE RECEPTOR; VESICULAR TRANSPORT ADAPTOR PROTEIN;

EID: 84908160577     PISSN: 08189641     EISSN: 14401711     Source Type: Journal    
DOI: 10.1038/icb.2014.51     Document Type: Article
Times cited : (115)

References (31)
  • 1
    • 30044442866 scopus 로고    scopus 로고
    • How toll-like receptors signal: What we know and what we don't know
    • O'Neill LAJ. How Toll-like receptors signal: What we know and what we don't know. Curr Opin Immunol 2006; 18: 3-9.
    • (2006) Curr Opin Immunol , vol.18 , pp. 3-9
    • O'Neill, L.A.J.1
  • 2
    • 32944464648 scopus 로고    scopus 로고
    • Pathogen recognition and innate immunity
    • Akira S, Uematsu S, Takeuchi O. Pathogen recognition and innate immunity. Cell 2006; 124: 783-801.
    • (2006) Cell , vol.124 , pp. 783-801
    • Akira, S.1    Uematsu, S.2    Takeuchi, O.3
  • 3
    • 0043176281 scopus 로고    scopus 로고
    • Role of adaptor trif in the myd88-independent toll-like receptor signaling pathway
    • Yamamoto M, Sato S, Hemmi H, Hoshino K, Kaisho T, Sanjo H e t al. Role of adaptor TRIF in the MyD88-independent Toll-like receptor signaling pathway. Science 2003; 301: 640-643.
    • (2003) Science , vol.301 , pp. 640-643
    • Yamamoto, M.1    Sato, S.2    Hemmi, H.3    Hoshino, K.4    Kaisho, T.5    Sanjo, H.6
  • 4
    • 0042679529 scopus 로고    scopus 로고
    • Identification o f lps2 as a key transducer of myd88-independent tir signalling
    • Hoebe K, Du X, Georgel P, Janssen E, Tabeta K, Kim SO et al. Identification o f Lps2 as a key transducer of MyD88-independent TIR signalling. Nature 2003; 424: 743-748.
    • (2003) Nature , vol.424 , pp. 743-748
    • Hoebe, K.1    Du, X.2    Georgel, P.3    Janssen, E.4    Tabeta, K.5    Kim, S.O.6
  • 5
    • 0141959224 scopus 로고    scopus 로고
    • Lps-tlr4 signalin g to irf-3/7 and nf-kappab involves the toll adapters tram and trif
    • Fitzgerald KA, Rowe DC, Barnes BJ, Caffrey DR, Visintin A, Latz E et al. LPS-TLR4 signalin g to IRF-3/7 and NF-kappaB involves the toll adapters TRAM and TRIF. J Exp Med 2003; 198: 1043-1055.
    • (2003) J Exp Med , vol.198 , pp. 1043-1055
    • Fitzgerald, K.A.1    Rowe, D.C.2    Barnes, B.J.3    Caffrey, D.R.4    Visintin, A.5    Latz, E.6
  • 6
    • 0037451929 scopus 로고    scopus 로고
    • The epidemiology of sepsis in the united states from 1979 through 2000
    • Martin GS, Mannino DM, Eaton S, Moss M. The epidemiology of sepsis in the United States from 1979 through 2000. N Engl J Med 2003; 348: 1546-1554.
    • (2003) N Engl J Med , vol.348 , pp. 1546-1554
    • Martin, G.S.1    Mannino, D.M.2    Eaton, S.3    Moss, M.4
  • 8
    • 84861653061 scopus 로고    scopus 로고
    • Lps hypersensitivity of gp130 mutant mice is independent of elevated haemopoietic tlr4 signaling
    • Greenhill CJ, Gould J, Ernst M, Jarnicki A, Hertzog PJ, Mansell A et al. LPS hypersensitivity of gp130 mutant mice is independent of elevated haemopoietic TLR4 signaling. Immunol Cell Biol 2012; 90: 559-563.
    • (2012) Immunol Cell Biol , vol.90 , pp. 559-563
    • Greenhill, C.J.1    Gould, J.2    Ernst, M.3    Jarnicki, A.4    Hertzog, P.J.5    Mansell, A.6
  • 10
    • 0036796060 scopus 로고    scopus 로고
    • Reciprocal regulation of gastrointestinal homeostasis by shp2 and stat-mediated trefoil gene activation in gp130 mutant mice
    • Tebbutt NC, Giraud AS, Inglese M, Jenkins B, Waring P, Clay FJ et al. Reciprocal regulation of gastrointestinal homeostasis by SHP2 and STAT-mediated trefoil gene activation in gp130 mutant mice. Nat Med 2002; 8: 1089-1097.
    • (2002) Nat Med , vol.8 , pp. 1089-1097
    • Tebbutt, N.C.1    Giraud, A.S.2    Inglese, M.3    Jenkins, B.4    Waring, P.5    Clay, F.J.6
  • 11
    • 43049096401 scopus 로고    scopus 로고
    • Stat3 and stat1 mediate il-11-dependent and inflammation-Associated gastric tumorigenesis in gp130 receptor mutant mice
    • Ernst M, Najdovska M, Grail D, Lundgren-May T, Buchert M, Tye H et al. STAT3 and STAT1 mediate IL-11-dependent and inflammation-Associated gastric tumorigenesis in gp130 receptor mutant mice. J Clin Invest 2008; 118: 1727-1738.
    • (2008) J Clin Invest , vol.118 , pp. 1727-1738
    • Ernst, M.1    Najdovska, M.2    Grail, D.3    Lundgren-May, T.4    Buchert, M.5    Tye, H.6
  • 12
    • 13344282731 scopus 로고    scopus 로고
    • Targeted disruption of the stat1 gene in mice rev eals unexpected physiologic specificity in the jak-stat signaling pathway
    • Meraz MA, White JM, Sheehan KC, Bach EA, Rodig SJ, Dighe AS et al. Targeted disruption of the Stat1 gene in mice rev eals unexpected physiologic specificity in the JAK-STAT signaling pathway. Cell 1996; 84: 431-442.
    • (1996) Cell , vol.84 , pp. 431-442
    • Meraz, M.A.1    White, J.M.2    Sheehan, K.C.3    Bach, E.A.4    Rodig, S.J.5    Dighe, A.S.6
  • 13
    • 0035067108 scopus 로고    scopus 로고
    • Requirement for stat1 in lps-induced gene expression in macrophages
    • Ohmori Y, Hamilton TA. Requirement for STAT1 in LPS-induced gene expression in macrophages. J Leukoc Biol 2001; 69: 598-604.
    • (2001) J Leukoc Biol , vol.69 , pp. 598-604
    • Ohmori, Y.1    Hamilton, T.A.2
  • 14
    • 0346792731 scopus 로고    scopus 로고
    • Phosphorylation of the stat1 transactivation domain is required for full-fledged ifngamma-dependent innate immunity
    • Varinou L, Ramsauer K, Karaghiosoff M, Kolbe T, Pfeffer K, Muller M et al. Phosphorylation of the Stat1 transactivation domain is required for full-fledged IFNgamma-dependent innate immunity. Immunity 2003; 19: 793-802.
    • (2003) Immunity , vol.19 , pp. 793-802
    • Varinou, L.1    Ramsauer, K.2    Karaghiosoff, M.3    Kolbe, T.4    Pfeffer, K.5    Muller, M.6
  • 15
    • 0038605053 scopus 로고    scopus 로고
    • Toll-like receptors 2 and 4 activate stat1 serine phosphorylation by distinct mechanisms in macrophages
    • Rhee SH, Jones BW, Toshchakov V, Vogel SN, Fenton MJ. Toll-like receptors 2 and 4 activate STAT1 serine phosphorylation by distinct mechanisms in macrophages. J Biol Chem 2003; 278: 22506-22512.
    • (2003) J Biol Chem , vol.278 , pp. 22506-22512
    • Rhee, S.H.1    Jones, B.W.2    Toshchakov, V.3    Vogel, S.N.4    Fenton, M.J.5
  • 16
    • 35748939086 scopus 로고    scopus 로고
    • Differential effects of cpg dna on ifn-bet a induction and stat1 activation in murine macrophages versus dendritic cells: Alternatively activated stat1 negatively regulates tlr signaling in macrophages
    • Schroder K, Spille M, Pilz A, Lattin J, Bode KA, Irvine KM et al. Differential effects of CpG DNA on IFN-bet a induction and STAT1 activation in murine macrophages versus dendritic cells: alternatively activated STAT1 negatively regulates TLR signaling in macrophages. J Immunol 2007; 179: 3495-3503.
    • (2007) J Immunol , vol.179 , pp. 3495-3503
    • Schroder, K.1    Spille, M.2    Pilz, A.3    Lattin, J.4    Bode, K.A.5    Irvine, K.M.6
  • 17
    • 47849097202 scopus 로고    scopus 로고
    • Silica crystals and aluminum salts activate the nalp3 inflammasome through phagosomal destabilization
    • Hornung V, Ba uernfeind F, Halle A, Samstad EO, Kono H, Rock KL et al. Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization. Nat Immunol 2008; 9: 847-856.
    • (2008) Nat Immunol , vol.9 , pp. 847-856
    • Hornung, V.1    Bauernfeind, F.2    Halle, A.3    Samstad, E.O.4    Kono, H.5    Rock, K.L.6
  • 18
    • 0038637936 scopus 로고    scopus 로고
    • Irakdependent phosphorylation of stat1 on serine 727 in response to interleukin-1 and effects on gene expression
    • Nguyen H, Chatterjee-Kishore M, Jiang Z, Qing Y, Ramana CV, Bayes J et al. IRAKdependent phosphorylation of Stat1 on serine 727 in response to interleukin-1 and effects on gene expression. J Interferon Cytokine Res 2003; 23: 183-192.
    • (2003) J Interferon Cytokine Res , vol.23 , pp. 183-192
    • Nguyen, H.1    Chatterjee-Kishore, M.2    Jiang, Z.3    Qing, Y.4    Ramana, C.V.5    Bayes, J.6
  • 19
    • 0032869581 scopus 로고    scopus 로고
    • Transcription factor activity of stat proteins: Structural requirements and regulation by phosphorylation and interacting proteins
    • Decker T, Kovarik P. Transcription factor activity of STAT proteins: structural requirements and regulation by phosphorylation and interacting proteins. Cell Mol Life Sci 1999; 55: 1535-1546.
    • (1999) Cell Mol Life Sci , vol.55 , pp. 1535-1546
    • Decker, T.1    Kovarik, P.2
  • 20
    • 0034658024 scopus 로고    scopus 로고
    • Serine phosphorylation of stats
    • Decker T, Kovarik P. Serine phosphorylation of STATs. Oncogene 2000; 19: 2628-2637.
    • (2000) Oncogene , vol.19 , pp. 2628-2637
    • Decker, T.1    Kovarik, P.2
  • 21
    • 0347065364 scopus 로고    scopus 로고
    • Interferon regulatory factor-3-mediated activation of the interferon-sensitive response element by toll-like receptor (tlr) 4 but not tlr3 requires the p65 subunit of nf-kappa
    • Wietek C,Miggin SM,Jefferies CA,O'Neill LA. Interferon regulatory factor-3-mediated activation of the interferon-sensitive response element by Toll-like receptor (TLR) 4 but not TLR3 requires the p65 subunit of NF-kappa J Biol Chem 2003, 278, 50923-50931.
    • (2003) J Biol Chem , vol.278 , pp. 50923-50931
    • Wietek, C.1    Miggin, S.M.2    Jefferies, C.A.3    O'Neill, L.A.4
  • 22
    • 0037114185 scopus 로고    scopus 로고
    • Cutting edge: A novel toll/il-1 receptor domain-containing adapter that preferentially activates the ifn-beta promoter in the toll-like receptor signaling
    • Yamamoto M, Sato S, Mori K, Hoshino K, Takeuchi O, Takeda K et al. Cutting edge: a novel Toll/IL-1 receptor domain-containing adapter that preferentially activates the IFN-beta promoter in the Toll-like receptor signaling. J Immunol 2002; 169: 6668-6672.
    • (2002) J Immunol , vol.169 , pp. 6668-6672
    • Yamamoto, M.1    Sato, S.2    Mori, K.3    Hoshino, K.4    Takeuchi, O.5    Takeda, K.6
  • 23
    • 4444258208 scopus 로고    scopus 로고
    • Mal interacts with tumor necrosis factor receptor-Associated factor (traf)-6 to mediate nf-kappab acti vation by toll-like receptor (tlr)-2 and tlr4
    • Mansell A, Brint E, Gould JA, O'Neill LA, Hertzog PJ. Mal interacts with tumor necrosis factor receptor-Associated factor (TRAF)-6 to mediate NF-kappaB acti vation by toll-like receptor (TLR)-2 and TLR4. J Biol Chem 2004; 279: 37227-37230.
    • (2004) J Biol Chem , vol.279 , pp. 37227-37230
    • Mansell, A.1    Brint, E.2    Gould, J.A.3    O'Neill, L.A.4    Hertzog, P.J.5
  • 24
    • 69949183194 scopus 로고    scopus 로고
    • Myd88 adapter-like (mal)/tirap interaction with traf6 is critical for tlr2-And tlr4-mediated nf-kappab proinflammatory responses
    • Verstak B, Nagpal K, Bottomley SP, Golenbock DT, Hertzog PJ, M ansell A. MyD88 adapter-like (Mal)/TIRAP interaction with TRAF6 is critical for TLR2-And TLR4-mediated NF-kappaB proinflammatory responses. J Biol Chem 2009; 284: 24192-24203.
    • (2009) J Biol Chem , vol.284 , pp. 24192-24203
    • Verstak, B.1    Nagpal, K.2    Bottomley, S.P.3    Golenbock, D.T.4    Hertzog, P.J.5    Mansell, A.6
  • 25
    • 0141923690 scopus 로고    scopus 로고
    • Toll/il-1 receptor domain-containing adaptor inducing ifn-beta (trif) associates with tnf receptor-Associated factor 6 and tank-binding kinase 1, and activates two distinct transcripti on factors, nf-kappa b and ifn-regulatory factor-3, in the toll-like receptor signaling
    • Sato S, Sugiyama M, Yamamoto M, Watanabe Y, Kawai T, Takeda K et al. Toll/IL-1 receptor domain-containing adaptor inducing IFN-beta (TRIF) associates with TNF receptor-Associated factor 6 and TANK-binding kinase 1, and activates two distinct transcripti on factors, NF-kappa B and IFN-regulatory factor-3, in the Toll-like receptor signaling. J Immunol 2003; 171: 4304-4310.
    • (2003) J Immunol , vol.171 , pp. 4304-4310
    • Sato, S.1    Sugiyama, M.2    Yamamoto, M.3    Watanabe, Y.4    Kawai, T.5    Takeda, K.6
  • 26
    • 0030772458 scopus 로고    scopus 로고
    • Stat3 serine phosphorylation by erkdependent and-independent pathways negatively modulates its tyrosine phosphorylation
    • Chung J, Uchida E, Grammer TC, Blenis J. STAT3 serine phosphorylation by ERKdependent and-independent pathways negatively modulates its tyrosine phosphorylation. Mol Cell Biol 1997; 17: 6508-6516.
    • (1997) Mol Cell Biol , vol.17 , pp. 6508-6516
    • Chung, J.1    Uchida, E.2    Grammer, T.C.3    Blenis, J.4
  • 27
    • 31344467156 scopus 로고    scopus 로고
    • Suppressor of cytokine signaling 1 negatively regulates toll-like receptor signaling by mediating mal degradation
    • Mansell A, Smith R, Doyle SL, Gray P, Fenner JE, Crack PJ e t al. Suppressor of cytokine signaling 1 negatively regulates Toll-like receptor signaling by mediating Mal degradation. Nat Immunol 2006; 7: 148-155.
    • (2006) Nat Immunol , vol.7 , pp. 148-155
    • Mansell, A.1    Smith, R.2    Doyle, S.L.3    Gray, P.4    Fenner, J.E.5    Crack, P.J.6
  • 28
    • 23844445451 scopus 로고    scopus 로고
    • Hyperactivation of stat3 in gp130 mutant mice promotes gastric hyperproliferation and desensitizes tgfbeta signaling
    • Jenkins BJ, Grail D, Nheu T, Najdovska M, Wang B, Waring P et al. Hyperactivation of Stat3 in gp130 mutant mice promotes gastric hyperproliferation and desensitizes TGFbeta signaling. Nat Med 2005; 11: 845-852.
    • (2005) Nat Med , vol.11 , pp. 845-852
    • Jenkins, B.J.1    Grail, D.2    Nheu, T.3    Najdovska, M.4    Wang, B.5    Waring, P.6
  • 29
    • 0034662239 scopus 로고    scopus 로고
    • Cutting edge: Repurification of lipopolysaccharide eliminates signaling through both human and murine toll-like receptor 2
    • Hirschfeld M, Ma Y , Weis JH, Vogel SN, Weis JJ. Cutting edge: repurification of lipopolysaccharide eliminates signaling through both human and murine toll-like receptor 2. J Immunol 2000; 165: 618-622.
    • (2000) J Immunol , vol.165 , pp. 618-622
    • Hirschfeld, M.1    Ma, Y.2    Weis, J.H.3    Vogel, S.N.4    Weis, J.J.5
  • 31
    • 0035336425 scopus 로고    scopus 로고
    • A novel pathway regulating lipopolysaccharide-induced shock by st2/t1 via inhibition of toll-like receptor 4 expression
    • Sweet MJ, Leung BP, Kang D, Sogaard M, Schulz K, Trajkovic V et al. A novel pathway regulating lipopolysaccharide-induced shock by ST2/T1 via inhibition of Toll-like receptor 4 expression. J Immunol 2001; 16 6: 6633-6639.
    • (2001) J Immunol , vol.166 , pp. 6633-6639
    • Sweet, M.J.1    Leung, B.P.2    Kang, D.3    Sogaard, M.4    Schulz, K.5    Trajkovic, V.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.