-
1
-
-
84885706493
-
Comparative evolutionary genomics of the STAT family of transcription factors
-
Wang, Y., and D. E. Levy. 2012. Comparative evolutionary genomics of the STAT family of transcription factors. JAK-STAT 1: 23-33.
-
(2012)
JAK-STAT
, vol.1
, pp. 23-33
-
-
Wang, Y.1
Levy, D.E.2
-
2
-
-
84859992161
-
The JAK-STAT pathway at twenty
-
Stark, G. R., and J. E. Darnell, Jr. 2012. The JAK-STAT pathway at twenty. Immunity 36: 503-514.
-
(2012)
Immunity
, vol.36
, pp. 503-514
-
-
Stark, G.R.1
Darnell, J.E.2
-
3
-
-
84900432315
-
Mechanism of activation of protein kinase JAK2 by the growth hormone receptor
-
Brooks, A. J., W. Dai, M. L. O'Mara, D. Abankwa, Y. Chhabra, R. A. Pelekanos, O. Gardon, K. A. Tunny, K. M. Blucher, C. J. Morton, et al. 2014. Mechanism of activation of protein kinase JAK2 by the growth hormone receptor. Science 344: 1249783.
-
(2014)
Science
, vol.344
, pp. 1249783
-
-
Brooks, A.J.1
Dai, W.2
O'Mara, M.L.3
Abankwa, D.4
Chhabra, Y.5
Pelekanos, R.A.6
Gardon, O.7
Tunny, K.A.8
Blucher, K.M.9
Morton, C.J.10
-
4
-
-
41549107522
-
Cytokine signaling modules in inflammatory responses
-
O'Shea, J. J., and P. J. Murray. 2008. Cytokine signaling modules in inflammatory responses. Immunity 28: 477-487.
-
(2008)
Immunity
, vol.28
, pp. 477-487
-
-
O'Shea, J.J.1
Murray, P.J.2
-
5
-
-
0030469719
-
Activation of STAT4 by IL-12 and IFN-Alpha: Evidence for the involvement of ligand-induced tyrosine and serine phosphorylation
-
Cho, S. S., C. M. Bacon, C. Sudarshan, R. C. Rees, D. Finbloom, R. Pine, and J. J. O'Shea. 1996. Activation of STAT4 by IL-12 and IFN-Alpha: Evidence for the involvement of ligand-induced tyrosine and serine phosphorylation. J. Immunol. 157: 4781-4789.
-
(1996)
J. Immunol
, vol.157
, pp. 4781-4789
-
-
Cho, S.S.1
Bacon, C.M.2
Sudarshan, C.3
Rees, R.C.4
Finbloom, D.5
Pine, R.6
O'Shea, J.J.7
-
6
-
-
0345570521
-
The IL-27R (WSX-1) is required to suppress T cell hyperactivity during infection
-
Villarino, A., L. Hibbert, L. Lieberman, E. Wilson, T. Mak, H. Yoshida, R. A. Kastelein, C. Saris, and C. A. Hunter. 2003. The IL-27R (WSX-1) is required to suppress T cell hyperactivity during infection. Immunity 19: 645-655.
-
(2003)
Immunity
, vol.19
, pp. 645-655
-
-
Villarino, A.1
Hibbert, L.2
Lieberman, L.3
Wilson, E.4
Mak, T.5
Yoshida, H.6
Kastelein, R.A.7
Saris, C.8
Hunter, C.A.9
-
7
-
-
0028937707
-
Spacing of palindromic half sites as a determinant of selective STAT (signal transducers and activators of transcription) DNA binding and transcriptional activity
-
Seidel, H. M., L. H. Milocco, P. Lamb, J. E. Darnell, Jr., R. B. Stein, and J. Rosen. 1995. Spacing of palindromic half sites as a determinant of selective STAT (signal transducers and activators of transcription) DNA binding and transcriptional activity. Proc. Natl. Acad. Sci. USA 92: 3041-3045.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 3041-3045
-
-
Seidel, H.M.1
Milocco, L.H.2
Lamb, P.3
Darnell, J.E.4
Stein, R.B.5
Rosen, J.6
-
8
-
-
79953134246
-
Genomic views of STAT function in CD4+ T helper cell differentiation
-
O'Shea, J. J., R. Lahesmaa, G. Vahedi, A. Laurence, and Y. Kanno. 2011. Genomic views of STAT function in CD4+ T helper cell differentiation. Nat. Rev. Immunol. 11: 239-250.
-
(2011)
Nat. Rev. Immunol
, vol.11
, pp. 239-250
-
-
O'Shea, J.J.1
Lahesmaa, R.2
Vahedi, G.3
Laurence, A.4
Kanno, Y.5
-
9
-
-
34547633677
-
Genome-wide profiles of STAT1 DNA association using chromatin immunoprecipitation and massively parallel sequencing
-
Robertson, G., M. Hirst, M. Bainbridge, M. Bilenky, Y. Zhao, T. Zeng, G. Euskirchen, B. Bernier, R. Varhol, A. Delaney, et al. 2007. Genome-wide profiles of STAT1 DNA association using chromatin immunoprecipitation and massively parallel sequencing. Nat. Methods 4: 651-657.
-
(2007)
Nat. Methods
, vol.4
, pp. 651-657
-
-
Robertson, G.1
Hirst, M.2
Bainbridge, M.3
Bilenky, M.4
Zhao, Y.5
Zeng, T.6
Euskirchen, G.7
Bernier, B.8
Varhol, R.9
Delaney, A.10
-
10
-
-
84859401055
-
Transcriptional and epigenetic control of T helper cell specification: Molecular mechanisms underlying commitment and plasticity
-
Kanno, Y., G. Vahedi, K. Hirahara, K. Singleton, and J. J. O'Shea. 2012. Transcriptional and epigenetic control of T helper cell specification: Molecular mechanisms underlying commitment and plasticity. Annu. Rev. Immunol. 30: 707-731.
-
(2012)
Annu. Rev. Immunol
, vol.30
, pp. 707-731
-
-
Kanno, Y.1
Vahedi, G.2
Hirahara, K.3
Singleton, K.4
O'Shea, J.J.5
-
11
-
-
84863843763
-
The Stat3/GR interaction code: Predictive value of direct/indirect DNA recruitment for transcription outcome
-
Langlais, D., C. Couture, A. Balsalobre, and J. Drouin. 2012. The Stat3/GR interaction code: Predictive value of direct/indirect DNA recruitment for transcription outcome. Mol. Cell 47: 38-49.
-
(2012)
Mol. Cell
, vol.47
, pp. 38-49
-
-
Langlais, D.1
Couture, C.2
Balsalobre, A.3
Drouin, J.4
-
12
-
-
77953917067
-
Discrete roles of STAT4 and STAT6 transcription factors in tuning epigenetic modifications and transcription during T helper cell differentiation
-
Wei, L., G. Vahedi, H.-W. Sun, W. T. Watford, H. Takatori, H. L. Ramos, H. Takahashi, J. Liang, G. Gutierrez-Cruz, C. Zang, et al. 2010. Discrete roles of STAT4 and STAT6 transcription factors in tuning epigenetic modifications and transcription during T helper cell differentiation. Immunity 32: 840-851.
-
(2010)
Immunity
, vol.32
, pp. 840-851
-
-
Wei, L.1
Vahedi, G.2
Sun, H.-W.3
Watford, W.T.4
Takatori, H.5
Ramos, H.L.6
Takahashi, H.7
Liang, J.8
Zang, C.9
-
13
-
-
84861563048
-
Genome-wide analyses reveal the extent of opportunistic STAT5 binding that does not yield transcriptional activation of neighboring genes
-
Zhu, B. M., K. Kang, J. H. Yu, W. Chen, H. E. Smith, D. Lee, H. W. Sun, L. Wei, and L. Hennighausen. 2012. Genome-wide analyses reveal the extent of opportunistic STAT5 binding that does not yield transcriptional activation of neighboring genes. Nucleic Acids Res. 40: 4461-4472.
-
(2012)
Nucleic Acids Res
, vol.40
, pp. 4461-4472
-
-
Zhu, B.M.1
Kang, K.2
Yu, J.H.3
Chen, W.4
Smith, H.E.5
Lee, D.6
Sun, H.W.7
Wei, L.8
Hennighausen, L.9
-
14
-
-
84872178910
-
Comprehensive metaanalysis of Signal Transducers and Activators of Transcription (STAT) genomic binding patterns discerns cell-specific cis-regulatory modules
-
Kang, K., G. W. Robinson, and L. Hennighausen. 2013. Comprehensive metaanalysis of Signal Transducers and Activators of Transcription (STAT) genomic binding patterns discerns cell-specific cis-regulatory modules. BMC Genomics 14: 4.
-
(2013)
BMC Genomics
, vol.14
, pp. 4
-
-
Kang, K.1
Robinson, G.W.2
Hennighausen, L.3
-
15
-
-
0030936627
-
GAS elements: A few nucleotides with a major impact on cytokine-induced gene expression
-
Decker, T., P. Kovarik, and A. Meinke. 1997. GAS elements: A few nucleotides with a major impact on cytokine-induced gene expression. J. Interferon Cytokine Res. 17: 121-134.
-
(1997)
J. Interferon Cytokine Res
, vol.17
, pp. 121-134
-
-
Decker, T.1
Kovarik, P.2
Meinke, A.3
-
16
-
-
84880677334
-
STAT5 outcompetes STAT3 to regulate the expression of the oncogenic transcriptional modulator BCL6
-
Walker, S. R., E. A. Nelson, J. E. Yeh, L. Pinello, G. C. Yuan, and D. A. Frank. 2013. STAT5 outcompetes STAT3 to regulate the expression of the oncogenic transcriptional modulator BCL6. Mol. Cell. Biol. 33: 2879-2890.
-
(2013)
Mol. Cell. Biol
, vol.33
, pp. 2879-2890
-
-
Walker, S.R.1
Nelson, E.A.2
Yeh, J.E.3
Pinello, L.4
Yuan, G.C.5
Frank, D.A.6
-
17
-
-
84875505809
-
The cytokines IL-21 and GM-CSF have opposing regulatory roles in the apoptosis of conventional dendritic cells
-
Wan, C.-K., J. Oh, P. Li, E. E. West, E. A. Wong, A. B. Andraski, R. Spolski, Z.-X. Yu, J. He, B. L. Kelsall, and W. J. Leonard. 2013. The cytokines IL-21 and GM-CSF have opposing regulatory roles in the apoptosis of conventional dendritic cells. Immunity 38: 514-527.
-
(2013)
Immunity
, vol.38
, pp. 514-527
-
-
Wan, C.-K.1
Oh, J.2
Li, P.3
West, E.E.4
Wong, E.A.5
Andraski, A.B.6
Spolski, R.7
Yu, Z.-X.8
He, J.9
Kelsall, B.L.10
Leonard, W.J.11
-
18
-
-
79951682333
-
Opposing regulation of the locus encoding IL-17 through direct, reciprocal actions of STAT3 and STAT5
-
Yang, X.-P., K. Ghoreschi, S. M. Steward-Tharp, J. Rodriguez-Canales, J. Zhu, J. R. Grainger, K. Hirahara, H.-W. Sun, L. Wei, G. Vahedi, et al. 2011. Opposing regulation of the locus encoding IL-17 through direct, reciprocal actions of STAT3 and STAT5. Nat. Immunol. 12: 247-254.
-
(2011)
Nat. Immunol
, vol.12
, pp. 247-254
-
-
Yang, X.-P.1
Ghoreschi, K.2
Steward-Tharp, S.M.3
Zhu, J.4
Grainger, J.R.5
Hirahara, K.6
Sun, H.-W.7
Wei, L.8
Vahedi, G.9
-
19
-
-
84896647364
-
A role for the ITAM signaling module in specifying cytokine-receptor functions
-
Bezbradica, J. S., R. K. Rosenstein, R. A. DeMarco, I. Brodsky, and R. Medzhitov. 2014. A role for the ITAM signaling module in specifying cytokine-receptor functions. Nat. Immunol. 15: 333-342.
-
(2014)
Nat. Immunol
, vol.15
, pp. 333-342
-
-
Bezbradica, J.S.1
Rosenstein, R.K.2
DeMarco, R.A.3
Brodsky, I.4
Medzhitov, R.5
-
20
-
-
84899477789
-
The adaptor TRAF5 limits the differentiation of inflammatory CD4(+) T cells by antagonizing signaling via the receptor for IL-6
-
Nagashima, H., Y. Okuyama, A. Asao, T. Kawabe, S. Yamaki, H. Nakano, M. Croft, N. Ishii, and T. So. 2014. The adaptor TRAF5 limits the differentiation of inflammatory CD4(+) T cells by antagonizing signaling via the receptor for IL-6. Nat. Immunol. 15: 449-456.
-
(2014)
Nat. Immunol
, vol.15
, pp. 449-456
-
-
Nagashima, H.1
Okuyama, Y.2
Asao, A.3
Kawabe, T.4
Yamaki, S.5
Nakano, H.6
Croft, M.7
Ishii, N.8
So, T.9
-
21
-
-
78650304236
-
Charting histone modifications and the functional organization of mammalian genomes
-
Zhou, V. W., A. Goren, and B. E. Bernstein. 2011. Charting histone modifications and the functional organization of mammalian genomes. Nat. Rev. Genet. 12: 7-18.
-
(2011)
Nat. Rev. Genet
, vol.12
, pp. 7-18
-
-
Zhou, V.W.1
Goren, A.2
Bernstein, B.E.3
-
22
-
-
58849092225
-
Epigenetic control of T-helpercell differentiation
-
Wilson, C. B., E. Rowell, and M. Sekimata. 2009. Epigenetic control of T-helpercell differentiation. Nat. Rev. Immunol. 9: 91-105.
-
(2009)
Nat. Rev. Immunol
, vol.9
, pp. 91-105
-
-
Wilson, C.B.1
Rowell, E.2
Sekimata, M.3
-
23
-
-
81255154496
-
Epigenetic repression of the Igk locus by STAT5-mediated recruitment of the histone methyltransferase Ezh2
-
Mandal, M., S. E. Powers, M. Maienschein-Cline, E. T. Bartom, K. M. Hamel, B. L. Kee, A. R. Dinner, and M. R. Clark. 2011. Epigenetic repression of the Igk locus by STAT5-mediated recruitment of the histone methyltransferase Ezh2. Nat. Immunol. 12: 1212-1220.
-
(2011)
Nat. Immunol
, vol.12
, pp. 1212-1220
-
-
Mandal, M.1
Powers, S.E.2
Bartom, E.T.3
Hamel, K.M.4
Kee, B.L.5
Dinner, A.R.6
Clark, M.R.7
-
24
-
-
44649117905
-
Integration of external signaling pathways with the core transcriptional network in embryonic stem cells
-
Chen, X., H. Xu, P. Yuan, F. Fang, M. Huss, V. B. Vega, E. Wong, Y. L. Orlov, W. Zhang, J. Jiang, et al. 2008. Integration of external signaling pathways with the core transcriptional network in embryonic stem cells. Cell 133: 1106-1117.
-
(2008)
Cell
, vol.133
, pp. 1106-1117
-
-
Chen, X.1
Xu, H.2
Yuan, P.3
Fang, F.4
Huss, M.5
Vega, V.B.6
Wong, E.7
Orlov, Y.L.8
Zhang, W.9
Jiang, J.10
-
25
-
-
84867581744
-
A validated regulatory network for Th17 cell specification
-
Ciofani, M., A. Madar, C. Galan, M. Sellars, K. Mace, F. Pauli, A. Agarwal, W. Huang, C. N. Parkurst, M. Muratet, et al. 2012. A validated regulatory network for Th17 cell specification. Cell 151: 289-303.
-
(2012)
Cell
, vol.151
, pp. 289-303
-
-
Ciofani, M.1
Madar, A.2
Galan, C.3
Sellars, M.4
Mace, K.5
Pauli, F.6
Agarwal, A.7
Huang, W.8
Parkurst, C.N.9
Muratet, M.10
-
26
-
-
77954917130
-
Nonconventional initiation complex assembly by STAT and NF-kappaB transcription factors regulates nitric oxide synthase expression
-
Farlik, M., B. Reutterer, C. Schindler, F. Greten, C. Vogl, M. Muller, and T. Decker. 2010. Nonconventional initiation complex assembly by STAT and NF-kappaB transcription factors regulates nitric oxide synthase expression. Immunity 33: 25-34.
-
(2010)
Immunity
, vol.33
, pp. 25-34
-
-
Farlik, M.1
Reutterer, B.2
Schindler, C.3
Greten, F.4
Vogl, C.5
Muller, M.6
Decker, T.7
-
27
-
-
0032579292
-
Transcription factorspecific requirements for coactivators and their acetyltransferase functions
-
Korzus, E., J. Torchia, D. W. Rose, L. Xu, R. Kurokawa, E. M. McInerney, T. M. Mullen, C. K. Glass, and M. G. Rosenfeld. 1998. Transcription factorspecific requirements for coactivators and their acetyltransferase functions. Science 279: 703-707.
-
(1998)
Science
, vol.279
, pp. 703-707
-
-
Korzus, E.1
Torchia, J.2
Rose, D.W.3
Xu, L.4
Kurokawa, R.5
McInerney, E.M.6
Mullen, T.M.7
Glass, C.K.8
Rosenfeld, M.G.9
-
28
-
-
84884355522
-
Synergistic activation of inflammatory cytokine genes by interferon-g-induced chromatin remodeling and toll-like receptor signaling
-
Qiao, Y., E. G. Giannopoulou, C. H. Chan, S.-H. Park, S. Gong, J. Chen, X. Hu, O. Elemento, and L. B. Ivashkiv. 2013. Synergistic activation of inflammatory cytokine genes by interferon-g-induced chromatin remodeling and toll-like receptor signaling. Immunity 39: 454-469.
-
(2013)
Immunity
, vol.39
, pp. 454-469
-
-
Qiao, Y.1
Giannopoulou, E.G.2
Chan, C.H.3
Park, S.-H.4
Gong, S.5
Chen, J.6
Hu, X.7
Elemento, O.8
Ivashkiv, L.B.9
-
29
-
-
71749089605
-
Analysis of interleukin-21-induced Prdm1 gene regulation reveals functional cooperation of STAT3 and IRF4 transcription factors
-
Kwon, H., D. Thierry-Mieg, J. Thierry-Mieg, H. P. Kim, J. Oh, C. Tunyaplin, S. Carotta, C. E. Donovan, M. L. Goldman, P. Tailor, et al. 2009. Analysis of interleukin-21-induced Prdm1 gene regulation reveals functional cooperation of STAT3 and IRF4 transcription factors. Immunity 31: 941-952.
-
(2009)
Immunity
, vol.31
, pp. 941-952
-
-
Kwon, H.1
Kim, H.P.2
Oh, J.3
Tunyaplin, C.4
Carotta, S.5
Donovan, C.E.6
Goldman, M.L.7
Tailor, P.8
-
30
-
-
77954928774
-
Maintaining cell identity through global control of genomic organization
-
Natoli, G. 2010. Maintaining cell identity through global control of genomic organization. Immunity 33: 12-24.
-
(2010)
Immunity
, vol.33
, pp. 12-24
-
-
Natoli, G.1
-
31
-
-
84888015137
-
Super-enhancers in the control of cell identity and disease
-
Hnisz, D., B. J. Abraham, T. I. Lee, A. Lau, V. Saint-André, A. A. Sigova, H. A. Hoke, and R. A. Young. 2013. Super-enhancers in the control of cell identity and disease. Cell 155: 934-947.
-
(2013)
Cell
, vol.155
, pp. 934-947
-
-
Hnisz, D.1
Abraham, B.J.2
Lee, T.I.3
Lau, A.4
Sigova, A.A.5
Hoke, H.A.6
Young, R.A.7
-
32
-
-
84887072795
-
Chromatin stretch enhancer states drive cell-specific gene regulation and harbor human disease risk variants
-
NISC Comparative Sequencing Program.; National Institutes of Health Intramural Sequencing Center Comparative Sequencing Program Authors.; NISC Comparative Sequencing Program Authors
-
Parker, S. C., M. L. Stitzel, D. L. Taylor, J. M. Orozco, M. R. Erdos, J. A. Akiyama, K. L. van Bueren, P. S. Chines, N. Narisu, B. L. Black, et al.; NISC Comparative Sequencing Program.; National Institutes of Health Intramural Sequencing Center Comparative Sequencing Program Authors.; NISC Comparative Sequencing Program Authors. 2013. Chromatin stretch enhancer states drive cell-specific gene regulation and harbor human disease risk variants. Proc. Natl. Acad. Sci. USA 110: 17921-17926.
-
(2013)
Proc. Natl. Acad. Sci. USA
, vol.110
, pp. 17921-17926
-
-
Parker, S.C.1
Stitzel, M.L.2
Taylor, D.L.3
Orozco, J.M.4
Erdos, M.R.5
Akiyama, J.A.6
Van Bueren, K.L.7
Chines, P.S.8
Narisu, N.9
Black, B.L.10
-
33
-
-
84870027825
-
STATs shape the active enhancer landscape of T cell populations
-
Vahedi, G., H. Takahashi, S. Nakayamada, H.-W. Sun, V. Sartorelli, Y. Kanno, and J. J. O'Shea. 2012. STATs shape the active enhancer landscape of T cell populations. Cell 151: 981-993.
-
(2012)
Cell
, vol.151
, pp. 981-993
-
-
Vahedi, G.1
Takahashi, H.2
Nakayamada, S.3
Sun, H.-W.4
Sartorelli, V.5
Kanno, Y.6
O'Shea, J.J.7
-
34
-
-
84886724189
-
Expression and regulation of intergenic long noncoding RNAs during T cell development and differentiation
-
Hu, G., Q. Tang, S. Sharma, F. Yu, T. M. Escobar, S. A. Muljo, J. Zhu, and K. Zhao. 2013. Expression and regulation of intergenic long noncoding RNAs during T cell development and differentiation. Nat. Immunol. 14: 1190-1198.
-
(2013)
Nat. Immunol
, vol.14
, pp. 1190-1198
-
-
Hu, G.1
Tang, Q.2
Sharma, S.3
Yu, F.4
Escobar, T.M.5
Muljo, S.A.6
Zhu, J.7
Zhao, K.8
-
35
-
-
77953915915
-
Regulation of microRNA expression and abundance during lymphopoiesis
-
Kuchen, S., W. Resch, A. Yamane, N. Kuo, Z. Li, T. Chakraborty, L. Wei, A. Laurence, T. Yasuda, S. Peng, et al. 2010. Regulation of microRNA expression and abundance during lymphopoiesis. Immunity 32: 828-839.
-
(2010)
Immunity
, vol.32
, pp. 828-839
-
-
Kuchen, S.1
Resch, W.2
Yamane, A.3
Kuo, N.4
Li, Z.5
Chakraborty, T.6
Wei, L.7
Laurence, A.8
Yasuda, T.9
Peng, S.10
-
36
-
-
84865425772
-
Cutting edge: Influence of Tmevpg1, a long intergenic noncoding RNA, on the expression of Ifng by Th1 cells
-
Collier, S. P., P. L. Collins, C. L. Williams, M. R. Boothby, and T. M. Aune. 2012. Cutting edge: Influence of Tmevpg1, a long intergenic noncoding RNA, on the expression of Ifng by Th1 cells. J. Immunol. 189: 2084-2088.
-
(2012)
J. Immunol
, vol.189
, pp. 2084-2088
-
-
Collier, S.P.1
Collins, P.L.2
Williams, C.L.3
Boothby, M.R.4
Aune, T.M.5
-
37
-
-
84874025014
-
The NeST long ncRNA controls microbial susceptibility and epigenetic activation of the interferong locus
-
Gomez, J. A., O. L. Wapinski, Y. W. Yang, J. F. Bureau, S. Gopinath, D. M. Monack, H. Y. Chang, M. Brahic, and K. Kirkegaard. 2013. The NeST long ncRNA controls microbial susceptibility and epigenetic activation of the interferong locus. Cell 152: 743-754.
-
(2013)
Cell
, vol.152
, pp. 743-754
-
-
Gomez, J.A.1
Wapinski, O.L.2
Yang, Y.W.3
Bureau, J.F.4
Gopinath, S.5
Monack, D.M.6
Chang, H.Y.7
Brahic, M.8
Kirkegaard, K.9
-
39
-
-
84899486799
-
The STAT3-binding long noncoding RNA lnc-DC controls human dendritic cell differentiation
-
Wang, P., Y. Xue, Y. Han, L. Lin, C. Wu, S. Xu, Z. Jiang, J. Xu, Q. Liu, and X. Cao. 2014. The STAT3-binding long noncoding RNA lnc-DC controls human dendritic cell differentiation. Science 344: 310-313.
-
(2014)
Science
, vol.344
, pp. 310-313
-
-
Wang, P.1
Xue, Y.2
Han, Y.3
Lin, L.4
Wu, C.5
Xu, S.6
Jiang, Z.7
Xu, J.8
Liu, Q.9
Cao, X.10
-
40
-
-
84857193362
-
The composition and signaling of the IL-35 receptor are unconventional
-
Collison, L. W., G. M. Delgoffe, C. S. Guy, K. M. Vignali, V. Chaturvedi, D. Fairweather, A. R. Satoskar, K. C. Garcia, C. A. Hunter, C. G. Drake, et al. 2012. The composition and signaling of the IL-35 receptor are unconventional. Nat. Immunol. 13: 290-299.
-
(2012)
Nat. Immunol
, vol.13
, pp. 290-299
-
-
Collison, L.W.1
Delgoffe, G.M.2
Guy, C.S.3
Vignali, K.M.4
Chaturvedi, V.5
Fairweather, D.6
Satoskar, A.R.7
Garcia, K.C.8
Hunter, C.A.9
Drake, C.G.10
-
41
-
-
84859968982
-
Critical role of STAT5 transcription factor tetramerization for cytokine responses and normal immune function
-
Lin, J.-X., P. Li, D. Liu, H.-T. Jin, J. He, M. Ata Ur Rasheed, Y. Rochman, L. Wang, K. Cui, C. Liu, et al. 2012. Critical role of STAT5 transcription factor tetramerization for cytokine responses and normal immune function. Immunity 36: 586-599.
-
(2012)
Immunity
, vol.36
, pp. 586-599
-
-
Lin, J.-X.1
Li, P.2
Liu, D.3
Jin, H.-T.4
He, J.5
Rochman, Y.6
Wang, L.7
Cui, K.8
Liu, C.9
-
42
-
-
84892782565
-
STAT1-cooperative DNA binding distinguishes type 1 from type 2 interferon signaling
-
Begitt, A., M. Droescher, T. Meyer, C. D. Schmid, M. Baker, F. Antunes, K.-P. Knobeloch, M. R. Owen, R. Naumann, T. Decker, and U. Vinkemeier. 2014. STAT1-cooperative DNA binding distinguishes type 1 from type 2 interferon signaling. Nat. Immunol. 15: 168-176.
-
(2014)
Nat. Immunol
, vol.15
, pp. 168-176
-
-
Begitt, A.1
Droescher, M.2
Meyer, T.3
Schmid, C.D.4
Baker, M.5
Antunes, F.6
Knobeloch, K.-P.7
Owen, M.R.8
Naumann, R.9
Decker, T.10
Vinkemeier, U.11
-
43
-
-
34948870247
-
High basal STAT4 balanced by STAT1 induction to control type 1 interferon effects in natural killer cells
-
Miyagi, T., M. P. Gil, X. Wang, J. Louten, W. M. Chu, and C. A. Biron. 2007. High basal STAT4 balanced by STAT1 induction to control type 1 interferon effects in natural killer cells. J. Exp. Med. 204: 2383-2396.
-
(2007)
J. Exp. Med
, vol.204
, pp. 2383-2396
-
-
Miyagi, T.1
Gil, M.P.2
Wang, X.3
Louten, J.4
Chu, W.M.5
Biron, C.A.6
-
44
-
-
0034605042
-
Essential role of signal transducer and activator of transcription (Stat)5a but not Stat5b for Flt3-dependent signaling
-
Zhang, S., S. Fukuda, Y. Lee, G. Hangoc, S. Cooper, R. Spolski, W. J. Leonard, and H. E. Broxmeyer. 2000. Essential role of signal transducer and activator of transcription (Stat)5a but not Stat5b for Flt3-dependent signaling. J. Exp. Med. 192: 719-728.
-
(2000)
J. Exp. Med
, vol.192
, pp. 719-728
-
-
Zhang, S.1
Fukuda, S.2
Lee, Y.3
Hangoc, G.4
Cooper, S.5
Spolski, R.6
Leonard, W.J.7
Broxmeyer, H.E.8
-
45
-
-
84862776933
-
Pyruvate kinase M2 regulates gene transcription by acting as a protein kinase
-
Gao, X., H. Wang, J. J. Yang, X. Liu, and Z.-R. Liu. 2012. Pyruvate kinase M2 regulates gene transcription by acting as a protein kinase. Mol. Cell 45: 598-609.
-
(2012)
Mol. Cell
, vol.45
, pp. 598-609
-
-
Gao, X.1
Wang, H.2
Yang, J.J.3
Liu, X.4
Liu, Z.-R.5
-
46
-
-
80054694130
-
Activation of STAT6 by STING is critical for antiviral innate immunity
-
Chen, H., H. Sun, F. You, W. Sun, X. Zhou, L. Chen, J. Yang, Y. Wang, H. Tang, Y. Guan, et al. 2011. Activation of STAT6 by STING is critical for antiviral innate immunity. Cell 147: 436-446.
-
(2011)
Cell
, vol.147
, pp. 436-446
-
-
Chen, H.1
Sun, H.2
You, F.3
Sun, W.4
Zhou, X.5
Chen, L.6
Yang, J.7
Wang, Y.8
Tang, H.9
Guan, Y.10
-
47
-
-
84874282698
-
CDK8 kinase phosphorylates transcription factor STAT1 to selectively regulate the interferon response
-
Bancerek, J., Z. C. Poss, I. Steinparzer, V. Sedlyarov, T. Pfaffenwimmer, I. Mikulic, L. Dölken, B. Strobl, M. Muller, D. J. Taatjes, and P. Kovarik. 2013. CDK8 kinase phosphorylates transcription factor STAT1 to selectively regulate the interferon response. Immunity 38: 250-262.
-
(2013)
Immunity
, vol.38
, pp. 250-262
-
-
Bancerek, J.1
Poss, Z.C.2
Steinparzer, I.3
Sedlyarov, V.4
Pfaffenwimmer, T.5
Mikulic, I.6
Dölken, L.7
Strobl, B.8
Muller, M.9
Taatjes, D.J.10
Kovarik, P.11
-
48
-
-
0034658024
-
Serine phosphorylation of STATs
-
Decker, T., and P. Kovarik. 2000. Serine phosphorylation of STATs. Oncogene 19: 2628-2637.
-
(2000)
Oncogene
, vol.19
, pp. 2628-2637
-
-
Decker, T.1
Kovarik, P.2
-
49
-
-
0037125988
-
STAT4 serine phosphorylation is critical for IL-12-induced IFN-gamma production but not for cell proliferation
-
Morinobu, A., M. Gadina, W. Strober, R. Visconti, A. Fornace, C. Montagna, G. M. Feldman, R. Nishikomori, and J. J. O'Shea. 2002. STAT4 serine phosphorylation is critical for IL-12-induced IFN-gamma production but not for cell proliferation. Proc. Natl. Acad. Sci. USA 99: 12281-12286.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 12281-12286
-
-
Morinobu, A.1
Gadina, M.2
Strober, W.3
Visconti, R.4
Fornace, A.5
Montagna, C.6
Feldman, G.M.7
Nishikomori, R.8
O'Shea, J.J.9
-
50
-
-
0347624595
-
Essential role of STAT3 in postnatal survival and growth revealed by mice lacking STAT3 serine 727 phosphorylation
-
Shen, Y., K. Schlessinger, X. Zhu, E. Meffre, F. Quimby, D. E. Levy, and J. E. Darnell, Jr. 2004. Essential role of STAT3 in postnatal survival and growth revealed by mice lacking STAT3 serine 727 phosphorylation. Mol. Cell. Biol. 24: 407-419.
-
(2004)
Mol. Cell. Biol
, vol.24
, pp. 407-419
-
-
Shen, Y.1
Schlessinger, K.2
Zhu, X.3
Meffre, E.4
Quimby, F.5
Levy, D.E.6
Darnell, J.E.7
-
51
-
-
0346792731
-
Phosphorylation of the Stat1 transactivation domain is required for full-fledged IFN-gamma-dependent innate immunity
-
Varinou, L., K. Ramsauer, M. Karaghiosoff, T. Kolbe, K. Pfeffer, M. Muller, and T. Decker. 2003. Phosphorylation of the Stat1 transactivation domain is required for full-fledged IFN-gamma-dependent innate immunity. Immunity 19: 793-802.
-
(2003)
Immunity
, vol.19
, pp. 793-802
-
-
Varinou, L.1
Ramsauer, K.2
Karaghiosoff, M.3
Kolbe, T.4
Pfeffer, K.5
Muller, M.6
Decker, T.7
-
52
-
-
77956589191
-
Stat5a serine 725 and 779 phosphorylation is a prerequisite for hematopoietic transformation
-
Friedbichler, K., M. A. Kerenyi, B. Kovacic, G. Li, A. Hoelbl, S. Yahiaoui, V. Sexl, E. W. Mullner, S. Fajmann, S. Cerny-Reiterer, et al. 2010. Stat5a serine 725 and 779 phosphorylation is a prerequisite for hematopoietic transformation. Blood 116: 1548-1558.
-
(2010)
Blood
, vol.116
, pp. 1548-1558
-
-
Friedbichler, K.1
Kerenyi, M.A.2
Kovacic, B.3
Li, G.4
Hoelbl, A.5
Yahiaoui, S.6
Sexl, V.7
Mullner, E.W.8
Fajmann, S.9
-
53
-
-
8844266055
-
Arginine methylation of STAT1: A reassessment
-
587-589, discussion
-
Meissner, T., E. Krause, I. Lödige, and U. Vinkemeier. 2004. Arginine methylation of STAT1: A reassessment. Cell 119: 587-589, discussion 589-590.
-
(2004)
Cell
, vol.119
, pp. 589-590
-
-
Meissner, T.1
Krause, E.2
Lödige, I.3
Vinkemeier, U.4
-
54
-
-
13744255376
-
Cell signaling. Stat acetylation-A key facet of cytokine signaling?
-
O'Shea, J. J., Y. Kanno, X. Chen, and D. E. Levy. 2005. Cell signaling. Stat acetylation-A key facet of cytokine signaling? Science 307: 217-218.
-
(2005)
Science
, vol.307
, pp. 217-218
-
-
O'Shea, J.J.1
Kanno, Y.2
Chen, X.3
Levy, D.E.4
-
55
-
-
84879000598
-
Phosphorylation of EZH2 activates STAT3 signaling via STAT3 methylation and promotes tumorigenicity of glioblastoma stemlike cells
-
Kim, E., M. Kim, D.-H. Woo, Y. Shin, J. Shin, N. Chang, Y. T. Oh, H. Kim, J. Rheey, I. Nakano, et al. 2013. Phosphorylation of EZH2 activates STAT3 signaling via STAT3 methylation and promotes tumorigenicity of glioblastoma stemlike cells. Cancer Cell 23: 839-852.
-
(2013)
Cancer Cell
, vol.23
, pp. 839-852
-
-
Kim, E.1
Kim, M.2
Woo, D.-H.3
Shin, Y.4
Shin, J.5
Chang, N.6
Oh, Y.T.7
Kim, H.8
Rheey, J.9
Nakano, I.10
-
56
-
-
78650717706
-
Reversible methylation of promoter-bound STAT3 by histone-modifying enzymes
-
Yang, J., J. Huang, M. Dasgupta, N. Sears, M. Miyagi, B. Wang, M. R. Chance, X. Chen, Y. Du, Y. Wang, et al. 2010. Reversible methylation of promoter-bound STAT3 by histone-modifying enzymes. Proc. Natl. Acad. Sci. USA 107: 21499-21504.
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 21499-21504
-
-
Yang, J.1
Huang, J.2
Dasgupta, M.3
Sears, N.4
Miyagi, M.5
Wang, B.6
Chance, M.R.7
Chen, X.8
Du, Y.9
Wang, Y.10
-
57
-
-
79961003506
-
SUMO conjugation of STAT1 protects cells from hyperresponsiveness to IFNg
-
Begitt, A., M. Droescher, K. P. Knobeloch, and U. Vinkemeier. 2011. SUMO conjugation of STAT1 protects cells from hyperresponsiveness to IFNg. Blood 118: 1002-1007.
-
(2011)
Blood
, vol.118
, pp. 1002-1007
-
-
Begitt, A.1
Droescher, M.2
Knobeloch, K.P.3
Vinkemeier, U.4
-
58
-
-
84863393395
-
SUMO-specific protease 1 is critical for early lymphoid development through regulation of STAT5 activation
-
Van Nguyen, T., P. Angkasekwinai, H. Dou, F.-M. Lin, L.-S. Lu, J. Cheng, Y. E. Chin, C. Dong, and E. T. Yeh. 2012. SUMO-specific protease 1 is critical for early lymphoid development through regulation of STAT5 activation. Mol. Cell 45: 210-221.
-
(2012)
Mol. Cell
, vol.45
, pp. 210-221
-
-
Van Nguyen, T.1
Angkasekwinai, P.2
Dou, H.3
Lin, F.-M.4
Lu, L.-S.5
Cheng, J.6
Chin, Y.E.7
Dong, C.8
Yeh, E.T.9
-
59
-
-
84896490633
-
Toward a new STATe: The role of STATs in mitochondrial function
-
Meier, J. A., and A. C. Larner. 2014. Toward a new STATe: The role of STATs in mitochondrial function. Semin. Immunol. 26: 20-28.
-
(2014)
Semin. Immunol
, vol.26
, pp. 20-28
-
-
Meier, J.A.1
Larner, A.C.2
-
60
-
-
70349975711
-
JAK2 phosphorylates histone H3Y41 and excludes HP1alpha from chromatin
-
Dawson, M. A., A. J. Bannister, B. Göttgens, S. D. Foster, T. Bartke, A. R. Green, and T. Kouzarides. 2009. JAK2 phosphorylates histone H3Y41 and excludes HP1alpha from chromatin. Nature 461: 819-822.
-
(2009)
Nature
, vol.461
, pp. 819-822
-
-
Dawson, M.A.1
Bannister, A.J.2
Göttgens, B.3
Foster, S.D.4
Bartke, T.5
Green, A.R.6
Kouzarides, T.7
-
61
-
-
84872065897
-
JAKs and STATs in immunity, immunodeficiency, and cancer
-
O'Shea, J. J., S. M. Holland, and L. M. Staudt. 2013. JAKs and STATs in immunity, immunodeficiency, and cancer. N. Engl. J. Med. 368: 161-170.
-
(2013)
N. Engl. J. Med
, vol.368
, pp. 161-170
-
-
O'Shea, J.J.1
Holland, S.M.2
Staudt, L.M.3
-
63
-
-
0027403374
-
Interleukin-2 receptor gamma chain mutation results in X-linked severe combined immunodeficiency in humans
-
Noguchi, M., H. Yi, H. M. Rosenblatt, A. H. Filipovich, S. Adelstein, W. S. Modi, O. W. McBride, and W. J. Leonard. 1993. Interleukin-2 receptor gamma chain mutation results in X-linked severe combined immunodeficiency in humans. Cell 73: 147-157.
-
(1993)
Cell
, vol.73
, pp. 147-157
-
-
Noguchi, M.1
Yi, H.2
Rosenblatt, H.M.3
Filipovich, A.H.4
Adelstein, S.5
Modi, W.S.6
McBride, O.W.7
Leonard, W.J.8
-
64
-
-
0029164841
-
Mutations of Jak-3 gene in patients with autosomal severe combined immune deficiency (SCID
-
Macchi, P., A. Villa, S. Giliani, M. G. Sacco, A. Frattini, F. Porta, A. G. Ugazio, J. A. Johnston, F. Candotti, J. J. O'Shea, et al. 1995. Mutations of Jak-3 gene in patients with autosomal severe combined immune deficiency (SCID). Nature 377: 65-68.
-
(1995)
Nature
, vol.377
, pp. 65-68
-
-
Macchi, P.1
Villa, A.2
Giliani, S.3
Sacco, M.G.4
Frattini, A.5
Porta, F.6
Ugazio, A.G.7
Johnston, J.A.8
Candotti, F.9
O'Shea, J.J.10
-
65
-
-
0028857954
-
Mutation of Jak3 in a patient with SCID: Essential role of Jak3 in lymphoid development
-
Russell, S. M., N. Tayebi, H. Nakajima, M. C. Riedy, J. L. Roberts, M. J. Aman, T.-S. Migone, M. Noguchi, M. L. Markert, R. H. Buckley, et al. 1995. Mutation of Jak3 in a patient with SCID: Essential role of Jak3 in lymphoid development. Science 270: 797-800.
-
(1995)
Science
, vol.270
, pp. 797-800
-
-
Russell, S.M.1
Tayebi, N.2
Nakajima, H.3
Riedy, M.C.4
Roberts, J.L.5
Aman, M.J.6
Migone, T.-S.7
Noguchi, M.8
Markert, M.L.9
Buckley, R.H.10
-
66
-
-
84900428801
-
A mouse model of HIES reveals pro- and anti-inflammatory functions of STAT3
-
Steward-Tharp, S. M., A. Laurence, Y. Kanno, A. Kotlyar, A. V. Villarino, G. Sciume, S. Kuchen, W. Resch, E. A. Wohlfert, K. Jiang, et al. 2014. A mouse model of HIES reveals pro- and anti-inflammatory functions of STAT3. Blood 123: 2978-2987.
-
(2014)
Blood
, vol.123
, pp. 2978-2987
-
-
Steward-Tharp, S.M.1
Laurence, A.2
Kanno, Y.3
Kotlyar, A.4
Villarino, A.V.5
Sciume, G.6
Kuchen, S.7
Resch, W.8
Wohlfert, E.A.9
Jiang, K.10
-
67
-
-
84905576130
-
Activating germline mutations in STAT3 cause early-onset multi-organ autoimmune disease
-
Flanagan, S. E., E. Haapaniemi, M. A. Russell, R. Caswell, H. Lango Allen, E. De Franco, T. J. McDonald, H. Rajala, A. Ramelius, J. Barton, et al. 2014. Activating germline mutations in STAT3 cause early-onset multi-organ autoimmune disease. Nat. Genet. 46: 812-814.
-
(2014)
Nat. Genet
, vol.46
, pp. 812-814
-
-
Flanagan, S.E.1
Haapaniemi, E.2
Russell, M.A.3
Caswell, R.4
Lango Allen, H.5
De Franco, E.6
McDonald, T.J.7
Rajala, H.8
Ramelius, A.9
Barton, J.10
-
68
-
-
84880920122
-
Bringing genome-wide association findings into clinical use
-
Manolio, T. A. 2013. Bringing genome-wide association findings into clinical use. Nat. Rev. Genet. 14: 549-558.
-
(2013)
Nat. Rev. Genet
, vol.14
, pp. 549-558
-
-
Manolio, T.A.1
-
69
-
-
40049100646
-
Discovering susceptibility genes for asthma and allergy
-
Vercelli, D. 2008. Discovering susceptibility genes for asthma and allergy. Nat. Rev. Immunol. 8: 169-182.
-
(2008)
Nat. Rev. Immunol
, vol.8
, pp. 169-182
-
-
Vercelli, D.1
-
70
-
-
0036251154
-
Stat proteins and oncogenesis
-
Bromberg, J. 2002. Stat proteins and oncogenesis. J. Clin. Invest. 109: 1139-1142.
-
(2002)
J. Clin. Invest
, vol.109
, pp. 1139-1142
-
-
Bromberg, J.1
-
71
-
-
70350500225
-
STATs in cancer inflammation and immunity: A leading role for STAT3
-
Yu, H., D. Pardoll, and R. Jove. 2009. STATs in cancer inflammation and immunity: A leading role for STAT3. Nat. Rev. Cancer 9: 798-809.
-
(2009)
Nat. Rev. Cancer
, vol.9
, pp. 798-809
-
-
Yu, H.1
Pardoll, D.2
Jove, R.3
-
72
-
-
34548240698
-
Role of JAK2 in the pathogenesis and therapy of myeloproliferative disorders
-
Levine, R. L., A. Pardanani, A. Tefferi, and D. G. Gilliland. 2007. Role of JAK2 in the pathogenesis and therapy of myeloproliferative disorders. Nat. Rev. Cancer 7: 673-683.
-
(2007)
Nat. Rev. Cancer
, vol.7
, pp. 673-683
-
-
Levine, R.L.1
Pardanani, A.2
Tefferi, A.3
Gilliland, D.G.4
-
73
-
-
80052492285
-
The pseudokinase domain of JAK2 is a dual-specificity protein kinase that negatively regulates cytokine signaling
-
Ungureanu, D., J. Wu, T. Pekkala, Y. Niranjan, C. Young, O. N. Jensen, C.-F. Xu, T. A. Neubert, R. C. Skoda, S. R. Hubbard, and O. Silvennoinen. 2011. The pseudokinase domain of JAK2 is a dual-specificity protein kinase that negatively regulates cytokine signaling. Nat. Struct. Mol. Biol. 18: 971-976.
-
(2011)
Nat. Struct. Mol. Biol
, vol.18
, pp. 971-976
-
-
Ungureanu, D.1
Wu, J.2
Pekkala, T.3
Niranjan, Y.4
Young, C.5
Jensen, O.N.6
Xu, C.-F.7
Neubert, T.A.8
Skoda, R.C.9
Hubbard, S.R.10
Silvennoinen, O.11
-
74
-
-
62849094732
-
Selectivity and therapeutic inhibition of kinases: To be or not to be?
-
Ghoreschi, K., A. Laurence, and J. J. O'Shea. 2009. Selectivity and therapeutic inhibition of kinases: To be or not to be? Nat. Immunol. 10: 356-360.
-
(2009)
Nat. Immunol
, vol.10
, pp. 356-360
-
-
Ghoreschi, K.1
Laurence, A.2
O'Shea, J.J.3
-
75
-
-
84888048954
-
A blinded, randomized, placebocontrolled trial of the efficacy and safety of the Janus kinase inhibitor oclacitinib (Apoquel) in client-owned dogs with atopic dermatitis
-
Cosgrove, S. B., J. A.Wren, D. M. Cleaver, K. F.Walsh, S. I. Follis, V. I. King, J.-K. S. Tena, and M. R. Stegemann. 2013. A blinded, randomized, placebocontrolled trial of the efficacy and safety of the Janus kinase inhibitor oclacitinib (Apoquel) in client-owned dogs with atopic dermatitis. Vet. Dermatol. 24: 587- 597, e141-e142.
-
(2013)
Vet. Dermatol
, vol.24
, Issue.587-597
, pp. e141-e142
-
-
Cosgrove, S.B.1
Cleaver, D.M.2
Follis, S.I.3
King, V.I.4
Tena, J.-K.5
Stegemann, M.R.6
-
76
-
-
84893969810
-
Nucleic acid-based approaches to STAT inhibition
-
Sen, M., and J. R. Grandis. 2012. Nucleic acid-based approaches to STAT inhibition. JAK-STAT 1: 285-291.
-
(2012)
JAK-STAT
, vol.1
, pp. 285-291
-
-
Sen, M.1
Grandis, J.R.2
-
77
-
-
84899652032
-
Selective inhibition of the function of tyrosine-phosphorylated STAT3 with a phosphorylation site-specific intrabody
-
Koo, M. Y., J. Park, J. M. Lim, S. Y. Joo, S.-P. Shin, H. B. Shim, J. Chung, D. Kang, H. A. Woo, and S. G. Rhee. 2014. Selective inhibition of the function of tyrosine-phosphorylated STAT3 with a phosphorylation site-specific intrabody. Proc. Natl. Acad. Sci. USA 111: 6269-6274.
-
(2014)
Proc. Natl. Acad. Sci. USA
, vol.111
, pp. 6269-6274
-
-
Koo, M.Y.1
Park, J.2
Lim, J.M.3
Joo, S.Y.4
Shin, S.-P.5
Shim, H.B.6
Chung, J.7
Kang, D.8
Woo, H.A.9
Rhee, S.G.10
-
78
-
-
84921494433
-
Autoimmunity, hypogammaglobulinemia, lymphoproliferation and mycobacterial disease in patients with dominant activating mutations in STAT3
-
Haapaniemi, E. M., M. Kaustio, H. L. M. Rajala, A. J. van Adrichem, L. Kainulainen, V. Glumoff, R. Doffinger, H. Kuusanmaki, T. Heiskanen-Kosma, L. Trotta, et al. 2014. Autoimmunity, hypogammaglobulinemia, lymphoproliferation and mycobacterial disease in patients with dominant activating mutations in STAT3. Blood. DOI: 10.1182/blood-2014-04-570101.
-
(2014)
Blood
-
-
Haapaniemi, E.M.1
Kaustio, M.2
Rajala, H.L.M.3
Van Adrichem, A.J.4
Kainulainen, L.5
Glumoff, V.6
Doffinger, R.7
Kuusanmaki, H.8
Trotta, L.9
-
79
-
-
84921525891
-
Early-onset lymphoproliferation and autoimmunity caused by germline STAT3 gain-offunction mutations
-
Milner, J. D., T. P. Vogel, L. Forbes, C. A. Ma, A. Stray-Pedersen, J. E. Niemela, J. J. Lyons, K. R. Engelhardt, Y. Zhang, N. Topcagic, et al. 2014. Early-onset lymphoproliferation and autoimmunity caused by germline STAT3 gain-offunction mutations. Blood. DOI: 10.1182/blood-2014-09-602763.
-
(2014)
Blood
-
-
Milner, J.D.1
Vogel, T.P.2
Forbes, L.3
Ma, C.A.4
Niemela, J.E.5
Lyons, J.J.6
Engelhardt, K.R.7
Zhang, Y.8
Topcagic, N.9
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