-
1
-
-
0141483083
-
Screening for mammalian neural genes via fluorescence-activated cell sorter purification of neural precursors from Sox1-gfp knock-in mice
-
Aubert J, MP Stavridis, S Tweedie, M O'Reilly, K Vierlinger, M Li, P Ghazal, T Pratt, JO Mason, D Roy and A Smith. (2003). Screening for mammalian neural genes via fluorescence-activated cell sorter purification of neural precursors from Sox1-gfp knock-in mice. Proc Natl Acad Sci U S A 100 (Suppl. 1):11836-11841.
-
(2003)
Proc Natl Acad Sci U S A.
, vol.100
, Issue.SUPPL.1
, pp. 11836-11841
-
-
Aubert, J.1
Stavridis, M.P.2
Tweedie, S.3
O'Reilly, M.4
Vierlinger, K.5
Li, M.6
Ghazal, P.7
Pratt, T.8
Mason, J.O.9
Roy, D.10
Smith, A.11
-
2
-
-
0033517123
-
STAT3 activation is sufficient to maintain an undifferentiated state of mouse embryonic stem cells
-
Matsuda T, T Nakamura, K Nakao, T Arai, M Katsuki, T Heike and T Yokota. (1999). STAT3 activation is sufficient to maintain an undifferentiated state of mouse embryonic stem cells. Embo J 18:4261-4269.
-
(1999)
Embo J
, vol.18
, pp. 4261-4269
-
-
Matsuda, T.1
Nakamura, T.2
Nakao, K.3
Arai, T.4
Katsuki, M.5
Heike, T.6
Yokota, T.7
-
3
-
-
0036238817
-
The Raf/MEK/ERK signal transduction cascade as a target for chemotherapeutic intervention in leukemia
-
Lee JT, Jr. and JA McCubrey. (2002). The Raf/MEK/ERK signal transduction cascade as a target for chemotherapeutic intervention in leukemia. Leukemia 16:486-507.
-
(2002)
Leukemia
, vol.16
, pp. 486-507
-
-
Lee Jr., J.T.1
McCubrey, J.A.2
-
4
-
-
0032512740
-
Fibroblast variants nonresponsive to fibroblast growth factor 1 are defective in its nuclear translocation
-
Mehta VB, L Connors, HC Wang and IM Chiu. (1998). Fibroblast variants nonresponsive to fibroblast growth factor 1 are defective in its nuclear translocation. J Biol Chem 273:4197-4205.
-
(1998)
J Biol Chem
, vol.273
, pp. 4197-4205
-
-
Mehta, V.B.1
Connors, L.2
Wang, H.C.3
Chiu, I.M.4
-
5
-
-
67650032868
-
A parallel circuit of LIF signalling pathways maintains pluripotency of mouse ES cells
-
Niwa H, K Ogawa, D Shimosato and K Adachi. (2009). A parallel circuit of LIF signalling pathways maintains pluripotency of mouse ES cells. Nature 460:118-122.
-
(2009)
Nature
, vol.460
, pp. 118-122
-
-
Niwa, H.1
Ogawa, K.2
Shimosato, D.3
Adachi, K.4
-
6
-
-
33749633094
-
The Grb2/Mek pathway represses Nanog in murine embryonic stem cells
-
Hamazaki T, SM Kehoe, T Nakano and N Terada. (2006). The Grb2/Mek pathway represses Nanog in murine embryonic stem cells. Mol Cell Biol 26:7539-7549.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 7539-7549
-
-
Hamazaki, T.1
Kehoe, S.M.2
Nakano, T.3
Terada, N.4
-
7
-
-
0032559228
-
Sprouty encodes a novel antagonist of FGF signaling that patterns apical branching of the Drosophila airways
-
Hacohen N, S Kramer, D Sutherland, Y Hiromi and MA Krasnow. (1998). Sprouty encodes a novel antagonist of FGF signaling that patterns apical branching of the Drosophila airways. Cell 92:253-263.
-
(1998)
Cell
, vol.92
, pp. 253-263
-
-
Hacohen, N.1
Kramer, S.2
Sutherland, D.3
Hiromi, Y.4
Krasnow, M.A.5
-
8
-
-
0035809919
-
Mammalian sprouty-1 and - 2 are membrane-anchored phosphoprotein inhibitors of growth factor signaling in endothelial cells
-
Impagnatiello MA, S Weitzer, G Gannon, A Compagni, M Cotten and G Christofori. (2001). Mammalian sprouty-1 and - 2 are membrane-anchored phosphoprotein inhibitors of growth factor signaling in endothelial cells. J Cell Biol 152: 1087-1098.
-
(2001)
J Cell Biol
, vol.152
, pp. 1087-1098
-
-
Impagnatiello, M.A.1
Weitzer, S.2
Gannon, G.3
Compagni, A.4
Cotten, M.5
Christofori, G.6
-
9
-
-
0036479310
-
Sprouty2 inhibits the Ras/MAP kinase pathway by inhibiting the activation of Raf
-
Yusoff P, DH Lao, SH Ong, ES Wong, J Lim, TL Lo, HF Leong, CW Fong and GR Guy. (2002). Sprouty2 inhibits the Ras/MAP kinase pathway by inhibiting the activation of Raf. J Biol Chem 277:3195-3201.
-
(2002)
J Biol Chem
, vol.277
, pp. 3195-3201
-
-
Yusoff, P.1
Lao, D.H.2
Ong, S.H.3
Wong, E.S.4
Lim, J.5
Lo, T.L.6
Leong, H.F.7
Fong, C.W.8
Guy, G.R.9
-
10
-
-
30644457873
-
Efficient suppression of FGF-2-induced ERK activation by the cooperative interaction among mammalian Sprouty isoforms
-
Ozaki K, S Miyazaki, S Tanimura and M Kohno. (2005). Efficient suppression of FGF-2-induced ERK activation by the cooperative interaction among mammalian Sprouty isoforms. J Cell Sci 118:5861-5871.
-
(2005)
J Cell Sci
, vol.118
, pp. 5861-5871
-
-
Ozaki, K.1
Miyazaki, S.2
Tanimura, S.3
Kohno, M.4
-
11
-
-
2342483086
-
Promotionand attenuationofFGF signaling through the Ras-MAPK pathway
-
TsangMand IBDawid. (2004).Promotionand attenuationofFGF signaling through the Ras-MAPK pathway. Sci STKE 2004:pe17.
-
(2004)
Sci STKE 2004:pe17
-
-
Tsang, M.1
Dawid, I.B.2
-
12
-
-
0030875352
-
Leukemia inhibitory factor-dependent transcriptional activation in embryonic stem cells
-
Boeuf H, C Hauss, FD Graeve, N Baran and C Kedinger. (1997). Leukemia inhibitory factor-dependent transcriptional activation in embryonic stem cells. J Cell Biol 138:1207-1217.
-
(1997)
J Cell Biol
, vol.138
, pp. 1207-1217
-
-
Boeuf, H.1
Hauss, C.2
Graeve, F.D.3
Baran, N.4
Kedinger, C.5
-
13
-
-
0032127977
-
Selfrenewal of pluripotent embryonic stem cells is mediated via activation of STAT3
-
Niwa H, T Burdon, I Chambers and A Smith. (1998). Selfrenewal of pluripotent embryonic stem cells is mediated via activation of STAT3. Genes Dev 12:2048-2060.
-
(1998)
Genes Dev
, vol.12
, pp. 2048-2060
-
-
Niwa, H.1
Chambers, T.B.I.2
Smith, A.3
-
14
-
-
0033049657
-
Essential role of STAT3 for embryonic stem cell pluripotency
-
Raz R, CK Lee, LA Cannizzaro, P d'Eustachio and DE Levy. (1999). Essential role of STAT3 for embryonic stem cell pluripotency. Proc Natl Acad Sci U S A 96:2846-2851.
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 2846-2851
-
-
Raz, R.1
Lee, C.K.2
Cannizzaro, L.A.3
D'Eustachio, P.4
Levy, D.E.5
-
15
-
-
0346157324
-
Acquiring signalling specificity from the cytokine receptor gp130
-
ErnstMand BJ Jenkins. (2004). Acquiring signalling specificity from the cytokine receptor gp130. Trends Genet 20:23-32.
-
(2004)
Trends Genet
, vol.20
, pp. 23-32
-
-
Mand, E.1
Jenkins, B.J.2
-
16
-
-
16844364151
-
LIF/STAT3 controls ES cell self-renewal and pluripotency by a Myc-dependent mechanism
-
Cartwright P, C McLean, A Sheppard, D Rivett, K Jones and S Dalton. (2005). LIF/STAT3 controls ES cell self-renewal and pluripotency by a Myc-dependent mechanism. Development 132:885-896.
-
(2005)
Development
, vol.132
, pp. 885-896
-
-
Cartwright, P.1
McLean, C.2
Sheppard, A.3
Rivett, D.4
Jones, K.5
Dalton, S.6
-
17
-
-
38149071784
-
The role of SOCS3 in modulating leukaemia inhibitory factor signalling during murine placental development
-
Boyle K and L Robb. (2008). The role of SOCS3 in modulating leukaemia inhibitory factor signalling during murine placental development. J Reprod Immunol 77:1-6.
-
(2008)
J Reprod Immunol
, vol.77
, pp. 1-6
-
-
Boyle, K.1
Robb, L.2
-
18
-
-
33744990866
-
Absence of suppressor of cytokine signalling 3 reduces self-renewal and promotes differentiation in murine embryonic stem cells
-
Forrai A, K Boyle, AH Hart, L Hartley, S Rakar, TA Willson, KM Simpson, AW Roberts, WS Alexander, AK Voss and L Robb. (2006). Absence of suppressor of cytokine signalling 3 reduces self-renewal and promotes differentiation in murine embryonic stem cells. Stem Cells 24:604-614.
-
(2006)
Stem Cells
, vol.24
, pp. 604-614
-
-
Forrai, A.1
Boyle, K.2
Hart, A.H.3
Hartley, L.4
Rakar, S.5
Willson, T.A.6
Simpson, K.M.7
Roberts, A.W.8
Alexander, W.S.9
Voss, A.K.10
Robb, L.11
-
19
-
-
58249133797
-
Deletion of the SOCS box of suppressor of cytokine signaling 3 (SOCS3) in embryonic stem cells reveals SOCS box-dependent regulation of JAK but not STAT phosphorylation
-
Boyle K, JG Zhang, SE Nicholson, E Trounson, JJ Babon, EJ McManus, NA Nicola and L Robb. (2009). Deletion of the SOCS box of suppressor of cytokine signaling 3 (SOCS3) in embryonic stem cells reveals SOCS box-dependent regulation of JAK but not STAT phosphorylation. Cell Signal 21:394-404.
-
(2009)
Cell Signal
, vol.21
, pp. 394-404
-
-
Boyle, K.1
Zhang, J.G.2
Nicholson, S.E.3
Trounson, E.4
Babon, J.J.5
McManus, E.J.6
Nicola, N.A.7
Robb, L.8
-
20
-
-
44349170450
-
The ground state of embryonic stem cell self-renewal
-
Ying QL, J Wray, J Nichols, L Batlle-Morera, B Doble, J Woodgett, P Cohen and A Smith. (2008). The ground state of embryonic stem cell self-renewal. Nature 453:519-523.
-
(2008)
Nature
, vol.453
, pp. 519-523
-
-
Ying, Q.L.1
Wray, J.2
Nichols, J.3
Batlle-Morera, L.4
Doble, B.5
Woodgett, J.6
Cohen, P.7
Smith, A.8
-
21
-
-
0030890453
-
Amphibian FGF-1 is structurally and functionally similar to but antigenically distinguishable from its mammalian counterpart
-
Patrie K, MJ Botelho, SK Ray, VB Mehta and IM Chiu. (1997). Amphibian FGF-1 is structurally and functionally similar to but antigenically distinguishable from its mammalian counterpart. Growth Factors 14:39-57.
-
(1997)
Growth Factors
, vol.14
, pp. 39-57
-
-
Patrie, K.1
Botelho, M.J.2
Ray, S.K.3
Mehta, V.B.4
Chiu, I.M.5
-
22
-
-
0033587477
-
Sitedirected mutagenesis and molecular modeling identify a crucial amino acid in specifying the heparin affinity of FGF-1
-
Patrie KM, MJ Botelho, K Franklin and IM Chiu. (1999). Sitedirected mutagenesis and molecular modeling identify a crucial amino acid in specifying the heparin affinity of FGF-1. Biochemistry 38:9264-9272.
-
(1999)
Biochemistry
, vol.38
, pp. 9264-9272
-
-
Patrie, K.M.1
Botelho, M.J.2
Franklin, K.3
Chiu, I.M.4
-
23
-
-
0030744123
-
Mapping of Stat3 serine phosphorylation to a single residue (727) and evidence that serine phosphorylation has no influence on DNA binding of Stat1 and Stat3
-
Wen Z and JE Darnell, Jr. (1997). Mapping of Stat3 serine phosphorylation to a single residue (727) and evidence that serine phosphorylation has no influence on DNA binding of Stat1 and Stat3. Nucleic Acids Res 25:2062-2067.
-
(1997)
Nucleic Acids Res
, vol.25
, pp. 2062-2067
-
-
Wen, Z.1
Darnell Jr., J.E.2
-
24
-
-
0028913109
-
ASTAT protein domain that determines DNA sequence recognition suggests a novel DNA-binding domain
-
Horvath CM, Z Wenand JE Darnell, Jr. (1995).ASTAT protein domain that determines DNA sequence recognition suggests a novel DNA-binding domain. Genes Dev 9:984-994.
-
(1995)
Genes Dev
, vol.9
, pp. 984-994
-
-
Horvath, C.M.1
Wenand, Z.2
Darnell Jr., J.E.3
-
25
-
-
0028284762
-
Stat3 and Stat4: Members of the family of signal transducers and activators of transcription
-
Zhong Z, Z Wen and JE Darnell, Jr. (1994). Stat3 and Stat4: Members of the family of signal transducers and activators of transcription. Proc Natl Acad Sci U S A 91:4806-4810.
-
(1994)
Proc Natl Acad Sci U S A
, vol.91
, pp. 4806-4810
-
-
Zhong, Z.1
Wen, Z.2
Darnell Jr., J.E.3
-
26
-
-
39649111114
-
Intracellular signaling pathways regulating pluripotency of embryonic stem cells
-
Okita K and S Yamanaka. (2006). Intracellular signaling pathways regulating pluripotency of embryonic stem cells. Curr Stem Cell Res Ther 1:103-111.
-
(2006)
Curr Stem Cell Res Ther
, vol.1
, pp. 103-111
-
-
Okita, K.1
Yamanaka, S.2
-
27
-
-
37048999580
-
WP1066 disrupts Janus kinase-2 and induces caspase-dependent apoptosis in acute myelogenous leukemia cells
-
Ferrajoli A, S Faderl, Q Van, P Koch, D Harris, Z Liu, I Hazan-Halevy, Y Wang, HM Kantarjian, W Priebe and Z Estrov. (2007). WP1066 disrupts Janus kinase-2 and induces caspase-dependent apoptosis in acute myelogenous leukemia cells. Cancer Res 67:11291-11299.
-
(2007)
Cancer Res
, vol.67
, pp. 11291-11299
-
-
Ferrajoli, A.1
Faderl, S.2
Koch P Q.Van3
Harris, D.4
Liu, Z.5
Hazan-Halevy, I.6
Wang, Y.7
Kantarjian, H.M.8
Priebe, W.9
Estrov, Z.10
-
28
-
-
38949086558
-
WP1066, a novel JAK2 inhibitor, suppresses proliferation and induces apoptosis in erythroid human cells carrying the JAK2 V617F mutation
-
Verstovsek S, T Manshouri, A Quintas-Cardama, D Harris, J Cortes, FJ Giles, H Kantarjian,WPriebe and Z Estrov. (2008). WP1066, a novel JAK2 inhibitor, suppresses proliferation and induces apoptosis in erythroid human cells carrying the JAK2 V617F mutation. Clin Cancer Res 14:788-796.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 788-796
-
-
Verstovsek, S.1
Manshouri, T.2
Quintas-Cardama, A.3
Harris, D.4
Cortes, J.5
Giles, F.J.6
Kantarjianwpriebe, H.7
Estrov, Z.8
-
29
-
-
79960772295
-
Tocotrienols: Inflammation and cancer
-
Nesaretnam K and P Meganathan. (2011). Tocotrienols: Inflammation and cancer. Ann N Y Acad Sci 1229:18-22.
-
(2011)
Ann N y Acad Sci
, vol.1229
, pp. 18-22
-
-
Nesaretnam, K.1
Meganathan, P.2
-
30
-
-
77958468408
-
Gamma-Tocotrienol but not gamma-tocopherol blocks STAT3 cell signaling pathway through induction of protein-tyrosine phosphatase SHP-1 and sensitizes tumor cells to chemotherapeutic agents
-
Kannappan R, VR Yadav and BB Aggarwal. (2010). gamma-Tocotrienol but not gamma-tocopherol blocks STAT3 cell signaling pathway through induction of protein-tyrosine phosphatase SHP-1 and sensitizes tumor cells to chemotherapeutic agents. J Biol Chem 285:33520-33528.
-
(2010)
J Biol Chem
, vol.285
, pp. 33520-33528
-
-
Kannappan, R.1
Yadav, V.R.2
Aggarwal, B.B.3
-
31
-
-
0036093058
-
Constitutive activity of signal transducer and activator of transcription 3 protein in acute myeloid leukemia blasts is associated with short disease-free survival
-
Benekli M, Z Xia, KA Donohue, LA Ford, LA Pixley, MR Baer, H Baumann and M Wetzler. (2002). Constitutive activity of signal transducer and activator of transcription 3 protein in acute myeloid leukemia blasts is associated with short disease-free survival. Blood 99:252-257.
-
(2002)
Blood
, vol.99
, pp. 252-257
-
-
Benekli, M.1
Xia, Z.2
Donohue, K.A.3
Ford, L.A.4
Pixley, L.A.5
Baer, M.R.6
Baumann, H.7
Wetzler, M.8
-
32
-
-
0033590636
-
Constitutive activation of the 41-/43-kDa mitogen-activated protein kinase signaling pathway in human tumors
-
Hoshino R, Y Chatani, T Yamori, T Tsuruo, H Oka, O Yoshida, Y Shimada, S Ari-i, H Wada, J Fujimoto and M Kohno. (1999). Constitutive activation of the 41-/43-kDa mitogen-activated protein kinase signaling pathway in human tumors. Oncogene 18:813-822.
-
(1999)
Oncogene
, vol.18
, pp. 813-822
-
-
Hoshino, R.1
Chatani, Y.2
Yamori, T.3
Tsuruo, T.4
Oka, H.5
Yoshida, O.6
Shimada, Y.7
Ari, I.S.8
Wada, H.9
Fujimoto, J.10
Kohno, M.11
-
33
-
-
0037264633
-
Targeting RAS signalling pathways in cancer therapy
-
Downward J. (2003). Targeting RAS signalling pathways in cancer therapy. Nat Rev Cancer 3:11-22.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 11-22
-
-
Downward, J.1
-
34
-
-
0037138370
-
Signaling through the JAK/STAT pathway, recent advances and future challenges
-
Kisseleva T, S Bhattacharya, J Braunstein and CW Schindler. (2002). Signaling through the JAK/STAT pathway, recent advances and future challenges. Gene 285:1-24.
-
(2002)
Gene
, vol.285
, pp. 1-24
-
-
Kisseleva, T.1
Bhattacharya, S.2
Braunstein, J.3
Schindler, C.W.4
-
35
-
-
15844402009
-
Cell fate determination regulated by a transcriptional signal network in the developing mouse brain
-
Fukuda S and T Taga. (2005). Cell fate determination regulated by a transcriptional signal network in the developing mouse brain. Anat Sci Int 80:12-18.
-
(2005)
Anat Sci Int
, vol.80
, pp. 12-18
-
-
Fukuda, S.1
Taga, T.2
-
36
-
-
77952995770
-
Induction and regulation of differentiation in neural stem cells on ultrananocrystalline diamond films
-
Chen YC, DC Lee, TY Tsai, CY Hsiao, JW Liu, CY Kao, HK Lin, HC Chen, TJ Palathinkal, et al. (2010). Induction and regulation of differentiation in neural stem cells on ultrananocrystalline diamond films. Biomaterials 31:5575-5587.
-
(2010)
Biomaterials
, vol.31
, pp. 5575-5587
-
-
Chen, Y.C.1
Lee, D.C.2
Tsai, T.Y.3
Hsiao, C.Y.4
Liu, J.W.5
Kao, C.Y.6
Lin, H.K.7
Chen, H.C.8
Palathinkal, T.J.9
-
37
-
-
59649084032
-
Brain-specific 1B promoter of FGF1 gene facilitates the isolation of neural stem/progenitor cells with selfrenewal and multipotent capacities
-
Hsu YC, DC Lee, SL Chen,WCLiao, JW Lin,WTChiu and IM Chiu. (2009). Brain-specific 1B promoter of FGF1 gene facilitates the isolation of neural stem/progenitor cells with selfrenewal and multipotent capacities. Dev Dyn 238:302-314.
-
(2009)
Dev Dyn
, vol.238
, pp. 302-314
-
-
Hsu, Y.C.1
Lee, D.C.2
Chen, S.L.3
Liao, W.C.4
Lin, J.W.5
Chiu, W.T.6
Chiu, I.M.7
-
38
-
-
67349258579
-
Isolation of neural stem/progenitor cells by using EGF/FGF1 and FGF1B promoterdriven green fluorescence from embryonic and adult mouse brains
-
Lee DC, YC Hsu, YF Chung, CY Hsiao, SL Chen, MS Chen, HK Lin and IM Chiu. (2009). Isolation of neural stem/progenitor cells by using EGF/FGF1 and FGF1B promoterdriven green fluorescence from embryonic and adult mouse brains. Mol Cell Neurosci 41:348-363.
-
(2009)
Mol Cell Neurosci
, vol.41
, pp. 348-363
-
-
Lee, D.C.1
Hsu, Y.C.2
Chung, Y.F.3
Hsiao, C.Y.4
Chen, S.L.5
Chen, M.S.6
Lin, H.K.7
Chiu, I.M.8
-
39
-
-
64849115616
-
SH2B1beta enhances fibroblast growth factor 1 (FGF1)-induced neurite outgrowth through MEK-ERK1/2-STAT3-Egr1 pathway
-
Lin WF, CJ Chen, YJ Chang, SL Chen, IM Chiu and L Chen. (2009). SH2B1beta enhances fibroblast growth factor 1 (FGF1)-induced neurite outgrowth through MEK-ERK1/2-STAT3-Egr1 pathway. Cell Signal 21:1060-1072.
-
(2009)
Cell Signal
, vol.21
, pp. 1060-1072
-
-
Lin, W.F.1
Chen, C.J.2
Chang, Y.J.3
Chen, S.L.4
Chiu, I.M.5
Chen, L.6
-
40
-
-
77951563748
-
The signals of FGFs on the neurogenesis of embryonic stem cells
-
Chen CW, CS Liu, IM Chiu, SC Shen, HC Pan, KH Lee, SZ Lin and HL Su. (2010). The signals of FGFs on the neurogenesis of embryonic stem cells. J Biomed Sci 17:33.
-
(2010)
J Biomed Sci
, vol.17
, pp. 33
-
-
Chen, C.W.1
Liu, C.S.2
Chiu, I.M.3
Shen, S.C.4
Pan, H.C.5
Lee, K.H.6
Lin, S.Z.7
Su, H.L.8
|