-
1
-
-
1042288280
-
The intracellular location and function of proteins of neuronal ceroid lipofuscinoses
-
J. Ezaki and E. Kominami, The intracellular location and function of proteins of neuronal ceroid lipofuscinoses, Brain Pathol 14: 77-85 (2004).
-
(2004)
Brain Pathol
, vol.14
, pp. 77-85
-
-
Ezaki, J.1
Kominami, E.2
-
2
-
-
28244435957
-
Cathepsin deficiency as a model for neuronal ceroid lipofuscinoses
-
J. J. Shacka and K. A. Roth, Cathepsin deficiency as a model for neuronal ceroid lipofuscinoses, Am J Pathol 167: 1473-1476 (2005).
-
(2005)
Am J Pathol
, vol.167
, pp. 1473-1476
-
-
Shacka, J.J.1
Roth, K.A.2
-
3
-
-
34548059220
-
Cathepsin D deficiency and NCL/Batten disease: There’s more to death than apoptosis
-
J. J. Shacka and K. A. Roth, Cathepsin D deficiency and NCL/Batten disease: there’s more to death than apoptosis, Autophagy 3: 474-476 (2007).
-
(2007)
Autophagy
, vol.3
, pp. 474-476
-
-
Shacka, J.J.1
Roth, K.A.2
-
4
-
-
77950675049
-
Neuronopathic Gaucher disease in the mouse: Viable combined selective saposin C deficiency and mutant glucocerebrosidase (V394L) mice with glucosylsphingosine and glucosylceramide accumulation and progressive neurological deficits
-
Y. Sun, B. Liou, H. Ran, M. R. Skelton, M. T. Williams, C. V. Vorhees, K. Kitatani, Y. A. Hannun, D. P. Witte, Y. H. Xu and G. A. Grabowski, Neuronopathic Gaucher disease in the mouse: viable combined selective saposin C deficiency and mutant glucocerebrosidase (V394L) mice with glucosylsphingosine and glucosylceramide accumulation and progressive neurological deficits, Hum Mol Genet 19: 1088-1097 (2010).
-
(2010)
Hum Mol Genet
, vol.19
, pp. 1088-1097
-
-
Sun, Y.1
Liou, B.2
Ran, H.3
Skelton, M.R.4
Williams, M.T.5
Vorhees, C.V.6
Kitatani, K.7
Hannun, Y.A.8
Witte, D.P.9
Xu, Y.H.10
Grabowski, G.A.11
-
5
-
-
77955447007
-
Impaired autophagosomes and lysosomes in neuronopathic Gaucher disease
-
Y. Sun and G. A. Grabowski, Impaired autophagosomes and lysosomes in neuronopathic Gaucher disease, Autophagy 6: 648-649 (2010).
-
(2010)
Autophagy
, vol.6
, pp. 648-649
-
-
Sun, Y.1
Grabowski, G.A.2
-
6
-
-
77955373796
-
Autophagosome maturation is impaired in Fabry disease
-
M. Chevrier, N. Brakch, C. Lesueur, D. Genty, Y. Ramdani, S. Moll, M. Djavaheri-Mergny, C. Brasse-Lagnel, A. Laquerriere, F. Barbey and S. Bekri, Autophagosome maturation is impaired in Fabry disease, Autophagy 6: 589-599 (2010).
-
(2010)
Autophagy
, vol.6
, pp. 589-599
-
-
Chevrier, M.1
Brakch, N.2
Lesueur, C.3
Genty, D.4
Ramdani, Y.5
Moll, S.6
Djavaheri-Mergny, M.7
Brasse-Lagnel, C.8
Laquerriere, A.9
Barbey, F.10
Bekri, S.11
-
7
-
-
67849118764
-
Cystinosis of the brain and spinal cord with associated vasculopathy
-
J. R. Berger, D. A. Dillon, B. A. Young, S. J. Goldstein and P. Nelson, Cystinosis of the brain and spinal cord with associated vasculopathy, J Neurol Sci 284: 182-185 (2009).
-
(2009)
J Neurol Sci
, vol.284
, pp. 182-185
-
-
Berger, J.R.1
Dillon, D.A.2
Young, B.A.3
Goldstein, S.J.4
Nelson, P.5
-
8
-
-
36148991943
-
Cell-autonomous death of cerebellar purkinje neurons with autophagy in Niemann-Pick type C disease
-
D. C. Ko, L. Milenkovic, S. M. Beier, H. Manuel, J. Buchanan and M. P. Scott, Cell-autonomous death of cerebellar purkinje neurons with autophagy in Niemann-Pick type C disease, PLoS Genet 1: 81-95 (2005).
-
(2005)
Plos Genet
, vol.1
, pp. 81-95
-
-
Ko, D.C.1
Milenkovic, L.2
Beier, S.M.3
Manuel, H.4
Buchanan, J.5
Scott, M.P.6
-
9
-
-
0026621090
-
A clinical staging classification for type C Niemann-Pick disease
-
J. J. Higgins, M. C. Patterson, J. M. Dambrosia, A. T. Pikus, P. G. Pentchev, S. Sato, R. O. Brady and N. W. Barton, A clinical staging classification for type C Niemann-Pick disease, Neurology 42: 2286-2290 (1992).
-
(1992)
Neurology
, vol.42
, pp. 2286-2290
-
-
Higgins, J.J.1
Patterson, M.C.2
Dambrosia, J.M.3
Pikus, A.T.4
Pentchev, P.G.5
Sato, S.6
Brady, R.O.7
Barton, N.W.8
-
10
-
-
38649117272
-
Enhanced autophagy and mitochondrial aberrations in murine G(M1)-gangliosidosis
-
A. Takamura, K. Higaki, K. Kajimaki, S. Otsuka, H. Ninomiya, J. Matsuda, K. Ohno, Y. Suzuki and E. Nanba, Enhanced autophagy and mitochondrial aberrations in murine G(M1)-gangliosidosis, Biochem Biophys Res Commun 367: 616-622 (2008).
-
(2008)
Biochem Biophys Res Commun
, vol.367
, pp. 616-622
-
-
Takamura, A.1
Higaki, K.2
Kajimaki, K.3
Otsuka, S.4
Ninomiya, H.5
Matsuda, J.6
Ohno, K.7
Suzuki, Y.8
Nanba, E.9
-
11
-
-
33845343984
-
Sphingolipid metabolism diseases
-
T. Kolter and K. Sandhoff, Sphingolipid metabolism diseases, Biochim Biophys Acta 1758: 2057-2079 (2006).
-
(2006)
Biochim Biophys Acta
, vol.1758
, pp. 2057-2079
-
-
Kolter, T.1
Sandhoff, K.2
-
12
-
-
34248353120
-
Systemic inflammation and neurodegeneration in a mouse model of multiple sulfatase deficiency
-
USA
-
C. Settembre, I. Annunziata, C. Spampanato, D. Zarcone, G. Cobellis, E. Nusco, E. Zito, C. Tacchetti, M. P. Cosma and A. Ballabio, Systemic inflammation and neurodegeneration in a mouse model of multiple sulfatase deficiency, Proc Natl Acad Sci USA 104: 4506-4511 (2007).
-
(2007)
Proc Natl Acad Sci
, vol.104
, pp. 4506-4511
-
-
Settembre, C.1
Annunziata, I.2
Spampanato, C.3
Zarcone, D.4
Cobellis, G.5
Nusco, E.6
Zito, E.7
Tacchetti, C.8
Cosma, M.P.9
Ballabio, A.10
-
13
-
-
79952557240
-
Mucopolysaccharidosis type IIIB may predominantly present with an attenuated clinical phenotype
-
M. J. Valstar, H. T. Bruggenwirth, R. Olmer, R. A. Wevers, F. W. Verheijen, B. J. Poorthuis, D. J. Halley and F. A. Wijburg, Mucopolysaccharidosis type IIIB may predominantly present with an attenuated clinical phenotype, J Inherit Metab Dis 33: 759-767 (2010).
-
(2010)
J Inherit Metab Dis
, vol.33
, pp. 759-767
-
-
Valstar, M.J.1
Bruggenwirth, H.T.2
Olmer, R.3
Wevers, R.A.4
Verheijen, F.W.5
Poorthuis, B.J.6
Halley, D.J.7
Wijburg, F.A.8
-
14
-
-
37549066697
-
A block of autophagy in lysosomal storage disorders
-
C. Settembre, A. Fraldi, L. Jahreiss, C. Spampanato, C. Venturi, D. Medina, R. de Pablo, C. Tacchetti, D. C. Rubinsztein and A. Ballabio, A block of autophagy in lysosomal storage disorders, Hum Mol Genet 17: 119-129 (2008).
-
(2008)
Hum Mol Genet
, vol.17
, pp. 119-129
-
-
Settembre, C.1
Fraldi, A.2
Jahreiss, L.3
Spampanato, C.4
Venturi, C.5
Medina, D.6
De Pablo, R.7
Tacchetti, C.8
Rubinsztein, D.C.9
Ballabio, A.10
-
15
-
-
76249099881
-
Abnormal autophagy, ubiquitination, inflammation and apoptosis are dependent upon lysosomal storage and are useful biomarkers of mucopolysaccharidosis VI
-
A. Tessitore, M. Pirozzi and A. Auricchio, Abnormal autophagy, ubiquitination, inflammation and apoptosis are dependent upon lysosomal storage and are useful biomarkers of mucopolysaccharidosis VI, Pathogenetics 2: 4 (2009).
-
(2009)
Pathogenetics
, vol.2
, pp. 4
-
-
Tessitore, A.1
Pirozzi, M.2
Auricchio, A.3
-
16
-
-
0037072286
-
The neurogenetics of mucolipidosis type IV
-
G. Altarescu, M. Sun, D. F. Moore, J. A. Smith, E. A. Wiggs, B. I. Solomon, N. J. Patronas, K. P. Frei, S. Gupta, C. R. Kaneski, O. W. Quarrell, S. A. Slaugenhaupt, E. Goldin and R. Schiffmann, The neurogenetics of mucolipidosis type IV, Neurology 59: 306-313 (2002).
-
(2002)
Neurology
, vol.59
, pp. 306-313
-
-
Altarescu, G.1
Sun, M.2
Moore, D.F.3
Smith, J.A.4
Wiggs, E.A.5
Solomon, B.I.6
Patronas, N.J.7
Frei, K.P.8
Gupta, S.9
Kaneski, C.R.10
Quarrell, O.W.11
Slaugenhaupt, S.A.12
Goldin, E.13
Schiffmann, R.14
-
17
-
-
33846022005
-
Mitochondrial aberrations in mucolipidosis Type IV
-
J. J. Jennings, Jr., J. H. Zhu, Y. Rbaibi, X. Luo, C. T. Chu and K. Kiselyov, Mitochondrial aberrations in mucolipidosis Type IV, J Biol Chem 281: 39041-39050 (2006).
-
(2006)
J Biol Chem
, vol.281
, pp. 39041-39050
-
-
Jennings, J.J.1
Zhu, J.H.2
Rbaibi, Y.3
Luo, X.4
Chu, C.T.5
Kiselyov, K.6
-
18
-
-
49649089300
-
Autophagic dysfunction in mucolipidosis type IV patients
-
S. Vergarajauregui, P. S. Connelly, M. P. Daniels and R. Puertollano, Autophagic dysfunction in mucolipidosis type IV patients, Hum Mol Genet 17: 2723-2737 (2008).
-
(2008)
Hum Mol Genet
, vol.17
, pp. 2723-2737
-
-
Vergarajauregui, S.1
Connelly, P.S.2
Daniels, M.P.3
Puertollano, R.4
-
19
-
-
70350618320
-
Inhibition of autophagosome formation restores mitochondrial function in mucolipidosis II and III skin fibroblasts
-
T. Otomo, K. Higaki, E. Nanba, K. Ozono and N. Sakai, Inhibition of autophagosome formation restores mitochondrial function in mucolipidosis II and III skin fibroblasts, Mol Genet Metab 98: 393-399 (2009).
-
(2009)
Mol Genet Metab
, vol.98
, pp. 393-399
-
-
Otomo, T.1
Higaki, K.2
Nanba, E.3
Ozono, K.4
Sakai, N.5
-
20
-
-
54049156405
-
The type IV mucolipidosis-associated protein TRPML1 is an endolysosomal iron release channel
-
X. P. Dong, X. Cheng, E. Mills, M. Delling, F. Wang, T. Kurz and H. Xu, The type IV mucolipidosis-associated protein TRPML1 is an endolysosomal iron release channel, Nature 455: 992-996 (2008).
-
(2008)
Nature
, vol.455
, pp. 992-996
-
-
Dong, X.P.1
Cheng, X.2
Mills, E.3
Delling, M.4
Wang, F.5
Kurz, T.6
Xu, H.7
-
21
-
-
78049405392
-
Zinc dyshomeostasis is linked with the loss of mucolipidosis IV-associated TRPML1 ion channel
-
J. L. Eichelsdoerfer, J. A. Evans, S. A. Slaugenhaupt and M. P. Cuajungco, Zinc dyshomeostasis is linked with the loss of mucolipidosis IV-associated TRPML1 ion channel, J Biol Chem 285: 34304-34308 (2010).
-
(2010)
J Biol Chem
, vol.285
, pp. 34304-34308
-
-
Eichelsdoerfer, J.L.1
Evans, J.A.2
Slaugenhaupt, S.A.3
Cuajungco, M.P.4
-
22
-
-
33748413905
-
Autophagy and lysosomes in Pompe disease
-
T. Fukuda, A. Roberts, M. Ahearn, K. Zaal, E. Ralston, P. H. Plotz and N. Raben, Autophagy and lysosomes in Pompe disease, Autophagy 2: 318-320 (2006).
-
(2006)
Autophagy
, vol.2
, pp. 318-320
-
-
Fukuda, T.1
Roberts, A.2
Ahearn, M.3
Zaal, K.4
Ralston, E.5
Plotz, P.H.6
Raben, N.7
-
23
-
-
67249094212
-
Neural deficits contribute to respiratory insufficiency in Pompe disease
-
USA
-
L. R. DeRuisseau, D. D. Fuller, K. Qiu, K. C. DeRuisseau, W. H. Donnelly, Jr., C. Mah, P. J. Reier and B. J. Byrne, Neural deficits contribute to respiratory insufficiency in Pompe disease, Proc Natl Acad Sci USA 106: 9419-9424 (2009).
-
(2009)
Proc Natl Acad Sci
, vol.106
, pp. 9419-9424
-
-
Deruisseau, L.R.1
Fuller, D.D.2
Qiu, K.3
Deruisseau, K.C.4
Donnelly, W.H.5
Mah, C.6
Reier, P.J.7
Byrne, B.J.8
-
24
-
-
43949112966
-
LAMP-2: A control step for phagosome and autophagosome maturation
-
P. Saftig, W. Beertsen and E. L. Eskelinen, LAMP-2: a control step for phagosome and autophagosome maturation, Autophagy 4: 510-512 (2008).
-
(2008)
Autophagy
, vol.4
, pp. 510-512
-
-
Saftig, P.1
Beertsen, W.2
Eskelinen, E.L.3
-
25
-
-
40149096842
-
Danon disease with typical early-onset cardiomyopathy in a male: Focus on a novel LAMP-2 mutation
-
Y. K. Bui, P. Renella, J. A. Martinez-Agosto, A. Verity, A. Madikians and J. C. Alejos, Danon disease with typical early-onset cardiomyopathy in a male: focus on a novel LAMP-2 mutation, Pediatr Transplant 12: 246-250 (2008).
-
(2008)
Pediatr Transplant
, vol.12
, pp. 246-250
-
-
Bui, Y.K.1
Renella, P.2
Martinez-Agosto, J.A.3
Verity, A.4
Madikians, A.5
Alejos, J.C.6
-
26
-
-
77953057020
-
A 13-year-old girl with proximal weakness and hypertrophic cardiomyopathy with Danon disease
-
H. Kim, A. Cho, B. C. Lim, M. J. Kim, K. J. Kim, I. Nishino, Y. S. Hwang and J. H. Chae, A 13-year-old girl with proximal weakness and hypertrophic cardiomyopathy with Danon disease, Muscle Nerve 41: 879-882 (2010).
-
(2010)
Muscle Nerve
, vol.41
, pp. 879-882
-
-
Kim, H.1
Cho, A.2
Lim, B.C.3
Kim, M.J.4
Kim, K.J.5
Nishino, I.6
Hwang, Y.S.7
Chae, J.H.8
-
27
-
-
62949091373
-
Autophagy: A lysosomal degradation pathway with a central role in health and disease
-
E. L. Eskelinen and P. Saftig, Autophagy: a lysosomal degradation pathway with a central role in health and disease, Biochim Biophys Acta 1793: 664-673 (2009).
-
(2009)
Biochim Biophys Acta
, vol.1793
, pp. 664-673
-
-
Eskelinen, E.L.1
Saftig, P.2
-
28
-
-
48249103491
-
Neurodegenerative lysosomal disorders — a continuum from development to late age
-
R. A. Nixon, D. S. Yang and J. H. Lee, Neurodegenerative lysosomal disorders — a continuum from development to late age, Autophagy 4: 590-599 (2008).
-
(2008)
Autophagy
, vol.4
, pp. 590-599
-
-
Nixon, R.A.1
Yang, D.S.2
Lee, J.H.3
-
29
-
-
0034329418
-
LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing
-
Y. Kabeya, N. Mizushima, T. Ueno, A. Yamamoto, T. Kirisako, T. Noda, E. Kominami, Y. Ohsumi and T. Yoshimori, LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing, EMBO J 19: 5720-5728 (2000).
-
(2000)
EMBO J
, vol.19
, pp. 5720-5728
-
-
Kabeya, Y.1
Mizushima, N.2
Ueno, T.3
Yamamoto, A.4
Kirisako, T.5
Noda, T.6
Kominami, E.7
Ohsumi, Y.8
Yoshimori, T.9
-
30
-
-
79551553480
-
Dissecting the dynamic turnover of GFP-LC3 in the autolysosome
-
H. M. Ni, A. Bockus, A. L. Wozniak, K. Jones, S. Weinman, X. M. Yin and W. X. Ding, Dissecting the dynamic turnover of GFP-LC3 in the autolysosome, Autophagy 7: 188-204 (2011).
-
(2011)
Autophagy
, vol.7
, pp. 188-204
-
-
Ni, H.M.1
Bockus, A.2
Wozniak, A.L.3
Jones, K.4
Weinman, S.5
Yin, X.M.6
Ding, W.X.7
-
31
-
-
38949108670
-
Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes
-
D. J. Klionsky, H. Abeliovich, P. Agostinis, D. K. Agrawal, et al., Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes, Autophagy 4: 151-175 (2007).
-
(2007)
Autophagy
, vol.4
, pp. 151-175
-
-
Klionsky, D.J.1
Abeliovich, H.2
Agostinis, P.3
Agrawal, D.K.4
-
32
-
-
33645776188
-
Dysfunction of endocytic and autophagic pathways in a lysosomal storage disease
-
T. Fukuda, L. Ewan, M. Bauer, R. J. Mattaliano, K. Zaal, E. Ralston, P. H. Plotz and N. Raben, Dysfunction of endocytic and autophagic pathways in a lysosomal storage disease, Ann Neurol 59: 700-708 (2006).
-
(2006)
Ann Neurol
, vol.59
, pp. 700-708
-
-
Fukuda, T.1
Ewan, L.2
Bauer, M.3
Mattaliano, R.J.4
Zaal, K.5
Ralston, E.6
Plotz, P.H.7
Raben, N.8
-
33
-
-
57049094929
-
Suppression of autophagy in skeletal muscle uncovers the accumulation of ubiquitinated proteins and their potential role in muscle damage in Pompe disease
-
N. Raben, V. Hill, L. Shea, S. Takikita, R. Baum, N. Mizushima, E. Ralston and P. Plotz, Suppression of autophagy in skeletal muscle uncovers the accumulation of ubiquitinated proteins and their potential role in muscle damage in Pompe disease, Hum Mol Genet 17: 3897-3908 (2008).
-
(2008)
Hum Mol Genet
, vol.17
, pp. 3897-3908
-
-
Raben, N.1
Hill, V.2
Shea, L.3
Takikita, S.4
Baum, R.5
Mizushima, N.6
Ralston, E.7
Plotz, P.8
-
34
-
-
34948909145
-
Abnormal chaperone-mediated autophagy (CMA) in cardiomyocytes of a boy with Danon disease
-
A. Fidzianska, E. Walczak and M. Walski, Abnormal chaperone-mediated autophagy (CMA) in cardiomyocytes of a boy with Danon disease, Folia Neuropathol 45: 133-139 (2007).
-
(2007)
Folia Neuropathol
, vol.45
, pp. 133-139
-
-
Fidzianska, A.1
Walczak, E.2
Walski, M.3
-
35
-
-
78549273390
-
Macroautophagy is not directly involved in the metabolism of amyloid precursor protein
-
B. Boland, D. A. Smith, D. Mooney, S. S. Jung, D. M. Walsh and F. M. Platt, Macroautophagy is not directly involved in the metabolism of amyloid precursor protein, J Biol Chem 285: 37415-37428 (2010).
-
(2010)
J Biol Chem
, vol.285
, pp. 37415-37428
-
-
Boland, B.1
Smith, D.A.2
Mooney, D.3
Jung, S.S.4
Walsh, D.M.5
Platt, F.M.6
-
36
-
-
0034666116
-
Cathepsin D deficiency induces lysosomal storage with ceroid lipofuscin in mouse CNS neurons
-
M. Koike, H. Nakanishi, P. Saftig, J. Ezaki, K. Isahara, Y. Ohsawa, W. Schulz-Schaeffer, T. Watanabe, S. Waguri, S. Kametaka, M. Shibata, K. Yamamoto, E. Kominami, C. Peters, K. von Figura and Y. Uchiyama, Cathepsin D deficiency induces lysosomal storage with ceroid lipofuscin in mouse CNS neurons, J Neurosci 20: 6898-6906 (2000).
-
(2000)
J Neurosci
, vol.20
, pp. 6898-6906
-
-
Koike, M.1
Nakanishi, H.2
Saftig, P.3
Ezaki, J.4
Isahara, K.5
Ohsawa, Y.6
Schulz-Schaeffer, W.7
Watanabe, T.8
Waguri, S.9
Kametaka, S.10
Shibata, M.11
Yamamoto, K.12
Kominami, E.13
Peters, C.14
Von Figura, K.15
Uchiyama, Y.16
-
37
-
-
28244493702
-
Participation of autophagy in storage of lysosomes in neurons from mouse models of neuronal ceroid-lipofuscinoses (Batten disease)
-
M. Koike, M. Shibata, S. Waguri, K. Yoshimura, I. Tanida, E. Kominami, T. Gotow, C. Peters, K. von Figura, N. Mizushima, P. Saftig and Y. Uchiyama, Participation of autophagy in storage of lysosomes in neurons from mouse models of neuronal ceroid-lipofuscinoses (Batten disease), Am J Pathol 167: 1713-1728 (2005).
-
(2005)
Am J Pathol
, vol.167
, pp. 1713-1728
-
-
Koike, M.1
Shibata, M.2
Waguri, S.3
Yoshimura, K.4
Tanida, I.5
Kominami, E.6
Gotow, T.7
Peters, C.8
Von Figura, K.9
Mizushima, N.10
Saftig, P.11
Uchiyama, Y.12
-
38
-
-
33745192802
-
Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice
-
T. Hara, K. Nakamura, M. Matsui, A. Yamamoto, Y. Nakahara, R. Suzuki-Migishima, M. Yokoyama, K. Mishima, I. Saito, H. Okano and N. Mizushima, Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice, Nature 441: 885-889 (2006).
-
(2006)
Nature
, vol.441
, pp. 885-889
-
-
Hara, T.1
Nakamura, K.2
Matsui, M.3
Yamamoto, A.4
Nakahara, Y.5
Suzuki-Migishima, R.6
Yokoyama, M.7
Mishima, K.8
Saito, I.9
Okano, H.10
Mizushima, N.11
-
39
-
-
27944504351
-
P62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death
-
G. Bj0rk0y, T. Lamark, A. Brech, H. Outzen, M. Perander, A. 0vervatn, H. Stenmark and T. Johansen, p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death, J Cell Biol 171: 603-614 (2005).
-
(2005)
J Cell Biol
, vol.171
, pp. 603-614
-
-
Bj0rk0y, G.1
Lamark, T.2
Brech, A.3
Outzen, H.4
Perander, M.5
Overvatn, A.6
Stenmark, H.7
Johansen, T.8
-
40
-
-
77958185918
-
Saposin C mutations in Gaucher disease patients resulting in lysosomal lipid accumulation, saposin C deficiency, but normal prosaposin processing and sorting
-
A. M. Vaccaro, M. Motta, M. Tatti, S. Scarpa, L. Masuelli, M. Bhat, M. T. Vanier, A. Tylki-Szymanska and R. Salvioli, Saposin C mutations in Gaucher disease patients resulting in lysosomal lipid accumulation, saposin C deficiency, but normal prosaposin processing and sorting, Hum Mol Genet 19: 2987-2997 (2010).
-
(2010)
Hum Mol Genet
, vol.19
, pp. 2987-2997
-
-
Vaccaro, A.M.1
Motta, M.2
Tatti, M.3
Scarpa, S.4
Masuelli, L.5
Bhat, M.6
Vanier, M.T.7
Tylki-Szymanska, A.8
Salvioli, R.9
-
41
-
-
50249095558
-
Mucolipidosis type IV: The importance of functional lysosomes for efficient autophagy
-
S. Vergarajauregui and R. Puertollano, Mucolipidosis type IV: the importance of functional lysosomes for efficient autophagy, Autophagy 4: 832-834 (2008).
-
(2008)
Autophagy
, vol.4
, pp. 832-834
-
-
Vergarajauregui, S.1
Puertollano, R.2
-
42
-
-
34548860918
-
Cholesterol accumulation is associated with lysosomal dysfunction and autophagic stress in Npc1 -/- mouse brain
-
G. Liao, Y. Yao, J. Liu, Z. Yu, S. Cheung, A. Xie, X. Liang and X. Bi, Cholesterol accumulation is associated with lysosomal dysfunction and autophagic stress in Npc1 -/- mouse brain, Am J Pathol 171: 962-975 (2007).
-
(2007)
Am J Pathol
, vol.171
, pp. 962-975
-
-
Liao, G.1
Yao, Y.2
Liu, J.3
Yu, Z.4
Cheung, S.5
Xie, A.6
Liang, X.7
Bi, X.8
-
43
-
-
79955694568
-
Lysosomal enzyme cathepsin D protects against alpha-synuclein aggregation and toxicity
-
L. Qiao, S. Hamamichi, K. A. Caldwell, G. A. Caldwell, T. A. Yacoubian, S. Wilson, Z. L. Xie, L. D. Speake, R. Parks, D. Crabtree, Q. Liang, S. Crimmins, L. Schneider, Y. Uchiyama, T. Iwatsubo, Y. Zhou, L. Peng, Y. Lu, D. G. Standaert, K. C. Walls, J. J. Shacka, K. A. Roth and J. Zhang, Lysosomal enzyme cathepsin D protects against alpha-synuclein aggregation and toxicity, Mol Brain 1: 1-18 (2008).
-
(2008)
Mol Brain
, vol.1
, pp. 1-18
-
-
Qiao, L.1
Hamamichi, S.2
Caldwell, K.A.3
Caldwell, G.A.4
Yacoubian, T.A.5
Wilson, S.6
Xie, Z.L.7
Speake, L.D.8
Parks, R.9
Crabtree, D.10
Liang, Q.11
Crimmins, S.12
Schneider, L.13
Uchiyama, Y.14
Iwatsubo, T.15
Zhou, Y.16
Peng, L.17
Lu, Y.18
Standaert, D.G.19
Walls, K.C.20
Shacka, J.J.21
Roth, K.A.22
Zhang, J.23
more..
-
44
-
-
64949185378
-
Cathepsin D expression level affects alpha-synuclein processing, aggregation, and toxicity in vivo
-
V. Cullen, M. Lindfors, J. Ng, A. Paetau, E. Swinton, P. Kolodziej, H. Boston, P. Saftig, J. Woulfe, M. B. Feany, L. Myllykangas, M. G. Schlossmacher and J. Tyynela, Cathepsin D expression level affects alpha-synuclein processing, aggregation, and toxicity in vivo, Mol Brain 2: 1-17 (2009).
-
(2009)
Mol Brain
, vol.2
, pp. 1-17
-
-
Cullen, V.1
Lindfors, M.2
Ng, J.3
Paetau, A.4
Swinton, E.5
Kolodziej, P.6
Boston, H.7
Saftig, P.8
Woulfe, J.9
Feany, M.B.10
Myllykangas, L.11
Schlossmacher, M.G.12
Tyynela, J.13
-
45
-
-
34447302577
-
Autophagy in Niemann-Pick C disease is dependent upon Beclin-1 and responsive to lipid trafficking defects
-
C. D. Pacheco, R. Kunkel and A. P. Lieberman, Autophagy in Niemann-Pick C disease is dependent upon Beclin-1 and responsive to lipid trafficking defects, Hum Mol Genet 16: 1495-1503 (2007).
-
(2007)
Hum Mol Genet
, vol.16
, pp. 1495-1503
-
-
Pacheco, C.D.1
Kunkel, R.2
Lieberman, A.P.3
-
46
-
-
35848967804
-
How to interpret LC3 immunoblotting
-
N. Mizushima and T. Yoshimori, How to interpret LC3 immunoblotting, Autophagy 3: 542-545 (2007).
-
(2007)
Autophagy
, vol.3
, pp. 542-545
-
-
Mizushima, N.1
Yoshimori, T.2
-
47
-
-
37549066697
-
A block of autophagy in lysosomal storage disorders
-
C. Settembre, A. Fraldi, L. Jahreiss, C. Spampanato, C. Venturi, D. Medina, R. de Pablo, C. Tacchetti, D. C. Rubinsztein and A. Ballabio, A block of autophagy in lysosomal storage disorders, Hum Mol Genet 17: 119-129 (2007).
-
(2007)
Hum Mol Genet
, vol.17
, pp. 119-129
-
-
Settembre, C.1
Fraldi, A.2
Jahreiss, L.3
Spampanato, C.4
Venturi, C.5
Medina, D.6
De Pablo, R.7
Tacchetti, C.8
Rubinsztein, D.C.9
Ballabio, A.10
-
48
-
-
2442522365
-
Salicylihalamide A inhibits the V0 sector of the V-ATPase through a mechanism distinct from bafilomycin A1
-
X. S. Xie, D. Padron, X. Liao, J. Wang, M. G. Roth and J. K. de Brabander, Salicylihalamide A inhibits the V0 sector of the V-ATPase through a mechanism distinct from bafilomycin A1, J Biol Chem 279: 19755-19763 (2004).
-
(2004)
J Biol Chem
, vol.279
, pp. 19755-19763
-
-
Xie, X.S.1
Padron, D.2
Liao, X.3
Wang, J.4
Roth, M.G.5
De Brabander, J.K.6
-
49
-
-
78649288882
-
Suppression of autophagy permits successful enzyme replacement therapy in a lysosomal storage disorder-murine Pompe disease
-
N. Raben, C. Schreiner, R. Baum, S. Takikita, S. Xu, T. Xie, R. Myerowitz, M. Komatsu, J. H. Van Der Meulen, K. Nagaraju, E. Ralston and P. H. Plotz, Suppression of autophagy permits successful enzyme replacement therapy in a lysosomal storage disorder-murine Pompe disease, Autophagy 6: 1078-1089 (2010).
-
(2010)
Autophagy
, vol.6
, pp. 1078-1089
-
-
Raben, N.1
Schreiner, C.2
Baum, R.3
Takikita, S.4
Xu, S.5
Xie, T.6
Myerowitz, R.7
Komatsu, M.8
Van Der Meulen, J.H.9
Nagaraju, K.10
Ralston, E.11
Plotz, P.H.12
-
50
-
-
33745976466
-
Autophagy is disrupted in a knock-in mouse model of juvenile neuronal ceroid lipofuscinosis
-
Y. Cao, J. A. Espinola, E. Fossale, A. C. Massey, A. M. Cuervo, M. E. MacDonald and S. L. Cotman, Autophagy is disrupted in a knock-in mouse model of juvenile neuronal ceroid lipofuscinosis, J Biol Chem 281: 20483-20493 (2006).
-
(2006)
J Biol Chem
, vol.281
, pp. 20483-20493
-
-
Cao, Y.1
Espinola, J.A.2
Fossale, E.3
Massey, A.C.4
Cuervo, A.M.5
Macdonald, M.E.6
Cotman, S.L.7
-
51
-
-
24644471460
-
Cell death pathways in juvenile Batten disease
-
D. A. Persaud-Sawin and R. M. Boustany, Cell death pathways in juvenile Batten disease, Apoptosis 10: 973-985 (2005).
-
(2005)
Apoptosis
, vol.10
, pp. 973-985
-
-
Persaud-Sawin, D.A.1
Boustany, R.M.2
-
52
-
-
78651265495
-
Sphingosine-1-phosphate phosphohydrolase-1 regulates ER stress-induced autophagy
-
S. Lepine, J. C. Allegood, M. Park, P. Dent, S. Milstien and S. Spiegel, Sphingosine-1-phosphate phosphohydrolase-1 regulates ER stress-induced autophagy, Cell Death Differ 18: 350-361 (2010).
-
(2010)
Cell Death Differ
, vol.18
, pp. 350-361
-
-
Lepine, S.1
Allegood, J.C.2
Park, M.3
Dent, P.4
Milstien, S.5
Spiegel, S.6
-
53
-
-
77953699711
-
Termination of autophagy and reformation of lysosomes regulated by mTOR
-
L. Yu, C. K. McPhee, L. Zheng, G. A. Mardones, Y. Rong, J. Peng, N. Mi, Y. Zhao, Z. Liu, F. Wan, D. W. Hailey, V. Oorschot, J. Klumperman, E. H. Baehrecke and M. J. Lenardo, Termination of autophagy and reformation of lysosomes regulated by mTOR, Nature 465: 942-946 (2010).
-
(2010)
Nature
, vol.465
, pp. 942-946
-
-
Yu, L.1
Mc Phee, C.K.2
Zheng, L.3
Mardones, G.A.4
Rong, Y.5
Peng, J.6
Mi, N.7
Zhao, Y.8
Liu, Z.9
Wan, F.10
Hailey, D.W.11
Oorschot, V.12
Klumperman, J.13
Baehrecke, E.H.14
Lenardo, M.J.15
-
54
-
-
69349090907
-
The cellular pathways of neuronal autophagy and their implication in neurodegenerative diseases
-
Z. Yue, L. Friedman, M. Komatsu and K. Tanaka, The cellular pathways of neuronal autophagy and their implication in neurodegenerative diseases, Biochim Biophys Acta 1793: 1496-1507 (2009).
-
(2009)
Biochim Biophys Acta
, vol.1793
, pp. 1496-1507
-
-
Yue, Z.1
Friedman, L.2
Komatsu, M.3
Tanaka, K.4
-
55
-
-
77951249136
-
Lysosome dysfunction triggers Atg7-dependent neural apoptosis
-
K. C. Walls, A. P. Ghosh, A. V. Franklin, B. J. Klocke, M. Ballestas, J. J. Shacka, J. Zhang and K. A. Roth, Lysosome dysfunction triggers Atg7-dependent neural apoptosis, J Biol Chem 285: 10497-10507 (2010).
-
(2010)
J Biol Chem
, vol.285
, pp. 10497-10507
-
-
Walls, K.C.1
Ghosh, A.P.2
Franklin, A.V.3
Klocke, B.J.4
Ballestas, M.5
Shacka, J.J.6
Zhang, J.7
Roth, K.A.8
-
56
-
-
33751014016
-
Autophagy and mistargeting of therapeutic enzyme in skeletal muscle in Pompe disease
-
T. Fukuda, M. Ahearn, A. Roberts, R. J. Mattaliano, K. Zaal, E. Ralston, P. H. Plotz and N. Raben, Autophagy and mistargeting of therapeutic enzyme in skeletal muscle in Pompe disease, Mol Ther 14: 831-839 (2006).
-
(2006)
Mol Ther
, vol.14
, pp. 831-839
-
-
Fukuda, T.1
Ahearn, M.2
Roberts, A.3
Mattaliano, R.J.4
Zaal, K.5
Ralston, E.6
Plotz, P.H.7
Raben, N.8
-
57
-
-
0023760665
-
The new stereological tools: Disector, fractionator, nucleator and point sampled intercepts and their use in pathological research and diagnosis
-
H. J. Gundersen, P. Bagger, T. F. Bendtsen, S. M. Evans, et al., The new stereological tools: disector, fractionator, nucleator and point sampled intercepts and their use in pathological research and diagnosis, APMIS 96: 857-881 (1988).
-
(1988)
APMIS
, vol.96
, pp. 857-881
-
-
Gundersen, H.J.1
Bagger, P.2
Bendtsen, T.F.3
Evans, S.M.4
-
58
-
-
67349202845
-
Allopregnanolone treatment delays cholesterol accumulation and reduces autophagic/lysosomal dysfunction and inflammation in Npc1-/- mouse brain
-
G. Liao, S. Cheung, J. Galeano, A. X. Ji, Q. Qin and X. Bi, Allopregnanolone treatment delays cholesterol accumulation and reduces autophagic/lysosomal dysfunction and inflammation in Npc1-/- mouse brain, Brain Res 1270: 140-151 (2009).
-
(2009)
Brain Res
, vol.1270
, pp. 140-151
-
-
Liao, G.1
Cheung, S.2
Galeano, J.3
Ji, A.X.4
Qin, Q.5
Bi, X.6
-
59
-
-
77951217000
-
Dual role of 3-methyladenine in modulation of autophagy via different temporal patterns of inhibition on class I and III phosphoinositide 3-kinase
-
Y. T. Wu, H. L. Tan, G. Shui, C. Bauvy, Q. Huang, M. R. Wenk, C. N. Ong, P. Codogno and H. M. Shen, Dual role of 3-methyladenine in modulation of autophagy via different temporal patterns of inhibition on class I and III phosphoinositide 3-kinase, J Biol Chem 285: 10850-10861 (2010).
-
(2010)
J Biol Chem
, vol.285
, pp. 10850-10861
-
-
Wu, Y.T.1
Tan, H.L.2
Shui, G.3
Bauvy, C.4
Huang, Q.5
Wenk, M.R.6
Ong, C.N.7
Codogno, P.8
Shen, H.M.9
-
60
-
-
33646419529
-
Over-expression of CLN3P, the Batten disease protein, inhibits PANDER-induced apoptosis in neuroblastoma cells: Further evidence that CLN3P has anti-apoptotic properties
-
S. B. Narayan, D. Rakheja, J. V. Pastor, K. Rosenblatt, S. R. Greene, J. Yang, B. A. Wolf and M. J. Bennett, Over-expression of CLN3P, the Batten disease protein, inhibits PANDER-induced apoptosis in neuroblastoma cells: Further evidence that CLN3P has anti-apoptotic properties, Mol Genet Metab 88: 178-183 (2006).
-
(2006)
Mol Genet Metab
, vol.88
, pp. 178-183
-
-
Narayan, S.B.1
Rakheja, D.2
Pastor, J.V.3
Rosenblatt, K.4
Greene, S.R.5
Yang, J.6
Wolf, B.A.7
Bennett, M.J.8
-
61
-
-
67749122634
-
A gene network regulating lysosomal biogenesis and function
-
M. Sardiello, M. Palmieri, A. di Ronza, D. L. Medina, M. Valenza, V. A. Gennarino, C. Di Malta, F. Donaudy, V. Embrione, R. S. Polishchuk, S. Banfi, G. Parenti, E. Cattaneo and A. Ballabio, A gene network regulating lysosomal biogenesis and function, Science 325: 473-477 (2009).
-
(2009)
Science
, vol.325
, pp. 473-477
-
-
Sardiello, M.1
Palmieri, M.2
Di Ronza, A.3
Medina, D.L.4
Valenza, M.5
Gennarino, V.A.6
Di Malta, C.7
Donaudy, F.8
Embrione, V.9
Polishchuk, R.S.10
Banfi, S.11
Parenti, G.12
Cattaneo, E.13
Ballabio, A.14
-
62
-
-
74849083093
-
Lysosomal enhancement: A CLEAR answer to cellular degradative needs
-
M. Sardiello and A. Ballabio, Lysosomal enhancement: a CLEAR answer to cellular degradative needs, Cell Cycle 8: 4021-4022 (2009).
-
(2009)
Cell Cycle
, vol.8
, pp. 4021-4022
-
-
Sardiello, M.1
Ballabio, A.2
-
63
-
-
77956855813
-
Pathogenic lysosomal depletion in Parkinson’s disease
-
B. Dehay, J. Bove, N. Rodriguez-Muela, C. Perier, A. Recasens, P. Boya and M. Vila, Pathogenic lysosomal depletion in Parkinson’s disease, J Neurosci 30: 12535-12544 (2010).
-
(2010)
J Neurosci
, vol.30
, pp. 12535-12544
-
-
Dehay, B.1
Bove, J.2
Rodriguez-Muela, N.3
Perier, C.4
Recasens, A.5
Boya, P.6
Vila, M.7
-
64
-
-
39449083733
-
Antioxidants and free radical scavengers for the treatment of stroke, traumatic brain injury and aging
-
J. E. Slemmer, J. J. Shacka, M. I. Sweeney and J. T. Weber, Antioxidants and free radical scavengers for the treatment of stroke, traumatic brain injury and aging, Curr Med Chem 15: 404-414 (2008).
-
(2008)
Curr Med Chem
, vol.15
, pp. 404-414
-
-
Slemmer, J.E.1
Shacka, J.J.2
Sweeney, M.I.3
Weber, J.T.4
-
65
-
-
58849163098
-
Oxidative stress and autophagy in the regulation of lysosome-dependent neuron death
-
V. N. Pivtoraiko, S. L. Stone, K. A. Roth and J. J. Shacka, Oxidative stress and autophagy in the regulation of lysosome-dependent neuron death, Antioxid Redox Signal 11: 481-496 (2009).
-
(2009)
Antioxid Redox Signal
, vol.11
, pp. 481-496
-
-
Pivtoraiko, V.N.1
Stone, S.L.2
Roth, K.A.3
Shacka, J.J.4
-
66
-
-
34250016055
-
Apoptotic neuronal death in Parkinson’s disease: Involvement of nitric oxide
-
S. Singh and M. Dikshit, Apoptotic neuronal death in Parkinson’s disease: involvement of nitric oxide, Brain Res Rev 54: 233-250 (2007).
-
(2007)
Brain Res Rev
, vol.54
, pp. 233-250
-
-
Singh, S.1
Dikshit, M.2
-
67
-
-
0028929548
-
Neurofibrillary tangles in Niemann-Pick disease type C
-
S. Love, L. R. Bridges and C. P. Case, Neurofibrillary tangles in Niemann-Pick disease type C, Brain 118(Pt 1): 119-129 (1995).
-
(1995)
Brain
, vol.118
, pp. 119-129
-
-
Love, S.1
Bridges, L.R.2
Case, C.P.3
-
68
-
-
56349119573
-
Motor deficit in a Drosophila model of mucolipidosis type IV due to defective clearance of apoptotic cells
-
K. Venkatachalam, A. A. Long, R. Elsaesser, D. Nikolaeva, K. Broadie and C. Montell, Motor deficit in a Drosophila model of mucolipidosis type IV due to defective clearance of apoptotic cells, Cell 135: 838-851 (2008).
-
(2008)
Cell
, vol.135
, pp. 838-851
-
-
Venkatachalam, K.1
Long, A.A.2
Elsaesser, R.3
Nikolaeva, D.4
Broadie, K.5
Montell, C.6
-
69
-
-
0035478732
-
Involvement of nitric oxide released from microglia-macrophages in pathological changes of cathepsin D-deficient mice
-
H. Nakanishi, J. Zhang, M. Koike, T. Nishioku, Y. Okamoto, E. Kominami, K. von Figura, C. Peters, K. Yamamoto, P. Saftig and Y. Uchiyama, Involvement of nitric oxide released from microglia-macrophages in pathological changes of cathepsin D-deficient mice, J Neurosci 21: 7526-7533 (2001).
-
(2001)
J Neurosci
, vol.21
, pp. 7526-7533
-
-
Nakanishi, H.1
Zhang, J.2
Koike, M.3
Nishioku, T.4
Okamoto, Y.5
Kominami, E.6
Von Figura, K.7
Peters, C.8
Yamamoto, K.9
Saftig, P.10
Uchiyama, Y.11
-
70
-
-
60549091933
-
Tau deletion exacerbates the phenotype of Niemann-Pick type C mice and implicates autophagy in pathogenesis
-
C. D. Pacheco, M. J. Elrick and A. P. Lieberman, Tau deletion exacerbates the phenotype of Niemann-Pick type C mice and implicates autophagy in pathogenesis, Hum Mol Genet 18: 956-965 (2009).
-
(2009)
Hum Mol Genet
, vol.18
, pp. 956-965
-
-
Pacheco, C.D.1
Elrick, M.J.2
Lieberman, A.P.3
-
71
-
-
77957340035
-
Lysosomal dysfunction promotes cleavage and neurotoxicity of tau
-
V. Khurana, I. Elson-Schwab, T. A. Fulga, K. A. Sharp, C. A. Loewen, E. Mulkearns, J. Tyynela, C. R. Scherzer and M. B. Feany, Lysosomal dysfunction promotes cleavage and neurotoxicity of tau in vivo, PLoS Genet 6: e1001026 (2010).
-
(2010)
In Vivo, Plos Genet
, vol.6
-
-
Khurana, V.1
Elson-Schwab, I.2
Fulga, T.A.3
Sharp, K.A.4
Loewen, C.A.5
Mulkearns, E.6
Tyynela, J.7
Scherzer, C.R.8
Feany, M.B.9
-
72
-
-
0037301337
-
Involvement of two different cell death pathways in retinal atrophy of cathepsin D-deficient mice
-
M. Koike, M. Shibata, Y. Ohsawa, H. Nakanishi, T. Koga, S. Kametaka, S. Waguri, T. Momoi, E. Kominami, C. Peters, K. von Figura, P. Saftig and Y. Uchiyama, Involvement of two different cell death pathways in retinal atrophy of cathepsin D-deficient mice, Mol Cell Neurosci 22: 146-161 (2003).
-
(2003)
Mol Cell Neurosci
, vol.22
, pp. 146-161
-
-
Koike, M.1
Shibata, M.2
Ohsawa, Y.3
Nakanishi, H.4
Koga, T.5
Kametaka, S.6
Waguri, S.7
Momoi, T.8
Kominami, E.9
Peters, C.10
Von Figura, K.11
Saftig, P.12
Uchiyama, Y.13
-
73
-
-
34248593481
-
Altered regulation of phosphatidylinositol 3-kinase signaling in cathep-sin D-deficient brain
-
K. C. Walls, B. J. Klocke, P. Saftig, M. Shibata, Y. Uchiyama, K. A. Roth and J. J. Shacka, Altered regulation of phosphatidylinositol 3-kinase signaling in cathep-sin D-deficient brain, Autophagy 3: 222-229 (2007).
-
(2007)
Autophagy
, vol.3
, pp. 222-229
-
-
Walls, K.C.1
Klocke, B.J.2
Saftig, P.3
Shibata, M.4
Uchiyama, Y.5
Roth, K.A.6
Shacka, J.J.7
-
74
-
-
33847215777
-
Cathepsin D deficiency induces persistent neurodegeneration in the absence of Bax-dependent apoptosis
-
J. J. Shacka, B. J. Klocke, C. Young, M. Shibata, J. W. Olney, Y. Uchiyama, P. Saftig and K. A. Roth, Cathepsin D deficiency induces persistent neurodegeneration in the absence of Bax-dependent apoptosis, J Neurosci 27: 2081-2090 (2007).
-
(2007)
J Neurosci
, vol.27
, pp. 2081-2090
-
-
Shacka, J.J.1
Klocke, B.J.2
Young, C.3
Shibata, M.4
Olney, J.W.5
Uchiyama, Y.6
Saftig, P.7
Roth, K.A.8
-
75
-
-
51549106105
-
Cathepsin D is the main lysosomal enzyme involved in the degradation of alpha-synuclein and generation of its carboxy-terminally truncated species
-
D. Sevlever, P. Jiang and S. H. Yen, Cathepsin D is the main lysosomal enzyme involved in the degradation of alpha-synuclein and generation of its carboxy-terminally truncated species, Biochemistry 47: 9678-9687 (2008).
-
(2008)
Biochemistry
, vol.47
, pp. 9678-9687
-
-
Sevlever, D.1
Jiang, P.2
Yen, S.H.3
-
76
-
-
58149215720
-
Regulation of neuronal survival factor MEF2D by chaperone-mediated autophagy
-
Q. Yang, H. She, M. Gearing, E. Colla, M. Lee, J. J. Shacka and Z. Mao, Regulation of neuronal survival factor MEF2D by chaperone-mediated autophagy, Science 323: 124-127 (2009).
-
(2009)
Science
, vol.323
, pp. 124-127
-
-
Yang, Q.1
She, H.2
Gearing, M.3
Colla, E.4
Lee, M.5
Shacka, J.J.6
Mao, Z.7
-
77
-
-
66249109910
-
Mutations for Gaucher disease confer high susceptibility to Parkinson disease
-
J. Mitsui, I. Mizuta, A. Toyoda, R. Ashida, Y. Takahashi, J. Goto, Y. Fukuda, H. Date, A. Iwata, M. Yamamoto, N. Hattori, M. Murata, T. Toda and S. Tsuji, Mutations for Gaucher disease confer high susceptibility to Parkinson disease, Arch Neurol 66: 571-576 (2009).
-
(2009)
Arch Neurol
, vol.66
, pp. 571-576
-
-
Mitsui, J.1
Mizuta, I.2
Toyoda, A.3
Ashida, R.4
Takahashi, Y.5
Goto, J.6
Fukuda, Y.7
Date, H.8
Iwata, A.9
Yamamoto, M.10
Hattori, N.11
Murata, M.12
Toda, T.13
Tsuji, S.14
-
79
-
-
79952619654
-
Accumulation and distribution of alpha-synuclein and ubiquitin in the CNS of Gaucher disease mouse models
-
Y. H. Xu, Y. Sun, H. Ran, B. Quinn, D. Witte and G. A. Grabowski, Accumulation and distribution of alpha-synuclein and ubiquitin in the CNS of Gaucher disease mouse models, Mol Genet Metab 102: 436-447 (2011).
-
(2011)
Mol Genet Metab
, vol.102
, pp. 436-447
-
-
Xu, Y.H.1
Sun, Y.2
Ran, H.3
Quinn, B.4
Witte, D.5
Grabowski, G.A.6
-
80
-
-
78149410222
-
Glucocerebrosidase is present in alpha-synuclein inclusions in Lewy body disorders
-
O. Goker-Alpan, B. K. Stubblefield, B. I. Giasson and E. Sidransky, Glucocerebrosidase is present in alpha-synuclein inclusions in Lewy body disorders, Acta Neuropathol 120: 641-649 (2010).
-
(2010)
Acta Neuropathol
, vol.120
, pp. 641-649
-
-
Goker-Alpan, O.1
Stubblefield, B.K.2
Giasson, B.I.3
Sidransky, E.4
-
81
-
-
38449091923
-
The autophagy-lysosomal degradation pathway: Role in neurodegenerative disease and therapy
-
J. J. Shacka, K. A. Roth and J. Zhang, The autophagy-lysosomal degradation pathway: role in neurodegenerative disease and therapy, Front Biosci 13: 718-736 (2008).
-
(2008)
Front Biosci
, vol.13
, pp. 718-736
-
-
Shacka, J.J.1
Roth, K.A.2
Zhang, J.3
-
82
-
-
77954715959
-
Low-dose bafilomycin attenuates neuronal cell death associated with autophagy-lysosome pathway dysfunction
-
V. N. Pivtoraiko, A. J. Harrington, B. J. Mader, A. M. Luker, G. A. Caldwell, K. A. Caldwell, K. A. Roth and J. J. Shacka, Low-dose bafilomycin attenuates neuronal cell death associated with autophagy-lysosome pathway dysfunction, J Neurochem 114: 1193-1204 (2010).
-
(2010)
J Neurochem
, vol.114
, pp. 1193-1204
-
-
Pivtoraiko, V.N.1
Harrington, A.J.2
Mader, B.J.3
Luker, A.M.4
Caldwell, G.A.5
Caldwell, K.A.6
Roth, K.A.7
Shacka, J.J.8
-
83
-
-
0029970783
-
Amyloidogenic processing of human amyloid precursor protein in hippocampal neurons devoid of cathepsin D
-
P. Saftig, C. Peters, K. von Figura, K. Craessaerts, F. Van Leuven and B. De Strooper, Amyloidogenic processing of human amyloid precursor protein in hippocampal neurons devoid of cathepsin D, J Biol Chem 271: 27241-27244 (1996).
-
(1996)
J Biol Chem
, vol.271
, pp. 27241-27244
-
-
Saftig, P.1
Peters, C.2
Von Figura, K.3
Craessaerts, K.4
Van Leuven, F.5
De Strooper, B.6
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