메뉴 건너뛰기




Volumn 50, Issue 2, 2016, Pages 477-489

Diminished CRE-induced plasticity is linked to memory deficits in familial Alzheimer's disease mice

Author keywords

Alzheimer's disease; CBP; CRE; CREB; hippocampal plasticity; learning and memory

Indexed keywords

BETA GALACTOSIDASE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN; HISTONE ACETYLTRANSFERASE PCAF; CREB1 PROTEIN, MOUSE;

EID: 84970937544     PISSN: 13872877     EISSN: 18758908     Source Type: Journal    
DOI: 10.3233/JAD-150650     Document Type: Article
Times cited : (44)

References (57)
  • 1
    • 84862829155 scopus 로고    scopus 로고
    • Memory enhancement: Consolidation, reconsolidation and insulin-like growth factor 2
    • Alberini CM, Chen DY. (2012). Memory enhancement: consolidation, reconsolidation and insulin-like growth factor 2. Trends Neurosci 35, 274-283
    • (2012) Trends Neurosci , vol.35 , pp. 274-283
    • Alberini, C.M.1    Chen, D.Y.2
  • 2
    • 58549090329 scopus 로고    scopus 로고
    • The molecular and cellular biology of enhanced cognition
    • Lee YS, Silva AJ. (2009). The molecular and cellular biology of enhanced cognition. Nat Rev Neurosci 10, 126-140
    • (2009) Nat Rev Neurosci , vol.10 , pp. 126-140
    • Lee, Y.S.1    Silva, A.J.2
  • 3
    • 79751536786 scopus 로고    scopus 로고
    • Molecular mechanisms for the destabilization and restabilization of reactivated spatial memory in the Morris water maze
    • Kim R, Moki R, Kida S. (2011). Molecular mechanisms for the destabilization and restabilization of reactivated spatial memory in the Morris water maze. Mol Brain 4, 9
    • (2011) Mol Brain , vol.4 , pp. 9
    • Kim, R.1    Moki, R.2    Kida, S.3
  • 5
    • 0037130346 scopus 로고    scopus 로고
    • CREB phosphorylation as a molecular marker of memory processing in the hippocampus for spatial learning
    • Mizuno M, Yamada K, Maekawa N, Saito K, Seishima M, Nabeshima T. (2002). CREB phosphorylation as a molecular marker of memory processing in the hippocampus for spatial learning. Behav Brain Res 133, 135-141
    • (2002) Behav Brain Res , vol.133 , pp. 135-141
    • Mizuno, M.1    Yamada, K.2    Maekawa, N.3    Saito, K.4    Seishima, M.5    Nabeshima, T.6
  • 6
    • 80051791713 scopus 로고    scopus 로고
    • Downregulation of CREB expression in Alzheimer's brain and in A beta-Treated rat hippocampal neurons
    • Pugazhenthi S, Wang MR, Pham S, Sze CI, Eckman CB. (2011). Downregulation of CREB expression in Alzheimer's brain and in A beta-Treated rat hippocampal neurons. Mol Neurodegener 6, 60
    • (2011) Mol Neurodegener , vol.6 , pp. 60
    • Pugazhenthi, S.1    Wang, M.R.2    Pham, S.3    Sze, C.I.4    Eckman, C.B.5
  • 7
    • 0033541589 scopus 로고    scopus 로고
    • Impaired phosphorylation of cyclic AMP response element binding protein in the hippocampus of dementia of the Alzheimer type
    • Yamamoto-Sasaki M, Ozawa H, Saito T, Rosler M, Riederer P. (1999). Impaired phosphorylation of cyclic AMP response element binding protein in the hippocampus of dementia of the Alzheimer type. Brain Res 824, 300-303
    • (1999) Brain Res , vol.824 , pp. 300-303
    • Yamamoto-Sasaki, M.1    Ozawa, H.2    Saito, T.3    Rosler, M.4    Riederer, P.5
  • 8
    • 0030463305 scopus 로고    scopus 로고
    • Reduced immunoreactivity of adenylyl cyclase in dementia of the Alzheimer type
    • Yamamoto M, Ozawa H, Saito T, Frolich L, Riederer P, Takahata N. (1996). Reduced immunoreactivity of adenylyl cyclase in dementia of the Alzheimer type. Neuroreport 7, 2965-2970
    • (1996) Neuroreport , vol.7 , pp. 2965-2970
    • Yamamoto, M.1    Ozawa, H.2    Saito, T.3    Frolich, L.4    Riederer, P.5    Takahata, N.6
  • 9
    • 0030608638 scopus 로고    scopus 로고
    • Ca2+/CaM-sensitive adenylyl cyclase activity is decreased in the Alzheimer's brain: Possible relation to type i adenylyl cyclase
    • Yamamoto M, Ozawa H, Saito T, Hatta S, Riederer P, Takahata N. (1997). Ca2+/CaM-sensitive adenylyl cyclase activity is decreased in the Alzheimer's brain: possible relation to type I adenylyl cyclase. J Neural Transm 104, 721-732
    • (1997) J Neural Transm , vol.104 , pp. 721-732
    • Yamamoto, M.1    Ozawa, H.2    Saito, T.3    Hatta, S.4    Riederer, P.5    Takahata, N.6
  • 10
    • 0026550678 scopus 로고
    • Adenylyl cyclase activity in postmortem human brain - evidence of altered g-protein mediation in Alzheimer's disease
    • Cowburn RF, Oneill C, Ravid R, Alafuzoff I, Winblad B, Fowler CJ. (1992). Adenylyl cyclase activity in postmortem human brain - evidence of altered g-protein mediation in Alzheimer's disease. J Neurochem 58, 1409-1419
    • (1992) J Neurochem , vol.58 , pp. 1409-1419
    • Cowburn, R.F.1    Oneill, C.2    Ravid, R.3    Alafuzoff, I.4    Winblad, B.5    Fowler, C.J.6
  • 11
    • 0028224211 scopus 로고
    • Adenylyl-cyclase activity in Alzheimer's disease brain-stimulatory and inhibitory signal-Transduction pathways are differently affected
    • Schnecko A, Witte K, Bohl J, Ohm T, Lemmer B. (1994). Adenylyl-cyclase activity in Alzheimer's disease brain-stimulatory and inhibitory signal-Transduction pathways are differently affected. Brain Res 644, 291-296
    • (1994) Brain Res , vol.644 , pp. 291-296
    • Schnecko, A.1    Witte, K.2    Bohl, J.3    Ohm, T.4    Lemmer, B.5
  • 13
    • 0141429160 scopus 로고    scopus 로고
    • A CBP binding transcriptional repressor produced by the PS1/epsilon-cleavage of N-cadherin is inhibited by PS1 FAD mutations
    • Marambaud P, Wen PH, Dutt A, Shioi J, Takashima A, Siman R, Robakis NK. (2003). A CBP binding transcriptional repressor produced by the PS1/epsilon-cleavage of N-cadherin is inhibited by PS1 FAD mutations. Cell 114, 635-645
    • (2003) Cell , vol.114 , pp. 635-645
    • Marambaud, P.1    Wen, P.H.2    Dutt, A.3    Shioi, J.4    Takashima, A.5    Siman, R.6    Robakis, N.K.7
  • 14
    • 33745048523 scopus 로고    scopus 로고
    • CREBbinding protein activation by presenilin 1 but not by its M146L mutant
    • Francis YI, Stephanou A, Latchman DS. (2006). CREBbinding protein activation by presenilin 1 but not by its M146L mutant. Neuroreport 17, 917-921
    • (2006) Neuroreport , vol.17 , pp. 917-921
    • Francis, Y.I.1    Stephanou, A.2    Latchman, D.S.3
  • 16
    • 78651072485 scopus 로고    scopus 로고
    • CBP gene transfer increases BDNF levels and ameliorates learning and memory deficits in a mouse model of Alzheimer's disease
    • Caccamo A, Maldonado MA, Bokov AF, Majumder S, Oddo S. (2010). CBP gene transfer increases BDNF levels and ameliorates learning and memory deficits in a mouse model of Alzheimer's disease. Proc Natl Acad Sci U S A 107, 22687-22692
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 22687-22692
    • Caccamo, A.1    Maldonado, M.A.2    Bokov, A.F.3    Majumder, S.4    Oddo, S.5
  • 21
    • 0035875962 scopus 로고    scopus 로고
    • Beta-Amyloid activates the mitogen-Activated protein kinase cascade via hippocampal alpha7 nicotinic acetylcholine receptors: In vitro and in vivo mechanisms related to Alzheimer's disease
    • Dineley KT, Westerman M, Bui D, Bell K, Ashe KH, Sweatt JD. (2001). Beta-Amyloid activates the mitogen-Activated protein kinase cascade via hippocampal alpha7 nicotinic acetylcholine receptors: In vitro and in vivo mechanisms related to Alzheimer's disease. J Neurosci 21, 4125-4133
    • (2001) J Neurosci , vol.21 , pp. 4125-4133
    • Dineley, K.T.1    Westerman, M.2    Bui, D.3    Bell, K.4    Ashe, K.H.5    Sweatt, J.D.6
  • 24
    • 80051988063 scopus 로고    scopus 로고
    • ConstitutivecAMPresponse element binding protein (CREB) activation by Alzheimer's disease presenilin-driven inositol trisphosphate receptor (InsP3R) Ca2+ signaling
    • Muller M, Cardenas C, Mei L, Cheung KH, Foskett JK. (2011). ConstitutivecAMPresponse element binding protein (CREB) activation by Alzheimer's disease presenilin-driven inositol trisphosphate receptor (InsP3R) Ca2+ signaling. Proc Natl Acad Sci U S A 108, 13293-13298
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 13293-13298
    • Muller, M.1    Cardenas, C.2    Mei, L.3    Cheung, K.H.4    Foskett, J.K.5
  • 26
    • 0029898252 scopus 로고    scopus 로고
    • Induction of CRE-mediated gene expression by stimuli that generate long-lasting LTP in area CA1 of the hippocampus
    • Impey S, Mark M, Villacres EC, Poser S, Chavkin C, Storm DR. (1996). Induction of CRE-mediated gene expression by stimuli that generate long-lasting LTP in area CA1 of the hippocampus. Neuron 16, 973-982
    • (1996) Neuron , vol.16 , pp. 973-982
    • Impey, S.1    Mark, M.2    Villacres, E.C.3    Poser, S.4    Chavkin, C.5    Storm, D.R.6
  • 27
    • 77953506502 scopus 로고    scopus 로고
    • Complex environment experience rescues impaired neurogenesis, enhances synaptic plasticity, and attenuates neuropathology in familial Alzheimer's disease-linked APPswe/PS1 Delta E9 mice
    • Hu YS, Xu P, Pigino G, Brady ST, Larson J, Lazarov O. (2010). Complex environment experience rescues impaired neurogenesis, enhances synaptic plasticity, and attenuates neuropathology in familial Alzheimer's disease-linked APPswe/PS1 Delta E9 mice. FASEB J 24, 1667-1681
    • (2010) FASEB J , vol.24 , pp. 1667-1681
    • Hu, Y.S.1    Xu, P.2    Pigino, G.3    Brady, S.T.4    Larson, J.5    Lazarov, O.6
  • 28
    • 84904333598 scopus 로고    scopus 로고
    • Reduced recognition memory is correlated with decrease in DNA methyltransferase1 and increase in histone deacetylase2 protein expression in old male mice
    • Singh P, Thakur MK. (2014). Reduced recognition memory is correlated with decrease in DNA methyltransferase1 and increase in histone deacetylase2 protein expression in old male mice. Biogerontology 15, 339-346
    • (2014) Biogerontology , vol.15 , pp. 339-346
    • Singh, P.1    Thakur, M.K.2
  • 29
    • 0034195204 scopus 로고    scopus 로고
    • Upregulation of cAMP response elementmediated gene expression during experience-dependent plasticity in adult neocortex
    • Barth AL, McKenna M, Glazewski S, Hill P, Impey S, Storm D, Fox K. (2000). Upregulation of cAMP response elementmediated gene expression during experience-dependent plasticity in adult neocortex. J Neurosci 20, 4206-4216
    • (2000) J Neurosci , vol.20 , pp. 4206-4216
    • Barth, A.L.1    McKenna, M.2    Glazewski, S.3    Hill, P.4    Impey, S.5    Storm, D.6    Fox, K.7
  • 30
    • 0037101970 scopus 로고    scopus 로고
    • Function and regulation ofCREB family transcription factors in the nervous system
    • Lonze BE, Ginty DD. (2002). Function and regulation ofCREB family transcription factors in the nervous system. Neuron 35, 605-623
    • (2002) Neuron , vol.35 , pp. 605-623
    • Lonze, B.E.1    Ginty, D.D.2
  • 32
    • 0028071507 scopus 로고
    • Deficient long-Term memory in mice with a targeted mutation of the cAMP-responsive element-binding protein
    • Bourtchuladze R, Frenguelli B, Blendy J, Cioffi D, Schutz G, Silva AJ. (1994). Deficient long-Term memory in mice with a targeted mutation of the cAMP-responsive element-binding protein. Cell 79, 59-68
    • (1994) Cell , vol.79 , pp. 59-68
    • Bourtchuladze, R.1    Frenguelli, B.2    Blendy, J.3    Cioffi, D.4    Schutz, G.5    Silva, A.J.6
  • 34
    • 0032195577 scopus 로고    scopus 로고
    • Stimulation of cAMP response element (CRE)-βmediated transcription during contextual learning
    • Impey S, Smith DM, Obrietan K, Donahue R, Wade C, Storm DR. (1998). Stimulation of cAMP response element (CRE)-βmediated transcription during contextual learning. Nat Neurosci 1, 595-601
    • (1998) Nat Neurosci , vol.1 , pp. 595-601
    • Impey, S.1    Smith, D.M.2    Obrietan, K.3    Donahue, R.4    Wade, C.5    Storm, D.R.6
  • 35
    • 0029133577 scopus 로고
    • A molecular switch for the consolidation of long-Term memory: CAMP-inducible gene expression
    • Alberini CM, Ghirardi M, Huang YY, Nguyen PV, Kandel ER. (1995). A molecular switch for the consolidation of long-Term memory: cAMP-inducible gene expression. Ann N Y Acad Sci 758, 261-286
    • (1995) Ann N y Acad Sci , vol.758 , pp. 261-286
    • Alberini, C.M.1    Ghirardi, M.2    Huang, Y.Y.3    Nguyen, P.V.4    Kandel, E.R.5
  • 36
    • 0033119839 scopus 로고    scopus 로고
    • Regulation of CBPmediated transcription by neuronal calcium signaling
    • Hu SC, Chrivia J, Ghosh A. (1999). Regulation of CBPmediated transcription by neuronal calcium signaling. Neuron 22, 799-808
    • (1999) Neuron , vol.22 , pp. 799-808
    • Hu, S.C.1    Chrivia, J.2    Ghosh, A.3
  • 37
    • 0028988020 scopus 로고
    • Involvement of the Ca(2+)-βdependent phosphatase calcineurin in gene transcription that is stimulated by cAMP through cAMP response elements
    • Schwaninger M, Blume R, Kruger M, Lux G, Oetjen E, Knepel W. (1995). Involvement of the Ca(2+)-βdependent phosphatase calcineurin in gene transcription that is stimulated by cAMP through cAMP response elements. J Biol Chem 270, 8860-8866
    • (1995) J Biol Chem , vol.270 , pp. 8860-8866
    • Schwaninger, M.1    Blume, R.2    Kruger, M.3    Lux, G.4    Oetjen, E.5    Knepel, W.6
  • 38
    • 0032055648 scopus 로고    scopus 로고
    • Identification of a signaling pathway involved in calcium regulation of BDNF expression
    • Shieh PB, Hu SC, Bobb K, Timmusk T, Ghosh A. (1998). Identification of a signaling pathway involved in calcium regulation of BDNF expression. Neuron 20, 727-740
    • (1998) Neuron , vol.20 , pp. 727-740
    • Shieh, P.B.1    Hu, S.C.2    Bobb, K.3    Timmusk, T.4    Ghosh, A.5
  • 39
    • 0029810469 scopus 로고    scopus 로고
    • Induction of bcl-2 expression by phosphorylated CREB proteins during B-cell activation and rescue from apoptosis
    • Wilson BE, Mochon E, Boxer LM. (1996). Induction of bcl-2 expression by phosphorylated CREB proteins during B-cell activation and rescue from apoptosis. Mol Cell Biol 16, 5546-5556
    • (1996) Mol Cell Biol , vol.16 , pp. 5546-5556
    • Wilson, B.E.1    Mochon, E.2    Boxer, L.M.3
  • 40
    • 84877951431 scopus 로고    scopus 로고
    • Molecular mechanisms of environmental enrichment: Impairments in Akt/GSK3 beta, neurotrophin-3 and CREB signaling
    • Hu YS, Long N, Pigino G, Brady ST, Lazarov O. (2013). Molecular mechanisms of environmental enrichment: impairments in Akt/GSK3 beta, neurotrophin-3 and CREB signaling. Plos One 8, e64460
    • (2013) Plos One , vol.8 , pp. e64460
    • Hu, Y.S.1    Long, N.2    Pigino, G.3    Brady, S.T.4    Lazarov, O.5
  • 41
    • 79551508983 scopus 로고    scopus 로고
    • Ablation ofCBPin forebrain principal neurons causes modest memory and transcriptional defects and a dramatic reduction of histone acetylation but does not affect cell viability
    • Valor LM, Pulopulos MM, Jimenez-Minchan M, Olivares R, Lutz B, Barco A. (2011). Ablation ofCBPin forebrain principal neurons causes modest memory and transcriptional defects and a dramatic reduction of histone acetylation but does not affect cell viability. J Neurosci 31, 1652-1663
    • (2011) J Neurosci , vol.31 , pp. 1652-1663
    • Valor, L.M.1    Pulopulos, M.M.2    Jimenez-Minchan, M.3    Olivares, R.4    Lutz, B.5    Barco, A.6
  • 43
    • 84921369579 scopus 로고    scopus 로고
    • Genome-wide functional analysis of CREB/long-Term memory-dependent transcription reveals distinct basal and memory gene expression programs
    • Lakhina V, Arey RN, Kaletsky R, Kauffman A, Stein G, Keyes W, Xu D, Murphy CT. (2015). Genome-wide functional analysis of CREB/long-Term memory-dependent transcription reveals distinct basal and memory gene expression programs. Neuron 85, 330-345
    • (2015) Neuron , vol.85 , pp. 330-345
    • Lakhina, V.1    Arey, R.N.2    Kaletsky, R.3    Kauffman, A.4    Stein, G.5    Keyes, W.6    Xu, D.7    Murphy, C.T.8
  • 47
    • 20044383377 scopus 로고    scopus 로고
    • Episodic-like memory deficits in the APPswe/PS1dE9 mouse model of Alzheimer's disease: Relationships to beta-Amyloid deposition and neurotransmitter abnormalities
    • Savonenko A, Xu GM, Melnikova T, Morton JL, Gonzales V, Wong MP, Price DL, Tang F, Markowska AL, Borchelt DR. (2005). Episodic-like memory deficits in the APPswe/PS1dE9 mouse model of Alzheimer's disease: relationships to beta-Amyloid deposition and neurotransmitter abnormalities. Neurobiol Dis 18, 602-617
    • (2005) Neurobiol Dis , vol.18 , pp. 602-617
    • Savonenko, A.1    Xu, G.M.2    Melnikova, T.3    Morton, J.L.4    Gonzales, V.5    Wong, M.P.6    Price, D.L.7    Tang, F.8    Markowska, A.L.9    Borchelt, D.R.10
  • 48
    • 84862782041 scopus 로고    scopus 로고
    • Early memory deficits precede plaque deposition in APPswe/PS1dE9 mice: Involvement of oxidative stress and cholinergic dysfunction
    • Zhang W, Bai M, Xi Y, Hao J, Liu L, Mao N, Su CJ, Miao JT, Li ZY. (2012). Early memory deficits precede plaque deposition in APPswe/PS1dE9 mice: Involvement of oxidative stress and cholinergic dysfunction. Free Radic Biol Med 52, 1443-1452
    • (2012) Free Radic Biol Med , vol.52 , pp. 1443-1452
    • Zhang, W.1    Bai, M.2    Xi, Y.3    Hao, J.4    Liu, L.5    Mao, N.6    Su, C.J.7    Miao, J.T.8    Li, Z.Y.9
  • 49
    • 84952638033 scopus 로고    scopus 로고
    • CREB expression mediates amyloid beta-induced basal BDNF downregulation
    • Rosa E, Fahnestock M. (2015). CREB expression mediates amyloid beta-induced basal BDNF downregulation. Neurobiol Aging 36, 2406-2413
    • (2015) Neurobiol Aging , vol.36 , pp. 2406-2413
    • Rosa, E.1    Fahnestock, M.2
  • 50
    • 0036792096 scopus 로고    scopus 로고
    • Amyloid beta-peptide inhibition of the PKA/CREB pathway and long-Term potentiation: Reversibility by drugs that enhance cAMP signaling
    • Vitolo OV, Sant'Angelo A, Costanzo V, Battaglia F, Arancio O, Shelanski M. (2002). Amyloid beta-peptide inhibition of the PKA/CREB pathway and long-Term potentiation: Reversibility by drugs that enhance cAMP signaling. Proc Natl Acad Sci U S A 99, 13217-13221
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 13217-13221
    • Vitolo, O.V.1    Sant'Angelo, A.2    Costanzo, V.3    Battaglia, F.4    Arancio, O.5    Shelanski, M.6
  • 51
    • 0035907325 scopus 로고    scopus 로고
    • Beta-Amyloid-(1-42) impairs activity-dependent cAMP-response element-binding protein signaling in neurons at concentrations in which cell survival is not compromised
    • Tong LQ, Thornton PL, Balazs R, Cotman CW. (2001). beta-Amyloid-(1-42) impairs activity-dependent cAMP-response element-binding protein signaling in neurons at concentrations in which cell survival is not compromised. J Biol Chem 276, 17301-17306
    • (2001) J Biol Chem , vol.276 , pp. 17301-17306
    • Tong, L.Q.1    Thornton, P.L.2    Balazs, R.3    Cotman, C.W.4
  • 52
    • 0037111837 scopus 로고    scopus 로고
    • Evidence that synaptically released beta-Amyloid accumulates as extracellular deposits in the hippocampus of transgenic mice
    • Lazarov O, Lee M, Peterson DA, Sisodia SS. (2002). Evidence that synaptically released beta-Amyloid accumulates as extracellular deposits in the hippocampus of transgenic mice. J Neurosci 22, 9785-9793
    • (2002) J Neurosci , vol.22 , pp. 9785-9793
    • Lazarov, O.1    Lee, M.2    Peterson, D.A.3    Sisodia, S.S.4
  • 55
    • 83155180349 scopus 로고    scopus 로고
    • Huperzine A alleviates synaptic deficits and modulates amyloidogenic and nonamyloidogenic pathways in APPswe/PS1dE9 transgenic mice
    • Wang Y, Tang XC, Zhang HY. (2012). Huperzine A alleviates synaptic deficits and modulates amyloidogenic and nonamyloidogenic pathways in APPswe/PS1dE9 transgenic mice. J Neurosci Res 90, 508-517
    • (2012) J Neurosci Res , vol.90 , pp. 508-517
    • Wang, Y.1    Tang, X.C.2    Zhang, H.Y.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.