Plug flow versus stirred tank reactor flow characteristics in two-compartment scale-down bioreactor: Setup-specific influence on the metabolic phenotype and bioprocess performance of Corynebacterium glutamicum

Engineering in Life Sciences

Volumn 16, Issue 7, 2016, Pages 610-619

  Limberg, Michael H ^a   Pooth, Viola ^a   Wiechert, Wolfgang ^a   Oldiges, Marco ^a  

^a FORSCHUNGSZENTRUM JÜLICH   (Germany)

Author keywords

Bioprocess development; Bioreactor inhomogeneities; Corynebacterium glutamicum; Scale up and down; Two compartment bioreactor

Indexed keywords

AMINO ACIDS; BIOCONVERSION; BIOREACTORS; CULTIVATION; INDUSTRIAL RESEARCH; METABOLISM; TANKS (CONTAINERS);

BIOPROCESS DEVELOPMENT; BIOREACTOR CONFIGURATIONS; CORYNEBACTERIUM GLUTAMICUM; CULTIVATION CONDITIONS; FLOW CHARAC-TERISTICS; INHOMOGENEITIES; SCALE-UP; STIRRED TANK REACTORS;

RESIDENCE TIME DISTRIBUTION;

GLUTAMIC ACID; LACTIC ACID; LYSINE; OXYGEN;

BACTERIUM; BIOACTIVITY; BIOMASS; BIOREACTOR; CULTIVATION; GROWTH RATE; INHOMOGENEITY; METABOLISM; PERFORMANCE ASSESSMENT; PHENOTYPE; RESIDENCE TIME; SCALE EFFECT;

ARTICLE; BACTERIAL GROWTH; BACTERIAL METABOLISM; BACTERIUM CULTURE; BATCH PROCESS; BIOMASS PRODUCTION; BIOPROCESS; BIOREACTOR; COMPARATIVE STUDY; CONTROLLED STUDY; CORYNEBACTERIUM GLUTAMICUM; GROWTH RATE; HYDRODYNAMICS; MICROBIAL BIOMASS; NONHUMAN; PERISTALTIC PUMP; PHENOTYPE; PLUG FLOW REACTOR; STIRRED REACTOR; TWO COMPONENT SCALE DOWN BIOREACTOR;

CORYNEBACTERIUM GLUTAMICUM;

EID: 84969961842     PISSN: 16180240     EISSN: 16182863     Source Type: Journal    
DOI: 10.1002/elsc.201500142     Document Type: Article

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