Response of Corynebacterium glutamicum exposed to oscillating cultivation conditions in a two- and a novel three-compartment scale-down bioreactor

Biotechnology and Bioengineering

Volumn 112, Issue 6, 2015, Pages 1220-1231

  Lemoine, Anja ^a   Maya Martnez Iturralde, Nina ^a   Spann, Robert ^a   Neubauer, Peter ^a   Junne, Stefan ^a  

^a TECHNISCHE UNIVERSITÄT BERLIN   (Germany)

Author keywords

Compartment reactor; Corynebacterium; Heterogeneity; Lysine; Oscillation; Scale down

Indexed keywords

AMINO ACIDS; BIOREACTORS; CELL DEATH; CELLS; CYTOLOGY; OPTIMIZATION; OXYGEN; OXYGEN SUPPLY; POLARIZATION;

COMPARTMENT REACTOR; CORYNEBACTERIUM; HETEROGENEITY; LYSINE; OSCILLATION; SCALE DOWN;

CULTIVATION;

GLUTAMIC ACID; GLUTAMINE; GLYCINE; LACTATE DEHYDROGENASE; LACTIC ACID; PYRUVIC ACID; SUCCINIC ACID; THREONINE; AMINO ACID; CULTURE MEDIUM; OXYGEN;

ARTICLE; BACTERIAL GROWTH; BIOREACTOR; CELL DEATH; CELL POLARITY; CELL VIABILITY; CITRIC ACID CYCLE; CONCENTRATION (PARAMETERS); CORYNEBACTERIUM GLUTAMICUM; FED BATCH REACTOR; FLOW CYTOMETRY; HYDROLYSIS; MEAN RESIDENCE TIME; MEMBRANE POTENTIAL; MICROBIAL BIOMASS; NONHUMAN; OPTICAL DENSITY; OSCILLATION; OXYGEN SUPPLY; POINT MUTATION; PROCESS OPTIMIZATION; PROTEIN EXPRESSION; STIRRED REACTOR; THREE COMPARTMENT REACTOR; TWO COMPARTMENT REACTOR; CARBOHYDRATE METABOLISM; CHEMISTRY; CULTURE MEDIUM; GROWTH, DEVELOPMENT AND AGING; METABOLISM; MICROBIOLOGY;

CORYNEBACTERIUM; CORYNEBACTERIUM GLUTAMICUM;

AMINO ACIDS; BIOREACTORS; CARBOHYDRATE METABOLISM; CORYNEBACTERIUM GLUTAMICUM; CULTURE MEDIA; OXYGEN;

EID: 84928423375     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.25543     Document Type: Article

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