메뉴 건너뛰기




Volumn 12, Issue 7, 2016, Pages 546-551

NSUN3 methylase initiates 5-formylcytidine biogenesis in human mitochondrial tRNA Met

Author keywords

[No Author keywords available]

Indexed keywords

5 FORMYLCYTIDINE; CYTIDINE DERIVATIVE; METHIONINE; METHYLTRANSFERASE; MITOCHONDRIAL PROTEIN; NSUN3 METHYLASE; S ADENOSYLMETHIONINE; TRANSFER RNA; UNCLASSIFIED DRUG; 5-FORMYLCYTIDINE; CYTIDINE; METHIONINE TRANSFER RNA; RNA; RNA, MITOCHONDRIAL;

EID: 84969884872     PISSN: 15524450     EISSN: 15524469     Source Type: Journal    
DOI: 10.1038/nchembio.2099     Document Type: Article
Times cited : (170)

References (56)
  • 1
    • 84875692043 scopus 로고    scopus 로고
    • MODOMICS: A database of RNA modification pathways-2013 update
    • Machnicka, M.A. et al. MODOMICS: a database of RNA modification pathways-2013 update. Nucleic Acids Res. 41, D262-D267 (2013).
    • (2013) Nucleic Acids Res. , vol.41 , pp. D262-D267
    • MacHnicka, M.A.1
  • 2
    • 0002495140 scopus 로고
    • (eds. Soll, D., RajBhandary, U.L. (American Society for Microbiology
    • Bjork, G. in tRNA: Structure, Biosynthesis, and Function (eds. Soll, D., RajBhandary, U.L.) 165-205 (American Society for Microbiology, 1995).
    • (1995) TRNA: Structure, Biosyn Thesis and Function , pp. 165-205
    • Bjork, G.1
  • 4
    • 23844558266 scopus 로고    scopus 로고
    • A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: A dawn for evolutionary medicine
    • Wallace, D.C. A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: a dawn for evolutionary medicine. Annu. Rev. Genet. 39, 359-407 (2005).
    • (2005) Annu. Rev. Genet. , vol.39 , pp. 359-407
    • Wallace, D.C.1
  • 5
    • 80755169463 scopus 로고    scopus 로고
    • Human mitochondrial tRNAs: Biogenesis, function, structural aspects, and diseases
    • Suzuki, T., Nagao, A., Suzuki, T. Human mitochondrial tRNAs: biogenesis, function, structural aspects, and diseases. Annu. Rev. Genet. 45, 299-329 (2011).
    • (2011) Annu. Rev. Genet. , vol.45 , pp. 299-329
    • Suzuki, T.1    Nagao, A.2    Suzuki, T.3
  • 6
    • 84905820302 scopus 로고    scopus 로고
    • Making proteins in the powerhouse
    • Hällberg, B.M., Larsson, N.G. Making proteins in the powerhouse. Cell Metab. 20, 226-240 (2014).
    • (2014) Cell Metab. , vol.20 , pp. 226-240
    • Hällberg, B.M.1    Larsson, N.G.2
  • 7
    • 84903151976 scopus 로고    scopus 로고
    • A complete landscape of post-transcriptional modifications in mammalian mitochondrial tRNAs
    • Suzuki, T., Suzuki, T. A complete landscape of post-transcriptional modifications in mammalian mitochondrial tRNAs. Nucleic Acids Res. 42, 7346-7357 (2014).
    • (2014) Nucleic Acids Res. , vol.42 , pp. 7346-7357
    • Suzuki, T.1    Suzuki, T.2
  • 8
    • 0037011177 scopus 로고    scopus 로고
    • Taurine as a constituent of mitochondrial tRNAs: New insights into the functions of taurine and human mitochondrial diseases
    • Suzuki, T., Suzuki, T., Wada, T., Saigo, K., Watanabe, K. Taurine as a constituent of mitochondrial tRNAs: new insights into the functions of taurine and human mitochondrial diseases. EMBO J. 21, 6581-6589 (2002).
    • (2002) EMBO J. , vol.21 , pp. 6581-6589
    • Suzuki, T.1    Suzuki, T.2    Wada, T.3    Saigo, K.4    Watanabe, K.5
  • 9
    • 6344221310 scopus 로고    scopus 로고
    • Codon-specific translational defect caused by a wobble modification deficiency in mutant tRNA from a human mitochondrial disease
    • Kirino, Y. et al. Codon-specific translational defect caused by a wobble modification deficiency in mutant tRNA from a human mitochondrial disease. Proc. Natl. Acad. Sci. USA 101, 15070-15075 (2004).
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 15070-15075
    • Kirino, Y.1
  • 10
    • 48349090037 scopus 로고    scopus 로고
    • Modified uridines with C5-methylene substituents at the first position of the tRNA anticodon stabilize U•G wobble pairing during decoding
    • Kurata, S. et al. Modified uridines with C5-methylene substituents at the first position of the tRNA anticodon stabilize U•G wobble pairing during decoding. J. Biol. Chem. 283, 18801-18811 (2008).
    • (2008) J. Biol. Chem. , vol.283 , pp. 18801-18811
    • Kurata, S.1
  • 11
    • 0028226958 scopus 로고
    • A novel modified nucleoside found at the first position of the anticodon of methionine tRNA from bovine liver mitochondria
    • Moriya, J. et al. A novel modified nucleoside found at the first position of the anticodon of methionine tRNA from bovine liver mitochondria. Biochemistry 33, 2234-2239 (1994).
    • (1994) Biochemistry , vol.33 , pp. 2234-2239
    • Moriya, J.1
  • 12
    • 63249103619 scopus 로고    scopus 로고
    • Unconventional decoding of the AUA codon as methionine by mitochondrial tRNAMet with the anticodon f5CAU as revealed with a mitochondrial in vitro translation system
    • Takemoto, C. et al. Unconventional decoding of the AUA codon as methionine by mitochondrial tRNAMet with the anticodon f5CAU as revealed with a mitochondrial in vitro translation system. Nucleic Acids Res. 37, 1616-1627 (2009).
    • (2009) Nucleic Acids Res. , vol.37 , pp. 1616-1627
    • Takemoto, C.1
  • 14
    • 84867597592 scopus 로고    scopus 로고
    • Human mitochondrial diseases caused by lack of taurine modification in mitochondrial tRNAs Wiley Interdiscip
    • Suzuki, T., Nagao, A., Suzuki, T. Human mitochondrial diseases caused by lack of taurine modification in mitochondrial tRNAs. Wiley Interdiscip. Rev. RNA 2, 376-386 (2011).
    • (2011) Rev. RNA , vol.2 , pp. 376-386
    • Suzuki, T.1    Nagao, A.2    Suzuki, T.3
  • 15
    • 0034635519 scopus 로고    scopus 로고
    • Modification defect at anticodon wobble nucleotide of mitochondrial tRNAsLeu(UUR) with pathogenic mutations of mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes
    • Yasukawa, T., Suzuki, T., Ueda, T., Ohta, S., Watanabe, K. Modification defect at anticodon wobble nucleotide of mitochondrial tRNAsLeu(UUR) with pathogenic mutations of mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes. J. Biol. Chem. 275, 4251-4257 (2000).
    • (2000) J. Biol. Chem. , vol.275 , pp. 4251-4257
    • Yasukawa, T.1    Suzuki, T.2    Ueda, T.3    Ohta, S.4    Watanabe, K.5
  • 16
    • 0033968067 scopus 로고    scopus 로고
    • Defect in modification at the anticodon wobble nucleotide of mitochondrial tRNALys with the MERRF encephalomyopathy pathogenic mutation
    • Yasukawa, T. et al. Defect in modification at the anticodon wobble nucleotide of mitochondrial tRNALys with the MERRF encephalomyopathy pathogenic mutation. FEBS Lett. 467, 175-178 (2000).
    • (2000) FEBS Lett. , vol.467 , pp. 175-178
    • Yasukawa, T.1
  • 17
    • 18844430007 scopus 로고    scopus 로고
    • Specific correlation between the wobble modification deficiency in mutant tRNAs and the clinical features of a human mitochondrial disease
    • Kirino, Y., Goto, Y., Campos, Y., Arenas, J., Suzuki, T. Specific correlation between the wobble modification deficiency in mutant tRNAs and the clinical features of a human mitochondrial disease. Proc. Natl. Acad. Sci. USA 102, 7127-7132 (2005).
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 7127-7132
    • Kirino, Y.1    Goto, Y.2    Campos, Y.3    Arenas, J.4    Suzuki, T.5
  • 18
    • 21144455795 scopus 로고    scopus 로고
    • Wobble modification deficiency in mutant tRNAs in patients with mitochondrial diseases
    • Yasukawa, T. et al. Wobble modification deficiency in mutant tRNAs in patients with mitochondrial diseases. FEBS Lett. 579, 2948-2952 (2005).
    • (2005) FEBS Lett. , vol.579 , pp. 2948-2952
    • Yasukawa, T.1
  • 19
    • 12544259245 scopus 로고    scopus 로고
    • Mitochondria-specific RNA-modifying enzymes responsible for the biosynthesis of the wobble base in mitochondrial tRNAs. Implications for the molecular pathogenesis of human mitochondrial diseases
    • Umeda, N. et al. Mitochondria-specific RNA-modifying enzymes responsible for the biosynthesis of the wobble base in mitochondrial tRNAs. Implications for the molecular pathogenesis of human mitochondrial diseases. J. Biol. Chem. 280, 1613-1624 (2005).
    • (2005) J. Biol. Chem. , vol.280 , pp. 1613-1624
    • Umeda, N.1
  • 20
    • 0032510952 scopus 로고    scopus 로고
    • Mammalian mitochondrial methionyl-tRNA transformylase from bovine liver. Purification, characterization, and gene structure
    • Takeuchi, N. et al. Mammalian mitochondrial methionyl-tRNA transformylase from bovine liver. Purification, characterization, and gene structure. J. Biol. Chem. 273, 15085-15090 (1998).
    • (1998) J. Biol. Chem. , vol.273 , pp. 15085-15090
    • Takeuchi, N.1
  • 21
    • 84906489691 scopus 로고    scopus 로고
    • Mitochondrial one-carbon metabolism and neural tube defects
    • Momb, J., Appling, D.R. Mitochondrial one-carbon metabolism and neural tube defects. Birth Defects Res. A Clin. Mol. Teratol. 100, 576-583 (2014).
    • (2014) Birth Defects Res. A Clin. Mol. Teratol. , vol.100 , pp. 576-583
    • Momb, J.1    Appling, D.R.2
  • 22
    • 84892763878 scopus 로고    scopus 로고
    • Reversing DNA methylation: Mechanisms, genomics, and biological functions
    • Wu, H., Zhang, Y. Reversing DNA methylation: mechanisms, genomics, and biological functions. Cell 156, 45-68 (2014).
    • (2014) Cell , vol.156 , pp. 45-68
    • Wu, H.1    Zhang, Y.2
  • 23
    • 34047143747 scopus 로고    scopus 로고
    • Automated parallel isolation of multiple species of non-coding RNAs by the reciprocal circulating chromatography method
    • Miyauchi, K., Ohara, T., Suzuki, T. Automated parallel isolation of multiple species of non-coding RNAs by the reciprocal circulating chromatography method. Nucleic Acids Res. 35, e24 (2007).
    • (2007) Nucleic Acids Res. , vol.35 , pp. e24
    • Miyauchi, K.1    Ohara, T.2    Suzuki, T.3
  • 24
    • 84874956967 scopus 로고    scopus 로고
    • Proteomic mapping of mitochondria in living cells via spatially restricted enzymatic tagging
    • Rhee, H.W. et al. Proteomic mapping of mitochondria in living cells via spatially restricted enzymatic tagging. Science 339, 1328-1331 (2013).
    • (2013) Science , vol.339 , pp. 1328-1331
    • Rhee, H.W.1
  • 25
    • 0026457218 scopus 로고
    • Nonviability of cells with oxidative defects in galactose medium: A screening test for affected patient fibroblasts
    • Robinson, B.H., Petrova-Benedict, R., Buncic, J.R., Wallace, D.C. Nonviability of cells with oxidative defects in galactose medium: a screening test for affected patient fibroblasts. Biochem. Med. Metab. Biol. 48, 122-126 (1992).
    • (1992) Biochem. Med. Metab. Biol. , vol.48 , pp. 122-126
    • Robinson, B.H.1    Petrova-Benedict, R.2    Buncic, J.R.3    Wallace, D.C.4
  • 26
    • 84896385812 scopus 로고    scopus 로고
    • MtDNA variation and analysis using MITOMAP and MITOMASTER
    • Lott, M.T. et al. mtDNA variation and analysis using MITOMAP and MITOMASTER. Curr. Protoc. Bioinformatics 1, 1.23.1-1.23.26 (2013).
    • (2013) Curr. Protoc. Bioinformatics , vol.1 , pp. 1231-12326
    • Lott, M.T.1
  • 27
    • 84937002114 scopus 로고    scopus 로고
    • RNA N6-methyladenosine methylation in post-transcriptional gene expression regulation
    • Yue, Y., Liu, J., He, C. RNA N6-methyladenosine methylation in post-transcriptional gene expression regulation. Genes Dev. 29, 1343-1355 (2015).
    • (2015) Genes Dev. , vol.29 , pp. 1343-1355
    • Yue, Y.1    Liu, J.2    He, C.3
  • 28
    • 80052495940 scopus 로고    scopus 로고
    • Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA
    • He, Y.F. et al. Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA. Science 333, 1303-1307 (2011).
    • (2011) Science , vol.333 , pp. 1303-1307
    • He, Y.F.1
  • 29
    • 80052461558 scopus 로고    scopus 로고
    • Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine
    • Ito, S. et al. Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine. Science 333, 1300-1303 (2011).
    • (2011) Science , vol.333 , pp. 1300-1303
    • Ito, S.1
  • 30
    • 0029988415 scopus 로고    scopus 로고
    • 2?-O-methyl-5-formylcytidine (f5Cm) a new modified nucleotide at the 'wobble' of two cytoplasmic tRNAs Leu (NAA) from bovine liver
    • Païs de Barros, J.P. et al. 2?-O-methyl-5-formylcytidine (f5Cm), a new modified nucleotide at the 'wobble' of two cytoplasmic tRNAs Leu (NAA) from bovine liver. Nucleic Acids Res. 24, 1489-1496 (1996).
    • (1996) Nucleic Acids Res. , vol.24 , pp. 1489-1496
    • Païs De Barros, J.P.1
  • 31
    • 84924918523 scopus 로고    scopus 로고
    • Formation and abundance of 5-hydroxymethylcytosine in RNA
    • Huber, S.M. et al. Formation and abundance of 5-hydroxymethylcytosine in RNA. ChemBioChem 16, 752-755 (2015).
    • (2015) ChemBioChem , vol.16 , pp. 752-755
    • Huber, S.M.1
  • 32
    • 0019423856 scopus 로고
    • Sequence and organization of the human mitochondrial genome
    • Anderson, S. et al. Sequence and organization of the human mitochondrial genome. Nature 290, 457-465 (1981).
    • (1981) Nature , vol.290 , pp. 457-465
    • Anderson, S.1
  • 33
    • 84890231951 scopus 로고    scopus 로고
    • Ribosome profiling reveals features of normal and disease-associated mitochondrial translation
    • Rooijers, K., Loayza-Puch, F., Nijtmans, L.G., Agami, R. Ribosome profiling reveals features of normal and disease-associated mitochondrial translation. Nat. Commun. 4, 2886 (2013).
    • (2013) Nat. Commun. , vol.4 , pp. 2886
    • Rooijers, K.1    Loayza-Puch, F.2    Nijtmans, L.G.3    Agami, R.4
  • 34
    • 3343015683 scopus 로고    scopus 로고
    • Characterization of the human mitochondrial methionyl-tRNA synthetase
    • Spencer, A.C., Heck, A., Takeuchi, N., Watanabe, K., Spremulli, L.L. Characterization of the human mitochondrial methionyl-tRNA synthetase. Biochemistry 43, 9743-9754 (2004).
    • (2004) Biochemistry , vol.43 , pp. 9743-9754
    • Spencer, A.C.1    Heck, A.2    Takeuchi, N.3    Watanabe, K.4    Spremulli, L.L.5
  • 35
    • 84880336220 scopus 로고    scopus 로고
    • Expression of NOL1/NOP2/Sun domain (Nsun) RNA methyltransferase family genes in early mouse embryogenesis
    • Chi, L., Delgado-Olguín, P. Expression of NOL1/NOP2/Sun domain (Nsun) RNA methyltransferase family genes in early mouse embryogenesis. Gene Expr. Patterns 13, 319-327 (2013).
    • (2013) Gene Expr. Patterns , vol.13 , pp. 319-327
    • Chi, L.1    Delgado-Olguín, P.2
  • 36
    • 84885993080 scopus 로고    scopus 로고
    • Yeast Nop2 and Rcm1 methylate C2870 and C2278 of the 25S rRNA, respectively
    • Sharma, S., Yang, J., Watzinger, P., Kötter, P., Entian, K.D. Yeast Nop2 and Rcm1 methylate C2870 and C2278 of the 25S rRNA, respectively. Nucleic Acids Res. 41, 9062-9076 (2013).
    • (2013) Nucleic Acids Res. , vol.41 , pp. 9062-9076
    • Sharma, S.1    Yang, J.2    Watzinger, P.3    Kötter, P.4    Entian, K.D.5
  • 37
    • 33845599493 scopus 로고    scopus 로고
    • Identification of human tRNA:m5C methyltransferase catalysing intron-dependent m5C formation in the first position of the anticodon of the pre-tRNALeu(CAA)
    • Brzezicha, B. et al. Identification of human tRNA:m5C methyltransferase catalysing intron-dependent m5C formation in the first position of the anticodon of the pre-tRNALeu(CAA). Nucleic Acids Res. 34, 6034-6043 (2006).
    • (2006) Nucleic Acids Res. , vol.34 , pp. 6034-6043
    • Brzezicha, B.1
  • 38
    • 84880791572 scopus 로고    scopus 로고
    • NSun2-mediated cytosine-5 methylation of vault noncoding RNA determines its processing into regulatory small RNAs
    • Hussain, S. et al. NSun2-mediated cytosine-5 methylation of vault noncoding RNA determines its processing into regulatory small RNAs. Cell Rep. 4, 255-261 (2013).
    • (2013) Cell Rep. , vol.4 , pp. 255-261
    • Hussain, S.1
  • 39
    • 84860751168 scopus 로고    scopus 로고
    • Widespread occurrence of 5-methylcytosine in human coding and non-coding RNA
    • Squires, J.E. et al. Widespread occurrence of 5-methylcytosine in human coding and non-coding RNA. Nucleic Acids Res. 40, 5023-5033 (2012).
    • (2012) Nucleic Acids Res. , vol.40 , pp. 5023-5033
    • Squires, J.E.1
  • 40
    • 84939839793 scopus 로고    scopus 로고
    • NSUN6 is a human RNA methyltransferase that catalyzes formation of m5C72 in specific tRNAs
    • Haag, S. et al. NSUN6 is a human RNA methyltransferase that catalyzes formation of m5C72 in specific tRNAs. RNA 21, 1532-1543 (2015).
    • (2015) RNA , vol.21 , pp. 1532-1543
    • Haag, S.1
  • 41
    • 84901741929 scopus 로고    scopus 로고
    • NSUN4 is a dual function mitochondrial protein required for both methylation of 12S rRNA and coordination of mitoribosomal assembly
    • Metodiev, M.D. et al. NSUN4 is a dual function mitochondrial protein required for both methylation of 12S rRNA and coordination of mitoribosomal assembly. PLoS Genet. 10, e1004110 (2014).
    • (2014) PLoS Genet. , vol.10 , pp. e1004110
    • Metodiev, M.D.1
  • 42
    • 84866559286 scopus 로고    scopus 로고
    • Structure of the human MTERF4-NSUN4 protein complex that regulates mitochondrial ribosome biogenesis
    • Spåhr, H., Habermann, B., Gustafsson, C.M., Larsson, N.G., Hallberg, B.M. Structure of the human MTERF4-NSUN4 protein complex that regulates mitochondrial ribosome biogenesis. Proc. Natl. Acad. Sci. USA 109, 15253-15258 (2012).
    • (2012) Proc. Natl. Acad. Sci. USA , vol.109 , pp. 15253-15258
    • Spåhr, H.1    Habermann, B.2    Gustafsson, C.M.3    Larsson, N.G.4    Hallberg, B.M.5
  • 43
    • 34547447763 scopus 로고    scopus 로고
    • Sperm motility defects and infertility in male mice with a mutation in Nsun7, a member of the Sun domain-containing family of putative RNA methyltransferases
    • Harris, T., Marquez, B., Suarez, S., Schimenti, J. Sperm motility defects and infertility in male mice with a mutation in Nsun7, a member of the Sun domain-containing family of putative RNA methyltransferases. Biol. Reprod. 77, 376-382 (2007).
    • (2007) Biol. Reprod. , vol.77 , pp. 376-382
    • Harris, T.1    Marquez, B.2    Suarez, S.3    Schimenti, J.4
  • 44
    • 0033289563 scopus 로고    scopus 로고
    • Nucleotide sequences of animal mitochondrial tRNAsMet possibly recognizing both AUG and AUA codons
    • Takemoto, C., Ueda, T., Miura, K., Watanabe, K. Nucleotide sequences of animal mitochondrial tRNAsMet possibly recognizing both AUG and AUA codons. Nucleic Acids Symp. Ser. 42, 77-78 (1999).
    • (1999) Nucleic Acids Symp. Ser. , vol.42 , pp. 77-78
    • Takemoto, C.1    Ueda, T.2    Miura, K.3    Watanabe, K.4
  • 45
    • 0028144722 scopus 로고
    • Primary and higher order structures of nematode (Ascaris suum) mitochondrial tRNAs lacking either the T or D stem
    • Watanabe, Y. et al. Primary and higher order structures of nematode (Ascaris suum) mitochondrial tRNAs lacking either the T or D stem. J. Biol. Chem. 269, 22902-22906 (1994).
    • (1994) J. Biol. Chem. , vol.269 , pp. 22902-22906
    • Watanabe, Y.1
  • 46
    • 80054813903 scopus 로고    scopus 로고
    • The tRNAMet 4435A>G mutation in the mitochondrial haplogroup G2a1 is responsible for maternally inherited hypertension in a Chinese pedigree
    • Lu, Z. et al. The tRNAMet 4435A>G mutation in the mitochondrial haplogroup G2a1 is responsible for maternally inherited hypertension in a Chinese pedigree. Eur. J. Hum. Genet. 19, 1181-1186 (2011).
    • (2011) Eur. J. Hum. Genet. , vol.19 , pp. 1181-1186
    • Lu, Z.1
  • 47
    • 33644868369 scopus 로고    scopus 로고
    • The novel A4435G mutation in the mitochondrial tRNAMet may modulate the phenotypic expression of the LHON-associated ND4 G11778A mutation
    • Qu, J. et al. The novel A4435G mutation in the mitochondrial tRNAMet may modulate the phenotypic expression of the LHON-associated ND4 G11778A mutation. Invest. Ophthalmol. Vis. Sci. 47, 475-483 (2006).
    • (2006) Invest. Ophthalmol. Vis. Sci. , vol.47 , pp. 475-483
    • Qu, J.1
  • 48
    • 84878116632 scopus 로고    scopus 로고
    • Transition to next generation analysis of the whole mitochondrial genome: A summary of molecular defects
    • Tang, S. et al. Transition to next generation analysis of the whole mitochondrial genome: a summary of molecular defects. Hum. Mutat. 34, 882-893 (2013).
    • (2013) Hum. Mutat. , vol.34 , pp. 882-893
    • Tang, S.1
  • 50
    • 84873729095 scopus 로고    scopus 로고
    • Multiplex genome engineering using CRISPR/Cas systems
    • Cong, L. et al. Multiplex genome engineering using CRISPR/Cas systems. Science 339, 819-823 (2013).
    • (2013) Science , vol.339 , pp. 819-823
    • Cong, L.1
  • 51
    • 84877341702 scopus 로고    scopus 로고
    • Top-down interrogation of chemically modified oligonucleotides by negative electron transfer and collision induced dissociation
    • Gao, Y., Yang, J., Cancilla, M.T., Meng, F., McLuckey, S.A. Top-down interrogation of chemically modified oligonucleotides by negative electron transfer and collision induced dissociation. Anal. Chem. 85, 4713-4720 (2013).
    • (2013) Anal. Chem. , vol.85 , pp. 4713-4720
    • Gao, Y.1    Yang, J.2    Cancilla, M.T.3    Meng, F.4    McLuckey, S.A.5
  • 52
    • 84885037202 scopus 로고    scopus 로고
    • Structural and functional analyses of DNA-sensing and immune activation by human cGAS
    • Kato, K. et al. Structural and functional analyses of DNA-sensing and immune activation by human cGAS. PLoS One 8, e76983 (2013).
    • (2013) PLoS One , vol.8 , pp. e76983
    • Kato, K.1
  • 53
    • 33750295885 scopus 로고    scopus 로고
    • Transfection of mammalian cells using linear polyethylenimine is a simple and effective means of producing recombinant adeno-associated virus vectors
    • Reed, S.E., Staley, E.M., Mayginnes, J.P., Pintel, D.J., Tullis, G.E. Transfection of mammalian cells using linear polyethylenimine is a simple and effective means of producing recombinant adeno-associated virus vectors. J. Virol. Methods 138, 85-98 (2006).
    • (2006) J. Virol. Methods , vol.138 , pp. 85-98
    • Reed, S.E.1    Staley, E.M.2    Mayginnes, J.P.3    Pintel, D.J.4    Tullis, G.E.5
  • 54
    • 84940542925 scopus 로고    scopus 로고
    • Single methylation of 23S rRNA triggers late steps of 50S ribosomal subunit assembly
    • Arai, T. et al. Single methylation of 23S rRNA triggers late steps of 50S ribosomal subunit assembly. Proc. Natl. Acad. Sci. USA 112, E4707-E4716 (2015).
    • (2015) Proc. Natl. Acad. Sci. USA , vol.112 , pp. E4707-E4716
    • Arai, T.1
  • 55
    • 0023953676 scopus 로고
    • Biochemical and physical characterization of an unmodified yeast phenylalanine transfer RNA transcribed in vitro
    • Sampson, J.R., Uhlenbeck, O.C. Biochemical and physical characterization of an unmodified yeast phenylalanine transfer RNA transcribed in vitro. Proc. Natl. Acad. Sci. USA 85, 1033-1037 (1988).
    • (1988) Proc. Natl. Acad. Sci. USA , vol.85 , pp. 1033-1037
    • Sampson, J.R.1    Uhlenbeck, O.C.2
  • 56
    • 38449085292 scopus 로고    scopus 로고
    • (ed. The C. elegans Research Community) 11 February
    • Stiernagle, T. in WormBook (ed. The C. elegans Research Community) doi:10.1895/wormbook.1.101.1 (11 February 2006).
    • (2006) WormBook
    • Stiernagle, T.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.