The tRNA Met 4435A>G mutation in the mitochondrial haplogroup G2a1 is responsible for maternally inherited hypertension in a Chinese pedigree

European Journal of Human Genetics

Volumn 19, Issue 11, 2011, Pages 1181-1186

  Lu, Zhongqiu ^a,b   Chen, Hong ^b   Meng, Yanzi ^b   Wang, Yan ^b   Xue, Ling ^b   Zhi, Shaoce ^a   Qiu, Qiaomeng ^a   Yang, Li ^c   Mo, Jun Qin ^c   Guan, Min Xin ^b,c,d  

^a THE FIRST AFFILIATED HOSPITAL OF WENZHOU MEDICAL UNIVERSITY   (China)

^b WENZHOU MEDICAL UNIVERSITY   (China)

^c CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^d ZHEJIANG UNIVERSITY   (China)

Author keywords

hypertension; maternal inheritance; mitochondria; risk factor; tRNA metabolism

Indexed keywords

MITOCHONDRIAL DNA; TRANSFER RNA; METHIONINE TRANSFER RNA;

ADULT; ARTICLE; ASIAN; CHINESE; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; MATERNAL HYPERTENSION; POINT MUTATION; PRIORITY JOURNAL; AGED; CHEMISTRY; CHINA; GENETIC PREDISPOSITION; GENETICS; HYPERTENSION; MIDDLE AGED; MOLECULAR GENETICS; MUTATION; NUCLEOTIDE SEQUENCE; PEDIGREE;

ADULT; AGED; ASIAN CONTINENTAL ANCESTRY GROUP; BASE SEQUENCE; CHINA; DNA, MITOCHONDRIAL; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; HYPERTENSION; MALE; MIDDLE AGED; MOLECULAR SEQUENCE DATA; MUTATION; PEDIGREE; RNA, TRANSFER, MET;

EID: 80054813903     PISSN: 10184813     EISSN: 14765438     Source Type: Journal    
DOI: 10.1038/ejhg.2011.111     Document Type: Article

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