Identification and Characterization of Novel Broad-Spectrum Inhibitors of the Flavivirus Methyltransferase

ACS Infectious Diseases

Volumn 1, Issue 8, 2016, Pages 340-349

  Brecher, Matthew ^a   Chen, Hui ^a   Li, Zhong ^a   Banavali, Nilesh K ^a,b   Jones, Susan A ^a   Zhang, Jing ^a   Kramer, Laura D ^a,b   Li, Hongmin ^a,b  

^a WADSWORTH CENTER   (United States)

^b STATE UNIVERSITY OF NEW YORK   (United States)

Author keywords

antiviral development; flavivirus NS5; methyltransferase; RNA cap methylation; West Nile virus

Indexed keywords

ANTIVIRUS AGENT; METHYLTRANSFERASE INHIBITOR;

ARTICLE; BINDING SITE; CELL ASSAY; COMPETITIVE INHIBITION; CONTROLLED STUDY; CRYSTAL STRUCTURE; CYTOTOXICITY; DRUG EFFICACY; DRUG SCREENING; EC50; FLAVIVIRUS; NATIONAL HEALTH ORGANIZATION; NONHUMAN; PRIORITY JOURNAL; THERAPEUTIC INDEX; VIROGENESIS;

EID: 84969271146     PISSN: None     EISSN: 23738227     Source Type: Journal    
DOI: 10.1021/acsinfecdis.5b00070     Document Type: Article

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