-
1
-
-
84908403155
-
Human spaceflight: Find asteroids to get to Mars
-
Binzel, R. P. Human spaceflight: Find asteroids to get to Mars. Nature 514, 559-561 (2014).
-
(2014)
Nature
, vol.514
, pp. 559-561
-
-
Binzel, R.P.1
-
3
-
-
0346242743
-
The hazards of space travel
-
Setlow, R. B. The hazards of space travel. EMBO reports 4, 1013-1016 (2003).
-
(2003)
EMBO Reports
, vol.4
, pp. 1013-1016
-
-
Setlow, R.B.1
-
4
-
-
85007460924
-
Intrinsic cardiovascular autonomic regulatory system of astronauts exposed long-term to microgravity in space: Observational study
-
Otsuka, K. et al. Intrinsic cardiovascular autonomic regulatory system of astronauts exposed long-term to microgravity in space: observational study. npj Microgravity 1, Article number: 15018 (2015).
-
(2015)
Npj Microgravity
, vol.1
-
-
Otsuka, K.1
-
5
-
-
84951264358
-
Simulated microgravity inhibits L-type calcium channel currents partially by the up-regulation of miR-103 in MC3T3-E1 osteoblasts
-
Sun, Z. et al. Simulated microgravity inhibits L-type calcium channel currents partially by the up-regulation of miR-103 in MC3T3-E1 osteoblasts. Sci. Rep. 5, Article number: 8077 (2015).
-
(2015)
Sci. Rep.
, vol.5
-
-
Sun, Z.1
-
6
-
-
30044447065
-
Genitourinary issues during spaceflight: A review
-
Jones, J. A. et al. Genitourinary issues during spaceflight: a review. Int. J. Impot. Res. 17, S64-S67 (2005).
-
(2005)
Int. J. Impot. Res.
, vol.17
, pp. S64-S67
-
-
Jones, J.A.1
-
7
-
-
0035931895
-
Humans in space
-
White, R. J. & Averner, M. Humans in space. Nature 409, 1115-1118 (2001).
-
(2001)
Nature
, vol.409
, pp. 1115-1118
-
-
White, R.J.1
Averner, M.2
-
8
-
-
85038012068
-
Alterations in adaptive immunity persist during long-duration spaceflight
-
Crucian, B. et al. Alterations in adaptive immunity persist during long-duration spaceflight. npj Microgravity 1, 15013 (2015).
-
(2015)
Npj Microgravity
, vol.1
, pp. 15013
-
-
Crucian, B.1
-
9
-
-
84903625228
-
Dichotomal effect of space flight-associated microgravity on stress-activated protein kinases in innate immunity
-
Verhaar, A. P. et al. Dichotomal effect of space flight-associated microgravity on stress-activated protein kinases in innate immunity. Sci. Rep. 4, 5468 (2014).
-
(2014)
Sci. Rep.
, vol.4
, pp. 5468
-
-
Verhaar, A.P.1
-
10
-
-
84908215296
-
T cell regulation in microgravity - The current knowledge from in vitro experiments conducted in space, parabolic flights and ground-based facilities
-
Hauschilda, S. et al. T cell regulation in microgravity - The current knowledge from in vitro experiments conducted in space, parabolic flights and ground-based facilities. Acta Astronaut. 104, 365-377 (2014).
-
(2014)
Acta Astronaut.
, vol.104
, pp. 365-377
-
-
Hauschilda, S.1
-
11
-
-
84947649040
-
The impact of microgravity and hypergravity on endothelial cells
-
Maier, J. A. M. et al. The Impact of Microgravity and Hypergravity on Endothelial Cells. Biomed. Res. Int. 2015, 434803 (2015).
-
(2015)
Biomed. Res. Int.
, vol.2015
, pp. 434803
-
-
Maier, J.A.M.1
-
12
-
-
45349083936
-
Transcriptional analysis of normal human fibroblast responses to microgravity stress
-
Liu, Y. & Wang, E. Transcriptional Analysis of Normal Human Fibroblast Responses to Microgravity Stress. Genomics Proteomics Bioinformatics 6, 29-41 (2008).
-
(2008)
Genomics Proteomics Bioinformatics
, vol.6
, pp. 29-41
-
-
Liu, Y.1
Wang, E.2
-
13
-
-
84942883967
-
Genome wide expression profiling of cancer cell lines cultured in microgravity reveals significant dysregulation of cell cycle and MicroRNA gene networks
-
21
-
Vidyasekar, P. et al. Genome Wide Expression Profiling of Cancer Cell Lines Cultured in Microgravity Reveals Significant Dysregulation of Cell Cycle and MicroRNA Gene Networks. PLoS One. 21, 10(8), e0135958 (2015).
-
(2015)
PLoS One.
, vol.10
, Issue.8
, pp. e0135958
-
-
Vidyasekar, P.1
-
14
-
-
84887038087
-
The challenging environment on board the international space station affects endothelial cell function by triggering oxidative stress through thioredoxin interacting protein overexpression: The ESA-SPHINX experiment
-
Versari, S. et al. The challenging environment on board the International Space Station affects endothelial cell function by triggering oxidative stress through thioredoxin interacting protein overexpression: the ESA-SPHINX experiment. FASEB J. 7, 4466-4475 (2013).
-
(2013)
FASEB J.
, vol.7
, pp. 4466-4475
-
-
Versari, S.1
-
15
-
-
84870448663
-
The Rel/NF-κ B pathway and transcription of immediate early genes in T cell activation are inhibited by microgravity
-
Chang, T. T. et al. The Rel/NF-κ B pathway and transcription of immediate early genes in T cell activation are inhibited by microgravity. J. Leukoc. Biol. 2012, 92, 1133-1145 (2012).
-
(2012)
J. Leukoc. Biol.
, vol.2012
, Issue.92
, pp. 1133-1145
-
-
Chang, T.T.1
-
16
-
-
84871204114
-
Infection prevention and control during prolonged human space travel
-
Mermel, L. A. Infection Prevention and Control During Prolonged Human Space Travel. Clin. Infect. Dis. 56, 123-130 (2013).
-
(2013)
Clin. Infect. Dis.
, vol.56
, pp. 123-130
-
-
Mermel, L.A.1
-
17
-
-
0001792966
-
Clinical aspects of crew health
-
NASA Spec. Rep., Washington DC SP-368
-
Hawkins, W. R. & Ziegelschmid, J. F. Clinical aspects of crew health. Biomedical Results of Apollo. NASA Spec. Rep., Washington DC SP-368, 43-81 (1975).
-
(1975)
Biomedical Results of Apollo
, pp. 43-81
-
-
Hawkins, W.R.1
Ziegelschmid, J.F.2
-
18
-
-
84904102940
-
Integration analysis of microRNA and mRNA expression profiles in human peripheral blood lymphocytes cultured in modeled microgravity
-
Girardi, C. et al. Integration analysis of microRNA and mRNA expression profiles in human peripheral blood lymphocytes cultured in modeled microgravity. Biomed. Res. Int. 2014, 296747 (2014).
-
(2014)
Biomed. Res. Int.
, vol.2014
, pp. 296747
-
-
Girardi, C.1
-
19
-
-
80052783075
-
Effects of simulated microgravity on expression profile of MicroRNA in human lymphoblastoid cells
-
Mangala, L. S. et al. Effects of Simulated Microgravity on Expression Profile of MicroRNA in Human Lymphoblastoid Cells. J. Biol. Chem. 286, 32483-32490 (2011).
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 32483-32490
-
-
Mangala, L.S.1
-
20
-
-
33750545620
-
Gene expression alterations in activated human t-cells induced by modeled microgravity
-
Ward, N. E. et al. Gene Expression Alterations in Activated Human T-Cells Induced by Modeled Microgravity. J. Cell. Biochem. 99, 1187-1202 (2006).
-
(2006)
J. Cell. Biochem.
, vol.99
, pp. 1187-1202
-
-
Ward, N.E.1
-
21
-
-
27344435774
-
Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
-
Subramanian, A. et al. Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles. Proc Natl Acad Sci USA 102, 15545-15550 (2005).
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 15545-15550
-
-
Subramanian, A.1
-
22
-
-
0037477855
-
Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1
-
Patti, M. E. et al. Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1. Proc. Natl. Acad. Sci. USA 100, 8466-8471 (2003).
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 8466-8471
-
-
Patti, M.E.1
-
23
-
-
3242813597
-
Differential gene expression in ovarian carcinoma: Identification of potential biomarkers
-
Hibbs, K. et al. Differential Gene Expression in Ovarian Carcinoma: Identification of Potential Biomarkers. Am. J. Pathol. 165, 397-414 (2004).
-
(2004)
Am. J. Pathol.
, vol.165
, pp. 397-414
-
-
Hibbs, K.1
-
24
-
-
84920578473
-
Identification of biomarkers in breast cancer by gene expression profiling using human tissues
-
Fu, J. et al. Identification of biomarkers in breast cancer by gene expression profiling using human tissues. Genom. Data. 2, 299-301 (2014).
-
(2014)
Genom. Data.
, vol.2
, pp. 299-301
-
-
Fu, J.1
-
25
-
-
0033592606
-
Learning the parts of objects by non-negative matrix factorization
-
Lee, D. D. & Seung, H. S. Learning the parts of objects by non-negative matrix factorization. Nature 401, 788-791 (1999).
-
(1999)
Nature
, vol.401
, pp. 788-791
-
-
Lee, D.D.1
Seung, H.S.2
-
26
-
-
1642529511
-
Metagenes and molecular pattern discovery using matrix factorization
-
Brunet, J. P. et al. Metagenes and molecular pattern discovery using matrix factorization. Proc. Natl. Acad. Sci. USA 101, 4164-4169 (2004).
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 4164-4169
-
-
Brunet, J.P.1
-
27
-
-
48249151183
-
Nonnegative matrix factorization: An analytical and interpretive tool in computational biology
-
Devarajan, K. Nonnegative Matrix Factorization: An Analytical and Interpretive Tool in Computational Biology. PLoS Comput. Biol. 47, e1000029 (2008).
-
(2008)
PLoS Comput. Biol.
, vol.47
, pp. e1000029
-
-
Devarajan, K.1
-
28
-
-
0037810449
-
Subsystem identification through dimensionality reduction of large-scale gene expression data
-
Kim, P. & Tidor, B. Subsystem identification through dimensionality reduction of large-scale gene expression data. Genome Res. 13, 1706-1718 (2003).
-
(2003)
Genome Res.
, vol.13
, pp. 1706-1718
-
-
Kim, P.1
Tidor, B.2
-
29
-
-
84876515907
-
STRING v9.1: Protein-protein interaction networks, with increased coverage and integration
-
Franceschini, A. et al. STRING v9.1: protein-protein interaction networks, with increased coverage and integration. Nucl. Acids Res. 41, D808-D815 (2013).
-
(2013)
Nucl. Acids Res.
, vol.41
, pp. D808-D815
-
-
Franceschini, A.1
-
30
-
-
70349249979
-
Notch1 upregulates LPS-induced macrophage activation by increasing NF-jB activity
-
Monsalve, E. et al. Notch1 upregulates LPS-induced macrophage activation by increasing NF-jB activity. Eur. J. Immunol. 39, 2556-2570 (2009).
-
(2009)
Eur. J. Immunol.
, vol.39
, pp. 2556-2570
-
-
Monsalve, E.1
-
31
-
-
84865189146
-
NFAT control of innate immunity
-
Fric, J. et al. NFAT control of innate immunity. Blood 120, 1380-1389 (2012).
-
(2012)
Blood
, vol.120
, pp. 1380-1389
-
-
Fric, J.1
-
32
-
-
84858976269
-
2+ mobilization and nuclear factor of activated T cells (NFAT) activation
-
2+ mobilization and nuclear factor of activated T cells (NFAT) activation. J. Biol. Chem. 287, 10200-10209 (2012).
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 10200-10209
-
-
Kliem, C.1
-
33
-
-
84899746859
-
Space radiation risks for astronauts on multiple international space station missions
-
Cucinotta, F. A. Space Radiation Risks for Astronauts on Multiple International Space Station Missions. PLoS ONE 9(4), e96099 (2014).
-
(2014)
PLoS ONE
, vol.9
, Issue.4
, pp. e96099
-
-
Cucinotta, F.A.1
-
34
-
-
33846903838
-
Cytokine receptor signaling through the Jak-Stat-Socs pathway in disease
-
O'Sullivan, L. A. et al. Cytokine receptor signaling through the Jak-Stat-Socs pathway in disease. Mol. Immunol. 44, 2497-2506 (2007).
-
(2007)
Mol. Immunol.
, vol.44
, pp. 2497-2506
-
-
O'Sullivan, L.A.1
-
35
-
-
84901752701
-
Mitochondrial dysfunctions in neurodegenerative diseases: Relevance to Alzheimer's disease
-
Hroudová, J. et al. Mitochondrial Dysfunctions in Neurodegenerative Diseases: Relevance to Alzheimer's Disease. BioMed. Res. Int. 2014, 175062 (2014).
-
(2014)
BioMed. Res. Int.
, vol.2014
, pp. 175062
-
-
Hroudová, J.1
-
36
-
-
84939864925
-
2015 mitochondrial and ubiquitin proteasome system dysfunction in ageing and disease: Two sides of the same coin?
-
Ross, J. M. et al. 2015 Mitochondrial and Ubiquitin Proteasome System Dysfunction in Ageing and Disease: Two Sides of the Same Coin? Int. J. Mol. Sci. 16, 19458-19476 (2015).
-
(2015)
Int. J. Mol. Sci.
, vol.16
, pp. 19458-19476
-
-
Ross, J.M.1
-
37
-
-
0028539762
-
Fluid dynamics within rotating bioreactor in space and earth environment
-
Tsao, Y. M. D. et al. Fluid dynamics within rotating bioreactor in space and earth environment. J. spacecrafts rockets. 31, 937-945 (1994).
-
(1994)
J. Spacecrafts Rockets.
, vol.31
, pp. 937-945
-
-
Tsao, Y.M.D.1
-
38
-
-
2942532125
-
Microbial responses to microgravity and other low-shear environments
-
Nickerson, C. A. et al. Microbial Responses to Microgravity and Other Low-Shear Environments. Microbiol Mol Biol Rev. 68, 345-361 (2004).
-
(2004)
Microbiol Mol Biol Rev.
, vol.68
, pp. 345-361
-
-
Nickerson, C.A.1
-
39
-
-
0027462466
-
Flow-related responses of intracellular inositol phosphate levels in cultured aortic endothelial cells
-
Prasad, A. R. S. et al. Flow-Related Responses of Intracellular Inositol Phosphate Levels in Cultured Aortic Endothelial Cells. Circ. Res. 72, 827-836 (1993).
-
(1993)
Circ. Res.
, vol.72
, pp. 827-836
-
-
Prasad, A.R.S.1
-
40
-
-
0030891305
-
A mathematical model of the cytosolic-free calcium response in endothelial cells to fluid shear stress
-
Wiesner, T. et al. A mathematical model of the cytosolic-free calcium response in endothelial cells to fluid shear stress. Proc. Natl. Acad. Sci. USA 94, 3726-3731 (1997).
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 3726-3731
-
-
Wiesner, T.1
-
41
-
-
84923681930
-
JAK-STAT and bone metabolism
-
Licorresponding, J. JAK-STAT and bone metabolism. JAKSTAT. 2, e23930 (2013).
-
(2013)
JAKSTAT
, vol.2
, pp. e23930
-
-
Licorresponding, J.1
-
42
-
-
84876798249
-
An update to space biomedical research: Tissue engineering in microgravity bioreactor
-
Barzegari, A. & Saei, A. A. An update to space biomedical research: Tissue engineering in microgravity bioreactor. Bioimpacts. 2, 23-32 (2012).
-
(2012)
Bioimpacts
, vol.2
, pp. 23-32
-
-
Barzegari, A.1
Saei, A.A.2
-
43
-
-
0035983877
-
The effect of microgravity and space flight on the chemical senses
-
Olabi, A. A. et al. The effect of microgravity and space flight on the chemical senses. J. Food Sci. 67, 468-478 (2002).
-
(2002)
J. Food Sci.
, vol.67
, pp. 468-478
-
-
Olabi, A.A.1
|