Genome wide expression profiling of cancer cell lines cultured in microgravity reveals significant dysregulation of cell cycle and MicroRNA gene networks

PLoS ONE

Volumn 10, Issue 8, 2015, Pages

  Vidyasekar, Prasanna ^a   Shyamsunder, Pavithra ^a   Arun, Rajpranap ^a   Santhakumar, Rajalakshmi ^a   Kapadia, Nand Kishore ^b   Kumar, Ravi ^c   Verma, Rama Shanker ^a  

^a INDIAN INSTITUTE OF TECHNOLOGY MADRAS   (India)

^b Global Hospitals   (India)

^c Fortis Malar Hospital   (India)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN A2; CYCLIN DEPENDENT KINASE 6; MICRORNA; MICRORNA 22; TRANSCRIPTION FACTOR SP1; TUMOR MARKER; CELL CYCLE PROTEIN; ONCOPROTEIN;

APOPTOSIS; ARTICLE; CANCER GROWTH; CANCER PROGNOSIS; CCNA2 GENE; CDK6 GENE; CELL ACTIVITY; CELL CYCLE REGULATION; CELL POPULATION; CELL PROLIFERATION; CELL STRUCTURE; CELL TRANSFORMATION; CELL VIABILITY; COLONY FORMATION; COLORECTAL CANCER CELL LINE; CONTROLLED STUDY; DLD 1 CELL LINE; DNA MICROARRAY; DOWN REGULATION; GENE CONTROL; GENE EXPRESSION PROFILING; GENE ONTOLOGY; GENE SILENCING; GENE TARGETING; GENOME ANALYSIS; LEUKEMIA CELL LINE; MICROGRAVITY; MIR17HG GENE; MIR21HG GENE; MIR22HG GENE; MOLT 4 CELL LINE; ONCOGENE; PROTO ONCOGENE; REGULATORY MECHANISM; SIMULATION; SP1 GENE; TRANSCRIPTION REGULATION; TUMOR SUPPRESSOR GENE; UPREGULATION; CELL CYCLE; GENE EXPRESSION REGULATION; GENE REGULATORY NETWORK; GENETICS; GENOME-WIDE ASSOCIATION STUDY; HUMAN; HUMAN GENOME; METABOLISM; SIGNAL TRANSDUCTION; TUMOR CELL LINE; WEIGHTLESSNESS;

CELL CYCLE; CELL CYCLE PROTEINS; CELL LINE, TUMOR; CELL PROLIFERATION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE REGULATORY NETWORKS; GENOME, HUMAN; GENOME-WIDE ASSOCIATION STUDY; HUMANS; MICRORNAS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PROTO-ONCOGENE PROTEINS; SIGNAL TRANSDUCTION; WEIGHTLESSNESS SIMULATION;

EID: 84942883967     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0135958     Document Type: Article

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