The Rel/NF-κB pathway and transcription of immediate early genes in T cell activation are inhibited by microgravity

Journal of Leukocyte Biology

Volumn 92, Issue 6, 2012, Pages 1133-1145

  Chang, Tammy T ^a   Walther, Isabelle ^b   Li, Chai Fei ^c,d   Boonyaratanakornkit, Jim ^d   Galleri, Grazia ^e   Meloni, Maria Antonia ^f   Pippia, Proto ^a   Cogoli, Augusto ^a   Hughes Fulford, Millie ^a,c,d  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b ETH ZURICH   (Switzerland)

^c NORTHERN CALIFORNIA INSTITUTE FOR RESEARCH AND EDUCATION   (United States)

^d SAN FRANCISCO VETERANS AFFAIRS MEDICAL CENTER   (United States)

^e UNIVERSITY OF SASSARI   (Italy)

^f Zero g Life Tec   (Switzerland)

Author keywords

Immunosuppression; Microarray; Spaceflight; TNF

Indexed keywords

CD69 ANTIGEN; CD83 ANTIGEN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERFERON REGULATORY FACTOR 4; INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR ALPHA; KRUPPEL LIKE FACTOR; TRANSCRIPTION FACTOR REL; ZINC FINGER PROTEIN;

APOPTOSIS; ARTICLE; CD4+ T LYMPHOCYTE; CELL CYCLE REGULATION; CELL ISOLATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOWN REGULATION; GENE TARGETING; GENETIC TRANSCRIPTION; HOST RESISTANCE; HUMAN; HUMAN CELL; INHIBITION KINETICS; LYMPHOCYTE DIFFERENTIATION; LYMPHOCYTE PROLIFERATION; MICROARRAY ANALYSIS; MICROGRAVITY; NORMAL HUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPACE FLIGHT; SPLEEN CELL; T LYMPHOCYTE ACTIVATION; TRANSACTIVATION; TRANSCRIPTION REGULATION;

ANTIGENS, CD28; ANTIGENS, CD3; CD4-POSITIVE T-LYMPHOCYTES; CLUSTER ANALYSIS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE REGULATORY NETWORKS; GENES, IMMEDIATE-EARLY; HUMANS; LYMPHOCYTE ACTIVATION; NF-KAPPA B; SIGNAL TRANSDUCTION; T-LYMPHOCYTES; TRANSCRIPTION FACTOR RELA; TRANSCRIPTION, GENETIC; TUMOR NECROSIS FACTOR-ALPHA; WEIGHTLESSNESS;

EID: 84870448663     PISSN: 07415400     EISSN: 19383673     Source Type: Journal    
DOI: 10.1189/jlb.0312157     Document Type: Article

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