Ferulic Acid Administered at Various Time Points Protects against Cerebral Infarction by Activating p38 MAPK/p90RSK/CREB/Bcl-2 Anti-Apoptotic Signaling in the Subacute Phase of Cerebral Ischemia-Reperfusion Injury in Rats

PLoS ONE

Volumn 11, Issue 5, 2016, Pages

  Cheng, Chin Yi ^a,b   Tang, Nou Ying ^a   Kao, Shung Te ^a   Hsieh, Ching Liang ^a,c  

^a CHINA MEDICAL UNIVERSITY   (Taiwan)

^b Department of Chinese Medicine Hui Sheng Hospital   (Taiwan)

^c CHINA MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; CYTOCHROME C; FERULIC ACID; GLIAL FIBRILLARY ACIDIC PROTEIN; MITOCHONDRIAL PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN BAD; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL XL; S6 KINASE; COUMARIC ACID; NEUROPROTECTIVE AGENT;

ACUTE DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN BLOOD FLOW; BRAIN INFARCTION; BRAIN INJURY; BRAIN ISCHEMIA; BRAIN PROTECTION; CONTROLLED STUDY; CYTOSOL; DOWN REGULATION; DRUG EFFECT; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; NEUROLOGIC DISEASE; NONHUMAN; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; RAT; REPERFUSION INJURY; SIGNAL TRANSDUCTION; THROMBECTOMY DEVICE; TREATMENT RESPONSE; UPREGULATION; ANIMAL; CEREBRAL INFARCTION; DRUG EFFECTS; METABOLISM; SPRAGUE DAWLEY RAT; TIME FACTOR;

ANIMALS; APOPTOSIS; CEREBRAL INFARCTION; COUMARIC ACIDS; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; MALE; MAP KINASE SIGNALING SYSTEM; NEUROPROTECTIVE AGENTS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; RATS, SPRAGUE-DAWLEY; REPERFUSION INJURY; RIBOSOMAL PROTEIN S6 KINASES, 90-KDA; TIME FACTORS;

EID: 84969180120     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0155748     Document Type: Article

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