Phosphorylation of p38 MAPK mediates hypoxic preconditioning-induced neuroprotection against cerebral ischemic injury via mitochondria translocation of Bcl-xL in mice

Brain Research

Volumn 1503, Issue , 2013, Pages 78-88

  Zhao, Li ^a   Liu, Xu ^a   Liang, Jing ^a   Han, Song ^a   Wang, Yue ^b   Yin, Yanling ^a   Luo, Yanlin ^a   Li, Junfa ^a  

^a BEIJING INSTITUTE FOR BRAIN DISORDERS   (China)

^b CAPITAL MEDICAL UNIVERSITY   (China)

Author keywords

Apoptosis; Bcl xL; Hypoxic preconditioning; Middle cerebral artery occlusion; Neuroprotection; Phosphorylation of p38 mitogen activated protein kinase

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN BCL 2; PROTEIN BCL XL;

ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; BRAIN; BRAIN INFARCTION; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; BRAIN MITOCHONDRION; BRAIN REGION; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; CYTOSOL; GROWTH INHIBITION; HYPOXIC PRECONDITIONING; ISCHEMIC PRECONDITIONING; MALE; MEDIATOR; MIDDLE CEREBRAL ARTERY OCCLUSION; MOUSE; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; RECEPTOR UPREGULATION;

ANIMALS; BCL-X PROTEIN; BRAIN EDEMA; BRAIN INFARCTION; DISEASE MODELS, ANIMAL; ENZYME INHIBITORS; IMIDAZOLES; IMMUNOPRECIPITATION; IN SITU NICK-END LABELING; INFARCTION, MIDDLE CEREBRAL ARTERY; ISCHEMIC PRECONDITIONING; MALE; MICE; MICE, INBRED BALB C; MITOCHONDRIA; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PROTEIN TRANSPORT; PYRIDINES; TIME FACTORS;

MUS;

EID: 84875211946     PISSN: 00068993     EISSN: 18726240     Source Type: Journal    
DOI: 10.1016/j.brainres.2013.01.051     Document Type: Article

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