Sialic Acid-Targeted Nanovectors with Phenylboronic Acid-Grafted Polyethylenimine Robustly Enhance siRNA-Based Cancer Therapy

ACS Applied Materials and Interfaces

Volumn 8, Issue 15, 2016, Pages 9565-9576

  Ji, Manyi ^a,b   Li, Ping ^a   Sheng, Nan ^a,b   Liu, Lanlan ^a   Pan, Hong ^a   Wang, Ce ^a   Cai, Lintao ^a   Ma, Yifan ^a  

^a SHENZHEN INSTITUTES OF ADVANCED TECHNOLOGY   (China)

^b UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA   (China)

Author keywords

cancer targeting; low molecular weight polyethylenimine; phenylboronic acid; sialic acid; siRNA delivery

Indexed keywords

BIOCOMPATIBILITY; CARBOXYLIC ACIDS; CELL CULTURE; CELL DEATH; CELLS; CYTOLOGY; DIAGNOSIS; DISEASES; GENE EXPRESSION; GRAFTING (CHEMICAL); MOLECULAR WEIGHT; ORGANIC ACIDS; RNA; TUMORS;

CANCER-TARGETING; PHENYLBORONIC ACIDS; POLYETHYLENIMINES; SIALIC ACIDS; SIRNA DELIVERY;

GENE THERAPY;

ANTINEOPLASTIC AGENT; BENZENEBORONIC ACID; BORONIC ACID DERIVATIVE; N ACETYLNEURAMINIC ACID; NANOPARTICLE; POLYETHYLENEIMINE; SMALL INTERFERING RNA;

ANIMAL; CELL DEATH; CHEMISTRY; DRUG EFFECTS; ENDOCYTOSIS; GENE SILENCING; HUMAN; METABOLISM; NEOPLASMS; NUDE MOUSE; PATHOLOGY; PROTON NUCLEAR MAGNETIC RESONANCE; SYNTHESIS; TISSUE DISTRIBUTION; TUMOR CELL LINE; ULTRASTRUCTURE;

ANIMALS; ANTINEOPLASTIC AGENTS; BORONIC ACIDS; CELL DEATH; CELL LINE, TUMOR; ENDOCYTOSIS; GENE SILENCING; HUMANS; MICE, NUDE; N-ACETYLNEURAMINIC ACID; NANOPARTICLES; NEOPLASMS; POLYETHYLENEIMINE; PROTON MAGNETIC RESONANCE SPECTROSCOPY; RNA, SMALL INTERFERING; TISSUE DISTRIBUTION;

EID: 84966440557     PISSN: 19448244     EISSN: 19448252     Source Type: Journal    
DOI: 10.1021/acsami.5b11866     Document Type: Article

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