Anti-tumor effects in mice induced by survivin-targeted siRNA delivered through polysaccharide nanoparticles

Biomaterials

Volumn 34, Issue 22, 2013, Pages 5689-5699

  Yang, Feifei ^a   Huang, Wei ^a   Li, Yunfei ^a   Liu, Shan ^a   Jin, Mingji ^a   Wang, Yuli ^c   Jia, Lihua ^d   Gao, Zhonggao ^a,b  

^a INSTITUTE OF MATERIA MEDICA   (China)

^b YANBIAN UNIVERSITY   (China)

^c BEIJING INSTITUTE OF MICROBIOLOGY AND EPIDEMIOLOGY   (China)

^d Beijing 307 Hospital   (China)

Author keywords

Anti tumor therapy; Nanoparticles; Non viral vector; Small interfering RNA; Survivin

Indexed keywords

ANTI-TUMOR ACTIVITIES; ANTI-TUMORS; AVERAGE PARTICLE SIZE; NONVIRAL VECTORS; POLYDISPERSITY INDICES; SMALL INTERFERING RNA; SMALL INTERFERING RNA (SIRNA); SURVIVIN;

BIOCOMPATIBILITY; CELL DEATH; GENE EXPRESSION; GENE EXPRESSION REGULATION; NANOPARTICLES; RNA; TUMORS; VECTORS; ZETA POTENTIAL;

GENE THERAPY;

CHITOSAN; COPOLYMER; LUCIFERASE; NANOPARTICLE; POLYSACCHARIDE; SMALL INTERFERING RNA; SURVIVIN; TRANSACTIVATOR PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; BIOCOMPATIBILITY; CANCER GENE THERAPY; CELL VIABILITY; COMPLEX FORMATION; CONTROLLED STUDY; CYTOTOXICITY; DISPERSION; DOWN REGULATION; DRUG UPTAKE; EXPRESSION VECTOR; FEMALE; FLOW CYTOMETRY; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; IN VIVO GENE TRANSFER; INFRARED SPECTROSCOPY; MOUSE; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; PARTICLE SIZE; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; REPORTER GENE; SYNTHESIS; TRANSMISSION ELECTRON MICROSCOPY; TUMOR CELL; ZETA POTENTIAL;

ANIMALS; ANTINEOPLASTIC AGENTS; CELL DEATH; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; CHITOSAN; DOWN-REGULATION; ELECTROPHORETIC MOBILITY SHIFT ASSAY; ENDOCYTOSIS; FEMALE; HUMANS; INHIBITOR OF APOPTOSIS PROTEINS; LUCIFERASES; MICE; MICE, INBRED BALB C; NANOPARTICLES; NEOPLASMS; PARTICLE SIZE; PEPTIDES; REPRESSOR PROTEINS; RNA, SMALL INTERFERING; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; WOUND HEALING;

MUS;

EID: 84877594608     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2013.03.047     Document Type: Article

References (34)

1. Benson J.R., Jatoi I. The global breast cancer burden. Future Oncol 2012, 8(6):697-702.
2. Graham A., Adeloye D., Grant L., Theodoratou E., Campbell H. Estimating the incidence of colorectal cancer in Sub-Saharan Africa: a systematic analysis. JGlob Health 2012, 2(2):20404.
3. Jha K., Shukla M., Pandey M. Survivin expression and targeting in breast cancer. Surg Oncol 2012, 21(2):125-131.
4. Moriai R., Tsuji N., Moriai M., Kobayashi D., Watanabe N. Survivin plays as a resistant factor against tamoxifen-induced apoptosis in human breast cancer cells. Breast Cancer Res Treat 2009, 117(2):261-271.
5. Yang Y., Gao Y., Chen L., Huang Y., Li Y. Downregulation of survivin expression and enhanced chemosensitivity of MCF-7 cells to adriamycin by PDMAE/survivin shRNA complex nanoparticles. Int J Pharm 2011, 405(1-2):188-195.
6. Zu X., Ma J., Liu H., Liu F., Tan C., Yu L., et al. Pro-oncogene Pokemon promotes breast cancer progression by upregulating survivin expression. Breast Cancer Res 2011, 13(2):R26.
7. Vegran F., Boidot R., Bonnetain F., Cadouot M., Chevrier S., Lizard-Nacol S. Apoptosis gene signature of survivin and its splice variant expression in breast carcinoma. Endocr Relat Cancer 2011, 18(6):783-792.
8. Croci D.O., Cogno I.S., Vittar N.B., Salvatierra E., Trajtenberg F., Podhajcer O.L., et al. Silencing survivin gene expression promotes apoptosis of human breast cancer cells through a caspase-independent pathway. JCell Biochem 2008, 105(2):381-390.
9. Wang Y., Li Z., Han Y., Liang L.H., Ji A. Nanoparticle-based delivery system for application of siRNA invivo. Curr Drug Metab 2010, 11(2):182-196.
10. Tokatlian T., Segura T. siRNA application in nanomedicine. Wiley Interdiscip Rev Nanomed Nanobiotechnol 2010, 2(3):305-315.
11. Oh Y.K., Park T.G. siRNA delivery systems for cancer treatment. Adv Drug Deliv Rev 2009, 61(10):850-862.
12. Montazeri Aliabadi H., Landry B., Mahdipoor P., Uludag H. Induction of apoptosis by survivin silencing through siRNA delivery in a human breast cancer cell line. Mol Pharm 2011, 8(5):1821-1830.
13. Shim M.S., Kwon Y.J. Efficient and targeted delivery of siRNA invivo. FEBS J 2010, 277(23):4814-4827.
14. Whitehead K.A., Langer R., Anderson D.G. Knocking down barriers: advances in siRNA delivery. Nat Rev Drug Discov 2009, 8(2):129-138.
15. Tamura A., Nagasaki Y. Smart siRNA delivery systems based on polymeric nanoassemblies and nanoparticles. Nanomedicine 2010, 5(7):1089-1102.
16. Posadas I., Guerra F.J., Ceña V. Nonviral vectors for the delivery of small interfering RNAs to the CNS. Nanomedicine 2010, 5(8):1219-1236.
17. Gao Y., Liu X.L., Li X.R. Research progress on siRNA delivery with nonviral carriers. Int J Nanomedicine 2011, 6:1017-1025.
18. Nagpal K., Singh S.K., Mishra D.N. Chitosan nanoparticles: a promising system in novel drug delivery. Chem Pharm Bull 2010, 58(11):1423-1430.
19. Saranya N., Moorthi A., Saravanan S., Devi M.P., Selvamurugan N. Chitosan and its derivatives for gene delivery. Int J Biol Macromol 2011, 48(2):234-238.
20. Katas H., Dzulkefli N.N.S.N., Shariza S. Synthesis of a new potential conjugated TAT-peptide-chitosan nanoparticles carrier via disulphide linkage. JNanomater 2012, 10.1155/2012/134607.
21. Singha K., Namgung R., Kim W.J. Polymers in small-interfering RNA delivery. Nucleic Acid Ther 2011, 21(3):133-147.
22. Mao S., Sun W., Kissel T. Chitosan-based formulations for delivery of DNA and siRNA. Adv Drug Deliv Rev 2010, 62(1):12-27.
23. Lee J.Y., Lee S.H., Oh M.H., Kim J.S., Park T.G., Nam Y.S. Prolonged gene silencing by siRNA/chitosan-g-deoxycholic acid polyplexes loaded within biodegradable polymer nanoparticles. JControl Release 2012, 162(2):407-413.
24. Meade B.R., Dowdy S.F. Enhancing the cellular uptake of siRNA duplexes following noncovalent packaging with protein transduction domain peptides. Adv Drug Deliv Rev 2008, 60(4-5):530-536.
25. Gary D.J., Puri N., Won Y.Y. Polymer-based siRNA delivery: perspectives on the fundamental and phenomenological distinctions from polymer-based DNA delivery. JControl Release 2007, 121(1-2):64-73.
26. Kim S.S., Garg H., Joshi A., Manjunath N. Strategies for targeted nonviral delivery of siRNAs invivo. Trends Mol Med 2009, 15(11):491-500.
27. Deshayes S., Morris M.C., Divita G., Heitz F. Cell-penetrating peptides: tools for intracellular delivery of therapeutics. Cell Mol Life Sci 2005, 62(16):1839-1849.
28. Zhang S., Zhao Y., Zhi D., Zhang S. Non-viral vectors for the mediation of RNAi. Bioorg Chem 2012, 40(1):10-18.
29. Singer S.J., Nicolson G.L. The fluid mosaic model of the structure of cell membranes. Science 1972, 175(4023):720-731.
30. Huth U.S., Schubert R., Peschka-Suss R. Investigating the uptake and intracellular fate of pH-sensitive liposomes by flow cytometry and spectral bio-imaging. JControl Release 2006, 110(3):490-504.
31. Nimesh S., Gupta N., Chandra R. Strategies and advances in nanomedicine for targeted siRNA delivery. Nanomedicine 2011, 6(4):729-746.
32. Carrasco R.A., Stamm N.B., Marcusson E., Sandusky G., Iversen P., Patel B.K. Antisense inhibition of survivin expression as a cancer therapeutic. Mol Cancer Ther 2011, 10(2):221-232.
33. Beloor J., Choi C.S., Nam H.Y., Park M., Kim S.H., Jackson A., et al. Arginine-engrafted biodegradable polymer for the systemic delivery of therapeutic siRNA. Biomaterials 2012, 33(5):1640-1650.
34. Panigrahy D., Edin M.L., Lee C.R., Huang S., Bielenberg D.R., Butterfield C.E., et al. Epoxyeicosanoids stimulate multiorgan metastasis and tumor dormancy escape in mice. JClin Invest 2012, 122(1):178-191.