Phenylboronic acid-sugar grafted polymer architecture as a dual stimuli-responsive gene carrier for targeted anti-angiogenic tumor therapy

Biomaterials

Volumn 75, Issue , 2016, Pages 102-111

  Kim, Jinhwan ^a   Lee, Yeong Mi ^b   Kim, Hyunwoo ^a   Park, Dongsik ^a   Kim, Jihoon ^b   Kim, Won Jong ^a,b  

^a Pohang University of Science and Technology (POSTECH)   (South Korea)

^b Institute for Basic Science   (South Korea)

Author keywords

Anti angiogenesis; Gene delivery; Intracellular stimuli; Phenylboronic acid; Tumor targeting

Indexed keywords

BINS; CHEMICAL BONDS; CROSSLINKING; CYTOLOGY; FUNCTIONAL POLYMERS; GENE TRANSFER; GENES; ORGANIC ACIDS; POLYMERS; TUMORS;

ANGIOGENESIS; GENE DELIVERY; INTRACELLULAR STIMULI; PHENYLBORONIC ACIDS; TUMOR TARGETING;

GENE THERAPY;

ADENOSINE TRIPHOSPHATE; BENZENEBORONIC ACID; DNA; MACROGOL; POLYETHYLENEIMINE; POLYMER; SIALOGLYCOPROTEIN; SUGAR; ANTINEOPLASTIC AGENT; BORONIC ACID DERIVATIVE; CARBOHYDRATE; MACROGOL DERIVATIVE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIANGIOGENIC GENE THERAPY; ARTICLE; CANCER INHIBITION; CANCER SIZE; CANCER THERAPY; CELL MEMBRANE; CELL VIABILITY; CHEMICAL BINDING; CONTROLLED STUDY; CROSS LINKING; CYTOTOXICITY; DNA TRANSFECTION; DRUG DNA INTERACTION; ENDOSOME; FEMALE; GENE VECTOR; HUMAN; HUMAN CELL; IN VITRO GENE TRANSFER; IN VITRO STUDY; IN VIVO STUDY; MALE; MOLECULAR WEIGHT; MOUSE; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; PH; PRIORITY JOURNAL; PROTEIN EXPRESSION; TUMOR CELL; AGAR GEL ELECTROPHORESIS; ANIMAL; CELL DEATH; CELL SURVIVAL; CHEMISTRY; DRUG EFFECTS; GENETIC TRANSFECTION; GENETICS; METABOLISM; MOLECULARLY TARGETED THERAPY; NEOPLASM; NEOVASCULARIZATION, PATHOLOGIC; PATHOLOGY; PLASMID; TISSUE DISTRIBUTION; TUMOR CELL LINE; VASCULARIZATION;

ANIMALS; ANTINEOPLASTIC AGENTS; BORONIC ACIDS; CARBOHYDRATES; CELL DEATH; CELL LINE, TUMOR; CELL SURVIVAL; DNA; ELECTROPHORESIS, AGAR GEL; GENETIC VECTORS; HUMANS; MICE; MOLECULAR TARGETED THERAPY; NEOPLASMS; NEOVASCULARIZATION, PATHOLOGIC; PLASMIDS; POLYETHYLENE GLYCOLS; POLYMERS; TISSUE DISTRIBUTION; TRANSFECTION;

EID: 84946423231     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2015.10.022     Document Type: Article

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