-
1
-
-
84886698315
-
Innate and adaptive immune cells in the tumor microenvironment
-
COI: 1:CAS:528:DC%2BC3sXhsVKgu7vL, PID: 24048123
-
Gajewski TF, Schreiber H, Fu YX (2013) Innate and adaptive immune cells in the tumor microenvironment. Nat Immunol 14:1014–1022
-
(2013)
Nat Immunol
, vol.14
, pp. 1014-1022
-
-
Gajewski, T.F.1
Schreiber, H.2
Fu, Y.X.3
-
2
-
-
84923027892
-
Immune cell promotion of metastasis
-
COI: 1:CAS:528:DC%2BC2MXhsVarsb8%3D, PID: 25614318
-
Kitamura T, Qian BZ, Pollard JW (2015) Immune cell promotion of metastasis. Nat Rev Immunol 15:73–86
-
(2015)
Nat Rev Immunol
, vol.15
, pp. 73-86
-
-
Kitamura, T.1
Qian, B.Z.2
Pollard, J.W.3
-
3
-
-
84905381214
-
The tumour-induced systemic environment as a critical regulator of cancer progression and metastasis
-
COI: 1:CAS:528:DC%2BC2cXht1Ghtb%2FJ, PID: 25082194
-
McAllister SS, Weinberg RA (2014) The tumour-induced systemic environment as a critical regulator of cancer progression and metastasis. Nat Cell Biol 16:717–727
-
(2014)
Nat Cell Biol
, vol.16
, pp. 717-727
-
-
McAllister, S.S.1
Weinberg, R.A.2
-
4
-
-
84887444879
-
Microenvironmental regulation of tumor progression and metastasis
-
COI: 1:CAS:528:DC%2BC3sXhslCmsrjL, PID: 24202395
-
Quail DF, Joyce JA (2013) Microenvironmental regulation of tumor progression and metastasis. Nat Med 19:1423–1437
-
(2013)
Nat Med
, vol.19
, pp. 1423-1437
-
-
Quail, D.F.1
Joyce, J.A.2
-
5
-
-
79953059789
-
Natural innate and adaptive immunity to cancer
-
COI: 1:CAS:528:DC%2BC3MXltlKns7s%3D, PID: 21219185
-
Vesely MD, Kershaw MH, Schreiber RD, Smyth MJ (2011) Natural innate and adaptive immunity to cancer. Annu Rev Immunol 29:235–271
-
(2011)
Annu Rev Immunol
, vol.29
, pp. 235-271
-
-
Vesely, M.D.1
Kershaw, M.H.2
Schreiber, R.D.3
Smyth, M.J.4
-
6
-
-
79952284127
-
Hallmarks of cancer: the next generation
-
COI: 1:CAS:528:DC%2BC3MXjsFeqtrk%3D, PID: 21376230
-
Hanahan D, Weinberg RA (2011) Hallmarks of cancer: the next generation. Cell 144:646–674
-
(2011)
Cell
, vol.144
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
7
-
-
84901207693
-
Cancer immunology. Identifying the infiltrators
-
COI: 1:CAS:528:DC%2BC2cXpvVWgtb8%3D, PID: 24855239
-
Gomez Perdiguero E, Geissmann F (2014) Cancer immunology. Identifying the infiltrators. Science 344:801–802
-
(2014)
Science
, vol.344
, pp. 801-802
-
-
Gomez Perdiguero, E.1
Geissmann, F.2
-
8
-
-
34047220868
-
Cancer immunoediting from immune surveillance to immune escape
-
COI: 1:CAS:528:DC%2BD2sXltFarsb8%3D, PID: 17386080
-
Kim R, Emi M, Tanabe K (2007) Cancer immunoediting from immune surveillance to immune escape. Immunology 121:1–14
-
(2007)
Immunology
, vol.121
, pp. 1-14
-
-
Kim, R.1
Emi, M.2
Tanabe, K.3
-
9
-
-
79953151458
-
Cancer immunoediting: integrating immunity’s roles in cancer suppression and promotion
-
COI: 1:CAS:528:DC%2BC3MXjs1Cgtbs%3D, PID: 21436444
-
Schreiber RD, Old LJ, Smyth MJ (2011) Cancer immunoediting: integrating immunity’s roles in cancer suppression and promotion. Science 331:1565–1570
-
(2011)
Science
, vol.331
, pp. 1565-1570
-
-
Schreiber, R.D.1
Old, L.J.2
Smyth, M.J.3
-
10
-
-
84926160709
-
Immune evasion in cancer: mechanistic basis and therapeutic strategies
-
Vinay DS, Ryan EP, Pawelec G, Talib WH, Stagg J, Elkord E, Lichtor T, Decker WK, Whelan RL, Kumara HM et al. (2015) Immune evasion in cancer: mechanistic basis and therapeutic strategies. Semin Cancer Biol DOI 10.1016/j.semcancer.2015.03.004.
-
(2015)
Semin Cancer Biol DOI 10.1016/j.semcancer.2015
, vol.3
, pp. 004
-
-
Vinay, D.S.1
Ryan, E.P.2
Pawelec, G.3
Talib, W.H.4
Stagg, J.5
Elkord, E.6
Lichtor, T.7
Decker, W.K.8
Whelan, R.L.9
Kumara, H.M.10
-
11
-
-
84925221855
-
PD-1 blockade with nivolumab in relapsed or refractory Hodgkin’s lymphoma
-
PID: 25482239
-
Ansell SM, Lesokhin AM, Borrello I, Halwani A, Scott EC, Gutierrez M, Schuster SJ, Millenson MM, Cattry D, Freeman GJ et al (2015) PD-1 blockade with nivolumab in relapsed or refractory Hodgkin’s lymphoma. N Engl J Med 372:311–319
-
(2015)
N Engl J Med
, vol.372
, pp. 311-319
-
-
Ansell, S.M.1
Lesokhin, A.M.2
Borrello, I.3
Halwani, A.4
Scott, E.C.5
Gutierrez, M.6
Schuster, S.J.7
Millenson, M.M.8
Cattry, D.9
Freeman, G.J.10
-
12
-
-
84894107349
-
New insights into cancer immunoediting and its three component phases—elimination, equilibrium and escape
-
COI: 1:CAS:528:DC%2BC2cXmtVWktL4%3D, PID: 24531241
-
Mittal D, Gubin MM, Schreiber RD, Smyth MJ (2014) New insights into cancer immunoediting and its three component phases—elimination, equilibrium and escape. Curr Opin Immunol 27:16–25
-
(2014)
Curr Opin Immunol
, vol.27
, pp. 16-25
-
-
Mittal, D.1
Gubin, M.M.2
Schreiber, R.D.3
Smyth, M.J.4
-
13
-
-
84878725584
-
Immunology: an innate regulatory cell
-
COI: 1:CAS:528:DC%2BC3sXovFaksLc%3D, PID: 23739420
-
Colonna M (2013) Immunology: an innate regulatory cell. Nature 498:42–43
-
(2013)
Nature
, vol.498
, pp. 42-43
-
-
Colonna, M.1
-
14
-
-
84973432271
-
CCR 20th Anniversary Commentary: from regulatory T cells to checkpoint monoclonal antibodies-immuno-oncology advances clinical cancer research
-
COI: 1:CAS:528:DC%2BC2MXhtVajurbL, PID: 26078428
-
Wolf D, Wolf AM (2015) CCR 20th Anniversary Commentary: from regulatory T cells to checkpoint monoclonal antibodies-immuno-oncology advances clinical cancer research. Clin Cancer Res 21:2657–2659
-
(2015)
Clin Cancer Res
, vol.21
, pp. 2657-2659
-
-
Wolf, D.1
Wolf, A.M.2
-
15
-
-
84871856775
-
Therapeutic opportunities for manipulating T(Reg) cells in autoimmunity and cancer
-
von Boehmer H, Daniel C (2013) Therapeutic opportunities for manipulating T(Reg) cells in autoimmunity and cancer. Nat Rev Drug Discov 12:51–63
-
(2013)
Nat Rev Drug Discov
, vol.12
, pp. 51-63
-
-
von Boehmer, H.1
Daniel, C.2
-
16
-
-
79960393113
-
Tumour hypoxia promotes tolerance and angiogenesis via CCL28 and T(reg) cells
-
COI: 1:CAS:528:DC%2BC3MXovFegs7g%3D, PID: 21753853
-
Facciabene A, Peng X, Hagemann IS, Balint K, Barchetti A, Wang LP, Gimotty PA, Gilks CB, Lal P, Zhang L et al (2011) Tumour hypoxia promotes tolerance and angiogenesis via CCL28 and T(reg) cells. Nature 475:226–230
-
(2011)
Nature
, vol.475
, pp. 226-230
-
-
Facciabene, A.1
Peng, X.2
Hagemann, I.S.3
Balint, K.4
Barchetti, A.5
Wang, L.P.6
Gimotty, P.A.7
Gilks, C.B.8
Lal, P.9
Zhang, L.10
-
17
-
-
84899900047
-
Human hepatocellular carcinoma-infiltrating CD4(+)CD69(+)Foxp3(−) regulatory T cell suppresses T cell response via membrane-bound TGF-beta1
-
COI: 1:CAS:528:DC%2BC2cXkslGntbw%3D
-
Han Y, Yang Y, Chen Z, Jiang Z, Gu Y, Liu Y, Xu S, Lin C, Pan Z, Zhou W et al (2014) Human hepatocellular carcinoma-infiltrating CD4(+)CD69(+)Foxp3(−) regulatory T cell suppresses T cell response via membrane-bound TGF-beta1. J Mol Med (Berl) 92:539–550
-
(2014)
J Mol Med (Berl)
, vol.92
, pp. 539-550
-
-
Han, Y.1
Yang, Y.2
Chen, Z.3
Jiang, Z.4
Gu, Y.5
Liu, Y.6
Xu, S.7
Lin, C.8
Pan, Z.9
Zhou, W.10
-
18
-
-
84908003234
-
The stress-response sensor chop regulates the function and accumulation of myeloid-derived suppressor cells in tumors
-
COI: 1:CAS:528:DC%2BC2cXhsFyhur%2FP, PID: 25238096
-
Thevenot PT, Sierra RA, Raber PL, Al-Khami AA, Trillo-Tinoco J, Zarreii P, Ochoa AC, Cui Y, Del Valle L, Rodriguez PC (2014) The stress-response sensor chop regulates the function and accumulation of myeloid-derived suppressor cells in tumors. Immunity 41:389–401
-
(2014)
Immunity
, vol.41
, pp. 389-401
-
-
Thevenot, P.T.1
Sierra, R.A.2
Raber, P.L.3
Al-Khami, A.A.4
Trillo-Tinoco, J.5
Zarreii, P.6
Ochoa, A.C.7
Cui, Y.8
Del Valle, L.9
Rodriguez, P.C.10
-
19
-
-
84901334642
-
Disruption of CXCR2-mediated MDSC tumor trafficking enhances anti-PD1 efficacy
-
Highfill SL, Cui Y, Giles AJ, Smith JP, Zhang H, Morse E, Kaplan RN, Mackall CL (2014) Disruption of CXCR2-mediated MDSC tumor trafficking enhances anti-PD1 efficacy. Sci Transl Med 6:237ra267
-
(2014)
Sci Transl Med
, vol.6
, pp. 237267
-
-
Highfill, S.L.1
Cui, Y.2
Giles, A.J.3
Smith, J.P.4
Zhang, H.5
Morse, E.6
Kaplan, R.N.7
Mackall, C.L.8
-
20
-
-
84908054077
-
HMGB1 enhances immune suppression by facilitating the differentiation and suppressive activity of myeloid-derived suppressor cells
-
COI: 1:CAS:528:DC%2BC2cXhslCqu7bE, PID: 25164013
-
Parker KH, Sinha P, Horn LA, Clements VK, Yang H, Li J, Tracey KJ, Ostrand-Rosenberg S (2014) HMGB1 enhances immune suppression by facilitating the differentiation and suppressive activity of myeloid-derived suppressor cells. Cancer Res 74:5723–5733
-
(2014)
Cancer Res
, vol.74
, pp. 5723-5733
-
-
Parker, K.H.1
Sinha, P.2
Horn, L.A.3
Clements, V.K.4
Yang, H.5
Li, J.6
Tracey, K.J.7
Ostrand-Rosenberg, S.8
-
21
-
-
77950950894
-
Macrophage diversity enhances tumor progression and metastasis
-
COI: 1:CAS:528:DC%2BC3cXlsVSgtLc%3D, PID: 20371344
-
Qian BZ, Pollard JW (2010) Macrophage diversity enhances tumor progression and metastasis. Cell 141:39–51
-
(2010)
Cell
, vol.141
, pp. 39-51
-
-
Qian, B.Z.1
Pollard, J.W.2
-
22
-
-
84904406680
-
Tumor-associated macrophages: from mechanisms to therapy
-
COI: 1:CAS:528:DC%2BC2cXhtFOrsLvL, PID: 25035953
-
Noy R, Pollard JW (2014) Tumor-associated macrophages: from mechanisms to therapy. Immunity 41:49–61
-
(2014)
Immunity
, vol.41
, pp. 49-61
-
-
Noy, R.1
Pollard, J.W.2
-
23
-
-
84912089439
-
Macrophage IL-10 blocks CD8+ T cell-dependent responses to chemotherapy by suppressing IL-12 expression in intratumoral dendritic cells
-
COI: 1:CAS:528:DC%2BC2cXhslOrtLzK, PID: 25446896
-
Ruffell B, Chang-Strachan D, Chan V, Rosenbusch A, Ho CM, Pryer N, Daniel D, Hwang ES, Rugo HS, Coussens LM (2014) Macrophage IL-10 blocks CD8+ T cell-dependent responses to chemotherapy by suppressing IL-12 expression in intratumoral dendritic cells. Cancer Cell 26:623–637
-
(2014)
Cancer Cell
, vol.26
, pp. 623-637
-
-
Ruffell, B.1
Chang-Strachan, D.2
Chan, V.3
Rosenbusch, A.4
Ho, C.M.5
Pryer, N.6
Daniel, D.7
Hwang, E.S.8
Rugo, H.S.9
Coussens, L.M.10
-
24
-
-
84936092900
-
Intratumoral dendritic cells in the anti-tumor immune response
-
COI: 1:CAS:528:DC%2BC2MXhsFGiurfM, PID: 25597333
-
Liu Y, Cao X (2015) Intratumoral dendritic cells in the anti-tumor immune response. Cell Mol Immunol 12:387–390
-
(2015)
Cell Mol Immunol
, vol.12
, pp. 387-390
-
-
Liu, Y.1
Cao, X.2
-
25
-
-
84901215262
-
The cellular and molecular origin of tumor-associated macrophages
-
COI: 1:CAS:528:DC%2BC2cXotlWhtb0%3D, PID: 24812208
-
Franklin RA, Liao W, Sarkar A, Kim MV, Bivona MR, Liu K, Pamer EG, Li MO (2014) The cellular and molecular origin of tumor-associated macrophages. Science 344:921–925
-
(2014)
Science
, vol.344
, pp. 921-925
-
-
Franklin, R.A.1
Liao, W.2
Sarkar, A.3
Kim, M.V.4
Bivona, M.R.5
Liu, K.6
Pamer, E.G.7
Li, M.O.8
-
26
-
-
84920514940
-
The origin and function of tumor-associated macrophages
-
PID: 25220733
-
Liu Y, Cao X (2015) The origin and function of tumor-associated macrophages. Cell Mol Immunol 12:1–4
-
(2015)
Cell Mol Immunol
, vol.12
, pp. 1-4
-
-
Liu, Y.1
Cao, X.2
-
27
-
-
84896857346
-
Tumour immunology: turning macrophages on, off and on again
-
COI: 1:CAS:528:DC%2BC2cXivFyit78%3D, PID: 24566906
-
Alderton GK (2014) Tumour immunology: turning macrophages on, off and on again. Nat Rev Immunol 14:136–137
-
(2014)
Nat Rev Immunol
, vol.14
, pp. 136-137
-
-
Alderton, G.K.1
-
28
-
-
77949345555
-
Tumor-associated macrophages and survival in classic Hodgkin’s lymphoma
-
COI: 1:CAS:528:DC%2BC3cXjt1yls7Y%3D, PID: 20220182
-
Steidl C, Lee T, Shah SP, Farinha P, Han G, Nayar T, Delaney A, Jones SJ, Iqbal J, Weisenburger DD et al (2010) Tumor-associated macrophages and survival in classic Hodgkin’s lymphoma. N Engl J Med 362:875–885
-
(2010)
N Engl J Med
, vol.362
, pp. 875-885
-
-
Steidl, C.1
Lee, T.2
Shah, S.P.3
Farinha, P.4
Han, G.5
Nayar, T.6
Delaney, A.7
Jones, S.J.8
Iqbal, J.9
Weisenburger, D.D.10
-
29
-
-
84893689046
-
Human CD14+ CTLA-4+ regulatory dendritic cells suppress T-cell response by cytotoxic T-lymphocyte antigen-4-dependent IL-10 and indoleamine-2,3-dioxygenase production in hepatocellular carcinoma
-
COI: 1:CAS:528:DC%2BC2cXhslygt7s%3D, PID: 23960017
-
Han Y, Chen Z, Yang Y, Jiang Z, Gu Y, Liu Y, Lin C, Pan Z, Yu Y, Jiang M et al (2014) Human CD14+ CTLA-4+ regulatory dendritic cells suppress T-cell response by cytotoxic T-lymphocyte antigen-4-dependent IL-10 and indoleamine-2,3-dioxygenase production in hepatocellular carcinoma. Hepatology 59:567–579
-
(2014)
Hepatology
, vol.59
, pp. 567-579
-
-
Han, Y.1
Chen, Z.2
Yang, Y.3
Jiang, Z.4
Gu, Y.5
Liu, Y.6
Lin, C.7
Pan, Z.8
Yu, Y.9
Jiang, M.10
-
30
-
-
84884731613
-
Fas signal promotes the immunosuppressive function of regulatory dendritic cells via the ERK/beta-catenin pathway
-
COI: 1:CAS:528:DC%2BC3sXhsFems7zN, PID: 23943615
-
Qian C, Qian L, Yu Y, An H, Guo Z, Han Y, Chen Y, Bai Y, Wang Q, Cao X (2013) Fas signal promotes the immunosuppressive function of regulatory dendritic cells via the ERK/beta-catenin pathway. J Biol Chem 288:27825–27835
-
(2013)
J Biol Chem
, vol.288
, pp. 27825-27835
-
-
Qian, C.1
Qian, L.2
Yu, Y.3
An, H.4
Guo, Z.5
Han, Y.6
Chen, Y.7
Bai, Y.8
Wang, Q.9
Cao, X.10
-
31
-
-
84883374763
-
Apoptotic cell administration enhances pancreatic islet engraftment by induction of regulatory T cells and tolerogenic dendritic cells
-
COI: 1:CAS:528:DC%2BC3sXhsVWqsbbE, PID: 23872920
-
Wu C, Zhang Y, Jiang Y, Wang Q, Long Y, Wang C, Cao X, Chen G (2013) Apoptotic cell administration enhances pancreatic islet engraftment by induction of regulatory T cells and tolerogenic dendritic cells. Cell Mol Immunol 10:393–402
-
(2013)
Cell Mol Immunol
, vol.10
, pp. 393-402
-
-
Wu, C.1
Zhang, Y.2
Jiang, Y.3
Wang, Q.4
Long, Y.5
Wang, C.6
Cao, X.7
Chen, G.8
-
32
-
-
84941695057
-
Myeloid-derived suppressor cells in the tumor microenvironment: expect the unexpected
-
Marvel D, Gabrilovich DI (2015) Myeloid-derived suppressor cells in the tumor microenvironment: expect the unexpected. J Clin Invest DOI 10.1172/JCI80005: 1–9.
-
(2015)
J Clin Invest DOI 10.1172/JCI80005
, pp. 1-9
-
-
Marvel, D.1
Gabrilovich, D.I.2
-
33
-
-
84929414196
-
Lymphoma: immune evasion strategies
-
Upadhyay R, Hammerich L, Peng P, Brown B, Merad M, Brody JD (2015) Lymphoma: immune evasion strategies. Cancers (Basel) 7:736–762
-
(2015)
Cancers (Basel)
, vol.7
, pp. 736-762
-
-
Upadhyay, R.1
Hammerich, L.2
Peng, P.3
Brown, B.4
Merad, M.5
Brody, J.D.6
-
34
-
-
77952231121
-
Induction of lymphoidlike stroma and immune escape by tumors that express the chemokine CCL21
-
COI: 1:CAS:528:DC%2BC3cXlsFCitb4%3D, PID: 20339029
-
Shields JD, Kourtis IC, Tomei AA, Roberts JM, Swartz MA (2010) Induction of lymphoidlike stroma and immune escape by tumors that express the chemokine CCL21. Science 328:749–752
-
(2010)
Science
, vol.328
, pp. 749-752
-
-
Shields, J.D.1
Kourtis, I.C.2
Tomei, A.A.3
Roberts, J.M.4
Swartz, M.A.5
-
35
-
-
84858785703
-
Coordinated regulation of myeloid cells by tumours
-
COI: 1:CAS:528:DC%2BC38XksVensrs%3D, PID: 22437938
-
Gabrilovich DI, Ostrand-Rosenberg S, Bronte V (2012) Coordinated regulation of myeloid cells by tumours. Nat Rev Immunol 12:253–268
-
(2012)
Nat Rev Immunol
, vol.12
, pp. 253-268
-
-
Gabrilovich, D.I.1
Ostrand-Rosenberg, S.2
Bronte, V.3
-
36
-
-
84939420392
-
RORC1 regulates tumor-promoting “emergency” granulo-monocytopoiesis
-
COI: 1:CAS:528:DC%2BC2MXhtlWlsbvP, PID: 26267538
-
Strauss L, Sangaletti S, Consonni FM, Szebeni G, Morlacchi S, Totaro MG, Porta C, Anselmo A, Tartari S, Doni A et al (2015) RORC1 regulates tumor-promoting “emergency” granulo-monocytopoiesis. Cancer Cell 28:253–269
-
(2015)
Cancer Cell
, vol.28
, pp. 253-269
-
-
Strauss, L.1
Sangaletti, S.2
Consonni, F.M.3
Szebeni, G.4
Morlacchi, S.5
Totaro, M.G.6
Porta, C.7
Anselmo, A.8
Tartari, S.9
Doni, A.10
-
37
-
-
66349099293
-
Identification of a subpopulation of macrophages in mammary tumor-bearing mice that are neither M1 nor M2 and are less differentiated
-
COI: 1:CAS:528:DC%2BD1MXmsFGlu7g%3D, PID: 19458073
-
Torroella-Kouri M, Silvera R, Rodriguez D, Caso R, Shatry A, Opiela S, Ilkovitch D, Schwendener RA, Iragavarapu-Charyulu V, Cardentey Y et al (2009) Identification of a subpopulation of macrophages in mammary tumor-bearing mice that are neither M1 nor M2 and are less differentiated. Cancer Res 69:4800–4809
-
(2009)
Cancer Res
, vol.69
, pp. 4800-4809
-
-
Torroella-Kouri, M.1
Silvera, R.2
Rodriguez, D.3
Caso, R.4
Shatry, A.5
Opiela, S.6
Ilkovitch, D.7
Schwendener, R.A.8
Iragavarapu-Charyulu, V.9
Cardentey, Y.10
-
38
-
-
80054899779
-
Phenotypic and functional plasticity of cells of innate immunity: macrophages, mast cells and neutrophils
-
COI: 1:CAS:528:DC%2BC3MXhtlChtrnE, PID: 22012443
-
Galli SJ, Borregaard N, Wynn TA (2011) Phenotypic and functional plasticity of cells of innate immunity: macrophages, mast cells and neutrophils. Nat Immunol 12:1035–1044
-
(2011)
Nat Immunol
, vol.12
, pp. 1035-1044
-
-
Galli, S.J.1
Borregaard, N.2
Wynn, T.A.3
-
39
-
-
69249222379
-
Polarization of tumor-associated neutrophil phenotype by TGF-beta: “N1” versus “N2” TAN
-
COI: 1:CAS:528:DC%2BD1MXhsVChs7vN, PID: 19732719
-
Fridlender ZG, Sun J, Kim S, Kapoor V, Cheng G, Ling L, Worthen GS, Albelda SM (2009) Polarization of tumor-associated neutrophil phenotype by TGF-beta: “N1” versus “N2” TAN. Cancer Cell 16:183–194
-
(2009)
Cancer Cell
, vol.16
, pp. 183-194
-
-
Fridlender, Z.G.1
Sun, J.2
Kim, S.3
Kapoor, V.4
Cheng, G.5
Ling, L.6
Worthen, G.S.7
Albelda, S.M.8
-
40
-
-
77954951446
-
The polarization of immune cells in the tumour environment by TGFbeta
-
COI: 1:CAS:528:DC%2BC3cXosFeltbo%3D, PID: 20616810
-
Flavell RA, Sanjabi S, Wrzesinski SH, Licona-Limon P (2010) The polarization of immune cells in the tumour environment by TGFbeta. Nat Rev Immunol 10:554–567
-
(2010)
Nat Rev Immunol
, vol.10
, pp. 554-567
-
-
Flavell, R.A.1
Sanjabi, S.2
Wrzesinski, S.H.3
Licona-Limon, P.4
-
41
-
-
64849114869
-
Human dendritic cells produce TGF-beta 1 under the influence of lung carcinoma cells and prime the differentiation of CD4 + CD25 + Foxp3+ regulatory T cells
-
COI: 1:CAS:528:DC%2BD1MXitFKhtLY%3D, PID: 19234174
-
Dumitriu IE, Dunbar DR, Howie SE, Sethi T, Gregory CD (2009) Human dendritic cells produce TGF-beta 1 under the influence of lung carcinoma cells and prime the differentiation of CD4 + CD25 + Foxp3+ regulatory T cells. J Immunol 182:2795–2807
-
(2009)
J Immunol
, vol.182
, pp. 2795-2807
-
-
Dumitriu, I.E.1
Dunbar, D.R.2
Howie, S.E.3
Sethi, T.4
Gregory, C.D.5
-
42
-
-
66149118659
-
Tumor-infiltrating regulatory dendritic cells inhibit CD8+ T cell function via L-arginine metabolism
-
COI: 1:CAS:528:DC%2BD1MXjvVWitrw%3D, PID: 19293186
-
Norian LA, Rodriguez PC, O’Mara LA, Zabaleta J, Ochoa AC, Cella M, Allen PM (2009) Tumor-infiltrating regulatory dendritic cells inhibit CD8+ T cell function via L-arginine metabolism. Cancer Res 69:3086–3094
-
(2009)
Cancer Res
, vol.69
, pp. 3086-3094
-
-
Norian, L.A.1
Rodriguez, P.C.2
O’Mara, L.A.3
Zabaleta, J.4
Ochoa, A.C.5
Cella, M.6
Allen, P.M.7
-
43
-
-
84928884360
-
Id1 suppresses anti-tumour immune responses and promotes tumour progression by impairing myeloid cell maturation
-
COI: 1:CAS:528:DC%2BC2MXosFensr4%3D, PID: 25924227
-
Papaspyridonos M, Matei I, Huang Y, do Rosario Andre M, Brazier-Mitouart H, Waite JC, Chan AS, Kalter J, Ramos I, Wu Q et al (2015) Id1 suppresses anti-tumour immune responses and promotes tumour progression by impairing myeloid cell maturation. Nat Commun 6:6840
-
(2015)
Nat Commun
, vol.6
, pp. 6840
-
-
Papaspyridonos, M.1
Matei, I.2
Huang, Y.3
do Rosario Andre, M.4
Brazier-Mitouart, H.5
Waite, J.C.6
Chan, A.S.7
Kalter, J.8
Ramos, I.9
Wu, Q.10
-
44
-
-
84911886466
-
Helper T cell diversity and plasticity
-
PID: 25381803
-
Sato K (2014) Helper T cell diversity and plasticity. Circ J 78:2843–2844
-
(2014)
Circ J
, vol.78
, pp. 2843-2844
-
-
Sato, K.1
-
45
-
-
79955829822
-
The mechanisms of cancer immunoescape and development of overcoming strategies
-
PID: 21374075
-
Yaguchi T, Sumimoto H, Kudo-Saito C, Tsukamoto N, Ueda R, Iwata-Kajihara T, Nishio H, Kawamura N, Kawakami Y (2011) The mechanisms of cancer immunoescape and development of overcoming strategies. Int J Hematol 93:294–300
-
(2011)
Int J Hematol
, vol.93
, pp. 294-300
-
-
Yaguchi, T.1
Sumimoto, H.2
Kudo-Saito, C.3
Tsukamoto, N.4
Ueda, R.5
Iwata-Kajihara, T.6
Nishio, H.7
Kawamura, N.8
Kawakami, Y.9
-
46
-
-
84879604746
-
The metastasis-promoting roles of tumor-associated immune cells
-
COI: 1:CAS:528:DC%2BC3sXltFCiurs%3D
-
Smith HA, Kang Y (2013) The metastasis-promoting roles of tumor-associated immune cells. J Mol Med (Berl) 91:411–429
-
(2013)
J Mol Med (Berl)
, vol.91
, pp. 411-429
-
-
Smith, H.A.1
Kang, Y.2
-
47
-
-
84926473508
-
IL-17-producing gammadelta T cells and neutrophils conspire to promote breast cancer metastasis
-
COI: 1:CAS:528:DC%2BC2MXlsFektLg%3D, PID: 25822788
-
Coffelt SB, Kersten K, Doornebal CW, Weiden J, Vrijland K, Hau CS, Verstegen NJ, Ciampricotti M, Hawinkels LJ, Jonkers J et al (2015) IL-17-producing gammadelta T cells and neutrophils conspire to promote breast cancer metastasis. Nature 522:345–348
-
(2015)
Nature
, vol.522
, pp. 345-348
-
-
Coffelt, S.B.1
Kersten, K.2
Doornebal, C.W.3
Weiden, J.4
Vrijland, K.5
Hau, C.S.6
Verstegen, N.J.7
Ciampricotti, M.8
Hawinkels, L.J.9
Jonkers, J.10
-
48
-
-
84883745262
-
An interleukin-17-mediated paracrine network promotes tumor resistance to anti-angiogenic therapy
-
COI: 1:CAS:528:DC%2BC3sXht1Whu7nE, PID: 23913124
-
Chung AS, Wu X, Zhuang G, Ngu H, Kasman I, Zhang J, Vernes JM, Jiang Z, Meng YG, Peale FV et al (2013) An interleukin-17-mediated paracrine network promotes tumor resistance to anti-angiogenic therapy. Nat Med 19:1114–1123
-
(2013)
Nat Med
, vol.19
, pp. 1114-1123
-
-
Chung, A.S.1
Wu, X.2
Zhuang, G.3
Ngu, H.4
Kasman, I.5
Zhang, J.6
Vernes, J.M.7
Jiang, Z.8
Meng, Y.G.9
Peale, F.V.10
-
49
-
-
79956131523
-
Tumor-evoked regulatory B cells promote breast cancer metastasis by converting resting CD4(+) T cells to T-regulatory cells
-
COI: 1:CAS:528:DC%2BC3MXmtVGlt7w%3D, PID: 21444674
-
Olkhanud PB, Damdinsuren B, Bodogai M, Gress RE, Sen R, Wejksza K, Malchinkhuu E, Wersto RP, Biragyn A (2011) Tumor-evoked regulatory B cells promote breast cancer metastasis by converting resting CD4(+) T cells to T-regulatory cells. Cancer Res 71:3505–3515
-
(2011)
Cancer Res
, vol.71
, pp. 3505-3515
-
-
Olkhanud, P.B.1
Damdinsuren, B.2
Bodogai, M.3
Gress, R.E.4
Sen, R.5
Wejksza, K.6
Malchinkhuu, E.7
Wersto, R.P.8
Biragyn, A.9
-
50
-
-
79960835345
-
High FOXP3+ regulatory T-cell density in the sentinel lymph node is associated with downstream non-sentinel lymph-node metastasis in gastric cancer
-
COI: 1:CAS:528:DC%2BC3MXptlOrurw%3D, PID: 21730981
-
Lee HE, Park DJ, Kim WH, Kim HH, Lee HS (2011) High FOXP3+ regulatory T-cell density in the sentinel lymph node is associated with downstream non-sentinel lymph-node metastasis in gastric cancer. Br J Cancer 105:413–419
-
(2011)
Br J Cancer
, vol.105
, pp. 413-419
-
-
Lee, H.E.1
Park, D.J.2
Kim, W.H.3
Kim, H.H.4
Lee, H.S.5
-
51
-
-
84908635176
-
Prostanoid induces premetastatic niche in regional lymph nodes
-
COI: 1:CAS:528:DC%2BC2cXhvFSntrzM, PID: 25271626
-
Ogawa F, Amano H, Eshima K, Ito Y, Matsui Y, Hosono K, Kitasato H, Iyoda A, Iwabuchi K, Kumagai Y et al (2014) Prostanoid induces premetastatic niche in regional lymph nodes. J Clin Invest 124:4882–4894
-
(2014)
J Clin Invest
, vol.124
, pp. 4882-4894
-
-
Ogawa, F.1
Amano, H.2
Eshima, K.3
Ito, Y.4
Matsui, Y.5
Hosono, K.6
Kitasato, H.7
Iyoda, A.8
Iwabuchi, K.9
Kumagai, Y.10
-
52
-
-
84866018690
-
TGF-beta-miR-34a-CCL22 signaling-induced Treg cell recruitment promotes venous metastases of HBV-positive hepatocellular carcinoma
-
COI: 1:CAS:528:DC%2BC38XhtlCjtb%2FP, PID: 22975373
-
Yang P, Li QJ, Feng Y, Zhang Y, Markowitz GJ, Ning S, Deng Y, Zhao J, Jiang S, Yuan Y et al (2012) TGF-beta-miR-34a-CCL22 signaling-induced Treg cell recruitment promotes venous metastases of HBV-positive hepatocellular carcinoma. Cancer Cell 22:291–303
-
(2012)
Cancer Cell
, vol.22
, pp. 291-303
-
-
Yang, P.1
Li, Q.J.2
Feng, Y.3
Zhang, Y.4
Markowitz, G.J.5
Ning, S.6
Deng, Y.7
Zhao, J.8
Jiang, S.9
Yuan, Y.10
-
53
-
-
84873449312
-
Targeting galectin-1 overcomes breast cancer-associated immunosuppression and prevents metastatic disease
-
COI: 1:CAS:528:DC%2BC3sXhvV2ksb0%3D, PID: 23204230
-
Dalotto-Moreno T, Croci DO, Cerliani JP, Martinez-Allo VC, Dergan-Dylon S, Mendez-Huergo SP, Stupirski JC, Mazal D, Osinaga E, Toscano MA et al (2013) Targeting galectin-1 overcomes breast cancer-associated immunosuppression and prevents metastatic disease. Cancer Res 73:1107–1117
-
(2013)
Cancer Res
, vol.73
, pp. 1107-1117
-
-
Dalotto-Moreno, T.1
Croci, D.O.2
Cerliani, J.P.3
Martinez-Allo, V.C.4
Dergan-Dylon, S.5
Mendez-Huergo, S.P.6
Stupirski, J.C.7
Mazal, D.8
Osinaga, E.9
Toscano, M.A.10
-
54
-
-
33645286546
-
Regulatory T cells, tumour immunity and immunotherapy
-
COI: 1:CAS:528:DC%2BD28XivVyru7k%3D, PID: 16557261
-
Zou W (2006) Regulatory T cells, tumour immunity and immunotherapy. Nat Rev Immunol 6:295–307
-
(2006)
Nat Rev Immunol
, vol.6
, pp. 295-307
-
-
Zou, W.1
-
55
-
-
84867911410
-
Depletion of plasmacytoid dendritic cells inhibits tumor growth and prevents bone metastasis of breast cancer cells
-
COI: 1:CAS:528:DC%2BC38XhsFersLbJ, PID: 23018462
-
Sawant A, Hensel JA, Chanda D, Harris BA, Siegal GP, Maheshwari A, Ponnazhagan S (2012) Depletion of plasmacytoid dendritic cells inhibits tumor growth and prevents bone metastasis of breast cancer cells. J Immunol 189:4258–4265
-
(2012)
J Immunol
, vol.189
, pp. 4258-4265
-
-
Sawant, A.1
Hensel, J.A.2
Chanda, D.3
Harris, B.A.4
Siegal, G.P.5
Maheshwari, A.6
Ponnazhagan, S.7
-
56
-
-
84904676581
-
Autocrine HBEGF expression promotes breast cancer intravasation, metastasis and macrophage-independent invasion in vivo
-
COI: 1:CAS:528:DC%2BC3sXhtl2ks7fK, PID: 24013225
-
Zhou ZN, Sharma VP, Beaty BT, Roh-Johnson M, Peterson EA, Van Rooijen N, Kenny PA, Wiley HS, Condeelis JS, Segall JE (2014) Autocrine HBEGF expression promotes breast cancer intravasation, metastasis and macrophage-independent invasion in vivo. Oncogene 33:3784–3793
-
(2014)
Oncogene
, vol.33
, pp. 3784-3793
-
-
Zhou, Z.N.1
Sharma, V.P.2
Beaty, B.T.3
Roh-Johnson, M.4
Peterson, E.A.5
Van Rooijen, N.6
Kenny, P.A.7
Wiley, H.S.8
Condeelis, J.S.9
Segall, J.E.10
-
57
-
-
66149134501
-
The EGF/CSF-1 paracrine invasion loop can be triggered by heregulin beta1 and CXCL12
-
COI: 1:CAS:528:DC%2BD1MXjvVWitLY%3D, PID: 19293185
-
Hernandez L, Smirnova T, Kedrin D, Wyckoff J, Zhu L, Stanley ER, Cox D, Muller WJ, Pollard JW, Van Rooijen N et al (2009) The EGF/CSF-1 paracrine invasion loop can be triggered by heregulin beta1 and CXCL12. Cancer Res 69:3221–3227
-
(2009)
Cancer Res
, vol.69
, pp. 3221-3227
-
-
Hernandez, L.1
Smirnova, T.2
Kedrin, D.3
Wyckoff, J.4
Zhu, L.5
Stanley, E.R.6
Cox, D.7
Muller, W.J.8
Pollard, J.W.9
Van Rooijen, N.10
-
58
-
-
80054686286
-
Tumor metastasis: molecular insights and evolving paradigms
-
COI: 1:CAS:528:DC%2BC3MXhtlaksb3N, PID: 22000009
-
Valastyan S, Weinberg RA (2011) Tumor metastasis: molecular insights and evolving paradigms. Cell 147:275–292
-
(2011)
Cell
, vol.147
, pp. 275-292
-
-
Valastyan, S.1
Weinberg, R.A.2
-
59
-
-
84892686102
-
Doxorubicin eliminates myeloid-derived suppressor cells and enhances the efficacy of adoptive T-cell transfer in breast cancer
-
COI: 1:CAS:528:DC%2BC2cXislGrsw%3D%3D, PID: 24197130
-
Alizadeh D, Trad M, Hanke NT, Larmonier CB, Janikashvili N, Bonnotte B, Katsanis E, Larmonier N (2014) Doxorubicin eliminates myeloid-derived suppressor cells and enhances the efficacy of adoptive T-cell transfer in breast cancer. Cancer Res 74:104–118
-
(2014)
Cancer Res
, vol.74
, pp. 104-118
-
-
Alizadeh, D.1
Trad, M.2
Hanke, N.T.3
Larmonier, C.B.4
Janikashvili, N.5
Bonnotte, B.6
Katsanis, E.7
Larmonier, N.8
-
60
-
-
67651160649
-
CD4(+) T cells regulate pulmonary metastasis of mammary carcinomas by enhancing protumor properties of macrophages
-
COI: 1:CAS:528:DC%2BD1MXhsVCjsrfJ, PID: 19647220
-
DeNardo DG, Barreto JB, Andreu P, Vasquez L, Tawfik D, Kolhatkar N, Coussens LM (2009) CD4(+) T cells regulate pulmonary metastasis of mammary carcinomas by enhancing protumor properties of macrophages. Cancer Cell 16:91–102
-
(2009)
Cancer Cell
, vol.16
, pp. 91-102
-
-
DeNardo, D.G.1
Barreto, J.B.2
Andreu, P.3
Vasquez, L.4
Tawfik, D.5
Kolhatkar, N.6
Coussens, L.M.7
-
61
-
-
84899051828
-
JAK/STAT3 signaling is required for TGF-beta-induced epithelial-mesenchymal transition in lung cancer cells
-
COI: 1:CAS:528:DC%2BC2cXptlykt7o%3D, PID: 24573038
-
Liu RY, Zeng Y, Lei Z, Wang L, Yang H, Liu Z, Zhao J, Zhang HT (2014) JAK/STAT3 signaling is required for TGF-beta-induced epithelial-mesenchymal transition in lung cancer cells. Int J Oncol 44:1643–1651
-
(2014)
Int J Oncol
, vol.44
, pp. 1643-1651
-
-
Liu, R.Y.1
Zeng, Y.2
Lei, Z.3
Wang, L.4
Yang, H.5
Liu, Z.6
Zhao, J.7
Zhang, H.T.8
-
62
-
-
79953750307
-
Targeting the ANG2/TIE2 axis inhibits tumor growth and metastasis by impairing angiogenesis and disabling rebounds of proangiogenic myeloid cells
-
COI: 1:CAS:528:DC%2BC3MXks1Wqsb0%3D, PID: 21481792
-
Mazzieri R, Pucci F, Moi D, Zonari E, Ranghetti A, Berti A, Politi LS, Gentner B, Brown JL, Naldini L et al (2011) Targeting the ANG2/TIE2 axis inhibits tumor growth and metastasis by impairing angiogenesis and disabling rebounds of proangiogenic myeloid cells. Cancer Cell 19:512–526
-
(2011)
Cancer Cell
, vol.19
, pp. 512-526
-
-
Mazzieri, R.1
Pucci, F.2
Moi, D.3
Zonari, E.4
Ranghetti, A.5
Berti, A.6
Politi, L.S.7
Gentner, B.8
Brown, J.L.9
Naldini, L.10
-
63
-
-
0035164478
-
Increased production of immature myeloid cells in cancer patients: a mechanism of immunosuppression in cancer
-
COI: 1:CAS:528:DC%2BD3MXis1elsw%3D%3D, PID: 11123353
-
Almand B, Clark JI, Nikitina E, van Beynen J, English NR, Knight SC, Carbone DP, Gabrilovich DI (2001) Increased production of immature myeloid cells in cancer patients: a mechanism of immunosuppression in cancer. J Immunol 166:678–689
-
(2001)
J Immunol
, vol.166
, pp. 678-689
-
-
Almand, B.1
Clark, J.I.2
Nikitina, E.3
van Beynen, J.4
English, N.R.5
Knight, S.C.6
Carbone, D.P.7
Gabrilovich, D.I.8
-
64
-
-
54849440346
-
Increased circulating myeloid-derived suppressor cells correlate with clinical cancer stage, metastatic tumor burden, and doxorubicin-cyclophosphamide chemotherapy
-
COI: 1:CAS:528:DC%2BD1cXht1yqs7bN, PID: 18446337
-
Diaz-Montero CM, Salem ML, Nishimura MI, Garrett-Mayer E, Cole DJ, Montero AJ (2009) Increased circulating myeloid-derived suppressor cells correlate with clinical cancer stage, metastatic tumor burden, and doxorubicin-cyclophosphamide chemotherapy. Cancer Immunol Immunother 58:49–59
-
(2009)
Cancer Immunol Immunother
, vol.58
, pp. 49-59
-
-
Diaz-Montero, C.M.1
Salem, M.L.2
Nishimura, M.I.3
Garrett-Mayer, E.4
Cole, D.J.5
Montero, A.J.6
-
65
-
-
34247261531
-
Quantification of regulatory T cells enables the identification of high-risk breast cancer patients and those at risk of late relapse
-
PID: 17135638
-
Bates GJ, Fox SB, Han C, Leek RD, Garcia JF, Harris AL, Banham AH (2006) Quantification of regulatory T cells enables the identification of high-risk breast cancer patients and those at risk of late relapse. J Clin Oncol 24:5373–5380
-
(2006)
J Clin Oncol
, vol.24
, pp. 5373-5380
-
-
Bates, G.J.1
Fox, S.B.2
Han, C.3
Leek, R.D.4
Garcia, J.F.5
Harris, A.L.6
Banham, A.H.7
-
66
-
-
84903997593
-
Combination of cancer immunotherapy with clinically available drugs that can block immunosuppressive cells
-
COI: 1:CAS:528:DC%2BC2cXhtFeltbnL, PID: 24295450
-
Kim SJ, Ha GH, Kim SH, Kang CD (2014) Combination of cancer immunotherapy with clinically available drugs that can block immunosuppressive cells. Immunol Invest 43:517–534
-
(2014)
Immunol Invest
, vol.43
, pp. 517-534
-
-
Kim, S.J.1
Ha, G.H.2
Kim, S.H.3
Kang, C.D.4
-
67
-
-
84937072222
-
Lymphocyte activation gene-3 (LAG-3, CD223) in plasmacytoid dendritic cells (pDCs): a molecular target for the restoration of active antitumor immunity
-
PID: 25941596
-
Castelli C, Triebel F, Rivoltini L, Camisaschi C (2014) Lymphocyte activation gene-3 (LAG-3, CD223) in plasmacytoid dendritic cells (pDCs): a molecular target for the restoration of active antitumor immunity. Oncoimmunology 3, e967146
-
(2014)
Oncoimmunology
, vol.3
-
-
Castelli, C.1
Triebel, F.2
Rivoltini, L.3
Camisaschi, C.4
-
68
-
-
84862865552
-
LAG-3 in cancer immunotherapy
-
COI: 1:CAS:528:DC%2BC3MXotFWksrs%3D, PID: 21086108
-
Goldberg MV, Drake CG (2011) LAG-3 in cancer immunotherapy. Curr Top Microbiol Immunol 344:269–278
-
(2011)
Curr Top Microbiol Immunol
, vol.344
, pp. 269-278
-
-
Goldberg, M.V.1
Drake, C.G.2
-
69
-
-
84945449684
-
Dysfunction of PSA-specific CD8 T cells in prostate cancer patients correlates with CD38 and Tim-3 expression
-
Japp AS, Kursunel MA, Meier S, Malzer JN, Li X, Rahman NA, Jekabsons W, Krause H, Magheli A, Klopf C et al. (2015) Dysfunction of PSA-specific CD8 T cells in prostate cancer patients correlates with CD38 and Tim-3 expression. Cancer Immunol Immunother DOI 10.1007/s00262-015-1752-y
-
(2015)
Cancer Immunol Immunother DOI 10.1007/s00262-015-1752-y
-
-
Japp, A.S.1
Kursunel, M.A.2
Meier, S.3
Malzer, J.N.4
Li, X.5
Rahman, N.A.6
Jekabsons, W.7
Krause, H.8
Magheli, A.9
Klopf, C.10
-
70
-
-
84897429090
-
VISTA regulates the development of protective antitumor immunity
-
PID: 24691994
-
Le Mercier I, Chen W, Lines JL, Day M, Li J, Sergent P, Noelle RJ, Wang L (2014) VISTA regulates the development of protective antitumor immunity. Cancer Res 74:1933–1944
-
(2014)
Cancer Res
, vol.74
, pp. 1933-1944
-
-
Le Mercier, I.1
Chen, W.2
Lines, J.L.3
Day, M.4
Li, J.5
Sergent, P.6
Noelle, R.J.7
Wang, L.8
-
71
-
-
84886895500
-
The co-receptor BTLA negatively regulates human Vgamma9Vdelta2 T-cell proliferation: a potential way of immune escape for lymphoma cells
-
COI: 1:CAS:528:DC%2BC3sXhtlWltLbE, PID: 23692853
-
Gertner-Dardenne J, Fauriat C, Orlanducci F, Thibult ML, Pastor S, Fitzgibbon J, Bouabdallah R, Xerri L, Olive D (2013) The co-receptor BTLA negatively regulates human Vgamma9Vdelta2 T-cell proliferation: a potential way of immune escape for lymphoma cells. Blood 122:922–931
-
(2013)
Blood
, vol.122
, pp. 922-931
-
-
Gertner-Dardenne, J.1
Fauriat, C.2
Orlanducci, F.3
Thibult, M.L.4
Pastor, S.5
Fitzgibbon, J.6
Bouabdallah, R.7
Xerri, L.8
Olive, D.9
-
72
-
-
84928774156
-
The future of immune checkpoint therapy
-
COI: 1:CAS:528:DC%2BC2MXls1Wmurg%3D, PID: 25838373
-
Sharma P, Allison JP (2015) The future of immune checkpoint therapy. Science 348:56–61
-
(2015)
Science
, vol.348
, pp. 56-61
-
-
Sharma, P.1
Allison, J.P.2
-
73
-
-
33646794392
-
Checkpoint blockade in cancer immunotherapy
-
COI: 1:CAS:528:DC%2BD1cXhsVCju74%3D, PID: 16730267
-
Korman AJ, Peggs KS, Allison JP (2006) Checkpoint blockade in cancer immunotherapy. Adv Immunol 90:297–339
-
(2006)
Adv Immunol
, vol.90
, pp. 297-339
-
-
Korman, A.J.1
Peggs, K.S.2
Allison, J.P.3
-
74
-
-
84936791837
-
Nivolumab versus docetaxel in advanced squamous-cell non-small-cell lung cancer
-
COI: 1:CAS:528:DC%2BC2MXht12qu7%2FJ, PID: 26028407
-
Brahmer J, Reckamp KL, Baas P, Crino L, Eberhardt WE, Poddubskaya E, Antonia S, Pluzanski A, Vokes EE, Holgado E et al (2015) Nivolumab versus docetaxel in advanced squamous-cell non-small-cell lung cancer. N Engl J Med 373:123–135
-
(2015)
N Engl J Med
, vol.373
, pp. 123-135
-
-
Brahmer, J.1
Reckamp, K.L.2
Baas, P.3
Crino, L.4
Eberhardt, W.E.5
Poddubskaya, E.6
Antonia, S.7
Pluzanski, A.8
Vokes, E.E.9
Holgado, E.10
-
75
-
-
77954801079
-
Improved survival with ipilimumab in patients with metastatic melanoma
-
COI: 1:CAS:528:DC%2BC3cXhtVCrtrbN, PID: 20525992
-
Hodi FS, O’Day SJ, McDermott DF, Weber RW, Sosman JA, Haanen JB, Gonzalez R, Robert C, Schadendorf D, Hassel JC et al (2010) Improved survival with ipilimumab in patients with metastatic melanoma. N Engl J Med 363:711–723
-
(2010)
N Engl J Med
, vol.363
, pp. 711-723
-
-
Hodi, F.S.1
O’Day, S.J.2
McDermott, D.F.3
Weber, R.W.4
Sosman, J.A.5
Haanen, J.B.6
Gonzalez, R.7
Robert, C.8
Schadendorf, D.9
Hassel, J.C.10
-
76
-
-
84879777241
-
Nivolumab plus ipilimumab in advanced melanoma
-
COI: 1:CAS:528:DC%2BC3sXht1ektbrF, PID: 23724867
-
Wolchok JD, Kluger H, Callahan MK, Postow MA, Rizvi NA, Lesokhin AM, Segal NH, Ariyan CE, Gordon RA, Reed K et al (2013) Nivolumab plus ipilimumab in advanced melanoma. N Engl J Med 369:122–133
-
(2013)
N Engl J Med
, vol.369
, pp. 122-133
-
-
Wolchok, J.D.1
Kluger, H.2
Callahan, M.K.3
Postow, M.A.4
Rizvi, N.A.5
Lesokhin, A.M.6
Segal, N.H.7
Ariyan, C.E.8
Gordon, R.A.9
Reed, K.10
-
77
-
-
84862859820
-
Safety, activity, and immune correlates of anti-PD-1 antibody in cancer
-
COI: 1:CAS:528:DC%2BC38XhtV2rs7fN, PID: 22658127
-
Topalian SL, Hodi FS, Brahmer JR, Gettinger SN, Smith DC, McDermott DF, Powderly JD, Carvajal RD, Sosman JA, Atkins MB et al (2012) Safety, activity, and immune correlates of anti-PD-1 antibody in cancer. N Engl J Med 366:2443–2454
-
(2012)
N Engl J Med
, vol.366
, pp. 2443-2454
-
-
Topalian, S.L.1
Hodi, F.S.2
Brahmer, J.R.3
Gettinger, S.N.4
Smith, D.C.5
McDermott, D.F.6
Powderly, J.D.7
Carvajal, R.D.8
Sosman, J.A.9
Atkins, M.B.10
-
78
-
-
84941280057
-
Beyond CTLA-4 and PD-1, the generation Z of negative checkpoint regulators
-
PID: 26347741
-
Le Mercier I, Lines JL, Noelle RJ (2015) Beyond CTLA-4 and PD-1, the generation Z of negative checkpoint regulators. Front Immunol 6:418
-
(2015)
Front Immunol
, vol.6
, pp. 418
-
-
Le Mercier, I.1
Lines, J.L.2
Noelle, R.J.3
-
79
-
-
79955977180
-
Coexpression of Tim-3 and PD-1 identifies a CD8+ T-cell exhaustion phenotype in mice with disseminated acute myelogenous leukemia
-
COI: 1:CAS:528:DC%2BC3MXlvFKlsro%3D, PID: 21385853
-
Zhou Q, Munger ME, Veenstra RG, Weigel BJ, Hirashima M, Munn DH, Murphy WJ, Azuma M, Anderson AC, Kuchroo VK et al (2011) Coexpression of Tim-3 and PD-1 identifies a CD8+ T-cell exhaustion phenotype in mice with disseminated acute myelogenous leukemia. Blood 117:4501–4510
-
(2011)
Blood
, vol.117
, pp. 4501-4510
-
-
Zhou, Q.1
Munger, M.E.2
Veenstra, R.G.3
Weigel, B.J.4
Hirashima, M.5
Munn, D.H.6
Murphy, W.J.7
Azuma, M.8
Anderson, A.C.9
Kuchroo, V.K.10
-
80
-
-
84885716979
-
TIM3FOXP3 regulatory T cells are tissue-specific promoters of T-cell dysfunction in cancer
-
PID: 23734331
-
Sakuishi K, Ngiow SF, Sullivan JM, Teng MW, Kuchroo VK, Smyth MJ, Anderson AC (2013) TIM3FOXP3 regulatory T cells are tissue-specific promoters of T-cell dysfunction in cancer. Oncoimmunology 2, e23849
-
(2013)
Oncoimmunology
, vol.2
-
-
Sakuishi, K.1
Ngiow, S.F.2
Sullivan, J.M.3
Teng, M.W.4
Kuchroo, V.K.5
Smyth, M.J.6
Anderson, A.C.7
-
81
-
-
74949125667
-
BTLA mediates inhibition of human tumor-specific CD8+ T cells that can be partially reversed by vaccination
-
COI: 1:CAS:528:DC%2BC3cXislWnuw%3D%3D, PID: 20038811
-
Derre L, Rivals JP, Jandus C, Pastor S, Rimoldi D, Romero P, Michielin O, Olive D, Speiser DE (2010) BTLA mediates inhibition of human tumor-specific CD8+ T cells that can be partially reversed by vaccination. J Clin Invest 120:157–167
-
(2010)
J Clin Invest
, vol.120
, pp. 157-167
-
-
Derre, L.1
Rivals, J.P.2
Jandus, C.3
Pastor, S.4
Rimoldi, D.5
Romero, P.6
Michielin, O.7
Olive, D.8
Speiser, D.E.9
-
82
-
-
84863115998
-
Immune inhibitory molecules LAG-3 and PD-1 synergistically regulate T-cell function to promote tumoral immune escape
-
COI: 1:CAS:528:DC%2BC38XitlGit7k%3D, PID: 22186141
-
Woo SRTM, Goldberg MV, Bankoti J, Selby M, Nirschl CJ, Bettini ML, Gravano DM, Vogel P, Liu CL, Tangsombatvisit S et al (2012) Immune inhibitory molecules LAG-3 and PD-1 synergistically regulate T-cell function to promote tumoral immune escape. Cancer Res 72:917–927
-
(2012)
Cancer Res
, vol.72
, pp. 917-927
-
-
Woo, S.R.T.M.1
Goldberg, M.V.2
Bankoti, J.3
Selby, M.4
Nirschl, C.J.5
Bettini, M.L.6
Gravano, D.M.7
Vogel, P.8
Liu, C.L.9
Tangsombatvisit, S.10
-
83
-
-
84902129552
-
Generation of a new therapeutic peptide that depletes myeloid-derived suppressor cells in tumor-bearing mice
-
COI: 1:CAS:528:DC%2BC2cXos1eqsLc%3D, PID: 24859530
-
Qin H, Lerman B, Sakamaki I, Wei G, Cha SC, Rao SS, Qian J, Hailemichael Y, Nurieva R, Dwyer KC et al (2014) Generation of a new therapeutic peptide that depletes myeloid-derived suppressor cells in tumor-bearing mice. Nat Med 20:676–681
-
(2014)
Nat Med
, vol.20
, pp. 676-681
-
-
Qin, H.1
Lerman, B.2
Sakamaki, I.3
Wei, G.4
Cha, S.C.5
Rao, S.S.6
Qian, J.7
Hailemichael, Y.8
Nurieva, R.9
Dwyer, K.C.10
-
84
-
-
84903188335
-
Inactivation of PI(3)K p110delta breaks regulatory T-cell-mediated immune tolerance to cancer
-
COI: 1:CAS:528:DC%2BC2cXpslGhs7s%3D, PID: 24919154
-
Ali K, Soond DR, Pineiro R, Hagemann T, Pearce W, Lim EL, Bouabe H, Scudamore CL, Hancox T, Maecker H et al (2014) Inactivation of PI(3)K p110delta breaks regulatory T-cell-mediated immune tolerance to cancer. Nature 510:407–411
-
(2014)
Nature
, vol.510
, pp. 407-411
-
-
Ali, K.1
Soond, D.R.2
Pineiro, R.3
Hagemann, T.4
Pearce, W.5
Lim, E.L.6
Bouabe, H.7
Scudamore, C.L.8
Hancox, T.9
Maecker, H.10
-
85
-
-
84905366154
-
Immunotherapy: PI3Kdelta inhibition lifts the breaks on antitumour immunity
-
PID: 24981255
-
Killock D (2014) Immunotherapy: PI3Kdelta inhibition lifts the breaks on antitumour immunity. Nat Rev Clin Oncol 11:442
-
(2014)
Nat Rev Clin Oncol
, vol.11
, pp. 442
-
-
Killock, D.1
-
86
-
-
84924292037
-
Human regulatory T cells lack the cyclophosphamide-extruding transporter ABCB1 and are more susceptible to cyclophosphamide-induced apoptosis
-
COI: 1:CAS:528:DC%2BC2MXlt1GhtL4%3D, PID: 25251877
-
Dimeloe S, Frick C, Fischer M, Gubser PM, Razik L, Bantug GR, Ravon M, Langenkamp A, Hess C (2014) Human regulatory T cells lack the cyclophosphamide-extruding transporter ABCB1 and are more susceptible to cyclophosphamide-induced apoptosis. Eur J Immunol 44:3614–3620
-
(2014)
Eur J Immunol
, vol.44
, pp. 3614-3620
-
-
Dimeloe, S.1
Frick, C.2
Fischer, M.3
Gubser, P.M.4
Razik, L.5
Bantug, G.R.6
Ravon, M.7
Langenkamp, A.8
Hess, C.9
-
87
-
-
84944454410
-
Depletion of regulatory T cells by targeting CC chemokine receptor type 4 with mogamulizumab
-
PID: 26140234
-
Ni X, Langridge T, Duvic M (2015) Depletion of regulatory T cells by targeting CC chemokine receptor type 4 with mogamulizumab. Oncoimmunology 4, e1011524
-
(2015)
Oncoimmunology
, vol.4
-
-
Ni, X.1
Langridge, T.2
Duvic, M.3
-
88
-
-
84926525215
-
Radiation and dual checkpoint blockade activate non-redundant immune mechanisms in cancer
-
COI: 1:CAS:528:DC%2BC2MXktVCnsbw%3D, PID: 25754329
-
Twyman-Saint Victor C, Rech AJ, Maity A, Rengan R, Pauken KE, Stelekati E, Benci JL, Xu B, Dada H, Odorizzi PM et al (2015) Radiation and dual checkpoint blockade activate non-redundant immune mechanisms in cancer. Nature 520:373–377
-
(2015)
Nature
, vol.520
, pp. 373-377
-
-
Twyman-Saint Victor, C.1
Rech, A.J.2
Maity, A.3
Rengan, R.4
Pauken, K.E.5
Stelekati, E.6
Benci, J.L.7
Xu, B.8
Dada, H.9
Odorizzi, P.M.10
-
89
-
-
84861175955
-
CD25 blockade depletes and selectively reprograms regulatory T cells in concert with immunotherapy in cancer patients
-
Rech AJ, Mick R, Martin S, Recio A, Aqui NA, Powell DJ Jr, Colligon TA, Trosko JA, Leinbach LI, Pletcher CH et al (2012) CD25 blockade depletes and selectively reprograms regulatory T cells in concert with immunotherapy in cancer patients. Sci Transl Med 4:134ra162
-
(2012)
Sci Transl Med
, vol.4
, pp. 134162
-
-
Rech, A.J.1
Mick, R.2
Martin, S.3
Recio, A.4
Aqui, N.A.5
Powell, D.J.6
Colligon, T.A.7
Trosko, J.A.8
Leinbach, L.I.9
Pletcher, C.H.10
-
90
-
-
84876424760
-
Macrophage regulation of tumor responses to anticancer therapies
-
PID: 23518347
-
De Palma M, Lewis CE (2013) Macrophage regulation of tumor responses to anticancer therapies. Cancer Cell 23:277–286
-
(2013)
Cancer Cell
, vol.23
, pp. 277-286
-
-
De Palma, M.1
Lewis, C.E.2
-
91
-
-
84882619034
-
Targeting the tumor microenvironment: from understanding pathways to effective clinical trials
-
COI: 1:CAS:528:DC%2BC3sXht1OisrbN, PID: 23913938
-
Fang H, Declerck YA (2013) Targeting the tumor microenvironment: from understanding pathways to effective clinical trials. Cancer Res 73:4965–4977
-
(2013)
Cancer Res
, vol.73
, pp. 4965-4977
-
-
Fang, H.1
Declerck, Y.A.2
-
92
-
-
84858758766
-
Adoptive immunotherapy for cancer: harnessing the T cell response
-
COI: 1:CAS:528:DC%2BC38XksVeht7s%3D, PID: 22437939
-
Restifo NP, Dudley ME, Rosenberg SA (2012) Adoptive immunotherapy for cancer: harnessing the T cell response. Nat Rev Immunol 12:269–281
-
(2012)
Nat Rev Immunol
, vol.12
, pp. 269-281
-
-
Restifo, N.P.1
Dudley, M.E.2
Rosenberg, S.A.3
-
93
-
-
84858760109
-
Combining immunotherapy and targeted therapies in cancer treatment
-
COI: 1:CAS:528:DC%2BC38XksVehtrg%3D, PID: 22437869
-
Vanneman M, Dranoff G (2012) Combining immunotherapy and targeted therapies in cancer treatment. Nat Rev Cancer 12:237–251
-
(2012)
Nat Rev Cancer
, vol.12
, pp. 237-251
-
-
Vanneman, M.1
Dranoff, G.2
-
94
-
-
84915793974
-
Cessation of CCL2 inhibition accelerates breast cancer metastasis by promoting angiogenesis
-
COI: 1:CAS:528:DC%2BC2cXhvVemtr3E, PID: 25337873
-
Bonapace L, Coissieux MM, Wyckoff J, Mertz KD, Varga Z, Junt T, Bentires-Alj M (2014) Cessation of CCL2 inhibition accelerates breast cancer metastasis by promoting angiogenesis. Nature 515:130–133
-
(2014)
Nature
, vol.515
, pp. 130-133
-
-
Bonapace, L.1
Coissieux, M.M.2
Wyckoff, J.3
Mertz, K.D.4
Varga, Z.5
Junt, T.6
Bentires-Alj, M.7
-
95
-
-
79960411324
-
CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis
-
COI: 1:CAS:528:DC%2BC3MXntFKrsb0%3D, PID: 21654748
-
Qian BZ, Li J, Zhang H, Kitamura T, Zhang J, Campion LR, Kaiser EA, Snyder LA, Pollard JW (2011) CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis. Nature 475:222–225
-
(2011)
Nature
, vol.475
, pp. 222-225
-
-
Qian, B.Z.1
Li, J.2
Zhang, H.3
Kitamura, T.4
Zhang, J.5
Campion, L.R.6
Kaiser, E.A.7
Snyder, L.A.8
Pollard, J.W.9
-
96
-
-
84936953099
-
Melanoma-intrinsic beta-catenin signalling prevents anti-tumour immunity
-
COI: 1:CAS:528:DC%2BC2MXhtFaitrrL, PID: 25970248
-
Spranger S, Bao R, Gajewski TF (2015) Melanoma-intrinsic beta-catenin signalling prevents anti-tumour immunity. Nature 523:231–235
-
(2015)
Nature
, vol.523
, pp. 231-235
-
-
Spranger, S.1
Bao, R.2
Gajewski, T.F.3
-
97
-
-
84902137525
-
Targeting CD137 enhances the efficacy of cetuximab
-
COI: 1:CAS:528:DC%2BC2cXpvFahsrc%3D, PID: 24837434
-
Kohrt HE, Colevas AD, Houot R, Weiskopf K, Goldstein MJ, Lund P, Mueller A, Sagiv-Barfi I, Marabelle A, Lira R et al (2014) Targeting CD137 enhances the efficacy of cetuximab. J Clin Invest 124:2668–2682
-
(2014)
J Clin Invest
, vol.124
, pp. 2668-2682
-
-
Kohrt, H.E.1
Colevas, A.D.2
Houot, R.3
Weiskopf, K.4
Goldstein, M.J.5
Lund, P.6
Mueller, A.7
Sagiv-Barfi, I.8
Marabelle, A.9
Lira, R.10
|