-
1
-
-
84923197441
-
Uncoupling lipid metabolism from inflammation through fatty acid binding protein-dependent expression of UCP2
-
Xu H., Hertzel A.V., Steen K.A., Wang Q., Suttles J., Bernlohr D.A. Uncoupling lipid metabolism from inflammation through fatty acid binding protein-dependent expression of UCP2. Mol. Cell. Biol. 2015, 35:1055-1065. 10.1128/MCB.01122-14.
-
(2015)
Mol. Cell. Biol.
, vol.35
, pp. 1055-1065
-
-
Xu, H.1
Hertzel, A.V.2
Steen, K.A.3
Wang, Q.4
Suttles, J.5
Bernlohr, D.A.6
-
2
-
-
5644231992
-
Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes
-
Ozcan U., Cao Q., Yilmaz E., Lee A.-H., Iwakoshi N.N., Ozdelen E., et al. Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes. Science 2004, 306:457-461. 10.1126/science.1103160.
-
(2004)
Science
, vol.306
, pp. 457-461
-
-
Ozcan, U.1
Cao, Q.2
Yilmaz, E.3
Lee, A.-H.4
Iwakoshi, N.N.5
Ozdelen, E.6
-
3
-
-
84864320585
-
New insights into ER stress-induced insulin resistance
-
Flamment M., Hajduch E., Ferré P., Foufelle F. New insights into ER stress-induced insulin resistance. Trends Endocrinol. Metab. 2012, 23:381-390. 10.1016/j.tem.2012.06.003.
-
(2012)
Trends Endocrinol. Metab.
, vol.23
, pp. 381-390
-
-
Flamment, M.1
Hajduch, E.2
Ferré, P.3
Foufelle, F.4
-
4
-
-
50449086746
-
Obesity and free fatty acids
-
viii-ix
-
Boden G. Obesity and free fatty acids. Endocrinol. Metab. Clin. N. Am. 2008, 37:635-646. viii-ix. 10.1016/j.ecl.2008.06.007.
-
(2008)
Endocrinol. Metab. Clin. N. Am.
, vol.37
, pp. 635-646
-
-
Boden, G.1
-
6
-
-
84855396644
-
Palmitic and linoleic acids induce ER stress and apoptosis in hepatoma cells
-
Zhang Y., Xue R., Zhang Z., Yang X., Shi H. Palmitic and linoleic acids induce ER stress and apoptosis in hepatoma cells. Lipids Health Dis. 2012, 11:1. 10.1186/1476-511X-11-1.
-
(2012)
Lipids Health Dis.
, vol.11
, pp. 1
-
-
Zhang, Y.1
Xue, R.2
Zhang, Z.3
Yang, X.4
Shi, H.5
-
7
-
-
84867795111
-
Palmitate causes endoplasmic reticulum stress and apoptosis in human mesenchymal stem cells: prevention by AMPK activator
-
Lu J., Wang Q., Huang L., Dong H., Lin L., Lin N., et al. Palmitate causes endoplasmic reticulum stress and apoptosis in human mesenchymal stem cells: prevention by AMPK activator. Endocrinology 2012, 153:5275-5284. 10.1210/en.2012-1418.
-
(2012)
Endocrinology
, vol.153
, pp. 5275-5284
-
-
Lu, J.1
Wang, Q.2
Huang, L.3
Dong, H.4
Lin, L.5
Lin, N.6
-
8
-
-
33745828301
-
Saturated fatty acids induce endoplasmic reticulum stress and apoptosis independently of ceramide in liver cells
-
Wei Y., Wang D., Topczewski F., Pagliassotti M.J. Saturated fatty acids induce endoplasmic reticulum stress and apoptosis independently of ceramide in liver cells. Am. J. Physiol. Endocrinol. Metab. 2006, 291:E275-E281. 10.1152/ajpendo.00644.2005.
-
(2006)
Am. J. Physiol. Endocrinol. Metab.
, vol.291
, pp. E275-E281
-
-
Wei, Y.1
Wang, D.2
Topczewski, F.3
Pagliassotti, M.J.4
-
9
-
-
84875151418
-
Free fatty acid induces endoplasmic reticulum stress and apoptosis of β-cells by Ca2+/calpain-2 pathways
-
Cui W., Ma J., Wang X., Yang W., Zhang J., Ji Q. Free fatty acid induces endoplasmic reticulum stress and apoptosis of β-cells by Ca2+/calpain-2 pathways. PLoS One 2013, 8:e59921. 10.1371/journal.pone.0059921.
-
(2013)
PLoS One
, vol.8
, pp. e59921
-
-
Cui, W.1
Ma, J.2
Wang, X.3
Yang, W.4
Zhang, J.5
Ji, Q.6
-
10
-
-
84883387793
-
Targeting the unfolded protein response in disease
-
Hetz C., Chevet E., Harding H.P. Targeting the unfolded protein response in disease. Nat. Rev. Drug Discov. 2013, 12:703-719. 10.1038/nrd3976.
-
(2013)
Nat. Rev. Drug Discov.
, vol.12
, pp. 703-719
-
-
Hetz, C.1
Chevet, E.2
Harding, H.P.3
-
11
-
-
71549152580
-
Reducing endoplasmic reticulum stress through a macrophage lipid chaperone alleviates atherosclerosis
-
Erbay E., Babaev V.R., Mayers J.R., Makowski L., Charles K.N., Snitow M.E., et al. Reducing endoplasmic reticulum stress through a macrophage lipid chaperone alleviates atherosclerosis. Nat. Med. 2009, 15:1383-1391. 10.1038/nm.2067.
-
(2009)
Nat. Med.
, vol.15
, pp. 1383-1391
-
-
Erbay, E.1
Babaev, V.R.2
Mayers, J.R.3
Makowski, L.4
Charles, K.N.5
Snitow, M.E.6
-
12
-
-
79952708723
-
Endoplasmic reticulum stress in liver disease
-
Malhi H., Kaufman R.J. Endoplasmic reticulum stress in liver disease. J. Hepatol. 2011, 54:795-809. 10.1016/j.jhep.2010.11.005.
-
(2011)
J. Hepatol.
, vol.54
, pp. 795-809
-
-
Malhi, H.1
Kaufman, R.J.2
-
13
-
-
44449118921
-
Fatty acid-binding proteins: role in metabolic diseases and potential as drug targets
-
Furuhashi M., Hotamisligil G.S. Fatty acid-binding proteins: role in metabolic diseases and potential as drug targets. Nat. Rev. Drug Discov. 2008, 7:489-503. 10.1038/nrd2589.
-
(2008)
Nat. Rev. Drug Discov.
, vol.7
, pp. 489-503
-
-
Furuhashi, M.1
Hotamisligil, G.S.2
-
14
-
-
33644545704
-
Adipocyte fatty acid-binding protein is a plasma biomarker closely associated with obesity and metabolic syndrome
-
Xu A., Wang Y., Xu J.Y., Stejskal D., Tam S., Zhang J., et al. Adipocyte fatty acid-binding protein is a plasma biomarker closely associated with obesity and metabolic syndrome. Clin. Chem. 2006, 52:405-413. 10.1373/clinchem.2005.062463.
-
(2006)
Clin. Chem.
, vol.52
, pp. 405-413
-
-
Xu, A.1
Wang, Y.2
Xu, J.Y.3
Stejskal, D.4
Tam, S.5
Zhang, J.6
-
15
-
-
77951082173
-
FABP4 plasma levels are increased in familial combined hyperlipidemia
-
Cabré A., Lázaro I., Cofán M., Jarauta E., Plana N., Garcia-Otín A.L., et al. FABP4 plasma levels are increased in familial combined hyperlipidemia. J. Lipid Res. 2010, 51:1173-1178. 10.1194/jlr.M900066.
-
(2010)
J. Lipid Res.
, vol.51
, pp. 1173-1178
-
-
Cabré, A.1
Lázaro, I.2
Cofán, M.3
Jarauta, E.4
Plana, N.5
Garcia-Otín, A.L.6
-
16
-
-
35348840507
-
Fatty acid binding protein 4 is increased in metabolic syndrome and with thiazolidinedione treatment in diabetic patients
-
Cabré A., Lázaro I., Girona J., Manzanares J.M., Marimón F., Plana N., et al. Fatty acid binding protein 4 is increased in metabolic syndrome and with thiazolidinedione treatment in diabetic patients. Atherosclerosis 2007, 195:e150-e158. 10.1016/j.atherosclerosis.2007.04.045.
-
(2007)
Atherosclerosis
, vol.195
, pp. e150-e158
-
-
Cabré, A.1
Lázaro, I.2
Girona, J.3
Manzanares, J.M.4
Marimón, F.5
Plana, N.6
-
17
-
-
51449110846
-
Plasma fatty acid binding protein 4 is associated with atherogenic dyslipidemia in diabetes
-
Cabré A., Lázaro I., Girona J., Manzanares J.M., Marimón F., Plana N., et al. Plasma fatty acid binding protein 4 is associated with atherogenic dyslipidemia in diabetes. J. Lipid Res. 2008, 49:1746-1751. 10.1194/jlr.M800102-JLR200.
-
(2008)
J. Lipid Res.
, vol.49
, pp. 1746-1751
-
-
Cabré, A.1
Lázaro, I.2
Girona, J.3
Manzanares, J.M.4
Marimón, F.5
Plana, N.6
-
18
-
-
84871608927
-
Adipocyte fatty acid binding protein: a novel adipokine involved in the pathogenesis of metabolic and vascular disease?
-
Kralisch S., Fasshauer M. Adipocyte fatty acid binding protein: a novel adipokine involved in the pathogenesis of metabolic and vascular disease?. Diabetologia 2013, 56:10-21. 10.1007/s00125-012-2737-4.
-
(2013)
Diabetologia
, vol.56
, pp. 10-21
-
-
Kralisch, S.1
Fasshauer, M.2
-
19
-
-
84862252814
-
Fatty acid-binding protein 4 impairs the insulin-dependent nitric oxide pathway in vascular endothelial cells
-
Aragonès G., Saavedra P., Heras M., Cabré A., Girona J., Masana L. Fatty acid-binding protein 4 impairs the insulin-dependent nitric oxide pathway in vascular endothelial cells. Cardiovasc. Diabetol. 2012, 11:72. 10.1186/1475-2840-11-72.
-
(2012)
Cardiovasc. Diabetol.
, vol.11
, pp. 72
-
-
Aragonès, G.1
Saavedra, P.2
Heras, M.3
Cabré, A.4
Girona, J.5
Masana, L.6
-
20
-
-
84920730847
-
Interaction of FABP4 with plasma membrane proteins of endothelial cells
-
Saavedra P., Girona J., Aragonès G., Cabré A., Guaita S., Heras M., et al. Interaction of FABP4 with plasma membrane proteins of endothelial cells. Clin. Investig. Arterioscler. 2015, 27:26-33. 10.1016/j.arteri.2014.05.003.
-
(2015)
Clin. Investig. Arterioscler.
, vol.27
, pp. 26-33
-
-
Saavedra, P.1
Girona, J.2
Aragonès, G.3
Cabré, A.4
Guaita, S.5
Heras, M.6
-
21
-
-
84896719896
-
FABP4 induces vascular smooth muscle cell proliferation and migration through a MAPK-dependent pathway
-
Girona J., Rosales R., Plana N., Saavedra P., Masana L., Vallvé J.-C. FABP4 induces vascular smooth muscle cell proliferation and migration through a MAPK-dependent pathway. PLoS One 2013, 8:e81914. 10.1371/journal.pone.0081914.
-
(2013)
PLoS One
, vol.8
, pp. e81914
-
-
Girona, J.1
Rosales, R.2
Plana, N.3
Saavedra, P.4
Masana, L.5
Vallvé, J.-C.6
-
22
-
-
84930181000
-
Fatty acid-binding protein 4 mediates apoptosis via endoplasmic reticulum stress in mesangial cells of diabetic nephropathy
-
Yao F., Li Z., Ehara T., Yang L., Wang D., Feng L., et al. Fatty acid-binding protein 4 mediates apoptosis via endoplasmic reticulum stress in mesangial cells of diabetic nephropathy. Mol. Cell. Endocrinol. 2015, 10.1016/j.mce.2015.05.003.
-
(2015)
Mol. Cell. Endocrinol.
-
-
Yao, F.1
Li, Z.2
Ehara, T.3
Yang, L.4
Wang, D.5
Feng, L.6
-
23
-
-
84904321558
-
Cytoprotective role of the fatty acid binding protein 4 against oxidative and endoplasmic reticulum stress in 3T3-L1 adipocytes
-
Kajimoto K., Minami Y., Harashima H. Cytoprotective role of the fatty acid binding protein 4 against oxidative and endoplasmic reticulum stress in 3T3-L1 adipocytes. FEBS Open Bio 2014, 4:602-610. 10.1016/j.fob.2014.06.008.
-
(2014)
FEBS Open Bio
, vol.4
, pp. 602-610
-
-
Kajimoto, K.1
Minami, Y.2
Harashima, H.3
-
24
-
-
51449110846
-
Plasma fatty acid binding protein 4 is associated with atherogenic dyslipidemia in diabetes
-
Cabré A., Lázaro I., Girona J., Manzanares J.M., Marimón F., Plana N., et al. Plasma fatty acid binding protein 4 is associated with atherogenic dyslipidemia in diabetes. J. Lipid Res. 2008, 49:1746-1751. 10.1194/jlr.M800102-JLR200.
-
(2008)
J. Lipid Res.
, vol.49
, pp. 1746-1751
-
-
Cabré, A.1
Lázaro, I.2
Girona, J.3
Manzanares, J.M.4
Marimón, F.5
Plana, N.6
-
25
-
-
0021923858
-
Nile red: a selective fluorescent stain for intracellular lipid droplets
-
(accessed 10.03.16)
-
Greenspan P., Mayer E.P., Fowler S.D. Nile red: a selective fluorescent stain for intracellular lipid droplets. J. Cell Biol. 1985, 100:965-973. (accessed 10.03.16). http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2113505&tool=pmcentrez&rendertype=abstract.
-
(1985)
J. Cell Biol.
, vol.100
, pp. 965-973
-
-
Greenspan, P.1
Mayer, E.P.2
Fowler, S.D.3
-
26
-
-
22244446505
-
The mammalian unfolded protein response
-
Schröder M., Kaufman R.J. The mammalian unfolded protein response. Annu. Rev. Biochem. 2005, 74:739-789. 10.1146/annurev.biochem.73.011303.074134.
-
(2005)
Annu. Rev. Biochem.
, vol.74
, pp. 739-789
-
-
Schröder, M.1
Kaufman, R.J.2
-
27
-
-
10444226462
-
ER stress and the unfolded protein response
-
Schröder M., Kaufman R.J. ER stress and the unfolded protein response. Mutat. Res. 2005, 569:29-63. 10.1016/j.mrfmmm.2004.06.056.
-
(2005)
Mutat. Res.
, vol.569
, pp. 29-63
-
-
Schröder, M.1
Kaufman, R.J.2
-
28
-
-
84860483727
-
The role of endoplasmic reticulum in hepatic lipid homeostasis and stress signaling
-
Fu S., Watkins S.M., Hotamisligil G.S. The role of endoplasmic reticulum in hepatic lipid homeostasis and stress signaling. Cell Metab. 2012, 15:623-634. 10.1016/j.cmet.2012.03.007.
-
(2012)
Cell Metab.
, vol.15
, pp. 623-634
-
-
Fu, S.1
Watkins, S.M.2
Hotamisligil, G.S.3
-
29
-
-
84904015435
-
Enhanced synthesis of saturated phospholipids is associated with ER stress and lipotoxicity in palmitate treated hepatic cells
-
Leamy A.K., Egnatchik R.A., Shiota M., Ivanova P.T., Myers D.S., Brown H.A., et al. Enhanced synthesis of saturated phospholipids is associated with ER stress and lipotoxicity in palmitate treated hepatic cells. J. Lipid Res. 2014, 55:1478-1488. 10.1194/jlr.M050237.
-
(2014)
J. Lipid Res.
, vol.55
, pp. 1478-1488
-
-
Leamy, A.K.1
Egnatchik, R.A.2
Shiota, M.3
Ivanova, P.T.4
Myers, D.S.5
Brown, H.A.6
-
30
-
-
33845881411
-
Mechanisms linking obesity to insulin resistance and type 2 diabetes
-
Kahn S.E., Hull R.L., Utzschneider K.M. Mechanisms linking obesity to insulin resistance and type 2 diabetes. Nature 2006, 444:840-846. 10.1038/nature05482.
-
(2006)
Nature
, vol.444
, pp. 840-846
-
-
Kahn, S.E.1
Hull, R.L.2
Utzschneider, K.M.3
-
31
-
-
78649450627
-
Bip overexpression, but not CHOP inhibition, attenuates fatty-acid-induced endoplasmic reticulum stress and apoptosis in HepG2 liver cells
-
Gu X., Li K., Laybutt D.R., He M., Zhao H.-L., Chan J.C.N., et al. Bip overexpression, but not CHOP inhibition, attenuates fatty-acid-induced endoplasmic reticulum stress and apoptosis in HepG2 liver cells. Life Sci. 2010, 87:724-732. 10.1016/j.lfs.2010.10.012.
-
(2010)
Life Sci.
, vol.87
, pp. 724-732
-
-
Gu, X.1
Li, K.2
Laybutt, D.R.3
He, M.4
Zhao, H.-L.5
Chan, J.C.N.6
-
32
-
-
84887620615
-
When ER stress reaches a dead end
-
Urra H., Dufey E., Lisbona F., Rojas-Rivera D., Hetz C. When ER stress reaches a dead end. Biochim. Biophys. Acta 2013, 1833:3507-3517. 10.1016/j.bbamcr.2013.07.024.
-
(2013)
Biochim. Biophys. Acta
, vol.1833
, pp. 3507-3517
-
-
Urra, H.1
Dufey, E.2
Lisbona, F.3
Rojas-Rivera, D.4
Hetz, C.5
-
33
-
-
34250904186
-
Treatment of diabetes and atherosclerosis by inhibiting fatty-acid-binding protein aP2
-
Furuhashi M., Tuncman G., Görgün C.Z., Makowski L., Atsumi G., Vaillancourt E., et al. Treatment of diabetes and atherosclerosis by inhibiting fatty-acid-binding protein aP2. Nature 2007, 447:959-965. 10.1038/nature05844.
-
(2007)
Nature
, vol.447
, pp. 959-965
-
-
Furuhashi, M.1
Tuncman, G.2
Görgün, C.Z.3
Makowski, L.4
Atsumi, G.5
Vaillancourt, E.6
-
34
-
-
84872388467
-
Pharmacological inhibition of adipocyte fatty acid binding protein alleviates both acute liver injury and non-alcoholic steatohepatitis in mice
-
Hoo R.L.C., Lee I.P.C., Zhou M., Wong J.Y.L., Hui X., Xu A., et al. Pharmacological inhibition of adipocyte fatty acid binding protein alleviates both acute liver injury and non-alcoholic steatohepatitis in mice. J. Hepatol. 2013, 58:358-364. 10.1016/j.jhep.2012.10.022.
-
(2013)
J. Hepatol.
, vol.58
, pp. 358-364
-
-
Hoo, R.L.C.1
Lee, I.P.C.2
Zhou, M.3
Wong, J.Y.L.4
Hui, X.5
Xu, A.6
-
35
-
-
77958154359
-
Liver fatty acid-binding protein and obesity
-
Atshaves B.P., Martin G.G., Hostetler H.A., McIntosh A.L., Kier A.B., Schroeder F. Liver fatty acid-binding protein and obesity. J. Nutr. Biochem. 2010, 21:1015-1032. 10.1016/j.jnutbio.2010.01.005.
-
(2010)
J. Nutr. Biochem.
, vol.21
, pp. 1015-1032
-
-
Atshaves, B.P.1
Martin, G.G.2
Hostetler, H.A.3
McIntosh, A.L.4
Kier, A.B.5
Schroeder, F.6
-
36
-
-
70349260934
-
Adipocyte fatty acid-binding protein suppresses cardiomyocyte contraction: a new link between obesity and heart disease
-
Lamounier-Zepter V., Look C., Alvarez J., Christ T., Ravens U., Schunck W.-H., et al. Adipocyte fatty acid-binding protein suppresses cardiomyocyte contraction: a new link between obesity and heart disease. Circ. Res. 2009, 105:326-334. 10.1161/CIRCRESAHA.109.200501.
-
(2009)
Circ. Res.
, vol.105
, pp. 326-334
-
-
Lamounier-Zepter, V.1
Look, C.2
Alvarez, J.3
Christ, T.4
Ravens, U.5
Schunck, W.-H.6
|