메뉴 건너뛰기




Volumn 38, Issue , 2015, Pages S8-S13

Shared Genetic basis for type 1 diabetes, islet autoantibodies, and autoantibodies associated with other immune-mediated diseases in families with type 1 diabetes

Author keywords

[No Author keywords available]

Indexed keywords

21 HYDROXYLASE ANTIBODY; AUTOANTIBODY; GLUTAMATE DECARBOXYLASE ANTIBODY; PANCREAS ISLET CELL ANTIBODY; PARIETAL CELL ANTIBODY; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE ANTIBODY; THYROID PEROXIDASE ANTIBODY; UNCLASSIFIED DRUG; ZINC TRANSPORTER 8 ANTIBODY; AUTOANTIGEN;

EID: 84965186550     PISSN: 01495992     EISSN: 19355548     Source Type: Journal    
DOI: 10.2337/dcs15-2003     Document Type: Conference Paper
Times cited : (51)

References (43)
  • 1
    • 67349199566 scopus 로고    scopus 로고
    • Genomewide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes
    • Barrett JC, Clayton DG, Concannon P, et al.; Type 1 Diabetes Genetics Consortium. Genomewide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes. Nat Genet 2009;41:703-707
    • (2009) Nat Genet , vol.41 , pp. 703-707
    • Type 1 Diabetes Genetics Consortium1    Barrett, J.C.2    Clayton, D.G.3    Concannon, P.4
  • 2
    • 0842288452 scopus 로고    scopus 로고
    • Stratification of type 1 diabetes risk on the basis of islet autoantibody characteristics
    • Achenbach P,Warncke K, Reiter J, et al. Stratification of type 1 diabetes risk on the basis of islet autoantibody characteristics. Diabetes 2004;53:384-392
    • (2004) Diabetes , vol.53 , pp. 384-392
    • Achenbach, P.1    Warncke, K.2    Reiter, J.3
  • 3
    • 36749011882 scopus 로고    scopus 로고
    • The cation efflux transporter ZnT8 (Slc30A8) is a major autoantigen in human type 1 diabetes
    • Wenzlau JM, Juhl K, Yu L, et al. The cation efflux transporter ZnT8 (Slc30A8) is a major autoantigen in human type 1 diabetes. Proc Natl Acad Sci U S A 2007;104:17040-17045
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 17040-17045
    • Wenzlau, J.M.1    Juhl, K.2    Yu, L.3
  • 4
    • 80053416976 scopus 로고    scopus 로고
    • Evidence that HLA class I and II associations with type 1 diabetes, autoantibodies to GAD and autoantibodies to IA-2, are distinct
    • Howson JM, Stevens H, Smyth DJ, et al. Evidence that HLA class I and II associations with type 1 diabetes, autoantibodies to GAD and autoantibodies to IA-2, are distinct. Diabetes 2011;60:2635-2644
    • (2011) Diabetes , vol.60 , pp. 2635-2644
    • Howson, J.M.1    Stevens, H.2    Smyth, D.J.3
  • 5
    • 67650501545 scopus 로고    scopus 로고
    • The effect of the MHC locus on autoantibodies in type 1 diabetes
    • Qu HQ, Polychronakos C. The effect of the MHC locus on autoantibodies in type 1 diabetes. J Med Genet 2009;46:469-471
    • (2009) J Med Genet , vol.46 , pp. 469-471
    • Qu, H.Q.1    Polychronakos, C.2
  • 7
    • 84866372920 scopus 로고    scopus 로고
    • Genetic association of zinc transporter 8 (ZnT8) autoantibodies in type 1 diabetes cases
    • Howson JM, Krause S, Stevens H, et al. Genetic association of zinc transporter 8 (ZnT8) autoantibodies in type 1 diabetes cases. Diabetologia 2012;55:1978-1984
    • (2012) Diabetologia , vol.55 , pp. 1978-1984
    • Howson, J.M.1    Krause, S.2    Stevens, H.3
  • 8
    • 77954288805 scopus 로고    scopus 로고
    • Genetics of type 1 diabetes: What's next?
    • Pociot F, Akolkar B, Concannon P, et al. Genetics of type 1 diabetes: what's next? Diabetes 2010;59:1561-1571
    • (2010) Diabetes , vol.59 , pp. 1561-1571
    • Pociot, F.1    Akolkar, B.2    Concannon, P.3
  • 10
    • 84965188824 scopus 로고    scopus 로고
    • Design and measurement of nonislet-specific autoantibodies for the Type 1 Diabetes Genetics Consortium Autoantibody Workshop
    • Akolkar B, Hilner J, Nierras CR. Design and measurement of nonislet-specific autoantibodies for the Type 1 Diabetes Genetics Consortium Autoantibody Workshop. Diabetes Care 2015; 38(Suppl. 2):S4-S7
    • (2015) Diabetes Care , vol.38 , pp. S4-S7
    • Akolkar, B.1    Hilner, J.2    Nierras, C.R.3
  • 11
    • 84984691321 scopus 로고    scopus 로고
    • Changes in zinc transporter 8 autoantibodies following type 1 diabetes onset: The Type 1 Diabetes Genetics Consortium Autoantibody Workshop
    • Wenzlau JM, Frisch LM, Hutton JC, Fain PR, Davidson HW. Changes in zinc transporter 8 autoantibodies following type 1 diabetes onset: the Type 1 Diabetes Genetics Consortium Autoantibody Workshop. Diabetes Care 2015; 38(Suppl. 2):S14-S20
    • (2015) Diabetes Care , vol.38 , pp. S14-S20
    • Wenzlau, J.M.1    Frisch, L.M.2    Hutton, J.C.3    Fain, P.R.4    Davidson, H.W.5
  • 12
    • 29844444766 scopus 로고    scopus 로고
    • The R Package geepack for generalized estimating equations
    • Halekoh U, Hojsgaard S, Yan J. The R Package geepack for generalized estimating equations. J Stat Softw 2006;15:1-11
    • (2006) J Stat Softw , vol.15 , pp. 1-11
    • Halekoh, U.1    Hojsgaard, S.2    Yan, J.3
  • 13
    • 77649173768 scopus 로고
    • Longitudinal data-analysis using generalized linear-models
    • Liang KY, Zeger SL. Longitudinal data-analysis using generalized linear-models. Biometrika 1986; 73:13-22
    • (1986) Biometrika , vol.73 , pp. 13-22
    • Liang, K.Y.1    Zeger, S.L.2
  • 14
    • 58149348575 scopus 로고    scopus 로고
    • Two single nucleotide polymorphisms identify the highestrisk diabetes HLA genotype: Potential for rapid screening
    • Barker JM, Triolo TM, Aly TA, et al. Two single nucleotide polymorphisms identify the highestrisk diabetes HLA genotype: potential for rapid screening. Diabetes 2008;57:3152-3155
    • (2008) Diabetes , vol.57 , pp. 3152-3155
    • Barker, J.M.1    Triolo, T.M.2    Aly, T.A.3
  • 15
    • 63249132182 scopus 로고    scopus 로고
    • Comment on: Barker et al. (2008) Two single nucleotide polymorphisms identify the highest-risk diabetes HLA genotype: Diabetes 57:3152-3155, 2008
    • Romanos J, Wijmenga C. Comment on: Barker et al. (2008) Two single nucleotide polymorphisms identify the highest-risk diabetes HLA genotype: Diabetes 57:3152-3155, 2008. Diabetes 2009;58:e1
    • (2009) Diabetes , vol.58 , pp. e1
    • Romanos, J.1    Wijmenga, C.2
  • 16
    • 78349272440 scopus 로고    scopus 로고
    • Genetic susceptibility to autoimmune thyroid disease: Past, present, and future
    • Tomer Y. Genetic susceptibility to autoimmune thyroid disease: past, present, and future. Thyroid 2010;20:715-725
    • (2010) Thyroid , vol.20 , pp. 715-725
    • Tomer, Y.1
  • 17
    • 82255192188 scopus 로고    scopus 로고
    • Dense genotyping identifies and localizes multiple common and rare variant association signals in celiac disease
    • Trynka G, Hunt KA, Bockett NA, et al.; Spanish Consortium on the Genetics of Coeliac Disease (CEGEC); PreventCD Study Group; Wellcome Trust Case Control Consortium (WTCCC). Dense genotyping identifies and localizes multiple common and rare variant association signals in celiac disease. Nat Genet 2011;43: 1193-1201
    • (2011) Nat Genet , vol.43 , pp. 1193-1201
    • Trynka, G.1    Hunt, K.A.2    Bockett, N.A.3
  • 18
    • 58149091678 scopus 로고    scopus 로고
    • Shared and distinct genetic variants in type 1 diabetes and celiac disease
    • Smyth DJ, Plagnol V, Walker NM, et al. Shared and distinct genetic variants in type 1 diabetes and celiac disease. N Engl J Med 2008;359:2767-2777
    • (2008) N Engl J Med , vol.359 , pp. 2767-2777
    • Smyth, D.J.1    Plagnol, V.2    Walker, N.M.3
  • 19
    • 34547756980 scopus 로고    scopus 로고
    • Genomic polymorphism at the interferon-induced helicase (IFIH1) locus contributes to Graves' disease susceptibility
    • Sutherland A, Davies J, Owen CJ, et al. Genomic polymorphism at the interferon-induced helicase (IFIH1) locus contributes to Graves' disease susceptibility. J Clin Endocrinol Metab 2007;92:3338-3341
    • (2007) J Clin Endocrinol Metab , vol.92 , pp. 3338-3341
    • Sutherland, A.1    Davies, J.2    Owen, C.J.3
  • 21
    • 35748981184 scopus 로고    scopus 로고
    • Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants
    • Burton PR, Clayton DG, Cardon LR, et al.; Wellcome Trust Case Control Consortium; Australo-Anglo-American Spondylitis Consortium (TASC); Biologics in RA Genetics and Genomics Study Syndicate (BRAGGS) Steering Committee; Breast Cancer Susceptibility Collaboration (UK). Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants. Nat Genet 2007;39:1329-1337
    • (2007) Nat Genet , vol.39 , pp. 1329-1337
    • Burton, P.R.1    Clayton, D.G.2    Cardon, L.R.3
  • 22
    • 33746028777 scopus 로고    scopus 로고
    • Intracellular pattern recognition receptors in the host response
    • Meylan E, Tschopp J, Karin M. Intracellular pattern recognition receptors in the host response. Nature 2006;442:39-44
    • (2006) Nature , vol.442 , pp. 39-44
    • Meylan, E.1    Tschopp, J.2    Karin, M.3
  • 23
    • 0033624114 scopus 로고    scopus 로고
    • Enterovirus infection as a risk factor for beta-cell autoimmunity in a prospectively observed birth cohort: The Finnish Diabetes Prediction and Prevention Study
    • Lönnrot M, Korpela K, Knip M, et al. Enterovirus infection as a risk factor for beta-cell autoimmunity in a prospectively observed birth cohort: the Finnish Diabetes Prediction and Prevention Study. Diabetes 2000;49:1314-1318
    • (2000) Diabetes , vol.49 , pp. 1314-1318
    • Lönnrot, M.1    Korpela, K.2    Knip, M.3
  • 24
    • 33745240931 scopus 로고    scopus 로고
    • A genome-wide association study of nonsynonymous SNPs identifies a type 1 diabetes locus in the interferon-induced helicase (IFIH1) region
    • Smyth DJ, Cooper JD, Bailey R, et al. A genome-wide association study of nonsynonymous SNPs identifies a type 1 diabetes locus in the interferon-induced helicase (IFIH1) region. Nat Genet 2006;38:617-619
    • (2006) Nat Genet , vol.38 , pp. 617-619
    • Smyth, D.J.1    Cooper, J.D.2    Bailey, R.3
  • 25
    • 77649326700 scopus 로고    scopus 로고
    • MDA5 and PTPN2, two candidate genes for type 1 diabetes, modify pancreatic beta-cell responses to the viral by-product double-stranded RNA
    • Colli ML, Moore F, Gurzov EN, Ortis F, Eizirik DL. MDA5 and PTPN2, two candidate genes for type 1 diabetes, modify pancreatic beta-cell responses to the viral by-product double-stranded RNA. Hum Mol Genet 2010;19:135-146
    • (2010) Hum Mol Genet , vol.19 , pp. 135-146
    • Colli, M.L.1    Moore, F.2    Gurzov, E.N.3    Ortis, F.4    Eizirik, D.L.5
  • 26
    • 12144291502 scopus 로고    scopus 로고
    • A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetes
    • Bottini N, Musumeci L, Alonso A, et al. A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetes. Nat Genet 2004;36:337-338
    • (2004) Nat Genet , vol.36 , pp. 337-338
    • Bottini, N.1    Musumeci, L.2    Alonso, A.3
  • 27
    • 28444469783 scopus 로고    scopus 로고
    • Autoimmune-associated lymphoid tyrosine phosphatase is a gain-of-function variant
    • Vang T, Congia M, Macis MD, et al. Autoimmune-associated lymphoid tyrosine phosphatase is a gain-of-function variant. Nat Genet 2005;37:1317-1319
    • (2005) Nat Genet , vol.37 , pp. 1317-1319
    • Vang, T.1    Congia, M.2    Macis, M.D.3
  • 28
    • 7044253358 scopus 로고    scopus 로고
    • Replication of an association between the lymphoid tyrosine phosphatase locus (LYP/PTPN22) with type 1 diabetes, and evidence for its role as a general autoimmunity locus
    • Smyth D, Cooper JD, Collins JE, et al. Replication of an association between the lymphoid tyrosine phosphatase locus (LYP/PTPN22) with type 1 diabetes, and evidence for its role as a general autoimmunity locus. Diabetes 2004;53: 3020-3023
    • (2004) Diabetes , vol.53 , pp. 3020-3023
    • Smyth, D.1    Cooper, J.D.2    Collins, J.E.3
  • 29
    • 42549159759 scopus 로고    scopus 로고
    • Mutation screening of PTPN22: Association of the 1858T-allele with Addison's disease
    • Skinningsrud B, Husebye ES, Gervin K, et al. Mutation screening of PTPN22: association of the 1858T-allele with Addison's disease. Eur J Hum Genet 2008;16:977-982
    • (2008) Eur J Hum Genet , vol.16 , pp. 977-982
    • Skinningsrud, B.1    Husebye, E.S.2    Gervin, K.3
  • 30
    • 60349083325 scopus 로고    scopus 로고
    • The tryptophan 620 allele of the lymphoid tyrosine phosphatase (PTPN22) gene predisposes to autoimmune Addison's disease
    • Roycroft M, Fichna M, McDonald D, et al. The tryptophan 620 allele of the lymphoid tyrosine phosphatase (PTPN22) gene predisposes to autoimmune Addison's disease. Clin Endocrinol (Oxf) 2009;70:358-362
    • (2009) Clin Endocrinol (Oxf) , vol.70 , pp. 358-362
    • Roycroft, M.1    Fichna, M.2    McDonald, D.3
  • 31
    • 0034658354 scopus 로고    scopus 로고
    • Cloning and characterization of human Lnk, an adaptor protein with pleckstrin homology and Src homology 2 domains that can inhibit T cell activation
    • Li Y, He X, Schembri-King J, Jakes S, Hayashi J. Cloning and characterization of human Lnk, an adaptor protein with pleckstrin homology and Src homology 2 domains that can inhibit T cell activation. J Immunol 2000;164:5199-5206
    • (2000) J Immunol , vol.164 , pp. 5199-5206
    • Li, Y.1    He, X.2    Schembri-King, J.3    Jakes, S.4    Hayashi, J.5
  • 32
    • 2942537762 scopus 로고    scopus 로고
    • The transcriptional programme of antibody class switching involves the repressor Bach2
    • Muto A, Tashiro S, Nakajima O, et al. The transcriptional programme of antibody class switching involves the repressor Bach2. Nature 2004;429:566-571
    • (2004) Nature , vol.429 , pp. 566-571
    • Muto, A.1    Tashiro, S.2    Nakajima, O.3
  • 33
    • 84903136445 scopus 로고    scopus 로고
    • BACH2, a candidate risk gene for type 1 diabetes, regulates apoptosis in pancreatic b-cells via JNK1 modulation and crosstalk with the candidate gene PTPN2
    • Marroquí L, Santin I, Dos Santos RS, Marselli L, Marchetti P, Eizirik DL. BACH2, a candidate risk gene for type 1 diabetes, regulates apoptosis in pancreatic b-cells via JNK1 modulation and crosstalk with the candidate gene PTPN2. Diabetes 2014;63:2516-2527
    • (2014) Diabetes , vol.63 , pp. 2516-2527
    • Marroquí, L.1    Santin, I.2    Dos Santos, R.S.3    Marselli, L.4    Marchetti, P.5    Eizirik, D.L.6
  • 34
    • 0030734382 scopus 로고    scopus 로고
    • Codon 17 polymorphism of the cytotoxic T lymphocyte antigen 4 gene in Hashimoto's thyroiditis and Addison's disease
    • Donner H, Braun J, Seidl C, et al. Codon 17 polymorphism of the cytotoxic T lymphocyte antigen 4 gene in Hashimoto's thyroiditis and Addison's disease. J Clin Endocrinol Metab 1997;82:4130-4132
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 4130-4132
    • Donner, H.1    Braun, J.2    Seidl, C.3
  • 35
    • 0030816688 scopus 로고    scopus 로고
    • A CTLA-4 gene polymorphism is associated with both Graves disease and autoimmune hypothyroidism
    • Kotsa K, Watson PF, Weetman APA. A CTLA-4 gene polymorphism is associated with both Graves disease and autoimmune hypothyroidism. Clin Endocrinol (Oxf) 1997;46: 551-554
    • (1997) Clin Endocrinol (Oxf) , vol.46 , pp. 551-554
    • Kotsa, K.1    Watson, P.F.2    Weetman, A.P.A.3
  • 37
    • 0036319041 scopus 로고    scopus 로고
    • Genetic effects on age-dependent onset and islet cell autoantibody markers in type 1 diabetes
    • Graham J, Hagopian WA, Kockum I, et al.; Diabetes Incidence in Sweden Study Group; Swedish Childhood Diabetes Study Group. Genetic effects on age-dependent onset and islet cell autoantibody markers in type 1 diabetes. Diabetes 2002;51:1346-1355
    • (2002) Diabetes , vol.51 , pp. 1346-1355
    • Graham, J.1    Hagopian, W.A.2    Kockum, I.3
  • 38
    • 0024492512 scopus 로고
    • Evidence for a primary association of celiac disease to a particular HLA-DQ alpha/beta heterodimer
    • Sollid LM, Markussen G, Ek J, Gjerde H, Vartdal F, Thorsby E. Evidence for a primary association of celiac disease to a particular HLA-DQ alpha/beta heterodimer. J Exp Med 1989;169:345-350
    • (1989) J Exp Med , vol.169 , pp. 345-350
    • Sollid, L.M.1    Markussen, G.2    Ek, J.3    Gjerde, H.4    Vartdal, F.5    Thorsby, E.6
  • 39
    • 0034695893 scopus 로고    scopus 로고
    • The intestinal T cell response to alphagliadin in adult celiac disease is focused on a single deamidated glutamine targeted by tissue transglutaminase
    • Arentz-Hansen H, Körner R, Molberg O, et al. The intestinal T cell response to alphagliadin in adult celiac disease is focused on a single deamidated glutamine targeted by tissue transglutaminase. J Exp Med 2000;191: 603-612
    • (2000) J Exp Med , vol.191 , pp. 603-612
    • Arentz-Hansen, H.1    Körner, R.2    Molberg, O.3
  • 40
    • 19944422075 scopus 로고    scopus 로고
    • Regression mapping of association between the human leukocyte antigen region and Graves disease
    • Simmonds MJ, Howson JM, Heward JM, et al. Regression mapping of association between the human leukocyte antigen region and Graves disease. Am J Hum Genet 2005;76: 157-163
    • (2005) Am J Hum Genet , vol.76 , pp. 157-163
    • Simmonds, M.J.1    Howson, J.M.2    Heward, J.M.3
  • 41
    • 38049068750 scopus 로고    scopus 로고
    • The HLA gene complex in thyroid autoimmunity: From epidemiology to etiology
    • Jacobson EM, Huber A, Tomer Y. The HLA gene complex in thyroid autoimmunity: from epidemiology to etiology. J Autoimmun 2008; 30:58-62
    • (2008) J Autoimmun , vol.30 , pp. 58-62
    • Jacobson, E.M.1    Huber, A.2    Tomer, Y.3
  • 42
    • 80053470015 scopus 로고    scopus 로고
    • Multiple loci in the HLA complex are associated with Addison's disease
    • Skinningsrud B, Lie BA, Lavant E, et al. Multiple loci in the HLA complex are associated with Addison's disease. J Clin Endocrinol Metab 2011;96:E1703-E1708
    • (2011) J Clin Endocrinol Metab , vol.96 , pp. E1703-E1708
    • Skinningsrud, B.1    Lie, B.A.2    Lavant, E.3
  • 43
    • 84882449068 scopus 로고    scopus 로고
    • Genetic insights into common pathways and complex relationships among immunemediated diseases
    • Parkes M, Cortes A, van Heel DA, Brown MA. Genetic insights into common pathways and complex relationships among immunemediated diseases. Nat Rev Genet 2013;14: 661-673
    • (2013) Nat Rev Genet , vol.14 , pp. 661-673
    • Parkes, M.1    Cortes, A.2    Van Heel, D.A.3    Brown, M.A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.