Codon 17 polymorphism of the cytotoxic T lymphocyte antigen 4 gene in Hashimoto's thyroiditis and Addison's disease

Journal of Clinical Endocrinology and Metabolism

Volumn 82, Issue 12, 1997, Pages 4130-4132

  Donner, Horst ^a   Braun, Jens ^a   Seidl, Christian ^b   Rau, Harald ^a   Finke, Reinhard ^d   Ventz, Manfred ^d   Walfish, Paul G ^c   Usadel, Klaus H ^a   Badenhoop, Klaus ^a  

^a UNIVERSITY HOSPITAL FRANKFURT   (Germany)

^b Institute of Transfusion Medicine and Immunohaematology   (Germany)

^c UNIVERSITY OF TORONTO   (Canada)

^d CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ADDISON DISEASE; ARTICLE; AUTOIMMUNITY; CODON; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; ENDOCRINE DISEASE; GENE LOCUS; GENETIC SUSCEPTIBILITY; HASHIMOTO DISEASE; HUMAN; MAJOR CLINICAL STUDY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SINGLE STRAND CONFORMATION POLYMORPHISM; THYROID DISEASE;

EID: 0030734382     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jc.82.12.4130     Document Type: Article

References (14)

1. Nistico L, Buzzetti R, Pritchard LE, et al. 1996 The CTLA-4 gene region of chromosome 2q33 is linked to, and associated with, type 1 diabetes. Hum Mol Genet. 5:1075-1080.
2. Reiser H, Stadecker MJ. 1996 Costimulatory B7 molecules in the pathogenesis of infectious and autoimmune diseases. N Engl J Med. 335:1369-1377.
3. Gribben JG, Freeman GJ, Boussiotis VA, et al. 1995 CTLA4 mediates antigen-specific apoptosis of human T cells. Proc Natl Acad Sci USA. 92:811-815.
4. Karandikar NJ, Vanderlugt CL, Walunas TL, Miller SD, Bluestone JA. 1996 CTLA-4: a negative regulator of autoimmune disease. J Exp Med. 184:783-788.
5. Freeman M, Weetman AP. 1992 T and B cell reactivity to adrenal antigens in autoimmune Addison's disease. Clin Exp Immunol. 88:275-279.
6. Weetman AP, McGregor AM. 1994 Autoimmune thyroid disease: further developments in our understanding. Endocr Rev. 15:788-830.
7. Badenhoop K, Walfish PG, Rau H, et al. 1995 Susceptibility and resistance alleles of human leukocyte antigen (HLA) DQA1 and HLA DQB1 are shared in endocrine autoimmune disease. J Clin Endocrinol Metab. 80:2112-2117.
8. Donner H, Rau H, Walfish PG, et al. 1997 CTLA4 alanine-17 confers genetic susceptibility to Graves' disease and to type 1 diabetes mellitus. J Clin Endocrinol Metab. 82:143-146.
9. Harper K, Balzano C, Rouvier E, Mattel M-G, Luciani M-F, Golstein P. 1991 CTLA-4 and CD28 activated lymphocyte molecules are closely related in both mouse and human as to sequence, message expression, gene structure, and chromosomal location. J Immunol. 147:1037-1044.
10. Yanagawa T, Hidaka Y, Guimaraes V, Soliman M, DeGroot LJ. 1995 CTLA-4 gene polymorphism associated with Graves' disease in a Caucasian population. J Clin Endocrinol Metab. 80:41-45.
11. Kotsa K, Watson P, Weetman AP. 1997 A CTLA-4 gene polymorphism is associated with both Graves' disease and Hashimoto's thyroiditis. Clin Endocrinol (Oxf). 46:551-554.
12. Seidl C, Donner H, Fischer B et al. 1997 CTLA4 codon 17 dimorphism in patients with rheumatoid arthritis. Tissue Antigens. In press.
13. Heuer M, Aust G, Ode-Hakim S, Scherbaum WA. 1996 Different cytokine mRNA profiles in Graves' disease, Hashimoto's thyroiditis and non-autoimmune thyroid disorders determined by quantitative reverse trancriptase polymerase chain reaction (RT-PCR). Thyroid. 6:97-106.
14. Matsuoka N, Eguchi K, Kawakami A, et al. 1996 Lack of B7-1/BB1 and B7-2/B70 expression on thyrocytes of patients with Graves' disease. Delivery of costimulatory signals from bystander professional antigen-presenting cells. J Clin Endocrinol Metab. 81:4137-4143.