The intestinal T cell response to α-gliadin in adult celiac disease is focused on a single deamidated glutamine targeted by tissue transglutaminase

Journal of Experimental Medicine

Volumn 191, Issue 4, 2000, Pages 603-612

  Arentz Hansen, Helene ^a   Körner, Roman ^b   Molberg, Øyvind ^a   Quarsten, Hanne ^a   Vader, Willemijn ^d   Kooy, Yvonne M C ^d   Lundin, Knut E A ^a,c   Koning, Frits ^d   Roepstorff, Peter ^b   Sollid, Ludvig M ^a   McAdam, Stephen N ^a  

^a UNIVERSITY OF OSLO   (Norway)

^b UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

^c ULLEVÅL UNIVERSITY HOSPITAL   (Norway)

^d LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Gluten; HLA DQ2; Modification; Mucosal immunity; Oral tolerance

Indexed keywords

EPITOPE; FOOD ANTIGEN; GLIADIN; GLUTAMIC ACID; GLUTAMINE; HLA DQ ANTIGEN; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE;

ARTICLE; CELIAC DISEASE; DEAMINATION; HUMAN; HUMAN CELL; MAJOR HISTOCOMPATIBILITY COMPLEX; MUCOSAL IMMUNITY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN TARGETING; T LYMPHOCYTE;

ADULT; AMINO ACID SEQUENCE; BINDING SITES; CELIAC DISEASE; CELL LINE; CHILD; CONSENSUS SEQUENCE; GLIADIN; GLUTAMINE; GTP-BINDING PROTEINS; HLA-DQ ANTIGENS; HUMANS; IMMUNITY, MUCOSAL; INTESTINAL MUCOSA; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; RECOMBINANT PROTEINS; T-LYMPHOCYTES; TRANSGLUTAMINASES;

EID: 0034695893     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.191.4.603     Document Type: Article

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