Notch and TGFβ form a positive regulatory loop and regulate EMT in epithelial ovarian cancer cells

Cellular Signalling

Volumn 28, Issue 8, 2016, Pages 838-849

  Zhou, Jiesi ^a,b   Jain, Saket ^a   Azad, Abul K ^a   Xu, Xia ^a   Yu, Hai Chuan ^a   Xu, Zhihua ^a   Godbout, Roseline ^a   Fu, YangXin ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

^b SHANTOU UNIVERSITY MEDICAL COLLEGE   (China)

Author keywords

EMT; Epithelial ovarian cancer; Notch; TGF

Indexed keywords

CYTOKERATIN 10; CYTOKERATIN 13; CYTOKERATIN 18; CYTOKERATIN 4; CYTOKERATIN 5; CYTOKERATIN 6; CYTOKERATIN 8; GAMMA SECRETASE INHIBITOR; JAGGED1; NOTCH1 RECEPTOR; SMAD PROTEIN; TRANSCRIPTION FACTOR HES 1; TRANSCRIPTION FACTOR SLUG; TRANSCRIPTION FACTOR SNAIL; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 1; UVOMORULIN; CADHERIN; CDH1 PROTEIN, HUMAN; HES1 PROTEIN, HUMAN; JAG1 PROTEIN, HUMAN; LIGAND; NOTCH RECEPTOR; PROTEIN JAGGED 1; PROTEIN SERINE THREONINE KINASE; TGF-BETA TYPE I RECEPTOR; TRANSFORMING GROWTH FACTOR BETA RECEPTOR;

ARTICLE; CARCINOGENESIS; CELL MIGRATION; CELL MOTILITY; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME REPRESSION; EPITHELIAL MESENCHYMAL TRANSITION; FEMALE; GENE TARGETING; HES1 GENE; HUMAN; HUMAN CELL; OVARY CARCINOMA; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; UPREGULATION; CELL MOTION; METABOLISM; NEOPLASM; OVARY TUMOR; PATHOLOGY; TUMOR CELL LINE;

CADHERINS; CELL LINE, TUMOR; CELL MOVEMENT; EPITHELIAL-MESENCHYMAL TRANSITION; FEMALE; HUMANS; JAGGED-1 PROTEIN; LIGANDS; NEOPLASMS, GLANDULAR AND EPITHELIAL; OVARIAN NEOPLASMS; PROTEIN-SERINE-THREONINE KINASES; RECEPTORS, NOTCH; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; SIGNAL TRANSDUCTION; SMAD PROTEINS; TRANSCRIPTION FACTOR HES-1; TRANSFORMING GROWTH FACTOR BETA; UP-REGULATION;

EID: 84965018394     PISSN: 08986568     EISSN: 18733913     Source Type: Journal    
DOI: 10.1016/j.cellsig.2016.03.016     Document Type: Article

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