메뉴 건너뛰기




Volumn 2, Issue APR, 2012, Pages

Epithelial-mesenchymal transition in ovarian carcinoma

Author keywords

Chemotherapy; Epithelial mesenchymal transition; Mesenchymal epithelial transition; Metastasis; Ovarian carcinoma; Prognosis; Tumor progression

Indexed keywords

BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; CHEMOKINE RECEPTOR CXCR4; CISPLATIN; CLAUDIN; CLAUDIN 4; CYCLOOXYGENASE 2; ENDOTHELIN 1; EPIDERMAL GROWTH FACTOR; ESTRADIOL; FIBROBLAST GROWTH FACTOR; MATRIX METALLOPROTEINASE; MICRORNA; PARATHYROID HORMONE; PLATELET DERIVED GROWTH FACTOR; PROSTAGLANDIN E2; SCATTER FACTOR; SEMAPHORIN; SEMAPHORIN 3E; SOMATOMEDIN; STEM CELL FACTOR; TRANSCRIPTION FACTOR; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; UVOMORULIN; VASCULOTROPIN; ZEB PROTEIN; ZINC FINGER TRANSCRIPTION FACTOR;

EID: 84870233792     PISSN: None     EISSN: 2234943X     Source Type: Journal    
DOI: 10.3389/fonc.2012.00033     Document Type: Review
Times cited : (134)

References (138)
  • 1
    • 67650996280 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transitions: the importance of changing cell state in development and disease
    • Acloque, H., Adams, M. S., Fishwick, K., Bronner-Fraser, M., and Nieto, M. A. (2009). Epithelial-mesenchymal transitions: the importance of changing cell state in development and disease. J. Clin. Invest. 119, 1438-1449.
    • (2009) J. Clin. Invest. , vol.119 , pp. 1438-1449
    • Acloque, H.1    Adams, M.S.2    Fishwick, K.3    Bronner-Fraser, M.4    Nieto, M.A.5
  • 2
    • 0043240182 scopus 로고    scopus 로고
    • Ovarian cancer: strategies for overcoming resistance to chemotherapy
    • Agarwal, R., and Kaye, S. B. (2003). Ovarian cancer: strategies for overcoming resistance to chemotherapy. Nat. Rev. Cancer 3, 502-516.
    • (2003) Nat. Rev. Cancer , vol.3 , pp. 502-516
    • Agarwal, R.1    Kaye, S.B.2
  • 3
    • 35848946387 scopus 로고    scopus 로고
    • Epithelial-mesenchymal interconversions in normal ovarian surface epithelium and ovarian carcinomas: an exception to the norm
    • Ahmed, N., Thompson, E. W., and Quinn, M. A. (2007). Epithelial-mesenchymal interconversions in normal ovarian surface epithelium and ovarian carcinomas: an exception to the norm. J. Cell. Physiol. 213, 581-588.
    • (2007) J. Cell. Physiol. , vol.213 , pp. 581-588
    • Ahmed, N.1    Thompson, E.W.2    Quinn, M.A.3
  • 7
    • 33750179033 scopus 로고    scopus 로고
    • Differential gene expression profiles between tumor biopsies and short-term primary cultures of ovarian serous carcinomas: identification of novel molecular biomarkers for early diagnosis and therapy
    • Bignotti, E., Tassi, R. A., Calza, S., Ravaggi, A., Romani, C., Rossi, E., Falchetti, M., Odicino, F. E., Pecorelli, S., and Santin, A. D. (2006). Differential gene expression profiles between tumor biopsies and short-term primary cultures of ovarian serous carcinomas: identification of novel molecular biomarkers for early diagnosis and therapy. Gynecol. Oncol. 103, 405-416.
    • (2006) Gynecol. Oncol. , vol.103 , pp. 405-416
    • Bignotti, E.1    Tassi, R.A.2    Calza, S.3    Ravaggi, A.4    Romani, C.5    Rossi, E.6    Falchetti, M.7    Odicino, F.E.8    Pecorelli, S.9    Santin, A.D.10
  • 8
    • 38549154187 scopus 로고    scopus 로고
    • The E-cadherin repressor Snail is associated with lower overall survival of ovarian cancer patients
    • Blechschmidt, K., Sassen, S., Schmalfeldt, B., Schuster, T., Höfler, H., and Becker, K. F. (2008). The E-cadherin repressor Snail is associated with lower overall survival of ovarian cancer patients. Br. J. Cancer 98, 489-495.
    • (2008) Br. J. Cancer , vol.98 , pp. 489-495
    • Blechschmidt, K.1    Sassen, S.2    Schmalfeldt, B.3    Schuster, T.4    Höfler, H.5    Becker, K.F.6
  • 11
    • 77956230322 scopus 로고    scopus 로고
    • The ZEB/miR-200 feedback loop-a motor of cellular plasticity in development and cancer?
    • Brabletz, S., and Brabletz, T. (2010). The ZEB/miR-200 feedback loop-a motor of cellular plasticity in development and cancer? EMBO Rep. 11, 670-677.
    • (2010) EMBO Rep. , vol.11 , pp. 670-677
    • Brabletz, S.1    Brabletz, T.2
  • 12
    • 77950502330 scopus 로고    scopus 로고
    • ZEB proteins link cell motility with cell cycle control and cell survival in cancer
    • Browne, G., Sayan, A. E., and Tulchinsky, E. (2010). ZEB proteins link cell motility with cell cycle control and cell survival in cancer. Cell Cycle 9, 886-891.
    • (2010) Cell Cycle , vol.9 , pp. 886-891
    • Browne, G.1    Sayan, A.E.2    Tulchinsky, E.3
  • 13
    • 19744368302 scopus 로고    scopus 로고
    • Cancer of the ovary
    • Cannistra, S. A. (2004). Cancer of the ovary. N. Engl. J. Med. 351, 2519-2529.
    • (2004) N. Engl. J. Med. , vol.351 , pp. 2519-2529
    • Cannistra, S.A.1
  • 14
    • 84861344069 scopus 로고    scopus 로고
    • Tissue transglutaminase links TGF-β, epithelial to mesenchymal transition and a stem cell phenotype in ovarian cancer
    • doi:10.1038/onc.2011.429. [Epub ahead of print]
    • Cao, L., Shao, M., Schilder, J., Guise, T., Mohammad, K. S., and Matei, D. (2012). Tissue transglutaminase links TGF-β, epithelial to mesenchymal transition and a stem cell phenotype in ovarian cancer. Oncogene. doi:10.1038/onc.2011.429. [Epub ahead of print].
    • (2012) Oncogene.
    • Cao, L.1    Shao, M.2    Schilder, J.3    Guise, T.4    Mohammad, K.S.5    Matei, D.6
  • 16
    • 1042267263 scopus 로고    scopus 로고
    • Cell adhesion and signalling by cadherins and Ig-CAMs in cancer
    • Cavallaro, U., and Christofori, G. (2004). Cell adhesion and signalling by cadherins and Ig-CAMs in cancer. Nat. Rev. Cancer 4, 118-132.
    • (2004) Nat. Rev. Cancer , vol.4 , pp. 118-132
    • Cavallaro, U.1    Christofori, G.2
  • 18
    • 79952815913 scopus 로고    scopus 로고
    • Overexpression of miR-429 induces mesenchymal-to-epithelial transition (MET) in metastatic ovarian cancer cells
    • Chen, J., Wang, L., Matyunina, L. V., Hill, C. G., and McDonald, J. F. (2011). Overexpression of miR-429 induces mesenchymal-to-epithelial transition (MET) in metastatic ovarian cancer cells. Gynecol. Oncol. 121, 200-205.
    • (2011) Gynecol. Oncol. , vol.121 , pp. 200-205
    • Chen, J.1    Wang, L.2    Matyunina, L.V.3    Hill, C.G.4    McDonald, J.F.5
  • 19
    • 77954996742 scopus 로고    scopus 로고
    • Hydrogen peroxide mediates EGF-induced down-regulation of E-cadherin expression via p38 MAPK and snail in human ovarian cancer cells
    • Cheng, J. C., Klausen, C., and Leung, P. C. (2010). Hydrogen peroxide mediates EGF-induced down-regulation of E-cadherin expression via p38 MAPK and snail in human ovarian cancer cells. Mol. Endocrinol. 24, 1569-1580.
    • (2010) Mol. Endocrinol. , vol.24 , pp. 1569-1580
    • Cheng, J.C.1    Klausen, C.2    Leung, P.C.3
  • 22
    • 79952704437 scopus 로고    scopus 로고
    • Downregulation of cell surface CA125/MUC16 induces epithelial-to-mesenchymal transition and restores EGFR signalling in NIH:OVCAR3 ovarian carcinoma cells
    • Comamala, M., Pinard, M., Thériault, C., Matte, I., Albert, A., Boivin, M., Beaudin, J., Piché, A., and Rancourt, C. (2011). Downregulation of cell surface CA125/MUC16 induces epithelial-to-mesenchymal transition and restores EGFR signalling in NIH:OVCAR3 ovarian carcinoma cells. Br. J. Cancer 104, 989-999.
    • (2011) Br. J. Cancer , vol.104 , pp. 989-999
    • Comamala, M.1    Pinard, M.2    Thériault, C.3    Matte, I.4    Albert, A.5    Boivin, M.6    Beaudin, J.7    Piché, A.8    Rancourt, C.9
  • 23
    • 0029099138 scopus 로고
    • Central nervous system metastases in patients with ovarian carcinoma. A report of 23 cases and literature review
    • Cormio, G., Maneo, A., Parma, G., Pittelli, M. R., Miceli, M. D., and Bonazzi, C. (1995). Central nervous system metastases in patients with ovarian carcinoma. A report of 23 cases and literature review. Ann. Oncol. 6, 571-574.
    • (1995) Ann. Oncol. , vol.6 , pp. 571-574
    • Cormio, G.1    Maneo, A.2    Parma, G.3    Pittelli, M.R.4    Miceli, M.D.5    Bonazzi, C.6
  • 24
    • 70350728790 scopus 로고    scopus 로고
    • The epidermal growth factor receptor responsive miR-125a represses mesenchymal morphology in ovarian cancer cells
    • Cowden Dahl, K. D., Dahl, R., Kruichak, J. N., and Hudson, L. G. (2009). The epidermal growth factor receptor responsive miR-125a represses mesenchymal morphology in ovarian cancer cells. Neoplasia 11, 1208-1215.
    • (2009) Neoplasia , vol.11 , pp. 1208-1215
    • Cowden Dahl, K.D.1    Dahl, R.2    Kruichak, J.N.3    Hudson, L.G.4
  • 26
    • 79960310204 scopus 로고    scopus 로고
    • Claudin-7 is frequently overexpressed in ovarian cancer and promotes invasion
    • doi:10.1371/journal.pone.0022119
    • Dahiya, N., Becker, K. G., Wood, W. H. III, Zhang, Y., and Morin, P. J. (2011). Claudin-7 is frequently overexpressed in ovarian cancer and promotes invasion. PLoS ONE 6, e22119. doi:10.1371/journal.pone.0022119
    • (2011) PLoS ONE , vol.6
    • Dahiya, N.1    Becker, K.G.2    Wood III, W.H.3    Zhang, Y.4    Morin, P.J.5
  • 27
    • 58149145772 scopus 로고    scopus 로고
    • The metastasis-associated gene MTA1 is upregulated in advanced ovarian cancer, represses ERbeta, and enhances expression of oncogenic cytokine GRO
    • Dannenmann, C., Shabani, N., Friese, K., Jeschke, U., Mylonas, I., and Brüning, A. (2008). The metastasis-associated gene MTA1 is upregulated in advanced ovarian cancer, represses ERbeta, and enhances expression of oncogenic cytokine GRO. Cancer Biol. Ther. 7, 1460-1467.
    • (2008) Cancer Biol. Ther. , vol.7 , pp. 1460-1467
    • Dannenmann, C.1    Shabani, N.2    Friese, K.3    Jeschke, U.4    Mylonas, I.5    Brüning, A.6
  • 28
    • 0030761757 scopus 로고    scopus 로고
    • Expression of cadherins in benign, borderline, and malignant ovarian epithelial tumors: a clinicopathologic study of 60 cases
    • Darai, E., Scoazec, J. Y., Walker-Combrouze, F., Mlika-Cabanne, N., Feldmann, G., Madelenat, P., and Potet, F. (1997). Expression of cadherins in benign, borderline, and malignant ovarian epithelial tumors: a clinicopathologic study of 60 cases. Hum. Pathol. 28, 922-928.
    • (1997) Hum. Pathol. , vol.28 , pp. 922-928
    • Darai, E.1    Scoazec, J.Y.2    Walker-Combrouze, F.3    Mlika-Cabanne, N.4    Feldmann, G.5    Madelenat, P.6    Potet, F.7
  • 29
    • 37049007438 scopus 로고    scopus 로고
    • MUC4 is upregulated in ovarian carcinoma effusions and differentiates carcinoma cells from mesothelial cells
    • Davidson, B., Baekelandt, M., and Shih, I. M. (2007). MUC4 is upregulated in ovarian carcinoma effusions and differentiates carcinoma cells from mesothelial cells. Diagn. Cytopathol. 35, 756-760.
    • (2007) Diagn. Cytopathol. , vol.35 , pp. 756-760
    • Davidson, B.1    Baekelandt, M.2    Shih, I.M.3
  • 30
    • 0033675418 scopus 로고    scopus 로고
    • E-cadherin and alpha-, beta-, and gamma-catenin protein expression is up-regulated in ovarian carcinoma cells in serous effusions
    • Davidson, B., Berner, A., Nesland, J. M., Risberg, B., Berner, H. S., Tropé, C. G., Kristensen, G. B., Bryne, M., and Flørenes, V. A. (2000a). E-cadherin and alpha-, beta-, and gamma-catenin protein expression is up-regulated in ovarian carcinoma cells in serous effusions. J. Pathol. 192, 460-469.
    • (2000) J. Pathol. , vol.192 , pp. 460-469
    • Davidson, B.1    Berner, A.2    Nesland, J.M.3    Risberg, B.4    Berner, H.S.5    Tropé, C.G.6    Kristensen, G.B.7    Bryne, M.8    Flørenes, V.A.9
  • 32
    • 0037386973 scopus 로고    scopus 로고
    • PEA3 is the second Ets family transcription factor involved in tumor progression in ovarian carcinoma
    • Davidson, B., Goldberg, I., Gotlieb, W. H., Kopolovic, J., Ben-Baruch, G., and Reich, R. (2003). PEA3 is the second Ets family transcription factor involved in tumor progression in ovarian carcinoma. Clin. Cancer Res. 9, 1412-1419.
    • (2003) Clin. Cancer Res. , vol.9 , pp. 1412-1419
    • Davidson, B.1    Goldberg, I.2    Gotlieb, W.H.3    Kopolovic, J.4    Ben-Baruch, G.5    Reich, R.6
  • 34
    • 33750691679 scopus 로고    scopus 로고
    • Gene expression signatures differentiate ovarian/peritoneal serous carcinoma from diffuse malignant peritoneal mesothelioma
    • Davidson, B., Zhang, Z., Kleinberg, L., Li, M., Flørenes, V. A., Wang, T. L., and Shih, I. M. (2006). Gene expression signatures differentiate ovarian/peritoneal serous carcinoma from diffuse malignant peritoneal mesothelioma. Clin. Cancer Res. 12, 5944-5950.
    • (2006) Clin. Cancer Res. , vol.12 , pp. 5944-5950
    • Davidson, B.1    Zhang, Z.2    Kleinberg, L.3    Li, M.4    Flørenes, V.A.5    Wang, T.L.6    Shih, I.M.7
  • 35
    • 33750167087 scopus 로고    scopus 로고
    • The reinforcement of invasion in epithelial ovarian cancer cells by 17 beta-estradiol is associated with up-regulation of Snail
    • Ding, J. X., Feng, Y. J., Yao, L. Q., Yu, M., Jin, H. Y., and Yin, L. H. (2006). The reinforcement of invasion in epithelial ovarian cancer cells by 17 beta-estradiol is associated with up-regulation of Snail. Gynecol. Oncol. 103, 623-630.
    • (2006) Gynecol. Oncol. , vol.103 , pp. 623-630
    • Ding, J.X.1    Feng, Y.J.2    Yao, L.Q.3    Yu, M.4    Jin, H.Y.5    Yin, L.H.6
  • 36
    • 16844368863 scopus 로고    scopus 로고
    • Snail, Slug, and Smad-interacting protein 1 as novel parameters of disease aggressiveness in metastatic ovarian and breast carcinoma
    • Elloul, S., Elstrand, M. B., Nesland, J. M., Tropé, C. G., Kvalheim, G., Goldberg, I., Reich, R., and Davidson, B. (2005). Snail, Slug, and Smad-interacting protein 1 as novel parameters of disease aggressiveness in metastatic ovarian and breast carcinoma. Cancer 103, 1631-1643.
    • (2005) Cancer , vol.103 , pp. 1631-1643
    • Elloul, S.1    Elstrand, M.B.2    Nesland, J.M.3    Tropé, C.G.4    Kvalheim, G.5    Goldberg, I.6    Reich, R.7    Davidson, B.8
  • 38
    • 77950866305 scopus 로고    scopus 로고
    • Mesenchymal-to-epithelial transition determinants as characteristics of ovarian carcinoma effusions
    • Elloul, S., Vaksman, O., Stavnes, H. T., Tropé, C. G., Davidson, B., and Reich, R. (2010). Mesenchymal-to-epithelial transition determinants as characteristics of ovarian carcinoma effusions. Clin. Exp. Metastasis 27, 161-172.
    • (2010) Clin. Exp. Metastasis , vol.27 , pp. 161-172
    • Elloul, S.1    Vaksman, O.2    Stavnes, H.T.3    Tropé, C.G.4    Davidson, B.5    Reich, R.6
  • 39
    • 6944238451 scopus 로고    scopus 로고
    • Prognostic value of E-cadherin immunoexpression in patients with primary ovarian carcinomas
    • Faleiro-Rodrigues, C., Macedo-Pinto, I., Pereira, D., and Lopes, C. S. (2004). Prognostic value of E-cadherin immunoexpression in patients with primary ovarian carcinomas. Ann. Oncol. 15, 1535-1542.
    • (2004) Ann. Oncol. , vol.15 , pp. 1535-1542
    • Faleiro-Rodrigues, C.1    Macedo-Pinto, I.2    Pereira, D.3    Lopes, C.S.4
  • 41
    • 0015385809 scopus 로고
    • The role of lymphatic obstruction in the formation of ascites in a murine ovarian carcinoma
    • Feldman, G. B., Knapp, R. C., Order, S. E., and Hellman, S. (1972). The role of lymphatic obstruction in the formation of ascites in a murine ovarian carcinoma. Cancer Res. 32, 1663-1666.
    • (1972) Cancer Res. , vol.32 , pp. 1663-1666
    • Feldman, G.B.1    Knapp, R.C.2    Order, S.E.3    Hellman, S.4
  • 42
    • 38349169664 scopus 로고    scopus 로고
    • Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight?
    • Filipowicz, W., Bhattacharyya, S. N., and Sonenberg, N. (2008). Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight? Nat. Rev. Genet. 9, 102-114.
    • (2008) Nat. Rev. Genet. , vol.9 , pp. 102-114
    • Filipowicz, W.1    Bhattacharyya, S.N.2    Sonenberg, N.3
  • 43
    • 79952326788 scopus 로고    scopus 로고
    • Redundant or separate entities?-roles of Twist1 and Twist2 as molecular switches during gene transcription
    • doi:10.1186/1471-2407-6-186
    • Franco, H. L., Casasnovas, J., Rodríguez-Medina, J. R., and Cadilla, C. L. (2011). Redundant or separate entities?-roles of Twist1 and Twist2 as molecular switches during gene transcription. Nucleic Acids Res. 39, 1177-1186. doi:10.1186/1471-2407-6-186
    • (2011) Nucleic Acids Res. , vol.39 , pp. 1177-1186
    • Franco, H.L.1    Casasnovas, J.2    Rodríguez-Medina, J.R.3    Cadilla, C.L.4
  • 44
    • 79952273248 scopus 로고    scopus 로고
    • C terminus of Clostridium perfringens enterotoxin downregulates CLDN4 and sensitizes ovarian cancer cells to Taxol and Carboplatin
    • Gao, Z., Xu, X., McClane, B., Zeng, Q., Litkouhi, B., Welch, W. R., Berkowitz, R. S., Mok, S. C., and Garner, E. I. (2011). C terminus of Clostridium perfringens enterotoxin downregulates CLDN4 and sensitizes ovarian cancer cells to Taxol and Carboplatin. Clin. Cancer Res. 17, 1065-1074.
    • (2011) Clin. Cancer Res. , vol.17 , pp. 1065-1074
    • Gao, Z.1    Xu, X.2    McClane, B.3    Zeng, Q.4    Litkouhi, B.5    Welch, W.R.6    Berkowitz, R.S.7    Mok, S.C.8    Garner, E.I.9
  • 47
    • 77950188189 scopus 로고    scopus 로고
    • Pathway analysis of gene lists associated with platinum-based chemotherapy resistance in ovarian cancer: the big picture
    • Helleman, J., Smid, M., Jansen, M. P., van der Burg, M. E., and Berns, E. M. (2010). Pathway analysis of gene lists associated with platinum-based chemotherapy resistance in ovarian cancer: the big picture. Gynecol. Oncol. 117, 170-176.
    • (2010) Gynecol. Oncol. , vol.117 , pp. 170-176
    • Helleman, J.1    Smid, M.2    Jansen, M.P.3    van der Burg, M.E.4    Berns, E.M.5
  • 48
    • 0034680368 scopus 로고    scopus 로고
    • Snail/Slug family of repressors: slowly going into the fast lane of development and cancer
    • Hemavathy, K., Ashraf, S. I., and Ip, Y. T. (2000). Snail/Slug family of repressors: slowly going into the fast lane of development and cancer. Gene 257, 1-12.
    • (2000) Gene , vol.257 , pp. 1-12
    • Hemavathy, K.1    Ashraf, S.I.2    Ip, Y.T.3
  • 50
    • 33847127375 scopus 로고    scopus 로고
    • The claudin gene family: expression in normal and neoplastic tissues
    • Hewitt, K. J., Agarwal, R., and Morin, P. J. (2006). The claudin gene family: expression in normal and neoplastic tissues. BMC Cancer 6, 186.
    • (2006) BMC Cancer , vol.6 , pp. 186
    • Hewitt, K.J.1    Agarwal, R.2    Morin, P.J.3
  • 53
    • 0014946424 scopus 로고
    • The genesis of ascites in ovarian cancer
    • Hirabayashi, K., and Graham, J. (1970). The genesis of ascites in ovarian cancer. Am. J. Obstet. Gynecol. 106, 492-497.
    • (1970) Am. J. Obstet. Gynecol. , vol.106 , pp. 492-497
    • Hirabayashi, K.1    Graham, J.2
  • 54
    • 33846550531 scopus 로고    scopus 로고
    • Expression of Twist increases the risk for recurrence and for poor survival in epithelial ovarian carcinoma patients
    • Hosono, S., Kajiyama, H., Terauchi, M., Shibata, K., Ino, K., Nawa, A., and Kikkawa, F. (2007). Expression of Twist increases the risk for recurrence and for poor survival in epithelial ovarian carcinoma patients. Br. J. Cancer 96, 314-320.
    • (2007) Br. J. Cancer , vol.96 , pp. 314-320
    • Hosono, S.1    Kajiyama, H.2    Terauchi, M.3    Shibata, K.4    Ino, K.5    Nawa, A.6    Kikkawa, F.7
  • 56
    • 47549085187 scopus 로고    scopus 로고
    • Phenotypic plasticity of neoplastic ovarian epithelium: unique cadherin profiles in tumor progression
    • Hudson, L. G., Zeineldin, R., and Stack, M. S. (2008). Phenotypic plasticity of neoplastic ovarian epithelium: unique cadherin profiles in tumor progression. Clin. Exp. Metastasis 25, 643-655.
    • (2008) Clin. Exp. Metastasis , vol.25 , pp. 643-655
    • Hudson, L.G.1    Zeineldin, R.2    Stack, M.S.3
  • 57
    • 54949147234 scopus 로고    scopus 로고
    • Expression of the ZEB1 (deltaEF1) transcription factor in human: additional insights
    • Hurt, E. M., Saykally, J. N., Anose, B. M., Kalli, K. R., and Sanders, M. M. (2008). Expression of the ZEB1 (deltaEF1) transcription factor in human: additional insights. Mol. Cell. Biochem. 318, 89-99.
    • (2008) Mol. Cell. Biochem. , vol.318 , pp. 89-99
    • Hurt, E.M.1    Saykally, J.N.2    Anose, B.M.3    Kalli, K.R.4    Sanders, M.M.5
  • 58
    • 77956945067 scopus 로고    scopus 로고
    • BRCA1-associated epigenetic regulation of p73 mediates an effector pathway for chemosensitivity in ovarian carcinoma
    • Ibrahim, N., He, L., Leong, C. O., Xing, D., Karlan, B. Y., Swisher, E. M., Rueda, B. R., Orsulic, S., and Ellisen, L. W. (2010). BRCA1-associated epigenetic regulation of p73 mediates an effector pathway for chemosensitivity in ovarian carcinoma. Cancer Res. 70, 7155-7165.
    • (2010) Cancer Res. , vol.70 , pp. 7155-7165
    • Ibrahim, N.1    He, L.2    Leong, C.O.3    Xing, D.4    Karlan, B.Y.5    Swisher, E.M.6    Rueda, B.R.7    Orsulic, S.8    Ellisen, L.W.9
  • 59
    • 0141760411 scopus 로고    scopus 로고
    • Hypoxia attenuates the expression of E-cadherin via up-regulation of SNAIL in ovarian carcinoma cells
    • Imai, T., Horiuchi, A., Wang, C., Oka, K., Ohira, S., Nikaido, T., and Konishi, I. (2003). Hypoxia attenuates the expression of E-cadherin via up-regulation of SNAIL in ovarian carcinoma cells. Am. J. Pathol. 163, 1437-1447.
    • (2003) Am. J. Pathol. , vol.163 , pp. 1437-1447
    • Imai, T.1    Horiuchi, A.2    Wang, C.3    Oka, K.4    Ohira, S.5    Nikaido, T.6    Konishi, I.7
  • 60
  • 62
    • 35148825636 scopus 로고    scopus 로고
    • Chemoresistance to paclitaxel induces epithelial-mesenchymal transition and enhances metastatic potential for epithelial ovarian carcinoma cells
    • Kajiyama, H., Shibata, K., Terauchi, M., Yamashita, M., Ino, K., Nawa, A., and Kikkawa, F. (2007). Chemoresistance to paclitaxel induces epithelial-mesenchymal transition and enhances metastatic potential for epithelial ovarian carcinoma cells. Int. J. Oncol. 31, 277-283.
    • (2007) Int. J. Oncol. , vol.31 , pp. 277-283
    • Kajiyama, H.1    Shibata, K.2    Terauchi, M.3    Yamashita, M.4    Ino, K.5    Nawa, A.6    Kikkawa, F.7
  • 63
    • 67650999875 scopus 로고    scopus 로고
    • The basics of epithelial-mesenchymal transition
    • Kalluri, R., and Weinberg, R. A. (2009). The basics of epithelial-mesenchymal transition. J. Clin. Invest. 119, 1420-1428.
    • (2009) J. Clin. Invest. , vol.119 , pp. 1420-1428
    • Kalluri, R.1    Weinberg, R.A.2
  • 66
    • 42949113594 scopus 로고    scopus 로고
    • Claudin upregulation in ovarian carcinoma effusions is associated with poor survival
    • Kleinberg, L., Holth, A., Trope', C. G., Reich, R., and Davidson, B. (2008). Claudin upregulation in ovarian carcinoma effusions is associated with poor survival. Hum. Pathol. 39, 747-757.
    • (2008) Hum. Pathol. , vol.39 , pp. 747-757
    • Kleinberg, L.1    Holth, A.2    Trope', C.G.3    Reich, R.4    Davidson, B.5
  • 68
    • 15544362735 scopus 로고    scopus 로고
    • Snail and Slug are major determinants of ovarian cancer invasiveness at the transcription level
    • Kurrey, N. K., Amit, K., and Bapat, S. A. (2005). Snail and Slug are major determinants of ovarian cancer invasiveness at the transcription level. Gynecol. Oncol. 97, 155-165.
    • (2005) Gynecol. Oncol. , vol.97 , pp. 155-165
    • Kurrey, N.K.1    Amit, K.2    Bapat, S.A.3
  • 70
    • 78149416513 scopus 로고    scopus 로고
    • Stanniocalcin-2 promotes epithelial-mesenchymal transition and invasiveness in hypoxic human ovarian cancer cells
    • Law, A. Y., and Wong, C. K. (2010). Stanniocalcin-2 promotes epithelial-mesenchymal transition and invasiveness in hypoxic human ovarian cancer cells. Exp. Cell Res. 316, 3425-3434.
    • (2010) Exp. Cell Res. , vol.316 , pp. 3425-3434
    • Law, A.Y.1    Wong, C.K.2
  • 72
    • 73349111961 scopus 로고    scopus 로고
    • Claudin-containing exosomes in the peripheral circulation of women with ovarian cancer
    • doi:10.1186/1471-2407-9-244
    • Li, J., Sherman-Baust, C. A., Tsai-Turton, M., Bristow, R. E., Roden, R. B., and Morin, P. J. (2009a). Claudin-containing exosomes in the peripheral circulation of women with ovarian cancer. BMC Cancer 9, 244. doi:10.1186/1471-2407-9-244
    • (2009) BMC Cancer , vol.9 , pp. 244
    • Li, J.1    Sherman-Baust, C.A.2    Tsai-Turton, M.3    Bristow, R.E.4    Roden, R.B.5    Morin, P.J.6
  • 74
    • 34247359877 scopus 로고    scopus 로고
    • Neutrophil gelatinase-associated lipocalin (NGAL) an early-screening biomarker for ovarian cancer: NGAL is associated with epidermal growth factor-induced epithelio-mesenchymal transition
    • Lim, R., Ahmed, N., Borregaard, N., Riley, C., Wafai, R., Thompson, E. W., Quinn, M. A., and Rice, G. E. (2007). Neutrophil gelatinase-associated lipocalin (NGAL) an early-screening biomarker for ovarian cancer: NGAL is associated with epidermal growth factor-induced epithelio-mesenchymal transition. Int. J. Cancer 120, 2426-2434.
    • (2007) Int. J. Cancer , vol.120 , pp. 2426-2434
    • Lim, R.1    Ahmed, N.2    Borregaard, N.3    Riley, C.4    Wafai, R.5    Thompson, E.W.6    Quinn, M.A.7    Rice, G.E.8
  • 77
    • 70450142560 scopus 로고    scopus 로고
    • Inflammation and EMT: an alliance towards organ fibrosis and cancer progression
    • López-Novoa, J. M., and Nieto, M. A. (2009). Inflammation and EMT: an alliance towards organ fibrosis and cancer progression. EMBO Mol. Med. 1, 303-314.
    • (2009) EMBO Mol. Med. , vol.1 , pp. 303-314
    • López-Novoa, J.M.1    Nieto, M.A.2
  • 79
    • 77952009538 scopus 로고    scopus 로고
    • HMGA2: a biomarker significantly over-expressed in high grade ovarian serous carcinoma
    • Mahajan, A., Liu, Z., Gellert, L., Zou, X., Yang, G., Lee, P., Yang, X., and Wei, J. J. (2010). HMGA2: a biomarker significantly over-expressed in high grade ovarian serous carcinoma. Mod. Pathol. 23, 673-681.
    • (2010) Mod. Pathol. , vol.23 , pp. 673-681
    • Mahajan, A.1    Liu, Z.2    Gellert, L.3    Zou, X.4    Yang, G.5    Lee, P.6    Yang, X.7    Wei, J.J.8
  • 80
    • 84857613435 scopus 로고    scopus 로고
    • aV integrins and TGF-β induced EMT; a circle of regulation
    • Mamuya, F. A., and Duncan, M. K. (2012). aV integrins and TGF-β induced EMT; a circle of regulation. J. Cell Mol. Med. 16, 445-455.
    • (2012) J. Cell Mol. Med. , vol.16 , pp. 445-455
    • Mamuya, F.A.1    Duncan, M.K.2
  • 82
    • 0033582334 scopus 로고    scopus 로고
    • Claudin multigene family encoding four-transmembrane domain protein components of tight junction strands
    • Morita, K., Furuse, M., Fujimoto, K., and Tsukita, S. (1999). Claudin multigene family encoding four-transmembrane domain protein components of tight junction strands. Proc. Natl. Acad. Sci. U.S.A. 96, 511-516.
    • (1999) Proc. Natl. Acad. Sci. U.S.A. , vol.96 , pp. 511-516
    • Morita, K.1    Furuse, M.2    Fujimoto, K.3    Tsukita, S.4
  • 83
    • 0028834106 scopus 로고
    • Pathogenesis of ascites tumor growth: vascular permeability factor, vascular hyperpermeability, and ascites tumor accumulation
    • Nagy, J. A., Masse, E. M., Herzberg, K. T., Meyers, M. S., Yeo, K. T., Yeo, T. K., Sioussat, T. M., and Dvorak, H. F. (1995). Pathogenesis of ascites tumor growth: vascular permeability factor, vascular hyperpermeability, and ascites tumor accumulation. Cancer Res. 55, 360-368.
    • (1995) Cancer Res. , vol.55 , pp. 360-368
    • Nagy, J.A.1    Masse, E.M.2    Herzberg, K.T.3    Meyers, M.S.4    Yeo, K.T.5    Yeo, T.K.6    Sioussat, T.M.7    Dvorak, H.F.8
  • 84
    • 57749086300 scopus 로고    scopus 로고
    • MicroRNAs and cancer: past, present, and potential future
    • Nelson, K. M., and Weiss, G. J. (2008). MicroRNAs and cancer: past, present, and potential future. Mol. Cancer Ther. 7, 3655-3660.
    • (2008) Mol. Cancer Ther. , vol.7 , pp. 3655-3660
    • Nelson, K.M.1    Weiss, G.J.2
  • 85
    • 0036513626 scopus 로고    scopus 로고
    • The snail superfamily of zinc-finger transcription factors
    • Nieto, M. A. (2002). The snail superfamily of zinc-finger transcription factors. Nat. Rev. Mol. Cell Biol. 3, 155-166.
    • (2002) Nat. Rev. Mol. Cell Biol. , vol.3 , pp. 155-166
    • Nieto, M.A.1
  • 86
    • 50649124650 scopus 로고    scopus 로고
    • Estrogen regulates Snail and Slug in the down-regulation of E-cadherin and induces metastatic potential of ovarian cancer cells through estrogen receptor alpha
    • Park, S. H., Cheung, L. W., Wong, A. S., and Leung, P. C. (2008a). Estrogen regulates Snail and Slug in the down-regulation of E-cadherin and induces metastatic potential of ovarian cancer cells through estrogen receptor alpha. Mol. Endocrinol. 22, 2085-2098.
    • (2008) Mol. Endocrinol. , vol.22 , pp. 2085-2098
    • Park, S.H.1    Cheung, L.W.2    Wong, A.S.3    Leung, P.C.4
  • 87
    • 41649091906 scopus 로고    scopus 로고
    • The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2
    • Park, S. M., Gaur, A. B., Lengyel, E., and Peter, M. E. (2008b). The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2. Genes Dev. 22, 894-907.
    • (2008) Genes Dev. , vol.22 , pp. 894-907
    • Park, S.M.1    Gaur, A.B.2    Lengyel, E.3    Peter, M.E.4
  • 89
    • 2942548177 scopus 로고    scopus 로고
    • Tumor suppressor gene E-cadherin and its role in normal and malignant cells
    • Pecina-Slaus, N. (2003). Tumor suppressor gene E-cadherin and its role in normal and malignant cells. Cancer Cell Int. 3, 17.
    • (2003) Cancer Cell Int. , vol.3 , pp. 17
    • Pecina-Slaus, N.1
  • 90
    • 34249289041 scopus 로고    scopus 로고
    • Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype?
    • Peinado, H., Olmeda, D., and Cano, A. (2007). Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype? Nat. Rev. Cancer 7, 415-428.
    • (2007) Nat. Rev. Cancer , vol.7 , pp. 415-428
    • Peinado, H.1    Olmeda, D.2    Cano, A.3
  • 91
    • 53049108469 scopus 로고    scopus 로고
    • p70 S6 kinase promotes epithelial to mesenchymal transition through snail induction in ovarian cancer cells
    • Pon, Y. L., Zhou, H. Y., Cheung, A. N., Ngan, H. Y., and Wong, A. S. (2008). p70 S6 kinase promotes epithelial to mesenchymal transition through snail induction in ovarian cancer cells. Cancer Res. 68, 6524-6532.
    • (2008) Cancer Res. , vol.68 , pp. 6524-6532
    • Pon, Y.L.1    Zhou, H.Y.2    Cheung, A.N.3    Ngan, H.Y.4    Wong, A.S.5
  • 92
    • 77958451128 scopus 로고    scopus 로고
    • MUC4 mucin-induced epithelial to mesenchymal transition: a novel mechanism for metastasis of human ovarian cancer cells
    • Ponnusamy, M. P., Lakshmanan, I., Jain, M., Das, S., Chakraborty, S., Dey, P., and Batra, S. K. (2010). MUC4 mucin-induced epithelial to mesenchymal transition: a novel mechanism for metastasis of human ovarian cancer cells. Oncogene 29, 5741-5754.
    • (2010) Oncogene , vol.29 , pp. 5741-5754
    • Ponnusamy, M.P.1    Lakshmanan, I.2    Jain, M.3    Das, S.4    Chakraborty, S.5    Dey, P.6    Batra, S.K.7
  • 93
    • 84860336909 scopus 로고    scopus 로고
    • Ovarian carcinomas: five distinct diseases with different origins, genetic alterations, and clinicopathological features
    • Prat, J. (2012). Ovarian carcinomas: five distinct diseases with different origins, genetic alterations, and clinicopathological features. Virchows Arch. 460, 237-249.
    • (2012) Virchows Arch. , vol.460 , pp. 237-249
    • Prat, J.1
  • 94
    • 85027921689 scopus 로고    scopus 로고
    • The cadherin switch in ovarian high-grade serous carcinoma is associated with disease progression
    • Quattrocchi, L., Green, A. R., Martin, S., Durrant, L., and Deen, S. (2011). The cadherin switch in ovarian high-grade serous carcinoma is associated with disease progression. Virchows Arch. 459, 21-29.
    • (2011) Virchows Arch. , vol.459 , pp. 21-29
    • Quattrocchi, L.1    Green, A.R.2    Martin, S.3    Durrant, L.4    Deen, S.5
  • 95
    • 67649381830 scopus 로고    scopus 로고
    • Development and characterization of a human single-chain antibody fragment against claudin-3: a novel therapeutic target in ovarian and uterine carcinomas
    • Romani, C., Comper, F., Bandiera, E., Ravaggi, A., Bignotti, E., Tassi, R. A., Pecorelli, S., and Santin, A. D. (2009). Development and characterization of a human single-chain antibody fragment against claudin-3: a novel therapeutic target in ovarian and uterine carcinomas. Am. J. Obstet. Gynecol. 201, 70.e1-70.e9.
    • (2009) Am. J. Obstet. Gynecol. , vol.201
    • Romani, C.1    Comper, F.2    Bandiera, E.3    Ravaggi, A.4    Bignotti, E.5    Tassi, R.A.6    Pecorelli, S.7    Santin, A.D.8
  • 96
    • 79954627096 scopus 로고    scopus 로고
    • Acquisition of chemoresistance and EMT phenotype is linked with activation of the endothelin A receptor pathway in ovarian carcinoma cells
    • Rosanò, L., Cianfrocca, R., Spinella, F., Di Castro, V., Nicotra, M. R., Lucidi, A., Ferrandina, G., Natali, P. G., and Bagnato, A. (2011). Acquisition of chemoresistance and EMT phenotype is linked with activation of the endothelin A receptor pathway in ovarian carcinoma cells. Clin. Cancer Res. 17, 2350-2360.
    • (2011) Clin. Cancer Res. , vol.17 , pp. 2350-2360
    • Rosanò, L.1    Cianfrocca, R.2    Spinella, F.3    Di Castro, V.4    Nicotra, M.R.5    Lucidi, A.6    Ferrandina, G.7    Natali, P.G.8    Bagnato, A.9
  • 99
    • 0031127765 scopus 로고    scopus 로고
    • Relationship between pelvic lymph node involvement and other disease sites in patients with ovarian cancer
    • Sakai, K., Kamura, T., Hirakawa, T., Saito, T., Kaku, T., and Nakano, H. (1997). Relationship between pelvic lymph node involvement and other disease sites in patients with ovarian cancer. Gynecol. Oncol. 65, 164-168.
    • (1997) Gynecol. Oncol. , vol.65 , pp. 164-168
    • Sakai, K.1    Kamura, T.2    Hirakawa, T.3    Saito, T.4    Kaku, T.5    Nakano, H.6
  • 100
    • 81155124248 scopus 로고    scopus 로고
    • Potential applications of microRNAs in cancer diagnosis, prognosis, and treatment
    • Sandhu, S., and Garzon, R. (2011). Potential applications of microRNAs in cancer diagnosis, prognosis, and treatment. Semin. Oncol. 38, 781-787.
    • (2011) Semin. Oncol. , vol.38 , pp. 781-787
    • Sandhu, S.1    Garzon, R.2
  • 102
    • 73649115337 scopus 로고    scopus 로고
    • Epithelial-to-mesenchymal transition and ovarian tumor progression induced by tissue transglutaminase
    • Shao, M., Cao, L., Shen, C., Satpathy, M., Chelladurai, B., Bigsby, R. M., Nakshatri, H., and Matei, D. (2009). Epithelial-to-mesenchymal transition and ovarian tumor progression induced by tissue transglutaminase. Cancer Res. 69, 9192-9201.
    • (2009) Cancer Res. , vol.69 , pp. 9192-9201
    • Shao, M.1    Cao, L.2    Shen, C.3    Satpathy, M.4    Chelladurai, B.5    Bigsby, R.M.6    Nakshatri, H.7    Matei, D.8
  • 104
    • 33751171065 scopus 로고    scopus 로고
    • Cadherin expression in ovarian carcinoma and malignant mesothelioma cell effusions
    • Sivertsen, S., Berner, A., Michael, C. W., Bedrossian, C., and Davidson, B. (2006). Cadherin expression in ovarian carcinoma and malignant mesothelioma cell effusions. Acta Cytol. 50, 603-607.
    • (2006) Acta Cytol. , vol.50 , pp. 603-607
    • Sivertsen, S.1    Berner, A.2    Michael, C.W.3    Bedrossian, C.4    Davidson, B.5
  • 105
    • 77954445464 scopus 로고    scopus 로고
    • Epigenetic silencing of SFRP5 is related to malignant phenotype and chemoresistance of ovarian cancer through Wnt signaling pathway
    • Su, H. Y., Lai, H. C., Lin, Y. W., Liu, C. Y., Chen, C. K., Chou, Y. C., Lin, S. P., Lin, W. C., Lee, H. Y., and Yu, M. H. (2010). Epigenetic silencing of SFRP5 is related to malignant phenotype and chemoresistance of ovarian cancer through Wnt signaling pathway. Int. J. Cancer 127, 555-567.
    • (2010) Int. J. Cancer , vol.127 , pp. 555-567
    • Su, H.Y.1    Lai, H.C.2    Lin, Y.W.3    Liu, C.Y.4    Chen, C.K.5    Chou, Y.C.6    Lin, S.P.7    Lin, W.C.8    Lee, H.Y.9    Yu, M.H.10
  • 106
  • 110
    • 34447319929 scopus 로고    scopus 로고
    • BMP4 induces EMT and Rho GTPase activation in human ovarian cancer cells
    • Thériault, B. L., Shepherd, T. G., Mujoomdar, M. L., and Nachtigal, M. W. (2007). BMP4 induces EMT and Rho GTPase activation in human ovarian cancer cells. Carcinogenesis 28, 1153-1162.
    • (2007) Carcinogenesis , vol.28 , pp. 1153-1162
    • Thériault, B.L.1    Shepherd, T.G.2    Mujoomdar, M.L.3    Nachtigal, M.W.4
  • 111
    • 0036595629 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transitions in tumour progression
    • Thiery, J. P. (2002). Epithelial-mesenchymal transitions in tumour progression. Nat. Rev. Cancer 2, 442-454.
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 442-454
    • Thiery, J.P.1
  • 112
    • 70450198396 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transitions in development and disease
    • Thiery, J. P., Acloque, H., Huang, R. Y., and Nieto, M. A. (2009). Epithelial-mesenchymal transitions in development and disease. Cell 139, 871-890.
    • (2009) Cell , vol.139 , pp. 871-890
    • Thiery, J.P.1    Acloque, H.2    Huang, R.Y.3    Nieto, M.A.4
  • 114
    • 79955758096 scopus 로고    scopus 로고
    • Sema3E/plexin-D1 mediated epithelial-to-mesenchymal transition in ovarian endometrioid cancer
    • doi:10.1371/journal.pone.0019396
    • Tseng, C. H., Murray, K. D., Jou, M. F., Hsu, S. M., Cheng, H. J., and Huang, P. H. (2011). Sema3E/plexin-D1 mediated epithelial-to-mesenchymal transition in ovarian endometrioid cancer. PLoS ONE 6, e19396. doi:10.1371/journal.pone.0019396
    • (2011) PLoS ONE , vol.6
    • Tseng, C.H.1    Murray, K.D.2    Jou, M.F.3    Hsu, S.M.4    Cheng, H.J.5    Huang, P.H.6
  • 116
    • 0027212636 scopus 로고
    • Relationship between paraaortic lymph node involvement and intraperitoneal spread in patients with ovarian cancer-a multivariate analysis
    • Tsuruchi, N., Kamura, T., Tsukamoto, N., Akazawa, K., Saito, T., Kaku, T., To, N., and Nakano, H. (1993). Relationship between paraaortic lymph node involvement and intraperitoneal spread in patients with ovarian cancer-a multivariate analysis. Gynecol. Oncol. 49, 51-55.
    • (1993) Gynecol. Oncol. , vol.49 , pp. 51-55
    • Tsuruchi, N.1    Kamura, T.2    Tsukamoto, N.3    Akazawa, K.4    Saito, T.5    Kaku, T.6    To, N.7    Nakano, H.8
  • 117
    • 70049095113 scopus 로고    scopus 로고
    • Nuclear expression of Snail1 in borderline and malignant epithelial ovarian tumours is associated with tumour progression
    • doi:10.1186/1471-2407-9-289
    • Tuhkanen, H., Soini, Y., Kosma, V. M., Anttila, M., Sironen, R., Hämäläinen, K., Kukkonen, L., Virtanen, I., and Mannermaa, A. (2009). Nuclear expression of Snail1 in borderline and malignant epithelial ovarian tumours is associated with tumour progression. BMC Cancer 9, 289. doi:10.1186/1471-2407-9-289
    • (2009) BMC Cancer , vol.9 , pp. 289
    • Tuhkanen, H.1    Soini, Y.2    Kosma, V.M.3    Anttila, M.4    Sironen, R.5    Hämäläinen, K.6    Kukkonen, L.7    Virtanen, I.8    Mannermaa, A.9
  • 118
    • 75149117731 scopus 로고    scopus 로고
    • Claudin-5 overexpression correlates with aggressive behavior in serous ovarian adenocarcinoma
    • Turunen, M., Talvensaari-Mattila, A., Soini, Y., and Santala, M. (2009). Claudin-5 overexpression correlates with aggressive behavior in serous ovarian adenocarcinoma. Anticancer Res. 29, 5185-5189.
    • (2009) Anticancer Res. , vol.29 , pp. 5185-5189
    • Turunen, M.1    Talvensaari-Mattila, A.2    Soini, Y.3    Santala, M.4
  • 120
    • 33645963995 scopus 로고    scopus 로고
    • Claudins and epithelial paracellular transport
    • Van Itallie, C. M., and Anderson, J. M. (2006). Claudins and epithelial paracellular transport. Annu. Rev. Physiol. 68, 403-429.
    • (2006) Annu. Rev. Physiol. , vol.68 , pp. 403-429
    • Van Itallie, C.M.1    Anderson, J.M.2
  • 121
    • 4644245551 scopus 로고    scopus 로고
    • Tumor metastasis: a new twist on epithelial-mesenchymal transitions
    • Vernon, A. E., and LaBonne, C. (2004). Tumor metastasis: a new twist on epithelial-mesenchymal transitions. Curr. Biol. 14, R719-R721.
    • (2004) Curr. Biol. , vol.14
    • Vernon, A.E.1    LaBonne, C.2
  • 122
    • 83055178990 scopus 로고    scopus 로고
    • Silencing of CXCR4 blocks progression of ovarian cancer and depresses canonical Wnt signaling pathway
    • Wang, J., Cai, J., Han, F., Yang, C., Tong, Q., Cao, T., Wu, L., and Wang, Z. (2011). Silencing of CXCR4 blocks progression of ovarian cancer and depresses canonical Wnt signaling pathway. Int. J. Gynecol. Cancer 21, 981-987.
    • (2011) Int. J. Gynecol. Cancer , vol.21 , pp. 981-987
    • Wang, J.1    Cai, J.2    Han, F.3    Yang, C.4    Tong, Q.5    Cao, T.6    Wu, L.7    Wang, Z.8
  • 123
    • 0842286741 scopus 로고    scopus 로고
    • Identification of a novel function of TWIST, a bHLH protein, in the development of acquired taxol resistance in human cancer cells
    • Wang, X., Ling, M. T., Guan, X. Y., Tsao, S. W., Cheung, H. W., Lee, D. T., and Wong, Y. C. (2004). Identification of a novel function of TWIST, a bHLH protein, in the development of acquired taxol resistance in human cancer cells. Oncogene 23, 474-482.
    • (2004) Oncogene , vol.23 , pp. 474-482
    • Wang, X.1    Ling, M.T.2    Guan, X.Y.3    Tsao, S.W.4    Cheung, H.W.5    Lee, D.T.6    Wong, Y.C.7
  • 124
    • 84861409108 scopus 로고    scopus 로고
    • Gab2 regulates the migratory behaviors and E-cadherin expression via activation of the PI3K pathway in ovarian cancer cells
    • doi:10.1038/onc.2011.435. [Epub ahead of print]
    • Wang, Y., Sheng, Q., Spillman, M. A., Behbakht, K., and Gu, H. (2012). Gab2 regulates the migratory behaviors and E-cadherin expression via activation of the PI3K pathway in ovarian cancer cells. Oncogene. doi:10.1038/onc.2011.435. [Epub ahead of print].
    • (2012) Oncogene.
    • Wang, Y.1    Sheng, Q.2    Spillman, M.A.3    Behbakht, K.4    Gu, H.5
  • 125
    • 78751509847 scopus 로고    scopus 로고
    • HMGA2 overexpression-induced ovarian surface epithelial transformation is mediated through regulation of EMT genes
    • Wu, J., Liu, Z., Shao, C., Gong, Y., Hernando, E., Lee, P., Narita, M., Muller, W., Liu, J., and Wei, J. J. (2011). HMGA2 overexpression-induced ovarian surface epithelial transformation is mediated through regulation of EMT genes. Cancer Res. 71, 349-359.
    • (2011) Cancer Res. , vol.71 , pp. 349-359
    • Wu, J.1    Liu, Z.2    Shao, C.3    Gong, Y.4    Hernando, E.5    Lee, P.6    Narita, M.7    Muller, W.8    Liu, J.9    Wei, J.J.10
  • 126
    • 77953571622 scopus 로고    scopus 로고
    • Snail: more than EMT
    • Wu, Y., and Zhou, B. P. (2010). Snail: more than EMT. Cell Adh. Migr. 4, 199-203.
    • (2010) Cell Adh. Migr. , vol.4 , pp. 199-203
    • Wu, Y.1    Zhou, B.P.2
  • 127
    • 77958153789 scopus 로고    scopus 로고
    • TGFβ and EGF synergistically induce a more invasive phenotype of epithelial ovarian cancer cells
    • Xu, Z., Jiang, Y., Steed, H., Davidge, S., and Fu, Y. (2010). TGFβ and EGF synergistically induce a more invasive phenotype of epithelial ovarian cancer cells. Biochem. Biophys. Res. Commun. 401, 376-381.
    • (2010) Biochem. Biophys. Res. Commun. , vol.401 , pp. 376-381
    • Xu, Z.1    Jiang, Y.2    Steed, H.3    Davidge, S.4    Fu, Y.5
  • 128
    • 55749092776 scopus 로고    scopus 로고
    • Heparin-binding epidermal growth factor-like growth factor promotes transcoelomic metastasis in ovarian cancer through epithelial-mesenchymal transition
    • Yagi, H., Yotsumoto, F., and Miyamoto, S. (2008). Heparin-binding epidermal growth factor-like growth factor promotes transcoelomic metastasis in ovarian cancer through epithelial-mesenchymal transition. Mol. Cancer Ther. 7, 3441-3451.
    • (2008) Mol. Cancer Ther. , vol.7 , pp. 3441-3451
    • Yagi, H.1    Yotsumoto, F.2    Miyamoto, S.3
  • 130
    • 77953806998 scopus 로고    scopus 로고
    • TWISTing stemness, inflammation and proliferation of epithelial ovarian cancer cells through MIR199A2/214
    • Yin, G., Chen, R., Alvero, A. B., Fu, H. H., Holmberg, J., Glackin, C., Rutherford, T., and Mor, G. (2010). TWISTing stemness, inflammation and proliferation of epithelial ovarian cancer cells through MIR199A2/214. Oncogene 29, 3545-3553.
    • (2010) Oncogene , vol.29 , pp. 3545-3553
    • Yin, G.1    Chen, R.2    Alvero, A.B.3    Fu, H.H.4    Holmberg, J.5    Glackin, C.6    Rutherford, T.7    Mor, G.8
  • 131
    • 79956104538 scopus 로고    scopus 로고
    • Claudin-4: a potential therapeutic target in chemotherapy-resistant ovarian cancer
    • Yoshida, H., Sumi, T., Zhi, X., Yasui, T., Honda, K., and Ishiko, O. (2011). Claudin-4: a potential therapeutic target in chemotherapy-resistant ovarian cancer. Anticancer Res. 31, 1271-1277.
    • (2011) Anticancer Res. , vol.31 , pp. 1271-1277
    • Yoshida, H.1    Sumi, T.2    Zhi, X.3    Yasui, T.4    Honda, K.5    Ishiko, O.6
  • 132
    • 67650663205 scopus 로고    scopus 로고
    • Changes in the expression of E-cadherin repressors, Snail, Slug, SIP1, and Twist, in the development and progression of ovarian carcinoma: the important role of Snail in ovarian tumorigenesis and progression
    • Yoshida, J., Horiuchi, A., Kikuchi, N., Hayashi, A., Osada, R., Ohira, S., Shiozawa, T., and Konishi, I. (2009a). Changes in the expression of E-cadherin repressors, Snail, Slug, SIP1, and Twist, in the development and progression of ovarian carcinoma: the important role of Snail in ovarian tumorigenesis and progression. Med. Mol. Morphol. 42, 82-91.
    • (2009) Med. Mol. Morphol. , vol.42 , pp. 82-91
    • Yoshida, J.1    Horiuchi, A.2    Kikuchi, N.3    Hayashi, A.4    Osada, R.5    Ohira, S.6    Shiozawa, T.7    Konishi, I.8
  • 134
    • 67651176021 scopus 로고    scopus 로고
    • Recombinant CPE fused to tumor necrosis factor targets human ovarian cancer cells expressing the claudin-3 and claudin-4 receptors
    • Yuan, X., Lin, X., Manorek, G., Kanatani, I., Cheung, L. H., Rosenblum, M. G., and Howell, S. B. (2009). Recombinant CPE fused to tumor necrosis factor targets human ovarian cancer cells expressing the claudin-3 and claudin-4 receptors. Mol. Cancer Ther. 8, 1906-1915.
    • (2009) Mol. Cancer Ther. , vol.8 , pp. 1906-1915
    • Yuan, X.1    Lin, X.2    Manorek, G.3    Kanatani, I.4    Cheung, L.H.5    Rosenblum, M.G.6    Howell, S.B.7
  • 135
    • 84861345772 scopus 로고    scopus 로고
    • Hyperactive EGF receptor, Jaks and Stat3 signaling promote enhanced colony-forming ability, motility and migration of cisplatin-resistant ovarian cancer cells
    • doi:10.1038/onc.2011.409. [Epub ahead of print]
    • Yue, P., Zhang, X., Paladino, D., Sengupta, B., Ahmad, S., Holloway, R. W., Ingersoll, S. B., and Turkson, J. (2012). Hyperactive EGF receptor, Jaks and Stat3 signaling promote enhanced colony-forming ability, motility and migration of cisplatin-resistant ovarian cancer cells. Oncogene. doi:10.1038/onc.2011.409. [Epub ahead of print].
    • (2012) Oncogene.
    • Yue, P.1    Zhang, X.2    Paladino, D.3    Sengupta, B.4    Ahmad, S.5    Holloway, R.W.6    Ingersoll, S.B.7    Turkson, J.8
  • 136
    • 67650996754 scopus 로고    scopus 로고
    • Biomarkers for epithelial-mesenchymal transitions
    • Zeisberg, M., and Neilson, E. G. (2009). Biomarkers for epithelial-mesenchymal transitions. J. Clin. Invest. 119, 1429-1437.
    • (2009) J. Clin. Invest. , vol.119 , pp. 1429-1437
    • Zeisberg, M.1    Neilson, E.G.2
  • 137
    • 78049494838 scopus 로고    scopus 로고
    • Phenotypic plasticity of the ovarian surface epithelium: TGF-beta 1 induction of epithelial to mesenchymal transition (EMT) in vitro
    • Zhu, Y., Nilsson, M., and Sundfeldt, K. (2010). Phenotypic plasticity of the ovarian surface epithelium: TGF-beta 1 induction of epithelial to mesenchymal transition (EMT) in vitro. Endocrinology 151, 5497-5505.
    • (2010) Endocrinology , vol.151 , pp. 5497-5505
    • Zhu, Y.1    Nilsson, M.2    Sundfeldt, K.3
  • 138
    • 34547282613 scopus 로고    scopus 로고
    • Tight junction formation in epithelial ovarian adenocarcinoma
    • Zhu, Y., and Sundfeldt, K. (2007). Tight junction formation in epithelial ovarian adenocarcinoma. Acta Obstet. Gynecol. Scand. 86, 1011-1019.
    • (2007) Acta Obstet. Gynecol. Scand. , vol.86 , pp. 1011-1019
    • Zhu, Y.1    Sundfeldt, K.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.