메뉴 건너뛰기




Volumn 337, Issue 1, 2013, Pages 1-7

Pathogenic role of Epstein-Barr virus latent membrane protein-1 in the development of nasopharyngeal carcinoma

Author keywords

Cancer stem cell; EMT; Epstein Barr virus; LMP1; Nasopharyngeal carcinoma

Indexed keywords

HUMAN HERPESVIRUS 4;

EID: 84880038924     PISSN: 03043835     EISSN: 18727980     Source Type: Journal    
DOI: 10.1016/j.canlet.2013.05.018     Document Type: Review
Times cited : (114)

References (107)
  • 3
    • 0036435166 scopus 로고    scopus 로고
    • Epstein-Barr virus in the pathogenesis of NPC
    • Raab-Traub N. Epstein-Barr virus in the pathogenesis of NPC. Semin. Cancer Biol. 2002, 12:431-441.
    • (2002) Semin. Cancer Biol. , vol.12 , pp. 431-441
    • Raab-Traub, N.1
  • 4
    • 0036063344 scopus 로고    scopus 로고
    • Promotion of metastasis in nasopharyngeal carcinoma by Epstein-Barr virus latent membrane protein-1
    • Yoshizaki T. Promotion of metastasis in nasopharyngeal carcinoma by Epstein-Barr virus latent membrane protein-1. Histol. Histopathol. 2002, 17:845-850.
    • (2002) Histol. Histopathol. , vol.17 , pp. 845-850
    • Yoshizaki, T.1
  • 6
    • 0017695014 scopus 로고
    • Nasopharyngeal cancer in Greenland, The incidence in an Arctic Eskimo population
    • Nielsen N.H., Mikkelsen F., Hansen J.P. Nasopharyngeal cancer in Greenland, The incidence in an Arctic Eskimo population. Acta Pathol. Microbiol. Scand. A 1977, 85:850-858.
    • (1977) Acta Pathol. Microbiol. Scand. A , vol.85 , pp. 850-858
    • Nielsen, N.H.1    Mikkelsen, F.2    Hansen, J.P.3
  • 7
    • 0016189478 scopus 로고
    • The effect of migration on the risk of nasopharyngeal cancer among Chinese
    • Buell P. The effect of migration on the risk of nasopharyngeal cancer among Chinese. Cancer Res. 1974, 34:1189-1191.
    • (1974) Cancer Res. , vol.34 , pp. 1189-1191
    • Buell, P.1
  • 8
    • 0021994192 scopus 로고
    • Nasopharyngeal carcinoma: an evaluation of 134 patients treated between 1971-1980
    • Dickson R.I., Flores A.D. Nasopharyngeal carcinoma: an evaluation of 134 patients treated between 1971-1980. Laryngoscope 1985, 95:276-283.
    • (1985) Laryngoscope , vol.95 , pp. 276-283
    • Dickson, R.I.1    Flores, A.D.2
  • 9
    • 0018241546 scopus 로고
    • Histological typing of nasopharyngeal carcinoma
    • Shanmugaratnam K. Histological typing of nasopharyngeal carcinoma. IARC Sci. Publ. 1978, 3-12.
    • (1978) IARC Sci. Publ. , pp. 3-12
    • Shanmugaratnam, K.1
  • 10
    • 0018183888 scopus 로고
    • Proposal for a new histopathological classification of the carcinomas of the nasopharynx
    • Micheau C., Rilke F., Pilotti S. Proposal for a new histopathological classification of the carcinomas of the nasopharynx. Tumori 1978, 64:513-518.
    • (1978) Tumori , vol.64 , pp. 513-518
    • Micheau, C.1    Rilke, F.2    Pilotti, S.3
  • 14
    • 0002358470 scopus 로고    scopus 로고
    • Nasopharyngeal carcinoma: classification and histological appearances
    • JM N. Nasopharyngeal carcinoma: classification and histological appearances. Adv. Anat. Pathol. 1997, 4:71-84.
    • (1997) Adv. Anat. Pathol. , vol.4 , pp. 71-84
    • JM, N.1
  • 16
    • 0032147260 scopus 로고    scopus 로고
    • The National Cancer Data Base report on the relationship of race and national origin to the histology of nasopharyngeal carcinoma
    • Marks J.E., Phillips J.L., Menck H.R. The National Cancer Data Base report on the relationship of race and national origin to the histology of nasopharyngeal carcinoma. Cancer 1998, 83:582-588.
    • (1998) Cancer , vol.83 , pp. 582-588
    • Marks, J.E.1    Phillips, J.L.2    Menck, H.R.3
  • 17
    • 0022309824 scopus 로고
    • An EBV membrane protein expressed in immortalized lymphocytes transforms established rodent cells
    • Wang D., Liebowitz D., Kieff E. An EBV membrane protein expressed in immortalized lymphocytes transforms established rodent cells. Cell 1985, 43:831-840.
    • (1985) Cell , vol.43 , pp. 831-840
    • Wang, D.1    Liebowitz, D.2    Kieff, E.3
  • 19
    • 0029736941 scopus 로고    scopus 로고
    • Induction of apoptosis in epithelial cells by Epstein-Barr virus latent membrane protein 1
    • Lu J.J., Chen J.Y., Hsu T.Y., Yu W.C., Su I.J., Yang C.S. Induction of apoptosis in epithelial cells by Epstein-Barr virus latent membrane protein 1. J. Gen. Virol. 1996, 77(Pt 8):1883-1892.
    • (1996) J. Gen. Virol. , vol.77 , Issue.PART 8 , pp. 1883-1892
    • Lu, J.J.1    Chen, J.Y.2    Hsu, T.Y.3    Yu, W.C.4    Su, I.J.5    Yang, C.S.6
  • 20
    • 0036186372 scopus 로고    scopus 로고
    • Latent membrane protein-1 of Epstein-Barr virus inhibits cell growth and induces sensitivity to cisplatin in nasopharyngeal carcinoma cells
    • Liu Y., Wang X., Lo A.K., Wong Y.C., Cheung A.L., Tsao S.W. Latent membrane protein-1 of Epstein-Barr virus inhibits cell growth and induces sensitivity to cisplatin in nasopharyngeal carcinoma cells. J. Med. Virol. 2002, 66:63-69.
    • (2002) J. Med. Virol. , vol.66 , pp. 63-69
    • Liu, Y.1    Wang, X.2    Lo, A.K.3    Wong, Y.C.4    Cheung, A.L.5    Tsao, S.W.6
  • 21
    • 0036934692 scopus 로고    scopus 로고
    • Apoptosis modulation of Epstein-Barr virus-encoded latent membrane protein 1 in the epithelial cell line HeLa is stimulus-dependent
    • Zhang X., Hu L., Fadeel B., Ernberg I.T. Apoptosis modulation of Epstein-Barr virus-encoded latent membrane protein 1 in the epithelial cell line HeLa is stimulus-dependent. Virology 2002, 304:330-341.
    • (2002) Virology , vol.304 , pp. 330-341
    • Zhang, X.1    Hu, L.2    Fadeel, B.3    Ernberg, I.T.4
  • 22
    • 1942535076 scopus 로고    scopus 로고
    • Epstein-Barr virus latent membrane protein 1 induces micronucleus formation, represses DNA repair and enhances sensitivity to DNA-damaging agents in human epithelial cells
    • Liu M.T., Chen Y.R., Chen S.C., Hu C.Y., Lin C.S., Chang Y.T., Wang W.B., Chen J.Y. Epstein-Barr virus latent membrane protein 1 induces micronucleus formation, represses DNA repair and enhances sensitivity to DNA-damaging agents in human epithelial cells. Oncogene 2004, 23:2531-2539.
    • (2004) Oncogene , vol.23 , pp. 2531-2539
    • Liu, M.T.1    Chen, Y.R.2    Chen, S.C.3    Hu, C.Y.4    Lin, C.S.5    Chang, Y.T.6    Wang, W.B.7    Chen, J.Y.8
  • 26
    • 0032584221 scopus 로고    scopus 로고
    • The expression of matrix metalloproteinase 9 is enhanced by Epstein-Barr virus latent membrane protein 1
    • Yoshizaki T., Sato H., Furukawa M., Pagano J.S. The expression of matrix metalloproteinase 9 is enhanced by Epstein-Barr virus latent membrane protein 1. Proc. Natl. Acad. Sci. USA 1998, 95:3621-3626.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 3621-3626
    • Yoshizaki, T.1    Sato, H.2    Furukawa, M.3    Pagano, J.S.4
  • 27
    • 0034663173 scopus 로고    scopus 로고
    • Association of latent membrane protein 1 and matrix metalloproteinase 9 with metastasis in nasopharyngeal carcinoma
    • Horikawa T., Yoshizaki T., Sheen T.S., Lee S.Y., Furukawa M. Association of latent membrane protein 1 and matrix metalloproteinase 9 with metastasis in nasopharyngeal carcinoma. Cancer 2000, 89:715-723.
    • (2000) Cancer , vol.89 , pp. 715-723
    • Horikawa, T.1    Yoshizaki, T.2    Sheen, T.S.3    Lee, S.Y.4    Furukawa, M.5
  • 28
    • 35348913957 scopus 로고    scopus 로고
    • Induction of matrix metalloproteinases by Epstein-Barr virus latent membrane protein 1 isolated from nasopharyngeal carcinoma
    • Lee D.C., Chua D.T., Wei W.I., Sham J.S., Lau A.S. Induction of matrix metalloproteinases by Epstein-Barr virus latent membrane protein 1 isolated from nasopharyngeal carcinoma. Biomed. Pharmacother. 2007, 61:520-526.
    • (2007) Biomed. Pharmacother. , vol.61 , pp. 520-526
    • Lee, D.C.1    Chua, D.T.2    Wei, W.I.3    Sham, J.S.4    Lau, A.S.5
  • 29
    • 84355161630 scopus 로고    scopus 로고
    • LMP1 expression is positively associated with metastasis of nasopharyngeal carcinoma: evidence from a meta-analysis
    • Zhao Y., Wang Y., Zeng S., Hu X. LMP1 expression is positively associated with metastasis of nasopharyngeal carcinoma: evidence from a meta-analysis. J. Clin. Pathol. 2012, 65:41-45.
    • (2012) J. Clin. Pathol. , vol.65 , pp. 41-45
    • Zhao, Y.1    Wang, Y.2    Zeng, S.3    Hu, X.4
  • 30
    • 22144492282 scopus 로고    scopus 로고
    • EBV latent membrane protein 1 abundance correlates with patient age but not with metastatic behavior in north African nasopharyngeal carcinomas
    • Khabir A., Karray H., Rodriguez S., Rose M., Daoud J., Frikha M., Boudawara T., Middeldorp J., Jlidi R., Busson P. EBV latent membrane protein 1 abundance correlates with patient age but not with metastatic behavior in north African nasopharyngeal carcinomas. Virol. J. 2005, 2:39.
    • (2005) Virol. J. , vol.2 , pp. 39
    • Khabir, A.1    Karray, H.2    Rodriguez, S.3    Rose, M.4    Daoud, J.5    Frikha, M.6    Boudawara, T.7    Middeldorp, J.8    Jlidi, R.9    Busson, P.10
  • 31
    • 0034732153 scopus 로고    scopus 로고
    • Transformation of Madin-Darby canine kidney (MDCK) epithelial cells by Epstein-Barr virus latent membrane protein 1 (LMP1) induces expression of Ets1 and invasive growth
    • Kim K.R., Yoshizaki T., Miyamori H., Hasegawa K., Horikawa T., Furukawa M., Harada S., Seiki M., Sato H. Transformation of Madin-Darby canine kidney (MDCK) epithelial cells by Epstein-Barr virus latent membrane protein 1 (LMP1) induces expression of Ets1 and invasive growth. Oncogene 2000, 19:1764-1771.
    • (2000) Oncogene , vol.19 , pp. 1764-1771
    • Kim, K.R.1    Yoshizaki, T.2    Miyamori, H.3    Hasegawa, K.4    Horikawa, T.5    Furukawa, M.6    Harada, S.7    Seiki, M.8    Sato, H.9
  • 32
    • 0035403317 scopus 로고    scopus 로고
    • Induction of c-Met proto-oncogene by Epstein-Barr virus latent membrane protein-1 and the correlation with cervical lymph node metastasis of nasopharyngeal carcinoma
    • Horikawa T., Sheen T.S., Takeshita H., Sato H., Furukawa M., Yoshizaki T. Induction of c-Met proto-oncogene by Epstein-Barr virus latent membrane protein-1 and the correlation with cervical lymph node metastasis of nasopharyngeal carcinoma. Am. J. Pathol. 2001, 159:27-33.
    • (2001) Am. J. Pathol. , vol.159 , pp. 27-33
    • Horikawa, T.1    Sheen, T.S.2    Takeshita, H.3    Sato, H.4    Furukawa, M.5    Yoshizaki, T.6
  • 33
    • 64949141535 scopus 로고    scopus 로고
    • Phosphorylated ezrin is associated with EBV latent membrane protein 1 in nasopharyngeal carcinoma and induces cell migration
    • Endo K., Kondo S., Shackleford J., Horikawa T., Kitagawa N., Yoshizaki T., Furukawa M., Zen Y., Pagano J.S. Phosphorylated ezrin is associated with EBV latent membrane protein 1 in nasopharyngeal carcinoma and induces cell migration. Oncogene 2009, 28:1725-1735.
    • (2009) Oncogene , vol.28 , pp. 1725-1735
    • Endo, K.1    Kondo, S.2    Shackleford, J.3    Horikawa, T.4    Kitagawa, N.5    Yoshizaki, T.6    Furukawa, M.7    Zen, Y.8    Pagano, J.S.9
  • 34
    • 67651006731 scopus 로고    scopus 로고
    • Epstein-Barr virus latent membrane protein-1 effects on junctional plakoglobin and induction of a cadherin switch
    • Shair K.H., Schnegg C.I., Raab-Traub N. Epstein-Barr virus latent membrane protein-1 effects on junctional plakoglobin and induction of a cadherin switch. Cancer Res. 2009, 69:5734-5742.
    • (2009) Cancer Res. , vol.69 , pp. 5734-5742
    • Shair, K.H.1    Schnegg, C.I.2    Raab-Traub, N.3
  • 35
    • 33846841171 scopus 로고    scopus 로고
    • MUC1 induced by Epstein-Barr virus latent membrane protein 1 causes dissociation of the cell-matrix interaction and cellular invasiveness via STAT signaling
    • Kondo S., Yoshizaki T., Wakisaka N., Horikawa T., Murono S., Jang K.L., Joab I., Furukawa M., Pagano J.S. MUC1 induced by Epstein-Barr virus latent membrane protein 1 causes dissociation of the cell-matrix interaction and cellular invasiveness via STAT signaling. J. Virol. 2007, 81:1554-1562.
    • (2007) J. Virol. , vol.81 , pp. 1554-1562
    • Kondo, S.1    Yoshizaki, T.2    Wakisaka, N.3    Horikawa, T.4    Murono, S.5    Jang, K.L.6    Joab, I.7    Furukawa, M.8    Pagano, J.S.9
  • 36
    • 0034192392 scopus 로고    scopus 로고
    • Aspirin inhibits tumor cell invasiveness induced by Epstein-Barr virus latent membrane protein 1 through suppression of matrix metalloproteinase-9 expression
    • Murono S., Yoshizaki T., Sato H., Takeshita H., Furukawa M., Pagano J.S. Aspirin inhibits tumor cell invasiveness induced by Epstein-Barr virus latent membrane protein 1 through suppression of matrix metalloproteinase-9 expression. Cancer Res. 2000, 60:2555-2561.
    • (2000) Cancer Res. , vol.60 , pp. 2555-2561
    • Murono, S.1    Yoshizaki, T.2    Sato, H.3    Takeshita, H.4    Furukawa, M.5    Pagano, J.S.6
  • 37
    • 0344010693 scopus 로고    scopus 로고
    • RECK is a target of Epstein-Barr virus latent membrane protein 1
    • Liu L.T., Peng J.P., Chang H.C., Hung W.C. RECK is a target of Epstein-Barr virus latent membrane protein 1. Oncogene 2003, 22:8263-8270.
    • (2003) Oncogene , vol.22 , pp. 8263-8270
    • Liu, L.T.1    Peng, J.P.2    Chang, H.C.3    Hung, W.C.4
  • 38
    • 18644368754 scopus 로고    scopus 로고
    • Epstein-Barr virus latent membrane protein 1 induces the matrix metalloproteinase-1 promoter via an Ets binding site formed by a single nucleotide polymorphism: enhanced susceptibility to nasopharyngeal carcinoma
    • Kondo S., Wakisaka N., Schell M.J., Horikawa T., Sheen T.S., Sato H., Furukawa M., Pagano J.S., Yoshizaki T. Epstein-Barr virus latent membrane protein 1 induces the matrix metalloproteinase-1 promoter via an Ets binding site formed by a single nucleotide polymorphism: enhanced susceptibility to nasopharyngeal carcinoma. Int. J. Cancer 2005, 115:368-376.
    • (2005) Int. J. Cancer , vol.115 , pp. 368-376
    • Kondo, S.1    Wakisaka, N.2    Schell, M.J.3    Horikawa, T.4    Sheen, T.S.5    Sato, H.6    Furukawa, M.7    Pagano, J.S.8    Yoshizaki, T.9
  • 39
    • 77958030259 scopus 로고    scopus 로고
    • Interleukins, laminin and Epstein - Barr virus latent membrane protein 1 (EBV LMP1) promote metastatic phenotype in nasopharyngeal carcinoma
    • Chew M.M., Gan S.Y., Khoo A.S., Tan E.L. Interleukins, laminin and Epstein - Barr virus latent membrane protein 1 (EBV LMP1) promote metastatic phenotype in nasopharyngeal carcinoma. BMC Cancer 2010, 10:574.
    • (2010) BMC Cancer , vol.10 , pp. 574
    • Chew, M.M.1    Gan, S.Y.2    Khoo, A.S.3    Tan, E.L.4
  • 40
    • 0029775242 scopus 로고    scopus 로고
    • Association between tumor hypoxia and malignant progression in advanced cancer of the uterine cervix
    • Hockel M., Schlenger K., Aral B., Mitze M., Schaffer U., Vaupel P. Association between tumor hypoxia and malignant progression in advanced cancer of the uterine cervix. Cancer Res. 1996, 56:4509-4515.
    • (1996) Cancer Res. , vol.56 , pp. 4509-4515
    • Hockel, M.1    Schlenger, K.2    Aral, B.3    Mitze, M.4    Schaffer, U.5    Vaupel, P.6
  • 41
    • 0036023422 scopus 로고    scopus 로고
    • Coexpression of hypoxia-inducible factors 1alpha and 2alpha, carbonic anhydrase IX, and vascular endothelial growth factor in nasopharyngeal carcinoma and relationship to survival
    • Hui E.P., Chan A.T., Pezzella F., Turley H., To K.F., Poon T.C., Zee B., Mo F., Teo P.M., Huang D.P., Gatter K.C., Johnson P.J., Harris A.L. Coexpression of hypoxia-inducible factors 1alpha and 2alpha, carbonic anhydrase IX, and vascular endothelial growth factor in nasopharyngeal carcinoma and relationship to survival. Clin. Cancer Res. 2002, 8:2595-2604.
    • (2002) Clin. Cancer Res. , vol.8 , pp. 2595-2604
    • Hui, E.P.1    Chan, A.T.2    Pezzella, F.3    Turley, H.4    To, K.F.5    Poon, T.C.6    Zee, B.7    Mo, F.8    Teo, P.M.9    Huang, D.P.10    Gatter, K.C.11    Johnson, P.J.12    Harris, A.L.13
  • 42
    • 33750537081 scopus 로고    scopus 로고
    • EBV latent membrane protein 1 up-regulates hypoxia-inducible factor 1alpha through Siah1-mediated down-regulation of prolyl hydroxylases 1 and 3 in nasopharyngeal epithelial cells
    • Kondo S., Seo S.Y., Yoshizaki T., Wakisaka N., Furukawa M., Joab I., Jang K.L., Pagano J.S. EBV latent membrane protein 1 up-regulates hypoxia-inducible factor 1alpha through Siah1-mediated down-regulation of prolyl hydroxylases 1 and 3 in nasopharyngeal epithelial cells. Cancer Res. 2006, 66:9870-9877.
    • (2006) Cancer Res. , vol.66 , pp. 9870-9877
    • Kondo, S.1    Seo, S.Y.2    Yoshizaki, T.3    Wakisaka, N.4    Furukawa, M.5    Joab, I.6    Jang, K.L.7    Pagano, J.S.8
  • 44
    • 84873524916 scopus 로고    scopus 로고
    • Expression of seven-in-absentia homologue 1 and hypoxia-inducible factor 1 alpha: novel prognostic factors of nasopharyngeal carcinoma
    • Kitagawa N., Kondo S., Wakisaka N., Zen Y., Nakanishi Y., Tsuji A., Endo K., Murono S., Yoshizaki T. Expression of seven-in-absentia homologue 1 and hypoxia-inducible factor 1 alpha: novel prognostic factors of nasopharyngeal carcinoma. Cancer Lett. 2013, 331:52-57.
    • (2013) Cancer Lett. , vol.331 , pp. 52-57
    • Kitagawa, N.1    Kondo, S.2    Wakisaka, N.3    Zen, Y.4    Nakanishi, Y.5    Tsuji, A.6    Endo, K.7    Murono, S.8    Yoshizaki, T.9
  • 46
    • 0035811070 scopus 로고    scopus 로고
    • Induction of cyclooxygenase-2 by Epstein-Barr virus latent membrane protein 1 is involved in vascular endothelial growth factor production in nasopharyngeal carcinoma cells
    • Murono S., Inoue H., Tanabe T., Joab I., Yoshizaki T., Furukawa M., Pagano J.S. Induction of cyclooxygenase-2 by Epstein-Barr virus latent membrane protein 1 is involved in vascular endothelial growth factor production in nasopharyngeal carcinoma cells. Proc. Natl. Acad. Sci. USA 2001, 98:6905-6910.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 6905-6910
    • Murono, S.1    Inoue, H.2    Tanabe, T.3    Joab, I.4    Yoshizaki, T.5    Furukawa, M.6    Pagano, J.S.7
  • 47
    • 0036829132 scopus 로고    scopus 로고
    • Epstein-barr virus latent membrane protein 1 induces and causes release of fibroblast growth factor-2
    • Wakisaka N., Murono S., Yoshizaki T., Furukawa M., Pagano J.S. Epstein-barr virus latent membrane protein 1 induces and causes release of fibroblast growth factor-2. Cancer Res. 2002, 62:6337-6344.
    • (2002) Cancer Res. , vol.62 , pp. 6337-6344
    • Wakisaka, N.1    Murono, S.2    Yoshizaki, T.3    Furukawa, M.4    Pagano, J.S.5
  • 48
    • 2542443138 scopus 로고    scopus 로고
    • Epstein-Barr virus latent membrane protein 1 induces synthesis of hypoxia-inducible factor 1 alpha
    • Wakisaka N., Kondo S., Yoshizaki T., Murono S., Furukawa M., Pagano J.S. Epstein-Barr virus latent membrane protein 1 induces synthesis of hypoxia-inducible factor 1 alpha. Mol. Cell. Biol. 2004, 24:5223-5234.
    • (2004) Mol. Cell. Biol. , vol.24 , pp. 5223-5234
    • Wakisaka, N.1    Kondo, S.2    Yoshizaki, T.3    Murono, S.4    Furukawa, M.5    Pagano, J.S.6
  • 49
    • 0034781792 scopus 로고    scopus 로고
    • Induction of interleukin-8 by Epstein-Barr virus latent membrane protein-1 and its correlation to angiogenesis in nasopharyngeal carcinoma
    • Yoshizaki T., Horikawa T., Qing-Chun R., Wakisaka N., Takeshita H., Sheen T.S., Lee S.Y., Sato H., Furukawa M. Induction of interleukin-8 by Epstein-Barr virus latent membrane protein-1 and its correlation to angiogenesis in nasopharyngeal carcinoma. Clin. Cancer Res. 2001, 7:1946-1951.
    • (2001) Clin. Cancer Res. , vol.7 , pp. 1946-1951
    • Yoshizaki, T.1    Horikawa, T.2    Qing-Chun, R.3    Wakisaka, N.4    Takeshita, H.5    Sheen, T.S.6    Lee, S.Y.7    Sato, H.8    Furukawa, M.9
  • 50
    • 2442511257 scopus 로고    scopus 로고
    • Epstein-Barr virus (EBV) latent membrane protein 1 induces interleukin-8 through the nuclear factor-kappa B signaling pathway in EBV-infected nasopharyngeal carcinoma cell line
    • Ren Q., Sato H., Murono S., Furukawa M., Yoshizaki T. Epstein-Barr virus (EBV) latent membrane protein 1 induces interleukin-8 through the nuclear factor-kappa B signaling pathway in EBV-infected nasopharyngeal carcinoma cell line. Laryngoscope 2004, 114:855-859.
    • (2004) Laryngoscope , vol.114 , pp. 855-859
    • Ren, Q.1    Sato, H.2    Murono, S.3    Furukawa, M.4    Yoshizaki, T.5
  • 51
    • 0033523115 scopus 로고    scopus 로고
    • Activation of the p38 mitogen-activated protein kinase pathway by Epstein-Barr virus-encoded latent membrane protein 1 coregulates interleukin-6 and interleukin-8 production
    • Eliopoulos A.G., Gallagher N.J., Blake S.M., Dawson C.W., Young L.S. Activation of the p38 mitogen-activated protein kinase pathway by Epstein-Barr virus-encoded latent membrane protein 1 coregulates interleukin-6 and interleukin-8 production. J. Biol. Chem. 1999, 274:16085-16096.
    • (1999) J. Biol. Chem. , vol.274 , pp. 16085-16096
    • Eliopoulos, A.G.1    Gallagher, N.J.2    Blake, S.M.3    Dawson, C.W.4    Young, L.S.5
  • 52
    • 11844253222 scopus 로고    scopus 로고
    • Expression of interleukin-8 receptor A predicts poor outcome in patients with nasopharyngeal carcinoma
    • Horikawa T., Kaizaki Y., Kato H., Furukawa M., Yoshizaki T. Expression of interleukin-8 receptor A predicts poor outcome in patients with nasopharyngeal carcinoma. Laryngoscope 2005, 115:62-67.
    • (2005) Laryngoscope , vol.115 , pp. 62-67
    • Horikawa, T.1    Kaizaki, Y.2    Kato, H.3    Furukawa, M.4    Yoshizaki, T.5
  • 53
    • 53049087445 scopus 로고    scopus 로고
    • Induction of receptor for advanced glycation end products by EBV latent membrane protein 1 and its correlation with angiogenesis and cervical lymph node metastasis in nasopharyngeal carcinoma
    • Tsuji A., Wakisaka N., Kondo S., Murono S., Furukawa M., Yoshizaki T. Induction of receptor for advanced glycation end products by EBV latent membrane protein 1 and its correlation with angiogenesis and cervical lymph node metastasis in nasopharyngeal carcinoma. Clin. Cancer Res. 2008, 14:5368-5375.
    • (2008) Clin. Cancer Res. , vol.14 , pp. 5368-5375
    • Tsuji, A.1    Wakisaka, N.2    Kondo, S.3    Murono, S.4    Furukawa, M.5    Yoshizaki, T.6
  • 54
    • 84864399955 scopus 로고    scopus 로고
    • Induction of lymphangiogenesis through vascular endothelial growth factor-C/vascular endothelial growth factor receptor 3 axis and its correlation with lymph node metastasis in nasopharyngeal carcinoma
    • Wakisaka N., Hirota K., Kondo S., Sawada-Kitamura S., Endo K., Murono S., Yoshizaki T. Induction of lymphangiogenesis through vascular endothelial growth factor-C/vascular endothelial growth factor receptor 3 axis and its correlation with lymph node metastasis in nasopharyngeal carcinoma. Oral Oncol. 2012, 48:703-708.
    • (2012) Oral Oncol. , vol.48 , pp. 703-708
    • Wakisaka, N.1    Hirota, K.2    Kondo, S.3    Sawada-Kitamura, S.4    Endo, K.5    Murono, S.6    Yoshizaki, T.7
  • 55
    • 0036595629 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transitions in tumour progression
    • Thiery J.P. Epithelial-mesenchymal transitions in tumour progression. Nat. Rev. Cancer 2002, 2:442-454.
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 442-454
    • Thiery, J.P.1
  • 56
    • 21244437500 scopus 로고    scopus 로고
    • Expression of the transcription factors snail, slug, and twist and their clinical significance in human breast cancer
    • Martin T.A., Goyal A., Watkins G., Jiang W.G. Expression of the transcription factors snail, slug, and twist and their clinical significance in human breast cancer. Ann. Surg. Oncol. 2005, 12:488-496.
    • (2005) Ann. Surg. Oncol. , vol.12 , pp. 488-496
    • Martin, T.A.1    Goyal, A.2    Watkins, G.3    Jiang, W.G.4
  • 57
    • 0032940579 scopus 로고    scopus 로고
    • Downregulation and abnormal expression of E-cadherin and beta-catenin in nasopharyngeal carcinoma: close association with advanced disease stage and lymph node metastasis
    • Zheng Z., Pan J., Chu B., Wong Y.C., Cheung A.L., Tsao S.W. Downregulation and abnormal expression of E-cadherin and beta-catenin in nasopharyngeal carcinoma: close association with advanced disease stage and lymph node metastasis. Hum. Pathol. 1999, 30:458-466.
    • (1999) Hum. Pathol. , vol.30 , pp. 458-466
    • Zheng, Z.1    Pan, J.2    Chu, B.3    Wong, Y.C.4    Cheung, A.L.5    Tsao, S.W.6
  • 58
    • 0037162536 scopus 로고    scopus 로고
    • The Epstein-Barr virus oncogene product, latent membrane protein 1, induces the downregulation of E-cadherin gene expression via activation of DNA methyltransferases
    • Tsai C.N., Tsai C.L., Tse K.P., Chang H.Y., Chang Y.S. The Epstein-Barr virus oncogene product, latent membrane protein 1, induces the downregulation of E-cadherin gene expression via activation of DNA methyltransferases. Proc. Natl. Acad. Sci. USA 2002, 99:10084-10089.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 10084-10089
    • Tsai, C.N.1    Tsai, C.L.2    Tse, K.P.3    Chang, H.Y.4    Chang, Y.S.5
  • 59
    • 33947196379 scopus 로고    scopus 로고
    • Twist and epithelial-mesenchymal transition are induced by the EBV oncoprotein latent membrane protein 1 and are associated with metastatic nasopharyngeal carcinoma
    • Horikawa T., Yang J., Kondo S., Yoshizaki T., Joab I., Furukawa M., Pagano J.S. Twist and epithelial-mesenchymal transition are induced by the EBV oncoprotein latent membrane protein 1 and are associated with metastatic nasopharyngeal carcinoma. Cancer Res. 2007, 67:1970-1978.
    • (2007) Cancer Res. , vol.67 , pp. 1970-1978
    • Horikawa, T.1    Yang, J.2    Kondo, S.3    Yoshizaki, T.4    Joab, I.5    Furukawa, M.6    Pagano, J.S.7
  • 60
    • 79953166389 scopus 로고    scopus 로고
    • Epstein-Barr Virus latent membrane protein 1 induces Snail and epithelial-mesenchymal transition in metastatic nasopharyngeal carcinoma
    • Horikawa T., Yoshizaki T., Kondo S., Furukawa M., Kaizaki Y., Pagano J.S. Epstein-Barr Virus latent membrane protein 1 induces Snail and epithelial-mesenchymal transition in metastatic nasopharyngeal carcinoma. Br. J. Cancer 2011, 104:1160-1167.
    • (2011) Br. J. Cancer , vol.104 , pp. 1160-1167
    • Horikawa, T.1    Yoshizaki, T.2    Kondo, S.3    Furukawa, M.4    Kaizaki, Y.5    Pagano, J.S.6
  • 62
    • 40749094918 scopus 로고    scopus 로고
    • SATB1 reprogrammes gene expression to promote breast tumour growth and metastasis
    • Han H.J., Russo J., Kohwi Y., Kohwi-Shigematsu T. SATB1 reprogrammes gene expression to promote breast tumour growth and metastasis. Nature 2008, 452:187-193.
    • (2008) Nature , vol.452 , pp. 187-193
    • Han, H.J.1    Russo, J.2    Kohwi, Y.3    Kohwi-Shigematsu, T.4
  • 63
    • 84874089640 scopus 로고    scopus 로고
    • Up-regulation of SATB1 by EBV LMP1 in human nasopharyngeal cells and nasopharyngeal cancer
    • Endo K., Shackelford J., Aga M., Yoshizaki T., Pagano J.S. Up-regulation of SATB1 by EBV LMP1 in human nasopharyngeal cells and nasopharyngeal cancer. J Gen Virol. 2013, 94:507-513.
    • (2013) J Gen Virol. , vol.94 , pp. 507-513
    • Endo, K.1    Shackelford, J.2    Aga, M.3    Yoshizaki, T.4    Pagano, J.S.5
  • 66
    • 43149120419 scopus 로고    scopus 로고
    • Exosome function: from tumor immunology to pathogen biology
    • Schorey J.S., Bhatnagar S. Exosome function: from tumor immunology to pathogen biology. Traffic 2008, 9:871-881.
    • (2008) Traffic , vol.9 , pp. 871-881
    • Schorey, J.S.1    Bhatnagar, S.2
  • 67
    • 67949097489 scopus 로고    scopus 로고
    • Exosomes-vesicular carriers for intercellular communication
    • Simons M., Raposo G. Exosomes-vesicular carriers for intercellular communication. Curr. Opin. Cell Biol. 2009, 21:575-581.
    • (2009) Curr. Opin. Cell Biol. , vol.21 , pp. 575-581
    • Simons, M.1    Raposo, G.2
  • 68
    • 34548814463 scopus 로고    scopus 로고
    • A new diagnostic marker for secreted Epstein-Barr virus encoded LMP1 and BARF1 oncoproteins in the serum and saliva of patients with nasopharyngeal carcinoma
    • Houali K., Wang X., Shimizu Y., Djennaoui D., Nicholls J., Fiorini S., Bouguermouh A., Ooka T. A new diagnostic marker for secreted Epstein-Barr virus encoded LMP1 and BARF1 oncoproteins in the serum and saliva of patients with nasopharyngeal carcinoma. Clin. Cancer Res. 2007, 13:4993-5000.
    • (2007) Clin. Cancer Res. , vol.13 , pp. 4993-5000
    • Houali, K.1    Wang, X.2    Shimizu, Y.3    Djennaoui, D.4    Nicholls, J.5    Fiorini, S.6    Bouguermouh, A.7    Ooka, T.8
  • 70
    • 0037813157 scopus 로고    scopus 로고
    • Localization of the Epstein-Barr virus protein LMP 1 to exosomes
    • Flanagan J., Middeldorp J., Sculley T. Localization of the Epstein-Barr virus protein LMP 1 to exosomes. J. Gen. Virol. 2003, 84:1871-1879.
    • (2003) J. Gen. Virol. , vol.84 , pp. 1871-1879
    • Flanagan, J.1    Middeldorp, J.2    Sculley, T.3
  • 71
    • 34948874323 scopus 로고    scopus 로고
    • T cell-induced secretion of MHC class II-peptide complexes on B cell exosomes
    • Muntasell A., Berger A.C., Roche P.A. T cell-induced secretion of MHC class II-peptide complexes on B cell exosomes. EMBO J. 2007, 26:4263-4272.
    • (2007) EMBO J. , vol.26 , pp. 4263-4272
    • Muntasell, A.1    Berger, A.C.2    Roche, P.A.3
  • 72
    • 56949099838 scopus 로고    scopus 로고
    • Multiple roles of LMP1 in Epstein-Barr virus induced immune escape
    • Middeldorp J.M., Pegtel D.M. Multiple roles of LMP1 in Epstein-Barr virus induced immune escape. Semin. Cancer Biol. 2008, 18:388-396.
    • (2008) Semin. Cancer Biol. , vol.18 , pp. 388-396
    • Middeldorp, J.M.1    Pegtel, D.M.2
  • 74
    • 0035139943 scopus 로고    scopus 로고
    • Hostile takeovers: viral appropriation of the NF-kappaB pathway
    • Hiscott J., Kwon H., Genin P. Hostile takeovers: viral appropriation of the NF-kappaB pathway. J. Clin. Invest. 2001, 107:143-151.
    • (2001) J. Clin. Invest. , vol.107 , pp. 143-151
    • Hiscott, J.1    Kwon, H.2    Genin, P.3
  • 76
    • 0033567145 scopus 로고    scopus 로고
    • Signature amino acid changes in latent membrane protein 1 distinguish Epstein-Barr virus strains
    • Edwards R.H., Seillier-Moiseiwitsch F., Raab-Traub N. Signature amino acid changes in latent membrane protein 1 distinguish Epstein-Barr virus strains. Virology 1999, 261:79-95.
    • (1999) Virology , vol.261 , pp. 79-95
    • Edwards, R.H.1    Seillier-Moiseiwitsch, F.2    Raab-Traub, N.3
  • 77
    • 0025953468 scopus 로고
    • Isolation and sequencing of the Epstein-Barr virus BNLF-1 gene (LMP1) from a Chinese nasopharyngeal carcinoma
    • Hu L.F., Zabarovsky E.R., Chen F., Cao S.L., Ernberg I., Klein G., Winberg G. Isolation and sequencing of the Epstein-Barr virus BNLF-1 gene (LMP1) from a Chinese nasopharyngeal carcinoma. J. Gen. Virol. 1991, 72(Pt 10):2399-2409.
    • (1991) J. Gen. Virol. , vol.72 , Issue.PART 10 , pp. 2399-2409
    • Hu, L.F.1    Zabarovsky, E.R.2    Chen, F.3    Cao, S.L.4    Ernberg, I.5    Klein, G.6    Winberg, G.7
  • 78
    • 0026459769 scopus 로고
    • Cloning and characterization of the latent membrane protein (LMP) of a specific Epstein-Barr virus variant derived from the nasopharyngeal carcinoma in the Taiwanese population
    • Chen M.L., Tsai C.N., Liang C.L., Shu C.H., Huang C.R., Sulitzeanu D., Liu S.T., Chang Y.S. Cloning and characterization of the latent membrane protein (LMP) of a specific Epstein-Barr virus variant derived from the nasopharyngeal carcinoma in the Taiwanese population. Oncogene 1992, 7:2131-2140.
    • (1992) Oncogene , vol.7 , pp. 2131-2140
    • Chen, M.L.1    Tsai, C.N.2    Liang, C.L.3    Shu, C.H.4    Huang, C.R.5    Sulitzeanu, D.6    Liu, S.T.7    Chang, Y.S.8
  • 79
    • 0027215533 scopus 로고
    • Clonability and tumorigenicity of human epithelial cells expressing the EBV encoded membrane protein LMP1
    • Hu L.F., Chen F., Zheng X., Ernberg I., Cao S.L., Christensson B., Klein G., Winberg G. Clonability and tumorigenicity of human epithelial cells expressing the EBV encoded membrane protein LMP1. Oncogene 1993, 8:1575-1583.
    • (1993) Oncogene , vol.8 , pp. 1575-1583
    • Hu, L.F.1    Chen, F.2    Zheng, X.3    Ernberg, I.4    Cao, S.L.5    Christensson, B.6    Klein, G.7    Winberg, G.8
  • 80
    • 0032499227 scopus 로고    scopus 로고
    • The NPC derived C15 LMP1 protein confers enhanced activation of NF-kappa B and induction of the EGFR in epithelial cells
    • Miller W.E., Cheshire J.L., Baldwin A.S., Raab-Traub N. The NPC derived C15 LMP1 protein confers enhanced activation of NF-kappa B and induction of the EGFR in epithelial cells. Oncogene 1998, 16:1869-1877.
    • (1998) Oncogene , vol.16 , pp. 1869-1877
    • Miller, W.E.1    Cheshire, J.L.2    Baldwin, A.S.3    Raab-Traub, N.4
  • 81
    • 0034691192 scopus 로고    scopus 로고
    • Identification of functional differences between prototype Epstein-Barr virus-encoded LMP1 and a nasopharyngeal carcinoma-derived LMP1 in human epithelial cells
    • Dawson C.W., Eliopoulos A.G., Blake S.M., Barker R., Young L.S. Identification of functional differences between prototype Epstein-Barr virus-encoded LMP1 and a nasopharyngeal carcinoma-derived LMP1 in human epithelial cells. Virology 2000, 272:204-217.
    • (2000) Virology , vol.272 , pp. 204-217
    • Dawson, C.W.1    Eliopoulos, A.G.2    Blake, S.M.3    Barker, R.4    Young, L.S.5
  • 82
    • 0035836377 scopus 로고    scopus 로고
    • The transmembrane domains of the EBV-encoded latent membrane protein 1 (LMP1) variant CAO regulate enhanced signalling activity
    • Blake S.M., Eliopoulos A.G., Dawson C.W., Young L.S. The transmembrane domains of the EBV-encoded latent membrane protein 1 (LMP1) variant CAO regulate enhanced signalling activity. Virology 2001, 282:278-287.
    • (2001) Virology , vol.282 , pp. 278-287
    • Blake, S.M.1    Eliopoulos, A.G.2    Dawson, C.W.3    Young, L.S.4
  • 83
    • 0034847766 scopus 로고    scopus 로고
    • Epstein-Barr virus LMP-1 natural sequence variants differ in their potential to activate cellular signaling pathways
    • Fielding C.A., Sandvej K., Mehl A., Brennan P., Jones M., Rowe M. Epstein-Barr virus LMP-1 natural sequence variants differ in their potential to activate cellular signaling pathways. J. Virol. 2001, 75:9129-9141.
    • (2001) J. Virol. , vol.75 , pp. 9129-9141
    • Fielding, C.A.1    Sandvej, K.2    Mehl, A.3    Brennan, P.4    Jones, M.5    Rowe, M.6
  • 85
    • 0029033861 scopus 로고
    • The retinoblastoma protein and cell cycle control
    • Weinberg R.A. The retinoblastoma protein and cell cycle control. Cell 1995, 81:323-330.
    • (1995) Cell , vol.81 , pp. 323-330
    • Weinberg, R.A.1
  • 86
    • 0031919421 scopus 로고    scopus 로고
    • Nasopharyngeal carcinomas frequently lack the p16/MTS1 tumor suppressor protein but consistently express the retinoblastoma gene product
    • Gulley M.L., Nicholls J.M., Schneider B.G., Amin M.B., Ro J.Y., Geradts J. Nasopharyngeal carcinomas frequently lack the p16/MTS1 tumor suppressor protein but consistently express the retinoblastoma gene product. Am. J. Pathol. 1998, 152:865-869.
    • (1998) Am. J. Pathol. , vol.152 , pp. 865-869
    • Gulley, M.L.1    Nicholls, J.M.2    Schneider, B.G.3    Amin, M.B.4    Ro, J.Y.5    Geradts, J.6
  • 88
    • 3142618391 scopus 로고    scopus 로고
    • Heterodimer formation between c-Jun and Jun B proteins mediated by Epstein-Barr virus encoded latent membrane protein 1
    • Song X., Tao Y.G., Deng X.Y., Jin X., Tan Y.N., Tang M., Wu Q., Lee L.M., Cao Y. Heterodimer formation between c-Jun and Jun B proteins mediated by Epstein-Barr virus encoded latent membrane protein 1. Cell. Signal. 2004, 16:1153-1162.
    • (2004) Cell. Signal. , vol.16 , pp. 1153-1162
    • Song, X.1    Tao, Y.G.2    Deng, X.Y.3    Jin, X.4    Tan, Y.N.5    Tang, M.6    Wu, Q.7    Lee, L.M.8    Cao, Y.9
  • 91
    • 0032816406 scopus 로고    scopus 로고
    • Detection of recurrent chromosomal gains and losses in primary nasopharyngeal carcinoma by comparative genomic hybridisation
    • Hui A.B., Lo K.W., Leung S.F., Teo P., Fung M.K., To K.F., Wong N., Choi P.H., Lee J.C., Huang D.P. Detection of recurrent chromosomal gains and losses in primary nasopharyngeal carcinoma by comparative genomic hybridisation. Int. J. Cancer 1999, 82:498-503.
    • (1999) Int. J. Cancer , vol.82 , pp. 498-503
    • Hui, A.B.1    Lo, K.W.2    Leung, S.F.3    Teo, P.4    Fung, M.K.5    To, K.F.6    Wong, N.7    Choi, P.H.8    Lee, J.C.9    Huang, D.P.10
  • 96
    • 0036433743 scopus 로고    scopus 로고
    • Genetic and epigenetic changes in nasopharyngeal carcinoma
    • Lo K.W., Huang D.P. Genetic and epigenetic changes in nasopharyngeal carcinoma. Semin. Cancer Biol. 2002, 12:451-462.
    • (2002) Semin. Cancer Biol. , vol.12 , pp. 451-462
    • Lo, K.W.1    Huang, D.P.2
  • 98
    • 33646168051 scopus 로고    scopus 로고
    • A combined computational and microarray-based approach identifies novel microRNAs encoded by human gamma-herpesviruses
    • Grundhoff A., Sullivan C.S., Ganem D. A combined computational and microarray-based approach identifies novel microRNAs encoded by human gamma-herpesviruses. RNA 2006, 12:733-750.
    • (2006) RNA , vol.12 , pp. 733-750
    • Grundhoff, A.1    Sullivan, C.S.2    Ganem, D.3
  • 104
    • 77957930209 scopus 로고    scopus 로고
    • MicroRNA-10b induced by Epstein-Barr virus-encoded latent membrane protein-1 promotes the metastasis of human nasopharyngeal carcinoma cells
    • Li G., Wu Z., Peng Y., Liu X., Lu J., Wang L., Pan Q., He M.L., Li X.P. MicroRNA-10b induced by Epstein-Barr virus-encoded latent membrane protein-1 promotes the metastasis of human nasopharyngeal carcinoma cells. Cancer Lett. 2010, 299:29-36.
    • (2010) Cancer Lett. , vol.299 , pp. 29-36
    • Li, G.1    Wu, Z.2    Peng, Y.3    Liu, X.4    Lu, J.5    Wang, L.6    Pan, Q.7    He, M.L.8    Li, X.P.9
  • 105
    • 79955622634 scopus 로고    scopus 로고
    • Upregulation of MiR-155 in nasopharyngeal carcinoma is partly driven by LMP1 and LMP2A and downregulates a negative prognostic marker JMJD1A
    • Du Z.M., Hu L.F., Wang H.Y., Yan L.X., Zeng Y.X., Shao J.Y., Ernberg I. Upregulation of MiR-155 in nasopharyngeal carcinoma is partly driven by LMP1 and LMP2A and downregulates a negative prognostic marker JMJD1A. PLoS ONE 2011, 6:e19137.
    • (2011) PLoS ONE , vol.6
    • Du, Z.M.1    Hu, L.F.2    Wang, H.Y.3    Yan, L.X.4    Zeng, Y.X.5    Shao, J.Y.6    Ernberg, I.7
  • 106
    • 72949119530 scopus 로고    scopus 로고
    • MiR-200a-mediated downregulation of ZEB2 and CTNNB1 differentially inhibits nasopharyngeal carcinoma cell growth, migration and invasion
    • Xia H., Ng S.S., Jiang S., Cheung W.K., Sze J., Bian X.W., Kung H.F., Lin M.C. MiR-200a-mediated downregulation of ZEB2 and CTNNB1 differentially inhibits nasopharyngeal carcinoma cell growth, migration and invasion. Biochem. Biophys. Res. Commun. 2010, 391:535-541.
    • (2010) Biochem. Biophys. Res. Commun. , vol.391 , pp. 535-541
    • Xia, H.1    Ng, S.S.2    Jiang, S.3    Cheung, W.K.4    Sze, J.5    Bian, X.W.6    Kung, H.F.7    Lin, M.C.8
  • 107
    • 0029051898 scopus 로고
    • Clonal proliferations of cells infected with Epstein-Barr virus in preinvasive lesions related to nasopharyngeal carcinoma
    • Pathmanathan R., Prasad U., Sadler R., Flynn K., Raab-Traub N. Clonal proliferations of cells infected with Epstein-Barr virus in preinvasive lesions related to nasopharyngeal carcinoma. N. Engl. J. Med. 1995, 333:693-698.
    • (1995) N. Engl. J. Med. , vol.333 , pp. 693-698
    • Pathmanathan, R.1    Prasad, U.2    Sadler, R.3    Flynn, K.4    Raab-Traub, N.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.