Application of a persistent heparin treatment inhibits the malignant potential of oral squamous carcinoma cells induced by tumor cell-derived exosomes

PLoS ONE

Volumn 11, Issue 2, 2016, Pages

  Sento, Shinya ^a   Sasabe, Eri ^a   Yamamoto, Tetsuya ^a  

^a KOCHI UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

HEPARIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; STRESS ACTIVATED PROTEIN KINASE 1; ANTINEOPLASTIC AGENT; MITOGEN ACTIVATED PROTEIN KINASE 9;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER CELL; CANCER GROWTH; CANCER INHIBITION; CELL INVASION; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; DOSAGE SCHEDULE COMPARISON; DRUG DOSE REGIMEN; DRUG EFFICACY; ENZYME ACTIVATION; EXOSOME; IN VITRO STUDY; IN VIVO STUDY; MOUSE; MOUTH SQUAMOUS CELL CARCINOMA; MULTIPLE DRUG DOSE; NONHUMAN; ORAL CANCER CELL LINE; SINGLE DRUG DOSE; TUMOR PROMOTION; TUMOR XENOGRAFT; ANIMAL; BAGG ALBINO MOUSE; CARCINOMA, SQUAMOUS CELL; CELL MOTION; DRUG EFFECTS; DRUG SCREENING; HUMAN; METABOLISM; MOUTH NEOPLASMS; PATHOLOGY; TUMOR CELL LINE;

ANIMALS; ANTINEOPLASTIC AGENTS; CARCINOMA, SQUAMOUS CELL; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; EXOSOMES; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HEPARIN; HUMANS; MICE, INBRED BALB C; MITOGEN-ACTIVATED PROTEIN KINASE 8; MITOGEN-ACTIVATED PROTEIN KINASE 9; MOUTH NEOPLASMS; PROTO-ONCOGENE PROTEINS C-AKT; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84959095969     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0148454     Document Type: Article

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