A Knowledge-Based System for Display and Prediction of O-Glycosylation Network Behaviour in Response to Enzyme Knockouts

PLoS Computational Biology

Volumn 12, Issue 4, 2016, Pages

  McDonald, Andrew G ^a   Tipton, Keith F ^a   Davey, Gavin P ^a  

^a TRINITY COLLEGE DUBLIN   (Ireland)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOSYLATION; GRAPH THEORY; KNOWLEDGE BASED SYSTEMS; PATTERN MATCHING; POISSON DISTRIBUTION; POLYSACCHARIDES;

GLYCOFORMS; GLYCOSYLATIONS; GRAPHICAL INTERPRETATIONS; KNOWLEDGE-BASED SYSTEMS; NETWORK BEHAVIORS; O-GLYCANS; O-GLYCOSYLATION; O-LINKED; PATTERN MATCHING ALGORITHMS; POST-TRANSLATIONAL MODIFICATIONS;

ENZYMES;

BETA 1,4 GALACTOSYLTRANSFERASE; EPITOPE; GALACTOSYLTRANSFERASE; GLYCOSYLTRANSFERASE; MUCIN; N ACETYLGLUCOSAMINYLTRANSFERASE; SULFOTRANSFERASE; UNCLASSIFIED DRUG; POLYSACCHARIDE;

ALGORITHM; ARTICLE; BIOSYNTHESIS; COMPUTER LANGUAGE; COMPUTER MODEL; COMPUTER PREDICTION; DATA ANALYSIS SOFTWARE; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME MECHANISM; GLYCOSYLATION; KNOWLEDGE BASE; ONLINE SYSTEM; PROTEIN EXPRESSION; ANIMAL; BIOLOGICAL MODEL; BIOLOGY; CHEMISTRY; CHO CELL LINE; COMPUTER SIMULATION; CRICETULUS; DEFICIENCY; GENE INACTIVATION; GENETIC ENGINEERING; GENETICS; HUMAN; METABOLISM; NOMENCLATURE; PROTEIN PROCESSING;

ANIMALS; CHO CELLS; COMPUTATIONAL BIOLOGY; COMPUTER SIMULATION; CRICETULUS; GENE KNOCKOUT TECHNIQUES; GENETIC ENGINEERING; GLYCOSYLATION; GLYCOSYLTRANSFERASES; HUMANS; KNOWLEDGE BASES; METABOLIC NETWORKS AND PATHWAYS; MODELS, BIOLOGICAL; MUCINS; POLYSACCHARIDES; PROTEIN PROCESSING, POST-TRANSLATIONAL; TERMINOLOGY AS TOPIC;

EID: 84964780719     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.1004844     Document Type: Article

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