Galactosyltransferase 4 is a major control point for glycan branching in N-linked glycosylation

Journal of Cell Science

Volumn 127, Issue 23, 2014, Pages 5014-5026

  McDonald, Andrew G ^a,b   Hayes, Jerrard M ^a,b   Bezak, Tania ^a,b   Głuchowska, Sonia A ^a   Cosgrave, Eoin F J ^b   Struwe, Weston B ^b   Stroop, Corné J M ^c   Kok, Han ^c   van de Laar, Teun ^c   Rudd, Pauline M ^b   Tipton, Keith F ^a   Davey, Gavin P ^a  

^a TRINITY COLLEGE DUBLIN   (Ireland)

^b NATIONAL INSTITUTE FOR BIOPROCESSING RESEARCH AND TRAINING   (Ireland)

^c NV ORGANON   (Netherlands)

Author keywords

Branching; Chorionic gonadotropin; Galactosyltransferase; Glycosylation; Golgi; hCG

Indexed keywords

CHORIONIC GONADOTROPIN; GALACTOSYLTRANSFERASE; GALACTOSYLTRANSFERASE 4; GLYCAN; N ACETYLGLUCOSAMINE; UNCLASSIFIED DRUG; ALPHA-1,3-MANNOSYLGLYCOPROTEIN BETA-1,4-N-ACETYLGLUCOSAMINYLTRANSFERASE; ISOENZYME; N ACETYLGLUCOSAMINYLTRANSFERASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; COMPUTER MODEL; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN CELL; IN VIVO STUDY; MALE; MAMMAL CELL; MATHEMATICAL MODEL; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN GLYCOSYLATION; QUANTITATIVE ANALYSIS; RAT; TRANS GOLGI NETWORK; ANIMAL; BIOLOGICAL MODEL; CHEMICAL STRUCTURE; CHEMISTRY; CHO CELL LINE; COMPUTER SIMULATION; CRICETULUS; DRUG EFFECTS; GENETIC TRANSFECTION; GENETICS; GLYCOSYLATION; GROWTH, DEVELOPMENT AND AGING; HEK293 CELL LINE; KINETICS; METABOLISM; PROTEIN CONFORMATION; PROTEIN PROCESSING; SEMINAL VESICLE; STRUCTURE ACTIVITY RELATION;

ACETYLGLUCOSAMINE; ANIMALS; CHO CELLS; CHORIONIC GONADOTROPIN; COMPUTER SIMULATION; CRICETULUS; GLYCOSYLATION; HEK293 CELLS; HUMANS; ISOENZYMES; KINETICS; MALE; MODELS, BIOLOGICAL; MODELS, MOLECULAR; N-ACETYLGLUCOSAMINYLTRANSFERASES; PROTEIN CONFORMATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; RATS; SEMINAL VESICLES; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSFECTION;

EID: 84914142511     PISSN: 00219533     EISSN: 14779137     Source Type: Journal    
DOI: 10.1242/jcs.151878     Document Type: Article

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