Chinese hamster ovary (CHO) cells may express six β 4-galactosyltransferases (β4GalTs). Consequences of the loss of functional β4Galt-1, β4GalT-6, or both in CHO glycosylation mutants

Journal of Biological Chemistry

Volumn 276, Issue 17, 2001, Pages 13924-13934

  Lee, JaeHoon ^a   Sundaram, Subha ^a   Shaper, Nancy L ^b   Raju, T Shantha ^c   Stanley, Pamela ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c GENENTECH INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CELLS; CLONING; GENES; MASS SPECTROMETRY; MUTAGENESIS; RADIOISOTOPES;

LECTIN RESISTANCE;

ENZYMES;

BETA4 GALACTOSYLTRANSFERASE; GALACTOSYLTRANSFERASE; GLYCOLIPID; GLYCOPEPTIDE; MEMBRANE PROTEIN; RNA; TRITIUM; UNCLASSIFIED DRUG; BETA 1,4 GALACTOSYLTRANSFERASE I; BETA 1,4 GALACTOSYLTRANSFERASE II; BETA 1,4 GALACTOSYLTRANSFERASE IV; BETA 1,4 GALACTOSYLTRANSFERASE V; BETA-1,4-GALACTOSYLTRANSFERASE I; BETA-1,4-GALACTOSYLTRANSFERASE II; BETA-1,4-GALACTOSYLTRANSFERASE IV; BETA-1,4-GALACTOSYLTRANSFERASE V; BETA4 GALACTOSYLTRANSFERASE III; BETA4 GALACTOSYLTRANSFERASE VI; BETA4-GALACTOSYLTRANSFERASE III; BETA4-GALACTOSYLTRANSFERASE VI; COMPLEMENTARY DNA; GALACTOSE; LECTIN; LIGAND; MESSENGER RNA;

ANIMAL CELL; ARTICLE; CHO CELL; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME GLYCOSYLATION; GENE MUTATION; ISOTOPE LABELING; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; NONHUMAN; NORTHERN BLOTTING; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; THIN LAYER CHROMATOGRAPHY; AFFINITY CHROMATOGRAPHY; AMINO ACID SEQUENCE; ANIMAL; BIOSYNTHESIS; CATTLE; CELL LINE; CHROMATOGRAPHY; EXON; GENE DELETION; GENETIC TRANSFECTION; GENETICS; GLYCOSYLATION; HAMSTER; MASS SPECTROMETRY; METABOLISM; MOLECULAR GENETICS; MUTATION; PHYSIOLOGY; SEQUENCE HOMOLOGY;

ANIMALIA; CRICETINAE; CRICETULUS GRISEUS; MAMMALIA;

AMINO ACID SEQUENCE; ANIMALS; BLOTTING, NORTHERN; CATTLE; CELL LINE; CHO CELLS; CHROMATOGRAPHY; CHROMATOGRAPHY, AFFINITY; CHROMATOGRAPHY, THIN LAYER; CRICETINAE; DNA, COMPLEMENTARY; EXONS; GALACTOSE; GALACTOSYLTRANSFERASES; GENE DELETION; GLYCOLIPIDS; GLYCOPEPTIDES; GLYCOSYLATION; LECTINS; LIGANDS; MOLECULAR SEQUENCE DATA; MUTATION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SEQUENCE HOMOLOGY, AMINO ACID; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; TRANSFECTION;

EID: 0035957957     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M010046200     Document Type: Article

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