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Volumn 35, Issue 12, 2014, Pages 2643-2652

Base excision repair capacity in informing healthspan

Author keywords

[No Author keywords available]

Indexed keywords

DNA; DNA GLYCOSYLTRANSFERASE; XRCC1 PROTEIN;

EID: 84964698664     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgu225     Document Type: Review
Times cited : (34)

References (111)
  • 1
    • 0027278557 scopus 로고
    • Instability and decay of the primary structure of DNA
    • Lindahl, T. (1993) Instability and decay of the primary structure of DNA. Nature, 362, 709-715.
    • (1993) Nature , vol.362 , pp. 709-715
    • Lindahl, T.1
  • 2
    • 0344586043 scopus 로고    scopus 로고
    • Mutagenicity, toxicity and repair of DNA base damage induced by oxidation
    • Bjelland, S. et al. (2003) Mutagenicity, toxicity and repair of DNA base damage induced by oxidation. Mutat. Res., 531, 37-80.
    • (2003) Mutat. Res , vol.531 , pp. 37-80
    • Bjelland, S.1
  • 3
    • 33847007529 scopus 로고    scopus 로고
    • The mechanics of base excision repair, and its relationship to aging and disease
    • Wilson, D.M. 3rd et al. (2007) The mechanics of base excision repair, and its relationship to aging and disease. DNA Repair (Amst)., 6, 544-559.
    • (2007) DNA Repair (Amst) , vol.6 , pp. 544-559
    • Wilson, D.M.1
  • 4
    • 84886878031 scopus 로고    scopus 로고
    • The two faces of DNA repair: disease and therapy
    • Vindigni, A. et al. (2013) The two faces of DNA repair: disease and therapy. Mo. Med., 110, 314-319.
    • (2013) Mo. Med , vol.110 , pp. 314-319
    • Vindigni, A.1
  • 5
    • 2942523593 scopus 로고    scopus 로고
    • Endogenous DNA damage in humans: a review of quantitative data
    • De Bont, R. et al. (2004) Endogenous DNA damage in humans: a review of quantitative data. Mutagenesis, 19, 169-185.
    • (2004) Mutagenesis , vol.19 , pp. 169-185
    • De Bont, R.1
  • 6
    • 84902074659 scopus 로고    scopus 로고
    • Ribonucleotides in DNA: origins, repair and consequences
    • Williams, J.S. et al. (2014) Ribonucleotides in DNA: origins, repair and consequences. DNA Repair (Amst)., 19, 27-37.
    • (2014) DNA Repair (Amst) , vol.19 , pp. 27-37
    • Williams, J.S.1
  • 7
    • 3042536878 scopus 로고    scopus 로고
    • Ab initio study of the prototropic tautomerism of cytosine and guanine and their contribution to spontaneous point mutations
    • Podolyan, Y. et al. (2003) Ab initio study of the prototropic tautomerism of cytosine and guanine and their contribution to spontaneous point mutations. Int. J. Mol. Sci., 4, 410-421.
    • (2003) Int. J. Mol. Sci , vol.4 , pp. 410-421
    • Podolyan, Y.1
  • 8
    • 0015493356 scopus 로고
    • Acidic hydrolysis of deoxycytidine and deoxyuridine derivatives. The general mechanism of deoxyribonucleoside hydrolysis
    • Shapiro, R. et al. (1972) Acidic hydrolysis of deoxycytidine and deoxyuridine derivatives. The general mechanism of deoxyribonucleoside hydrolysis. Biochemistry, 11, 23-29.
    • (1972) Biochemistry , vol.11 , pp. 23-29
    • Shapiro, R.1
  • 9
    • 0015753524 scopus 로고
    • Heat-induced depyrimidination of deoxyribonucleic acid in neutral solution
    • Lindahl, T. et al. (1973) Heat-induced depyrimidination of deoxyribonucleic acid in neutral solution. Biochemistry, 12, 5151-5154.
    • (1973) Biochemistry , vol.12 , pp. 5151-5154
    • Lindahl, T.1
  • 10
    • 0033152195 scopus 로고    scopus 로고
    • Endogenous apurinic/apyrimidinic sites in genomic DNA of mammalian tissues
    • Nakamura, J. et al. (1999) Endogenous apurinic/apyrimidinic sites in genomic DNA of mammalian tissues. Cancer Res., 59, 2522-2526.
    • (1999) Cancer Res , vol.59 , pp. 2522-2526
    • Nakamura, J.1
  • 11
    • 3042537834 scopus 로고    scopus 로고
    • Oxidative DNA damage background estimated by a system model of base excision repair
    • Sokhansanj, B.A. et al. (2004) Oxidative DNA damage background estimated by a system model of base excision repair. Free Radic. Biol. Med., 37, 422-427.
    • (2004) Free Radic. Biol. Med , vol.37 , pp. 422-427
    • Sokhansanj, B.A.1
  • 12
    • 0348140585 scopus 로고    scopus 로고
    • Abasic sites in DNA: repair and biological consequences in Saccharomyces cerevisiae
    • Boiteux, S. et al. (2004) Abasic sites in DNA: repair and biological consequences in Saccharomyces cerevisiae. DNA Repair (Amst)., 3, 1-12.
    • (2004) DNA Repair (Amst) , vol.3 , pp. 1-12
    • Boiteux, S.1
  • 13
    • 0025344222 scopus 로고
    • A sensitive genetic assay for the detection of cytosine deamination: determination of rate constants and the activation energy
    • Frederico, L.A. et al. (1990) A sensitive genetic assay for the detection of cytosine deamination: determination of rate constants and the activation energy. Biochemistry, 29, 2532-2537.
    • (1990) Biochemistry , vol.29 , pp. 2532-2537
    • Frederico, L.A.1
  • 14
    • 77953006634 scopus 로고    scopus 로고
    • The mutation spectrum revealed by paired genome sequences from a lung cancer patient
    • Lee, W. et al. (2010) The mutation spectrum revealed by paired genome sequences from a lung cancer patient. Nature, 465, 473-477.
    • (2010) Nature , vol.465 , pp. 473-477
    • Lee, W.1
  • 15
    • 84856233300 scopus 로고    scopus 로고
    • Balancing repair and tolerance of DNA damage caused by alkylating agents
    • Fu, D. et al. (2012) Balancing repair and tolerance of DNA damage caused by alkylating agents. Nat. Rev. Cancer, 12, 104-120.
    • (2012) Nat. Rev. Cancer , vol.12 , pp. 104-120
    • Fu, D.1
  • 16
    • 0020341190 scopus 로고
    • Nonenzymatic methylation of DNA by the intracellular methyl group donor S-adenosyl-L-methionine is a potentially mutagenic reaction
    • Rydberg, B. et al. (1982) Nonenzymatic methylation of DNA by the intracellular methyl group donor S-adenosyl-L-methionine is a potentially mutagenic reaction. EMBO J., 1, 211-216.
    • (1982) EMBO J , vol.1 , pp. 211-216
    • Rydberg, B.1
  • 17
    • 0242608621 scopus 로고    scopus 로고
    • Pathways of oxidative damage
    • Imlay, J.A. (2003) Pathways of oxidative damage. Annu. Rev. Microbiol., 57, 395-418.
    • (2003) Annu. Rev. Microbiol , vol.57 , pp. 395-418
    • Imlay, J.A.1
  • 18
    • 0027974132 scopus 로고
    • Assays of oxidative DNA damage biomarkers 8-oxo-2'-deoxyguanosine and 8-oxoguanine in nuclear DNA and biological fluids by high-performance liquid chromatography with electrochemical detection
    • Shigenaga, M.K. et al. (1994) Assays of oxidative DNA damage biomarkers 8-oxo-2'-deoxyguanosine and 8-oxoguanine in nuclear DNA and biological fluids by high-performance liquid chromatography with electrochemical detection. Methods Enzymol., 234, 16-33.
    • (1994) Methods Enzymol , vol.234 , pp. 16-33
    • Shigenaga, M.K.1
  • 19
    • 0027324378 scopus 로고
    • Mutagenesis by 8-oxoguanine: an enemy within
    • Grollman, A.P. et al. (1993) Mutagenesis by 8-oxoguanine: an enemy within. Trends Genet., 9, 246-249.
    • (1993) Trends Genet , vol.9 , pp. 246-249
    • Grollman, A.P.1
  • 20
    • 84867466090 scopus 로고    scopus 로고
    • Oxidatively induced DNA damage: mechanisms, repair and disease
    • Dizdaroglu, M. (2012) Oxidatively induced DNA damage: mechanisms, repair and disease. Cancer Lett., 327, 26-47.
    • (2012) Cancer Lett , vol.327 , pp. 26-47
    • Dizdaroglu, M.1
  • 21
    • 84867452253 scopus 로고    scopus 로고
    • Pathways for repairing and tolerating the spectrum of oxidative DNA lesions
    • Berquist, B.R. et al. (2012) Pathways for repairing and tolerating the spectrum of oxidative DNA lesions. Cancer Lett., 327, 61-72.
    • (2012) Cancer Lett , vol.327 , pp. 61-72
    • Berquist, B.R.1
  • 22
    • 0032907527 scopus 로고    scopus 로고
    • Molecular epidemiology of human cancer risk: gene-environment interactions and p53 mutation spectrum in human lung cancer
    • Bennett, W.P. et al. (1999) Molecular epidemiology of human cancer risk: gene-environment interactions and p53 mutation spectrum in human lung cancer. J. Pathol., 187, 8-18.
    • (1999) J. Pathol , vol.187 , pp. 8-18
    • Bennett, W.P.1
  • 23
    • 84895784747 scopus 로고    scopus 로고
    • Mechanisms of base substitution mutagenesis in cancer genomes
    • Bacolla, A. et al. (2014) Mechanisms of base substitution mutagenesis in cancer genomes. Genes (Basel)., 5, 108-146.
    • (2014) Genes (Basel) , vol.5 , pp. 108-146
    • Bacolla, A.1
  • 24
    • 33747884339 scopus 로고    scopus 로고
    • DNA damage-induced cell death by apoptosis
    • Roos, W.P. et al. (2006) DNA damage-induced cell death by apoptosis. Trends Mol. Med., 12, 440-450.
    • (2006) Trends Mol. Med , vol.12 , pp. 440-450
    • Roos, W.P.1
  • 25
    • 84897531574 scopus 로고    scopus 로고
    • The biogenesis of chromosome translocations
    • Roukos, V. et al. (2014) The biogenesis of chromosome translocations. Nat. Cell Biol., 16, 293-300.
    • (2014) Nat. Cell Biol , vol.16 , pp. 293-300
    • Roukos, V.1
  • 27
    • 84876016461 scopus 로고    scopus 로고
    • Mammalian base excision repair: the forgotten archangel
    • Dianov, G.L. et al. (2013) Mammalian base excision repair: the forgotten archangel. Nucleic Acids Res., 41, 3483-3490.
    • (2013) Nucleic Acids Res , vol.41 , pp. 3483-3490
    • Dianov, G.L.1
  • 28
    • 80053206516 scopus 로고    scopus 로고
    • Single Qdot-labeled glycosylase molecules use a wedge amino acid to probe for lesions while scanning along DNA
    • Dunn, A.R. et al. (2011) Single Qdot-labeled glycosylase molecules use a wedge amino acid to probe for lesions while scanning along DNA. Nucleic Acids Res., 39, 7487-7498.
    • (2011) Nucleic Acids Res , vol.39 , pp. 7487-7498
    • Dunn, A.R.1
  • 29
    • 1342324026 scopus 로고    scopus 로고
    • DNA glycosylase recognition and catalysis
    • Fromme, J.C. et al. (2004) DNA glycosylase recognition and catalysis. Curr. Opin. Struct. Biol., 14, 43-49.
    • (2004) Curr. Opin. Struct. Biol , vol.14 , pp. 43-49
    • Fromme, J.C.1
  • 30
    • 38049112778 scopus 로고    scopus 로고
    • Early steps in the DNA base excision/single-strand interruption repair pathway in mammalian cells
    • Hegde, M.L. et al. (2008) Early steps in the DNA base excision/single-strand interruption repair pathway in mammalian cells. Cell Res., 18, 27-47.
    • (2008) Cell Res , vol.18 , pp. 27-47
    • Hegde, M.L.1
  • 31
    • 0037090332 scopus 로고    scopus 로고
    • Mechanistic comparisons among base excision repair glycosylases
    • Dodson, M.L. et al. (2002) Mechanistic comparisons among base excision repair glycosylases. Free Radic. Biol. Med., 32, 678-682.
    • (2002) Free Radic. Biol. Med , vol.32 , pp. 678-682
    • Dodson, M.L.1
  • 32
    • 3242710517 scopus 로고    scopus 로고
    • AP endonuclease-independent DNA base excision repair in human cells
    • Wiederhold, L. et al. (2004) AP endonuclease-independent DNA base excision repair in human cells. Mol. Cell, 15, 209-220.
    • (2004) Mol. Cell , vol.15 , pp. 209-220
    • Wiederhold, L.1
  • 33
    • 0033554862 scopus 로고    scopus 로고
    • Human apurinic/apyrimidinic endonuclease is processive
    • Carey, D.C. et al. (1999) Human apurinic/apyrimidinic endonuclease is processive. Biochemistry, 38, 16553-16560.
    • (1999) Biochemistry , vol.38 , pp. 16553-16560
    • Carey, D.C.1
  • 34
    • 0030740948 scopus 로고    scopus 로고
    • Interaction of human apurinic endonuclease and DNA polymerase beta in the base excision repair pathway
    • Bennett, R.A. et al. (1997) Interaction of human apurinic endonuclease and DNA polymerase beta in the base excision repair pathway. Proc. Natl Acad. Sci. USA, 94, 7166-7169.
    • (1997) Proc. Natl Acad. Sci. USA , vol.94 , pp. 7166-7169
    • Bennett, R.A.1
  • 35
    • 38049183244 scopus 로고    scopus 로고
    • XRCC1 and DNA polymerase beta in cellular protection against cytotoxic DNA single-strand breaks
    • Horton, J.K. et al. (2008) XRCC1 and DNA polymerase beta in cellular protection against cytotoxic DNA single-strand breaks. Cell Res., 18, 48-63.
    • (2008) Cell Res , vol.18 , pp. 48-63
    • Horton, J.K.1
  • 36
    • 33646092313 scopus 로고    scopus 로고
    • Roles of DNA ligase III and XRCC1 in regulating the switch between short patch and long patch BER
    • Petermann, E. et al. (2006) Roles of DNA ligase III and XRCC1 in regulating the switch between short patch and long patch BER. DNA Repair (Amst)., 5, 544-555.
    • (2006) DNA Repair (Amst) , vol.5 , pp. 544-555
    • Petermann, E.1
  • 37
    • 33646859065 scopus 로고    scopus 로고
    • Roles of base excision repair subpathways in correcting oxidized abasic sites in DNA
    • Sung, J.S. et al. (2006) Roles of base excision repair subpathways in correcting oxidized abasic sites in DNA. FEBS J., 273, 1620-1629.
    • (2006) FEBS J , vol.273 , pp. 1620-1629
    • Sung, J.S.1
  • 38
    • 79957456954 scopus 로고    scopus 로고
    • Base excision repair and lesion-dependent subpathways for repair of oxidative DNA damage
    • Svilar, D. et al. (2011) Base excision repair and lesion-dependent subpathways for repair of oxidative DNA damage. Antioxid. Redox Signal., 14, 2491-2507.
    • (2011) Antioxid. Redox Signal , vol.14 , pp. 2491-2507
    • Svilar, D.1
  • 39
    • 0032516831 scopus 로고    scopus 로고
    • Mammalian abasic site base excision repair. Identification of the reaction sequence and rate-determining steps
    • Srivastava, D.K. et al. (1998) Mammalian abasic site base excision repair. Identification of the reaction sequence and rate-determining steps. J. Biol. Chem., 273, 21203-21209.
    • (1998) J. Biol. Chem , vol.273 , pp. 21203-21209
    • Srivastava, D.K.1
  • 40
    • 0037089147 scopus 로고    scopus 로고
    • A quantitative model of human DNA base excision repair
    • Sokhansanj, B.A. et al. (2002) A quantitative model of human DNA base excision repair. I. Mechanistic insights. Nucleic Acids Res., 30, 1817-1825.
    • (2002) I. Mechanistic insights. Nucleic Acids Res , vol.30 , pp. 1817-1825
    • Sokhansanj, B.A.1
  • 41
    • 0034659935 scopus 로고    scopus 로고
    • The lyase activity of the DNA repair protein betapolymerase protects from DNA-damage-induced cytotoxicity
    • Sobol, R.W. et al. (2000) The lyase activity of the DNA repair protein betapolymerase protects from DNA-damage-induced cytotoxicity. Nature, 405, 807-810.
    • (2000) Nature , vol.405 , pp. 807-810
    • Sobol, R.W.1
  • 42
    • 0034801478 scopus 로고    scopus 로고
    • Counteracting spontaneous transformation via overexpression of rate-limiting DNA base excision repair enzymes
    • Frosina, G. (2001) Counteracting spontaneous transformation via overexpression of rate-limiting DNA base excision repair enzymes. Carcinogenesis, 22, 1335-1341.
    • (2001) Carcinogenesis , vol.22 , pp. 1335-1341
    • Frosina, G.1
  • 43
    • 0033923815 scopus 로고    scopus 로고
    • Requirement for human AP endonuclease 1 for repair of 3'-blocking damage at DNA single-strand breaks induced by reactive oxygen species
    • Izumi, T. et al. (2000) Requirement for human AP endonuclease 1 for repair of 3'-blocking damage at DNA single-strand breaks induced by reactive oxygen species. Carcinogenesis, 21, 1329-1334.
    • (2000) Carcinogenesis , vol.21 , pp. 1329-1334
    • Izumi, T.1
  • 44
    • 0034725720 scopus 로고    scopus 로고
    • ATP for the DNA ligation step in base excision repair is generated from poly(ADP-ribose)
    • Oei, S.L. et al. (2000) ATP for the DNA ligation step in base excision repair is generated from poly(ADP-ribose). J. Biol. Chem., 275, 23234-23239.
    • (2000) J. Biol. Chem , vol.275 , pp. 23234-23239
    • Oei, S.L.1
  • 45
    • 0014421995 scopus 로고
    • Defective repair replication of DNA in xeroderma pigmentosum
    • Cleaver, J.E. (1968) Defective repair replication of DNA in xeroderma pigmentosum. Nature, 218, 652-656.
    • (1968) Nature , vol.218 , pp. 652-656
    • Cleaver, J.E.1
  • 47
    • 79956210253 scopus 로고    scopus 로고
    • Variation in base excision repair capacity
    • Wilson, D.M. 3rd et al. (2011) Variation in base excision repair capacity. Mutat. Res., 711, 100-112.
    • (2011) Mutat. Res , vol.711 , pp. 100-112
    • Wilson, D.M.1
  • 48
    • 0036478899 scopus 로고    scopus 로고
    • Inherited variants of MYH associated with somatic G:C→T:A mutations in colorectal tumors
    • Al-Tassan, N. et al. (2002) Inherited variants of MYH associated with somatic G:C→T:A mutations in colorectal tumors. Nat. Genet., 30, 227-232.
    • (2002) Nat. Genet , vol.30 , pp. 227-232
    • Al-Tassan, N.1
  • 49
    • 0142092610 scopus 로고    scopus 로고
    • Human uracil-DNA glycosylase deficiency associated with profoundly impaired immunoglobulin class-switch recombination
    • Imai, K. et al. (2003) Human uracil-DNA glycosylase deficiency associated with profoundly impaired immunoglobulin class-switch recombination. Nat. Immunol., 4, 1023-1028.
    • (2003) Nat. Immunol , vol.4 , pp. 1023-1028
    • Imai, K.1
  • 50
    • 0034785531 scopus 로고    scopus 로고
    • The gene mutated in ataxia-ocular apraxia 1 encodes the new HIT/Zn-finger protein aprataxin
    • Moreira, M.C. et al. (2001) The gene mutated in ataxia-ocular apraxia 1 encodes the new HIT/Zn-finger protein aprataxin. Nat. Genet., 29, 189-193.
    • (2001) Nat. Genet , vol.29 , pp. 189-193
    • Moreira, M.C.1
  • 51
    • 18644386254 scopus 로고    scopus 로고
    • Mutation of TDP1, encoding a topoisomerase I-dependent DNA damage repair enzyme, in spinocerebellar ataxia with axonal neuropathy
    • Takashima, H. et al. (2002) Mutation of TDP1, encoding a topoisomerase I-dependent DNA damage repair enzyme, in spinocerebellar ataxia with axonal neuropathy. Nat. Genet., 32, 267-272.
    • (2002) Nat. Genet , vol.32 , pp. 267-272
    • Takashima, H.1
  • 52
    • 77649188409 scopus 로고    scopus 로고
    • Mutations in PNKP cause microcephaly, seizures and defects in DNA repair
    • Shen, J. et al. (2010) Mutations in PNKP cause microcephaly, seizures and defects in DNA repair. Nat. Genet., 42, 245-249.
    • (2010) Nat. Genet , vol.42 , pp. 245-249
    • Shen, J.1
  • 53
    • 48249095920 scopus 로고    scopus 로고
    • Single-strand break repair and genetic disease
    • Caldecott, K.W. (2008) Single-strand break repair and genetic disease. Nat. Rev. Genet., 9, 619-631.
    • (2008) Nat. Rev. Genet , vol.9 , pp. 619-631
    • Caldecott, K.W.1
  • 54
    • 46149083468 scopus 로고    scopus 로고
    • Base excision repair, aging and health span
    • Xu, G. et al. (2008) Base excision repair, aging and health span. Mech. Ageing Dev., 129, 366-382.
    • (2008) Mech. Ageing Dev , vol.129 , pp. 366-382
    • Xu, G.1
  • 55
    • 84857043015 scopus 로고    scopus 로고
    • Haploinsufficiency in mouse models of DNA repair deficiency: modifiers of penetrance
    • Cabelof, D.C. (2012) Haploinsufficiency in mouse models of DNA repair deficiency: modifiers of penetrance. Cell. Mol. Life Sci., 69, 727-740.
    • (2012) Cell. Mol. Life Sci , vol.69 , pp. 727-740
    • Cabelof, D.C.1
  • 56
    • 84912080867 scopus 로고    scopus 로고
    • Oxidative DNA damage in disease-insights gained from base excision repair glycosylase-deficient mouse models
    • Sampath, H. (2014) Oxidative DNA damage in disease-insights gained from base excision repair glycosylase-deficient mouse models. Environ. Mol. Mutagen, 55, 689-703.
    • (2014) Environ. Mol. Mutagen , vol.55 , pp. 689-703
    • Sampath, H.1
  • 57
    • 79951810964 scopus 로고    scopus 로고
    • Embryonic lethal phenotype reveals a function of TDG in maintaining epigenetic stability
    • Cortázar, D. et al. (2011) Embryonic lethal phenotype reveals a function of TDG in maintaining epigenetic stability. Nature, 470, 419-423.
    • (2011) Nature , vol.470 , pp. 419-423
    • Cortázar, D.1
  • 58
    • 84858120925 scopus 로고    scopus 로고
    • Regulation of DNA glycosylases and their role in limiting disease
    • Sampath, H. et al. (2012) Regulation of DNA glycosylases and their role in limiting disease. Free Radic. Res., 46, 460-478.
    • (2012) Free Radic. Res , vol.46 , pp. 460-478
    • Sampath, H.1
  • 59
    • 58849095932 scopus 로고    scopus 로고
    • Aag-initiated base excision repair drives alkylation-induced retinal degeneration in mice
    • Meira, L.B. et al. (2009) Aag-initiated base excision repair drives alkylation-induced retinal degeneration in mice. Proc. Natl Acad. Sci. USA, 106, 888-893.
    • (2009) Proc. Natl Acad. Sci. USA , vol.106 , pp. 888-893
    • Meira, L.B.1
  • 60
    • 46749127004 scopus 로고    scopus 로고
    • DNA damage induced by chronic inflammation contributes to colon carcinogenesis in mice
    • Meira, L.B. et al. (2008) DNA damage induced by chronic inflammation contributes to colon carcinogenesis in mice. J. Clin. Invest., 118, 2516-2525.
    • (2008) J. Clin. Invest , vol.118 , pp. 2516-2525
    • Meira, L.B.1
  • 61
    • 78649767885 scopus 로고    scopus 로고
    • 6-methylguanine-DNA methyltransferase protect against methylation-induced colon carcinogenesis
    • 6-methylguanine-DNA methyltransferase protect against methylation-induced colon carcinogenesis. Carcinogenesis, 31, 2111-2117.
    • (2010) Carcinogenesis , vol.31 , pp. 2111-2117
    • Wirtz, S.1
  • 62
    • 84863545485 scopus 로고    scopus 로고
    • DNA repair is indispensable for survival after acute inflammation
    • Calvo, J.A. et al. (2012) DNA repair is indispensable for survival after acute inflammation. J. Clin. Invest., 122, 2680-2689.
    • (2012) J. Clin. Invest , vol.122 , pp. 2680-2689
    • Calvo, J.A.1
  • 63
    • 0033539610 scopus 로고    scopus 로고
    • Accumulation of premutagenic DNA lesions in mice defective in removal of oxidative base damage
    • Klungland, A. et al. (1999) Accumulation of premutagenic DNA lesions in mice defective in removal of oxidative base damage. Proc. Natl Acad. Sci. USA, 96, 13300-13305.
    • (1999) Proc. Natl Acad. Sci. USA , vol.96 , pp. 13300-13305
    • Klungland, A.1
  • 64
    • 48149086418 scopus 로고    scopus 로고
    • Increased susceptibility of chronic ulcerative colitisinduced carcinoma development in DNA repair enzyme Ogg1 deficient mice
    • Liao, J. et al. (2008) Increased susceptibility of chronic ulcerative colitisinduced carcinoma development in DNA repair enzyme Ogg1 deficient mice. Mol. Carcinog., 47, 638-646.
    • (2008) Mol. Carcinog , vol.47 , pp. 638-646
    • Liao, J.1
  • 65
    • 3042739635 scopus 로고    scopus 로고
    • Accumulation of the oxidative base lesion 8-hydroxyguanine in DNA of tumor-prone mice defective in both the Myh and Ogg1 DNA glycosylases
    • Russo, M.T. et al. (2004) Accumulation of the oxidative base lesion 8-hydroxyguanine in DNA of tumor-prone mice defective in both the Myh and Ogg1 DNA glycosylases. Cancer Res., 64, 4411-4414.
    • (2004) Cancer Res , vol.64 , pp. 4411-4414
    • Russo, M.T.1
  • 66
    • 0035879043 scopus 로고    scopus 로고
    • Heterozygosity for the mouse Apex gene results in phenotypes associated with oxidative stress
    • Meira, L.B. et al. (2001) Heterozygosity for the mouse Apex gene results in phenotypes associated with oxidative stress. Cancer Res., 61, 5552-5557.
    • (2001) Cancer Res , vol.61 , pp. 5552-5557
    • Meira, L.B.1
  • 67
    • 4444294284 scopus 로고    scopus 로고
    • Spontaneous mutagenesis is enhanced in Apex heterozygous mice
    • Huamani, J. et al. (2004) Spontaneous mutagenesis is enhanced in Apex heterozygous mice. Mol. Cell. Biol., 24, 8145-8153.
    • (2004) Mol. Cell. Biol , vol.24 , pp. 8145-8153
    • Huamani, J.1
  • 68
    • 81355160487 scopus 로고    scopus 로고
    • Age-related instability in spermatogenic cell nuclear and mitochondrial DNA obtained from Apex1 heterozygous mice
    • Vogel, K.S. et al. (2011) Age-related instability in spermatogenic cell nuclear and mitochondrial DNA obtained from Apex1 heterozygous mice. Mol. Reprod. Dev., 78, 906-919.
    • (2011) Mol. Reprod. Dev , vol.78 , pp. 906-919
    • Vogel, K.S.1
  • 69
    • 67349179226 scopus 로고    scopus 로고
    • Oxidative stress alters base excision repair pathway and increases apoptotic response in apurinic/apyrimidinic endonuclease 1/redox factor-1 haploinsufficient mice
    • Unnikrishnan, A. et al. (2009) Oxidative stress alters base excision repair pathway and increases apoptotic response in apurinic/apyrimidinic endonuclease 1/redox factor-1 haploinsufficient mice. Free Radic. Biol. Med., 46, 1488-1499.
    • (2009) Free Radic. Biol. Med , vol.46 , pp. 1488-1499
    • Unnikrishnan, A.1
  • 70
    • 0026714672 scopus 로고
    • Redox activation of Fos-Jun DNA binding activity is mediated by a DNA repair enzyme
    • Xanthoudakis, S. et al. (1992) Redox activation of Fos-Jun DNA binding activity is mediated by a DNA repair enzyme. EMBO J., 11, 3323-3335.
    • (1992) EMBO J , vol.11 , pp. 3323-3335
    • Xanthoudakis, S.1
  • 71
    • 7244248654 scopus 로고    scopus 로고
    • Apurinic/apyrimidinic endonuclease 1 regulates endothelial NO production and vascular tone
    • Jeon, B.H. et al. (2004) Apurinic/apyrimidinic endonuclease 1 regulates endothelial NO production and vascular tone. Circ. Res., 95, 902-910.
    • (2004) Circ. Res , vol.95 , pp. 902-910
    • Jeon, B.H.1
  • 72
    • 84859882113 scopus 로고    scopus 로고
    • Regulation of mouse-renin gene by apurinic/apyrimidinic-endonuclease 1 (APE1/Ref-1) via recruitment of histone deacetylase 1 corepressor complex
    • Sengupta, S. et al. (2012) Regulation of mouse-renin gene by apurinic/apyrimidinic-endonuclease 1 (APE1/Ref-1) via recruitment of histone deacetylase 1 corepressor complex. J. Hypertens., 30, 917-925.
    • (2012) J. Hypertens , vol.30 , pp. 917-925
    • Sengupta, S.1
  • 73
    • 0034654379 scopus 로고    scopus 로고
    • Neonatal lethality with abnormal neurogenesis in mice deficient in DNA polymerase beta
    • Sugo, N. et al. (2000) Neonatal lethality with abnormal neurogenesis in mice deficient in DNA polymerase beta. EMBO J., 19, 1397-1404.
    • (2000) EMBO J , vol.19 , pp. 1397-1404
    • Sugo, N.1
  • 74
    • 0036714327 scopus 로고    scopus 로고
    • Induction of DNA polymerase beta-dependent base excision repair in response to oxidative stress in vivo
    • Cabelof, D.C. et al. (2002) Induction of DNA polymerase beta-dependent base excision repair in response to oxidative stress in vivo. Carcinogenesis, 23, 1419-1425.
    • (2002) Carcinogenesis , vol.23 , pp. 1419-1425
    • Cabelof, D.C.1
  • 75
    • 0141731310 scopus 로고    scopus 로고
    • Base excision repair deficiency caused by polymerase beta haploinsufficiency: accelerated DNA damage and increased mutational response to carcinogens
    • Cabelof, D.C. et al. (2003) Base excision repair deficiency caused by polymerase beta haploinsufficiency: accelerated DNA damage and increased mutational response to carcinogens. Cancer Res., 63, 5799-5807.
    • (2003) Cancer Res , vol.63 , pp. 5799-5807
    • Cabelof, D.C.1
  • 76
    • 4344701997 scopus 로고    scopus 로고
    • Imbalanced base excision repair in response to folate deficiency is accelerated by polymerase beta haploinsufficiency
    • Cabelof, D.C. et al. (2004) Imbalanced base excision repair in response to folate deficiency is accelerated by polymerase beta haploinsufficiency. J. Biol. Chem., 279, 36504-36513.
    • (2004) J. Biol. Chem , vol.279 , pp. 36504-36513
    • Cabelof, D.C.1
  • 77
    • 33747878572 scopus 로고    scopus 로고
    • Haploinsufficiency in DNA polymerase beta increases cancer risk with age and alters mortality rate
    • Cabelof, D.C. et al. (2006) Haploinsufficiency in DNA polymerase beta increases cancer risk with age and alters mortality rate. Cancer Res., 66, 7460-7465.
    • (2006) Cancer Res , vol.66 , pp. 7460-7465
    • Cabelof, D.C.1
  • 78
    • 55549124181 scopus 로고    scopus 로고
    • Mutagenesis is elevated in male germ cells obtained from DNA polymerase-beta heterozygous mice
    • Allen, D. et al. (2008) Mutagenesis is elevated in male germ cells obtained from DNA polymerase-beta heterozygous mice. Biol. Reprod., 79, 824-831.
    • (2008) Biol. Reprod , vol.79 , pp. 824-831
    • Allen, D.1
  • 79
    • 79952697454 scopus 로고    scopus 로고
    • DNA polymerase beta is critical for genomic stability of sperm cells
    • Kidane, D. et al. (2011) DNA polymerase beta is critical for genomic stability of sperm cells. DNA Repair (Amst)., 10, 390-397.
    • (2011) DNA Repair (Amst) , vol.10 , pp. 390-397
    • Kidane, D.1
  • 80
    • 77953493760 scopus 로고    scopus 로고
    • Folate deficiency provides protection against colon carcinogenesis in DNA polymerase beta haploinsufficient mice
    • Ventrella-Lucente, L.F. et al. (2010) Folate deficiency provides protection against colon carcinogenesis in DNA polymerase beta haploinsufficient mice. J. Biol. Chem., 285, 19246-19258.
    • (2010) J. Biol. Chem , vol.285 , pp. 19246-19258
    • Ventrella-Lucente, L.F.1
  • 81
    • 0028059099 scopus 로고
    • Deletion of a DNA polymerase beta gene segment in T cells using cell type-specific gene targeting
    • Gu, H. et al. (1994) Deletion of a DNA polymerase beta gene segment in T cells using cell type-specific gene targeting. Science, 265, 103-106.
    • (1994) Science , vol.265 , pp. 103-106
    • Gu, H.1
  • 82
    • 84892494500 scopus 로고    scopus 로고
    • Mutation of POLB causes lupus in mice
    • Senejani, A.G. et al. (2014) Mutation of POLB causes lupus in mice. Cell Rep., 6, 1-8.
    • (2014) Cell Rep , vol.6 , pp. 1-8
    • Senejani, A.G.1
  • 83
    • 0033561152 scopus 로고    scopus 로고
    • Requirement for the Xrcc1 DNA base excision repair gene during early mouse development
    • Tebbs, R.S. et al. (1999) Requirement for the Xrcc1 DNA base excision repair gene during early mouse development. Dev. Biol., 208, 513-529.
    • (1999) Dev. Biol , vol.208 , pp. 513-529
    • Tebbs, R.S.1
  • 84
    • 80054053350 scopus 로고    scopus 로고
    • XRCC1 haploinsufficiency in mice has little effect on aging, but adversely modifies exposure-dependent susceptibility
    • McNeill, D.R. et al. (2011) XRCC1 haploinsufficiency in mice has little effect on aging, but adversely modifies exposure-dependent susceptibility. Nucleic Acids Res., 39, 7992-8004.
    • (2011) Nucleic Acids Res , vol.39 , pp. 7992-8004
    • McNeill, D.R.1
  • 85
    • 84888134794 scopus 로고    scopus 로고
    • Base excision repair in the mammalian brain: implication for age related neurodegeneration
    • Sykora, P. et al. (2013) Base excision repair in the mammalian brain: implication for age related neurodegeneration. Mech. Ageing Dev., 134, 440-448.
    • (2013) Mech. Ageing Dev , vol.134 , pp. 440-448
    • Sykora, P.1
  • 86
    • 80055116358 scopus 로고    scopus 로고
    • XRCC1 suppresses somatic hypermutation and promotes alternative nonhomologous end joining in Igh genes
    • Saribasak, H. et al. (2011) XRCC1 suppresses somatic hypermutation and promotes alternative nonhomologous end joining in Igh genes. J. Exp. Med., 208, 2209-2216.
    • (2011) J. Exp. Med , vol.208 , pp. 2209-2216
    • Saribasak, H.1
  • 87
    • 0345724841 scopus 로고    scopus 로고
    • Rescue of Xrcc1 knockout mouse embryo lethality by transgene-complementation
    • Tebbs, R.S. et al. (2003) Rescue of Xrcc1 knockout mouse embryo lethality by transgene-complementation. DNA Repair (Amst)., 2, 1405-1417.
    • (2003) DNA Repair (Amst) , vol.2 , pp. 1405-1417
    • Tebbs, R.S.1
  • 88
    • 33645116504 scopus 로고    scopus 로고
    • Mouse models of XRCC1 DNA repair polymorphisms and cancer
    • Ladiges, W.C. (2006) Mouse models of XRCC1 DNA repair polymorphisms and cancer. Oncogene, 25, 1612-1619.
    • (2006) Oncogene , vol.25 , pp. 1612-1619
    • Ladiges, W.C.1
  • 89
    • 0021020105 scopus 로고
    • 6-methyl guanine-DNA methyltransferase and uracil-DNA glycosylase in human organs
    • 6-methyl guanine-DNA methyltransferase and uracil-DNA glycosylase in human organs. Carcinogenesis, 4, 1565-1568.
    • (1983) Carcinogenesis , vol.4 , pp. 1565-1568
    • Myrnes, B.1
  • 90
    • 0031864082 scopus 로고    scopus 로고
    • AP endonuclease activity in humans: development of a simple assay and analysis of ten normal individuals
    • Redaelli, A. et al. (1998) AP endonuclease activity in humans: development of a simple assay and analysis of ten normal individuals. Teratog. Carcinog. Mutagen., 18, 17-26.
    • (1998) Teratog. Carcinog. Mutagen , vol.18 , pp. 17-26
    • Redaelli, A.1
  • 91
    • 0033379382 scopus 로고    scopus 로고
    • Age-independency of AP site incision capacity in women
    • Rossi, O. et al. (1999) Age-independency of AP site incision capacity in women. Environ. Mol. Mutagen., 34, 256-259.
    • (1999) Environ. Mol. Mutagen , vol.34 , pp. 256-259
    • Rossi, O.1
  • 92
    • 0033991183 scopus 로고    scopus 로고
    • Analysis of repair of abasic sites in early onset breast cancer patients
    • Rossi, O. et al. (2000) Analysis of repair of abasic sites in early onset breast cancer patients. Int. J. Cancer, 85, 21-26.
    • (2000) Int. J. Cancer , vol.85 , pp. 21-26
    • Rossi, O.1
  • 93
    • 0042832464 scopus 로고    scopus 로고
    • DNA repair activity for oxidative damage and risk of lung cancer
    • Paz-Elizur, T. et al. (2003) DNA repair activity for oxidative damage and risk of lung cancer. J. Natl Cancer Inst., 95, 1312-1319.
    • (2003) J. Natl Cancer Inst , vol.95 , pp. 1312-1319
    • Paz-Elizur, T.1
  • 94
    • 84876846651 scopus 로고    scopus 로고
    • Aag DNA glycosylase promotes alkylation-induced tissue damage mediated by Parp1
    • Calvo, J.A. et al. (2013) Aag DNA glycosylase promotes alkylation-induced tissue damage mediated by Parp1. PLoS Genet., 9, e1003413.
    • (2013) PLoS Genet , vol.9
    • Calvo, J.A.1
  • 95
    • 2442713688 scopus 로고    scopus 로고
    • A molecular beacon assay for measuring base excision repair activities
    • Maksimenko, A. et al. (2004) A molecular beacon assay for measuring base excision repair activities. Biochem. Biophys. Res. Commun., 319, 240-246.
    • (2004) Biochem. Biophys. Res. Commun , vol.319 , pp. 240-246
    • Maksimenko, A.1
  • 96
    • 75149185401 scopus 로고    scopus 로고
    • Use of a molecular beacon to track the activity of base excision repair protein OGG1 in live cells
    • Mirbahai, L. et al. (2010) Use of a molecular beacon to track the activity of base excision repair protein OGG1 in live cells. DNA Repair (Amst)., 9, 144-152.
    • (2010) DNA Repair (Amst) , vol.9 , pp. 144-152
    • Mirbahai, L.1
  • 97
    • 84868286409 scopus 로고    scopus 로고
    • Quantitative, real-time analysis of base excision repair activity in cell lysates utilizing lesion-specific molecular beacons
    • Svilar, D. et al. (2012) Quantitative, real-time analysis of base excision repair activity in cell lysates utilizing lesion-specific molecular beacons. J. Vis. Exp., 6, e4168.
    • (2012) J. Vis. Exp , vol.6
    • Svilar, D.1
  • 98
    • 78649908123 scopus 로고    scopus 로고
    • Age-associated modifications of Base Excision Repair activities in human skin fibroblast extracts
    • Pons, B. et al. (2010) Age-associated modifications of Base Excision Repair activities in human skin fibroblast extracts. Mech. Ageing Dev., 131, 661-665.
    • (2010) Mech. Ageing Dev , vol.131 , pp. 661-665
    • Pons, B.1
  • 99
    • 0032544037 scopus 로고    scopus 로고
    • Generation of a strong mutator phenotype in yeast by imbalanced base excision repair
    • Glassner, B.J. et al. (1998) Generation of a strong mutator phenotype in yeast by imbalanced base excision repair. Proc. Natl Acad. Sci. USA, 95, 9997-10002.
    • (1998) Proc. Natl Acad. Sci. USA , vol.95 , pp. 9997-10002
    • Glassner, B.J.1
  • 100
    • 0026589375 scopus 로고
    • Generation of single-nucleotide repair patches following excision of uracil residues from DNA
    • Dianov, G. et al. (1992) Generation of single-nucleotide repair patches following excision of uracil residues from DNA. Mol. Cell. Biol., 12, 1605-1612.
    • (1992) Mol. Cell. Biol , vol.12 , pp. 1605-1612
    • Dianov, G.1
  • 101
    • 0032029577 scopus 로고    scopus 로고
    • Repair and mutagenic potency of 8-oxoG:A and 8-oxoG:C base pairs in mammalian cells
    • Le Page, F. et al. (1998) Repair and mutagenic potency of 8-oxoG:A and 8-oxoG:C base pairs in mammalian cells. Nucleic Acids Res., 26, 1276-1281.
    • (1998) Nucleic Acids Res , vol.26 , pp. 1276-1281
    • Le Page, F.1
  • 102
    • 84899810741 scopus 로고    scopus 로고
    • Multiplexed DNA repair assays for multiple lesions and multiple doses via transcription inhibition and transcriptional mutagenesis
    • Nagel, Z.D. et al. (2014) Multiplexed DNA repair assays for multiple lesions and multiple doses via transcription inhibition and transcriptional mutagenesis. Proc. Natl Acad. Sci. USA, 111, E1823-E1832.
    • (2014) Proc. Natl Acad. Sci. USA , vol.111 , pp. E1823-E1832
    • Nagel, Z.D.1
  • 103
    • 84864518589 scopus 로고    scopus 로고
    • DNA repair as a biomarker in human biomonitoring studies; further applications of the comet assay
    • Collins, A.R. et al. (2012) DNA repair as a biomarker in human biomonitoring studies; further applications of the comet assay. Mutat. Res., 736, 122-129.
    • (2012) Mutat. Res , vol.736 , pp. 122-129
    • Collins, A.R.1
  • 104
    • 84894240042 scopus 로고    scopus 로고
    • The comet assay as a tool for human biomonitoring studies: the ComNet project
    • Collins, A. et al. (2014) The comet assay as a tool for human biomonitoring studies: the ComNet project. Mutat. Res. Rev. Mutat. Res., 759, 27-39.
    • (2014) Mutat. Res. Rev. Mutat. Res , vol.759 , pp. 27-39
    • Collins, A.1
  • 105
    • 0036150713 scopus 로고    scopus 로고
    • High throughput Comet assay using 96-well plates
    • Kiskinis, E. et al. (2002) High throughput Comet assay using 96-well plates. Mutagenesis, 17, 37-43.
    • (2002) Mutagenesis , vol.17 , pp. 37-43
    • Kiskinis, E.1
  • 106
    • 84867473669 scopus 로고    scopus 로고
    • Detecting chemically modified DNA bases using surface enhanced raman spectroscopy
    • Barhoumi, A. et al. (2011) Detecting chemically modified DNA bases using surface enhanced raman spectroscopy. J. Phys. Chem. Lett., 2, 3118-3123.
    • (2011) J. Phys. Chem. Lett , vol.2 , pp. 3118-3123
    • Barhoumi, A.1
  • 107
    • 0026687249 scopus 로고
    • 4-ethylthymine by the combination of high-performance liquid chromatography prefractionation, 32P postlabeling, and immunoprecipitation
    • 4-ethylthymine by the combination of high-performance liquid chromatography prefractionation, 32P postlabeling, and immunoprecipitation. Cancer Res., 52, 5307-5312.
    • (1992) Cancer Res , vol.52 , pp. 5307-5312
    • Kang, H.I.1
  • 108
    • 0034681176 scopus 로고    scopus 로고
    • A method for detecting abasic sites in living cells: age-dependent changes in base excision repair
    • Atamna, H. et al. (2000) A method for detecting abasic sites in living cells: age-dependent changes in base excision repair. Proc. Natl Acad. Sci. USA, 97, 686-691.
    • (2000) Proc. Natl Acad. Sci. USA , vol.97 , pp. 686-691
    • Atamna, H.1
  • 109
    • 65549163171 scopus 로고    scopus 로고
    • A modified and automated version of the 'Fluorimetric Detection of Alkaline DNA Unwinding' method to quantify formation and repair of DNA strand breaks
    • Moreno-Villanueva, M. et al. (2009) A modified and automated version of the 'Fluorimetric Detection of Alkaline DNA Unwinding' method to quantify formation and repair of DNA strand breaks. BMC Biotechnol., 9, 39.
    • (2009) BMC Biotechnol , vol.9 , pp. 39
    • Moreno-Villanueva, M.1
  • 110
    • 1342288971 scopus 로고    scopus 로고
    • Opinion: Comparative biology of mouse versus human cells: modelling human cancer in mice
    • Rangarajan, A. et al. (2003) Opinion: Comparative biology of mouse versus human cells: modelling human cancer in mice. Nat. Rev. Cancer, 3, 952-959.
    • (2003) Nat. Rev. Cancer , vol.3 , pp. 952-959
    • Rangarajan, A.1
  • 111
    • 0037206612 scopus 로고    scopus 로고
    • On the origin of p53 G:C→ T:A transversions in lung cancers
    • Rodin, S.N. et al. (2002) On the origin of p53 G:C→ T:A transversions in lung cancers. Mutat. Res., 508, 1-19.
    • (2002) Mutat. Res , vol.508 , pp. 1-19
    • Rodin, S.N.1


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