Age-related instability in spermatogenic cell nuclear and mitochondrial DNA obtained from Apex1 heterozygous mice

Molecular Reproduction and Development

Volumn 78, Issue 12, 2011, Pages 906-919

  Vogel, Kristine S ^a   Perez, Marissa ^a   Momand, Jamila R ^a   Acevedo Torres, Karina ^b   Hildreth, Kim ^a   Garcia, Rebecca A ^a   Torres Ramos, Carlos A ^b   Ayala Torres, Sylvette ^b   Prihoda, Thomas J ^a   Mcmahan, C Alex ^a   Walter, Christi A ^a,c,d  

^a Mays Cancer Center at UT Health San Antonio   (United States)

^b UNIVERSITY OF PUERTO RICO   (Puerto Rico)

^c UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^d SOUTH TEXAS VETERANS HEALTH CARE SYSTEM   (United States)

Author keywords

AP endonuclease; Base excision repair; LacI; Mutagenesis; Paternal age; Transgenic mice

Indexed keywords

APEX1 PROTEIN; DNA (APURINIC OR APYRIMIDINIC SITE) LYASE; MITOCHONDRIAL DNA; PROTEIN; TISSUE FACTOR PATHWAY INHIBITOR; UNCLASSIFIED DRUG;

AGE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL NUCLEUS MEMBRANE; DNA DAMAGE; DNA REPAIR; GENOMIC INSTABILITY; GERMLINE MICRONUCLEUS; HETEROZYGOSITY; MALE; MOUSE; MUTAGENESIS; MUTANT; NONHUMAN; PRIORITY JOURNAL; SPERMATOCYTE; TRANSGENE; WILD TYPE;

AGE FACTORS; ANIMALS; APOPTOSIS; CELL NUCLEUS; DNA; DNA DAMAGE; DNA, MITOCHONDRIAL; DNA-(APURINIC OR APYRIMIDINIC SITE) LYASE; HETEROZYGOTE; LOGISTIC MODELS; MALE; MICE; MICE, TRANSGENIC; MUTAGENESIS; SPERMATOGENESIS; SPERMATOZOA;

MUS; MUS MUSCULUS;

EID: 81355160487     PISSN: 1040452X     EISSN: 10982795     Source Type: Journal    
DOI: 10.1002/mrd.21374     Document Type: Article

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