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Volumn 9, Issue 2, 2014, Pages

Fibroblast activation protein (FAP) is essential for the migration of bone marrow mesenchymal stem cells through RhoA activation

Author keywords

[No Author keywords available]

Indexed keywords

FIBROBLAST ACTIVATION PROTEIN; GLUTATHIONE TRANSFERASE; INTERLEUKIN 1BETA; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; SERINE PROTEINASE; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

EID: 84895780919     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0088772     Document Type: Article
Times cited : (66)

References (66)
  • 1
    • 0043073112 scopus 로고    scopus 로고
    • Prolyl peptidases: A serine protease subfamily with high potential for drug discovery
    • DOI 10.1016/S1367-5931(03)00084-X
    • Rosenblum JS, Kozarich JW (2003) Prolyl peptidases: a serine protease subfamily with high potential for drug discovery. Curr Opin Chem Biol 7: 496-504. (Pubitemid 36980841)
    • (2003) Current Opinion in Chemical Biology , vol.7 , Issue.4 , pp. 496-504
    • Rosenblum, J.S.1    Kozarich, J.W.2
  • 3
    • 0005429990 scopus 로고
    • Cell-surface glycoproteins of human sarcomas: Differential expression in normal and malignant tissues and cultured cells
    • Rettig WJ, Garin-Chesa P, Beresford HR, Oettgen HF, Melamed MR, et al. (1988) Cell-surface glycoproteins of human sarcomas: differential expression in normal and malignant tissues and cultured cells. Proc Natl Acad Sci U S A 85: 3110-3114.
    • (1988) Proc Natl Acad Sci U S A , vol.85 , pp. 3110-3114
    • Rettig, W.J.1    Garin-Chesa, P.2    Beresford, H.R.3    Oettgen, H.F.4    Melamed, M.R.5
  • 4
    • 0037318082 scopus 로고    scopus 로고
    • Fibroblast activation protein: Differential expression and serine protease activity in reactive stromal fibroblasts of melanocytic skin tumors
    • DOI 10.1046/j.1523-1747.2003.12035.x
    • Huber MA, Kraut N, Park JE, Schubert RD, Rettig WJ, et al. (2003) Fibroblast activation protein: differential expression and serine protease activity in reactive stromal fibroblasts of melanocytic skin tumors. J Invest Dermatol 120: 182-188. (Pubitemid 36513065)
    • (2003) Journal of Investigative Dermatology , vol.120 , Issue.2 , pp. 182-188
    • Huber, M.A.1    Kraut, N.2    Park, J.E.3    Schubert, R.D.4    Rettig, W.J.5    Peter, R.U.6    Garin-Chesa, P.7
  • 5
    • 0038702525 scopus 로고    scopus 로고
    • Seprase complexes in cellular invasiveness
    • Chen WT, Kelly T (2003) Seprase complexes in cellular invasiveness. Cancer Metastasis Rev 22: 259-269.
    • (2003) Cancer Metastasis Rev , vol.22 , pp. 259-269
    • Chen, W.T.1    Kelly, T.2
  • 6
    • 0037687830 scopus 로고    scopus 로고
    • DPPIV and seprase in cancer invasion and angiogenesis
    • Chen WT (2003) DPPIV and seprase in cancer invasion and angiogenesis. Adv Exp Med Biol 524: 197-203.
    • (2003) Adv Exp Med Biol , vol.524 , pp. 197-203
    • Chen, W.T.1
  • 7
    • 0037102412 scopus 로고    scopus 로고
    • Promotion of tumor growth by murine fibroblast activation protein, a serine protease, in an animal model
    • Cheng JD, Dunbrack RL, Jr., Valianou M, Rogatko A, Alpaugh RK, et al. (2002) Promotion of tumor growth by murine fibroblast activation protein, a serine protease, in an animal model. Cancer Res 62: 4767-4772.
    • (2002) Cancer Res , vol.62 , pp. 4767-4772
    • Cheng, J.D.1    Dunbrack Jr., R.L.2    Valianou, M.3    Rogatko, A.4    Alpaugh, R.K.5
  • 8
    • 15944389319 scopus 로고    scopus 로고
    • Seprase Promotes Rapid Tumor Growth and Increased Microvessel Density in a Mouse Model of Human Breast Cancer
    • DOI 10.1158/0008-5472.CAN-03-3184
    • Huang Y, Wang S, Kelly T (2004) Seprase promotes rapid tumor growth and increased microvessel density in a mouse model of human breast cancer. Cancer Res 64: 2712-2716. (Pubitemid 38500606)
    • (2004) Cancer Research , vol.64 , Issue.8 , pp. 2712-2716
    • Huang, Y.1    Wang, S.2    Kelly, T.3
  • 9
    • 78149298209 scopus 로고    scopus 로고
    • Suppression of antitumor immunity by stromal cells expressing fibroblast activation protein-alpha
    • Kraman M, Bambrough PJ, Arnold JN, Roberts EW, Magiera L, et al. (2010) Suppression of antitumor immunity by stromal cells expressing fibroblast activation protein-alpha. Science 330: 827-830.
    • (2010) Science , vol.330 , pp. 827-830
    • Kraman, M.1    Bambrough, P.J.2    Arnold, J.N.3    Roberts, E.W.4    Magiera, L.5
  • 11
    • 32644446428 scopus 로고    scopus 로고
    • Antiplasmin-cleaving enzyme is a soluble form of fibroblast activation protein
    • DOI 10.1182/blood-2005-08-3452
    • Lee KN, Jackson KW, Christiansen VJ, Lee CS, Chun JG, et al. (2006) Antiplasmin-cleaving enzyme is a soluble form of fibroblast activation protein. Blood 107: 1397-1404. (Pubitemid 43242374)
    • (2006) Blood , vol.107 , Issue.4 , pp. 1397-1404
    • Lee, K.N.1    Jackson, K.W.2    Christiansen, V.J.3    Lee, C.S.4    Chun, J.-G.5    McKee, P.A.6
  • 12
    • 2342447229 scopus 로고    scopus 로고
    • 2-antiplasmin inhibition of fibrin digestion
    • DOI 10.1182/blood-2003-12-4240
    • Lee KN, Jackson KW, Christiansen VJ, Chung KH, McKee PA (2004) A novel plasma proteinase potentiates alpha2-antiplasmin inhibition of fibrin digestion. Blood 103: 3783-3788. (Pubitemid 38596296)
    • (2004) Blood , vol.103 , Issue.10 , pp. 3783-3788
    • Lee, K.N.1    Jackson, K.W.2    Christiansen, V.J.3    Chung, K.H.4    McKee, P.A.5
  • 13
    • 33846018363 scopus 로고    scopus 로고
    • 2-antiplasmin cleaving enzyme on collagen Types I, III, and IV
    • DOI 10.1016/j.abb.2006.11.006, PII S0003986106004371
    • Christiansen VJ, Jackson KW, Lee KN, McKee PA (2007) Effect of fibroblast activation protein and alpha2-antiplasmin cleaving enzyme on collagen types I, III, and IV. Arch Biochem Biophys 457: 177-186. (Pubitemid 46048698)
    • (2007) Archives of Biochemistry and Biophysics , vol.457 , Issue.2 , pp. 177-186
    • Christiansen, V.J.1    Jackson, K.W.2    Lee, K.N.3    McKee, P.A.4
  • 14
    • 0033609816 scopus 로고    scopus 로고
    • A novel protease-docking function of integrin at invadopodia
    • Mueller SC, Ghersi G, Akiyama SK, Sang QX, Howard L, et al. (1999) A novel protease-docking function of integrin at invadopodia. J Biol Chem 274: 24947-24952.
    • (1999) J Biol Chem , vol.274 , pp. 24947-24952
    • Mueller, S.C.1    Ghersi, G.2    Akiyama, S.K.3    Sang, Q.X.4    Howard, L.5
  • 15
    • 0036799301 scopus 로고    scopus 로고
    • Molecular proximity of seprase and the urokinase-type plasminogen activator receptor on malignant melanoma cell membranes: Dependence on beta1 integrins and the cytoskeleton
    • Artym VV, Kindzelskii AL, Chen WT, Petty HR (2002) Molecular proximity of seprase and the urokinase-type plasminogen activator receptor on malignant melanoma cell membranes: dependence on beta1 integrins and the cytoskeleton. Carcinogenesis 23: 1593-1601.
    • (2002) Carcinogenesis , vol.23 , pp. 1593-1601
    • Artym, V.V.1    Kindzelskii, A.L.2    Chen, W.T.3    Petty, H.R.4
  • 16
    • 0028152543 scopus 로고
    • A potential marker protease of invasiveness, seprase, is localized on invadopodia of human malignant melanoma cells
    • Monsky WL, Lin CY, Aoyama A, Kelly T, Akiyama SK, et al. (1994) A potential marker protease of invasiveness, seprase, is localized on invadopodia of human malignant melanoma cells. Cancer Res 54: 5702-5710. (Pubitemid 24346270)
    • (1994) Cancer Research , vol.54 , Issue.21 , pp. 5702-5710
    • Monsky, W.L.1    Lin, C.-Y.2    Aoyama, A.3    Kelly, T.4    Akiyama, S.K.5    Mueller, S.C.6    Chen, W.-T.7
  • 17
    • 79958250916 scopus 로고    scopus 로고
    • FAP-overexpressing fibroblasts produce an extracellular matrix that enhances invasive velocity and directionality of pancreatic cancer cells
    • Lee HO, Mullins SR, Franco-Barraza J, Valianou M, Cukierman E, et al. (2011) FAP-overexpressing fibroblasts produce an extracellular matrix that enhances invasive velocity and directionality of pancreatic cancer cells. BMC Cancer 11: 245.
    • (2011) BMC Cancer , vol.11 , pp. 245
    • Lee, H.O.1    Mullins, S.R.2    Franco-Barraza, J.3    Valianou, M.4    Cukierman, E.5
  • 18
    • 48749103523 scopus 로고    scopus 로고
    • Fibroblast activation protein alpha identifies mesenchymal stromal cells from human bone marrow
    • Bae S, Park CW, Son HK, Ju HK, Paik D, et al. (2008) Fibroblast activation protein alpha identifies mesenchymal stromal cells from human bone marrow. Br J Haematol 142: 827-830.
    • (2008) Br J Haematol , vol.142 , pp. 827-830
    • Bae, S.1    Park, C.W.2    Son, H.K.3    Ju, H.K.4    Paik, D.5
  • 19
    • 84880656055 scopus 로고    scopus 로고
    • Immune targeting of fibroblast activation protein triggers recognition of multipotent bone marrow stromal cells and cachexia
    • Tran E, Chinnasamy D, Yu Z, Morgan RA, Lee CC, et al. (2013) Immune targeting of fibroblast activation protein triggers recognition of multipotent bone marrow stromal cells and cachexia. J Exp Med 210: 1125-1135.
    • (2013) J Exp Med , vol.210 , pp. 1125-1135
    • Tran, E.1    Chinnasamy, D.2    Yu, Z.3    Morgan, R.A.4    Lee, C.C.5
  • 21
    • 36348977575 scopus 로고    scopus 로고
    • Immunomodulatory properties of mesenchymal stromal cells
    • DOI 10.1182/blood-2007-02-069716
    • Nauta AJ, Fibbe WE (2007) Immunomodulatory properties of mesenchymal stromal cells. Blood 110: 3499-3506. (Pubitemid 350159613)
    • (2007) Blood , vol.110 , Issue.10 , pp. 3499-3506
    • Nauta, A.J.1    Fibbe, W.E.2
  • 22
    • 0036142213 scopus 로고    scopus 로고
    • Human mesenchymal stem cells differentiate to a cardiomyocyte phenotype in the adult murine heart
    • DOI 10.1161/hc0102.101442
    • Toma C, Pittenger MF, Cahill KS, Byrne BJ, Kessler PD (2002) Human mesenchymal stem cells differentiate to a cardiomyocyte phenotype in the adult murine heart. Circulation 105: 93-98. (Pubitemid 34049148)
    • (2002) Circulation , vol.105 , Issue.1 , pp. 93-98
    • Toma, C.1    Pittenger, M.F.2    Cahill, K.S.3    Byrne, B.J.4    Kessler, P.D.5
  • 23
    • 42149189474 scopus 로고    scopus 로고
    • Mesenchymal stem cells are recruited into wounded skin and contribute to wound repair by transdifferentiation into multiple skin cell type
    • Sasaki M, Abe R, Fujita Y, Ando S, Inokuma D, et al. (2008) Mesenchymal stem cells are recruited into wounded skin and contribute to wound repair by transdifferentiation into multiple skin cell type. J Immunol 180: 2581-2587.
    • (2008) J Immunol , vol.180 , pp. 2581-2587
    • Sasaki, M.1    Abe, R.2    Fujita, Y.3    Ando, S.4    Inokuma, D.5
  • 27
    • 65649088506 scopus 로고    scopus 로고
    • Biochemical properties and expression profile of human prolyl dipeptidase DPP9
    • Tang HK, Tang HY, Hsu SC, Chu YR, Chien CH, et al. (2009) Biochemical properties and expression profile of human prolyl dipeptidase DPP9. Arch Biochem Biophys 485: 120-127.
    • (2009) Arch Biochem Biophys , vol.485 , pp. 120-127
    • Tang, H.K.1    Tang, H.Y.2    Hsu, S.C.3    Chu, Y.R.4    Chien, C.H.5
  • 28
    • 84877836310 scopus 로고    scopus 로고
    • Mesenchymal stem cells tune the development of monocyte-derived dendritic cells toward a myeloid-derived suppressive phenotype through growth-regulated oncogene chemokines
    • Chen HW, Chen HY, Wang LT, Wang FH, Fang LW, et al. (2013) Mesenchymal stem cells tune the development of monocyte-derived dendritic cells toward a myeloid-derived suppressive phenotype through growth-regulated oncogene chemokines. J Immunol 190: 5065-5077.
    • (2013) J Immunol , vol.190 , pp. 5065-5077
    • Chen, H.W.1    Chen, H.Y.2    Wang, L.T.3    Wang, F.H.4    Fang, L.W.5
  • 29
    • 18744406691 scopus 로고    scopus 로고
    • Induction and detection of human mesenchymal stem cell migration in the 48-well reusable transwell assay
    • DOI 10.1089/scd.2005.14.231
    • Ruster B, Grace B, Seitz O, Seifried E, Henschler R (2005) Induction and detection of human mesenchymal stem cell migration in the 48-well reusable transwell assay. Stem Cells Dev 14: 231-235. (Pubitemid 40677396)
    • (2005) Stem Cells and Development , vol.14 , Issue.2 , pp. 231-235
    • Ruster, B.1    Grace, B.2    Seitz, O.3    Seifried, E.4    Henschler, R.5
  • 30
    • 77956717491 scopus 로고    scopus 로고
    • Substituted 4-carboxymethylpyroglutamic acid diamides as potent and selective inhibitors of fibroblast activation protein
    • Tsai TY, Yeh TK, Chen X, Hsu T, Jao YC, et al. (2010) Substituted 4-carboxymethylpyroglutamic acid diamides as potent and selective inhibitors of fibroblast activation protein. J Med Chem 53: 6572-6583.
    • (2010) J Med Chem , vol.53 , pp. 6572-6583
    • Tsai, T.Y.1    Yeh, T.K.2    Chen, X.3    Hsu, T.4    Jao, Y.C.5
  • 31
    • 84877690891 scopus 로고    scopus 로고
    • Identification of selective and potent inhibitors of fibroblast activation protein and prolyl oligopeptidase
    • Poplawski SE, Lai JH, Li Y, Jin Z, Liu Y, et al. (2013) Identification of selective and potent inhibitors of fibroblast activation protein and prolyl oligopeptidase. J Med Chem 56: 3467-3477.
    • (2013) J Med Chem , vol.56 , pp. 3467-3477
    • Poplawski, S.E.1    Lai, J.H.2    Li, Y.3    Jin, Z.4    Liu, Y.5
  • 32
    • 10044284340 scopus 로고    scopus 로고
    • Brk activates Rac1 and promotes cell migration and invasion by phosphorylating paxillin
    • DOI 10.1128/MCB.24.24.10558-10572.2004
    • Chen HY, Shen CH, Tsai YT, Lin FC, Huang YP, et al. (2004) Brk activates rac1 and promotes cell migration and invasion by phosphorylating paxillin. Mol Cell Biol 24: 10558-10572. (Pubitemid 39603116)
    • (2004) Molecular and Cellular Biology , vol.24 , Issue.24 , pp. 10558-10572
    • Chen, H.-Y.1    Shen, C.-H.2    Tsai, Y.-T.3    Lin, F.-C.4    Huang, Y.-P.5    Chen, R.-H.6
  • 33
    • 23744458987 scopus 로고    scopus 로고
    • Characterization of cancer stroma markers: In silico analysis of an mRNA expression database for fibroblast activation protein and endosialin
    • Dolznig H, Schweifer N, Puri C, Kraut N, Rettig WJ, et al. (2005) Characterization of cancer stroma markers: in silico analysis of an mRNA expression database for fibroblast activation protein and endosialin. Cancer Immun 5: 10.
    • (2005) Cancer Immun , vol.5 , pp. 10
    • Dolznig, H.1    Schweifer, N.2    Puri, C.3    Kraut, N.4    Rettig, W.J.5
  • 34
    • 0033579444 scopus 로고    scopus 로고
    • Fibroblast activation protein, a dual specificity serine protease expressed in reactive human tumor stromal fibroblasts
    • Park JE, Lenter MC, Zimmermann RN, Garin-Chesa P, Old LJ, et al. (1999) Fibroblast activation protein, a dual specificity serine protease expressed in reactive human tumor stromal fibroblasts. J Biol Chem 274: 36505-36512.
    • (1999) J Biol Chem , vol.274 , pp. 36505-36512
    • Park, J.E.1    Lenter, M.C.2    Zimmermann, R.N.3    Garin-Chesa, P.4    Old, L.J.5
  • 35
    • 62449127652 scopus 로고    scopus 로고
    • Migration of bone marrow-derived mesenchymal stem cells induced by tumor necrosis factor-alpha and its possible role in wound healing
    • Fu X, Han B, Cai S, Lei Y, Sun T, et al. (2009) Migration of bone marrow-derived mesenchymal stem cells induced by tumor necrosis factor-alpha and its possible role in wound healing. Wound Repair Regen 17: 185-191.
    • (2009) Wound Repair Regen , vol.17 , pp. 185-191
    • Fu, X.1    Han, B.2    Cai, S.3    Lei, Y.4    Sun, T.5
  • 36
    • 78149413180 scopus 로고    scopus 로고
    • Interleukin 6 mediated recruitment of mesenchymal stem cells to the hypoxic tumor milieu
    • Rattigan Y, Hsu JM, Mishra PJ, Glod J, Banerjee D (2010) Interleukin 6 mediated recruitment of mesenchymal stem cells to the hypoxic tumor milieu. Exp Cell Res 316: 3417-3424.
    • (2010) Exp Cell Res , vol.316 , pp. 3417-3424
    • Rattigan, Y.1    Hsu, J.M.2    Mishra, P.J.3    Glod, J.4    Banerjee, D.5
  • 38
    • 0032559362 scopus 로고    scopus 로고
    • Rho GTPases and the actin cytoskeleton
    • Hall A (1998) Rho GTPases and the actin cytoskeleton. Science 279: 509-514.
    • (1998) Science , vol.279 , pp. 509-514
    • Hall, A.1
  • 39
    • 67650538040 scopus 로고    scopus 로고
    • Transforming growth factor-beta promotes recruitment of bone marrow cells and bone marrow-derived mesenchymal stem cells through stimulation of MCP-1 production in vascular smooth muscle cells
    • Zhang F, Tsai S, Kato K, Yamanouchi D, Wang C, et al. (2009) Transforming growth factor-beta promotes recruitment of bone marrow cells and bone marrow-derived mesenchymal stem cells through stimulation of MCP-1 production in vascular smooth muscle cells. J Biol Chem 284: 17564-17574.
    • (2009) J Biol Chem , vol.284 , pp. 17564-17574
    • Zhang, F.1    Tsai, S.2    Kato, K.3    Yamanouchi, D.4    Wang, C.5
  • 40
    • 1542274482 scopus 로고    scopus 로고
    • Cytokines and Wound Healing: The Role of Cytokine and Anticytokine Therapy in the Repair Response
    • DOI 10.1097/01.BCR.0000111766.97335.34
    • Efron PA, Moldawer LL (2004) Cytokines and wound healing: the role of cytokine and anticytokine therapy in the repair response. J Burn Care Rehabil 25: 149-160. (Pubitemid 38296037)
    • (2004) Journal of Burn Care and Rehabilitation , vol.25 , Issue.2 , pp. 149-160
    • Efron, P.A.1    Moldawer, L.L.2
  • 41
    • 34547217039 scopus 로고    scopus 로고
    • The in vitro migration capacity of human bone marrow mesenchymal stem cells: Comparison of chemokine and growth factor chemotactic activities
    • DOI 10.1634/stemcells.2007-0054
    • Ponte AL, Marais E, Gallay N, Langonne A, Delorme B, et al. (2007) The in vitro migration capacity of human bone marrow mesenchymal stem cells: comparison of chemokine and growth factor chemotactic activities. Stem Cells 25: 1737-1745. (Pubitemid 47121852)
    • (2007) Stem Cells , vol.25 , Issue.7 , pp. 1737-1745
    • Ponte, A.L.1    Marais, E.2    Gallay, N.3    Langonne, A.4    Delorme, B.5    Herault, O.6    Charbord, P.7    Domenech, J.8
  • 44
    • 34249290744 scopus 로고    scopus 로고
    • Recent advances into the understanding of mesenchymal stem cell trafficking
    • DOI 10.1111/j.1365-2141.2007.06610.x
    • Fox JM, Chamberlain G, Ashton BA, Middleton J (2007) Recent advances into the understanding of mesenchymal stem cell trafficking. Br J Haematol 137: 491-502. (Pubitemid 46817339)
    • (2007) British Journal of Haematology , vol.137 , Issue.6 , pp. 491-502
    • Fox, J.M.1    Chamberlain, G.2    Ashton, B.A.3    Middleton, J.4
  • 45
    • 34247368028 scopus 로고    scopus 로고
    • MMP-2, MT1-MMP, and TIMP-2 are essential for the invasive capacity of human mesenchymal stem cells: Differential regulation by inflammatory cytokines
    • DOI 10.1182/blood-2006-10-051060
    • Ries C, Egea V, Karow M, Kolb H, Jochum M, et al. (2007) MMP-2, MT1-MMP, and TIMP-2 are essential for the invasive capacity of human mesenchymal stem cells: differential regulation by inflammatory cytokines. Blood 109: 4055-4063. (Pubitemid 46641761)
    • (2007) Blood , vol.109 , Issue.9 , pp. 4055-4063
    • Ries, C.1    Egea, V.2    Karow, M.3    Kolb, H.4    Jochum, M.5    Neth, P.6
  • 46
    • 0037069690 scopus 로고    scopus 로고
    • Rho GTPases in cell biology
    • DOI 10.1038/nature01148
    • Etienne-Manneville S, Hall A (2002) Rho GTPases in cell biology. Nature 420: 629-635. (Pubitemid 36764489)
    • (2002) Nature , vol.420 , Issue.6916 , pp. 629-635
    • Etienne-Manneville, S.1    Hall, A.2
  • 48
    • 0035152391 scopus 로고    scopus 로고
    • Integrin-mediated adhesion regulates cell polarity and membrane protrusion through the Rho family of GTPases
    • Cox EA, Sastry SK, Huttenlocher A (2001) Integrin-mediated adhesion regulates cell polarity and membrane protrusion through the Rho family of GTPases. Mol Biol Cell 12: 265-277. (Pubitemid 33051574)
    • (2001) Molecular Biology of the Cell , vol.12 , Issue.2 , pp. 265-277
    • Cox, E.A.1    Sastry, S.K.2    Huttenlocher, A.3
  • 49
  • 50
    • 0032991828 scopus 로고    scopus 로고
    • Rho-kinase in human neutrophils: A role in signalling for myosin light chain phosphorylation and cell migration
    • Niggli V (1999) Rho-kinase in human neutrophils: a role in signalling for myosin light chain phosphorylation and cell migration. FEBS Lett 445: 69-72.
    • (1999) FEBS Lett , vol.445 , pp. 69-72
    • Niggli, V.1
  • 51
    • 0035869651 scopus 로고    scopus 로고
    • The RHO/RHO-kinase and the phosphatidylinositol 3-kinase pathways are essential for spontaneous locomotion of Walker 256 carcinosarcoma cells
    • DOI 10.1002/1097-0215(200102)9999:9999<::AID-IJC11
    • Wicki A, Niggli V (2001) The Rho/Rho-kinase and the phosphatidylinositol 3-kinase pathways are essential for spontaneous locomotion of Walker 256 carcinosarcoma cells. Int J Cancer 91: 763-771. (Pubitemid 32178642)
    • (2001) International Journal of Cancer , vol.91 , Issue.6 , pp. 763-771
    • Wicki, A.1    Niggli, V.2
  • 54
    • 79960898998 scopus 로고    scopus 로고
    • Fibroblast activation protein-alpha promotes tumor growth and invasion of breast cancer cells through non-enzymatic functions
    • Huang Y, Simms AE, Mazur A, Wang S, Leon NR, et al. (2011) Fibroblast activation protein-alpha promotes tumor growth and invasion of breast cancer cells through non-enzymatic functions. Clin Exp Metastasis 28: 567-579.
    • (2011) Clin Exp Metastasis , vol.28 , pp. 567-579
    • Huang, Y.1    Simms, A.E.2    Mazur, A.3    Wang, S.4    Leon, N.R.5
  • 55
    • 0842281652 scopus 로고    scopus 로고
    • Rho and Rac Take Center Stage
    • DOI 10.1016/S0092-8674(04)00003-0
    • Burridge K, Wennerberg K (2004) Rho and Rac take center stage. Cell 116: 167-179. (Pubitemid 38167310)
    • (2004) Cell , vol.116 , Issue.2 , pp. 167-179
    • Burridge, K.1    Wennerberg, K.2
  • 56
    • 0033615966 scopus 로고    scopus 로고
    • Rac downregulates Rho activity: Reciprocal balance between both GTPases determines cellular morphology and migratory behavior
    • Sander EE, ten Klooster JP, van Delft S, van der Kammen RA, Collard JG (1999) Rac downregulates Rho activity: reciprocal balance between both GTPases determines cellular morphology and migratory behavior. J Cell Biol 147: 1009-1022.
    • (1999) J Cell Biol , vol.147 , pp. 1009-1022
    • Sander, E.E.1    Ten Klooster, J.P.2    Van Delft, S.3    Van Der Kammen, R.A.4    Collard, J.G.5
  • 57
    • 84863051239 scopus 로고    scopus 로고
    • Integrin alpha6beta4 cooperates with LPA signaling to stimulate Rac through AKAP-Lbc-mediated RhoA activation
    • O'Connor KL, Chen M, Towers LN (2012) Integrin alpha6beta4 cooperates with LPA signaling to stimulate Rac through AKAP-Lbc-mediated RhoA activation. Am J Physiol Cell Physiol 302: C605-614.
    • (2012) Am J Physiol Cell Physiol , vol.302
    • O'Connor, K.L.1    Chen, M.2    Towers, L.N.3
  • 58
    • 20444421293 scopus 로고    scopus 로고
    • Fibroblast activation protein-alpha and dipeptidyl peptidase IV (CD26): Cell-surface proteases that activate cell signaling and are potential targets for cancer therapy
    • Kelly T (2005) Fibroblast activation protein-alpha and dipeptidyl peptidase IV (CD26): cell-surface proteases that activate cell signaling and are potential targets for cancer therapy. Drug Resist Updat 8: 51-58.
    • (2005) Drug Resist Updat , vol.8 , pp. 51-58
    • Kelly, T.1
  • 60
    • 66849101632 scopus 로고    scopus 로고
    • Adhesion signaling - crosstalk between integrins, Src and Rho
    • Huveneers S, Danen EH (2009) Adhesion signaling - crosstalk between integrins, Src and Rho. J Cell Sci 122: 1059-1069.
    • (2009) J Cell Sci , vol.122 , pp. 1059-1069
    • Huveneers, S.1    Danen, E.H.2
  • 61
    • 0035158177 scopus 로고    scopus 로고
    • RhoA-dependent switch between alpha2beta1 and alpha3beta1 integrins is induced by laminin-5 during early stage of HT-29 cell differentiation
    • Gout SP, Jacquier-Sarlin MR, Rouard-Talbot L, Rousselle P, Block MR (2001) RhoA-dependent switch between alpha2beta1 and alpha3beta1 integrins is induced by laminin-5 during early stage of HT-29 cell differentiation. Mol Biol Cell 12: 3268-3281. (Pubitemid 33062978)
    • (2001) Molecular Biology of the Cell , vol.12 , Issue.10 , pp. 3268-3281
    • Gout, S.P.1    Jacquier-Sarlin, M.R.2    Rouard-Talbot, L.3    Rousselle, P.4    Block, M.R.5
  • 62
    • 0345643514 scopus 로고    scopus 로고
    • Regulation of matrix metalloproteinase expression in tumor invasion
    • Westermarck J, Kahari VM (1999) Regulation of matrix metalloproteinase expression in tumor invasion. FASEB J 13: 781-792. (Pubitemid 29220691)
    • (1999) FASEB Journal , vol.13 , Issue.8 , pp. 781-792
    • Westermarck, J.1    Kahari, V.-M.2
  • 63
    • 0025866180 scopus 로고
    • Transcriptional and post-transcriptional regulation of 72-kDa gelatinase/type IV collagenase by transforming growth factor-beta1 in human fibroblasts: Comparisons with collagenase and tissue inhibitor of matrix metalloproteinase gene expression
    • Overall CM, Wrana JL, Sodek J (1991) Transcriptional and post-transcriptional regulation of 72-kDa gelatinase/type IV collagenase by transforming growth factor-beta 1 in human fibroblasts. Comparisons with collagenase and tissue inhibitor of matrix metalloproteinase gene expression. J Biol Chem 266: 14064-14071. (Pubitemid 21907461)
    • (1991) Journal of Biological Chemistry , vol.266 , Issue.21 , pp. 14064-14071
    • Overall, C.M.1    Wrana, J.L.2    Sodek, J.3
  • 64
    • 0028338449 scopus 로고
    • Regulation of 92-kD gelatinase release in HL-60 leukemia cells: Tumor necrosis factor-alpha as an autocrine stimulus for basal- and phorbol ester-induced secretion
    • Ries C, Kolb H, Petrides PE (1994) Regulation of 92-kD gelatinase release in HL-60 leukemia cells: tumor necrosis factor-alpha as an autocrine stimulus for basal- and phorbol ester-induced secretion. Blood 83: 3638-3646.
    • (1994) Blood , vol.83 , pp. 3638-3646
    • Ries, C.1    Kolb, H.2    Petrides, P.E.3
  • 65
    • 0029310597 scopus 로고
    • Cytokine regulation of matrix metalloproteinase activity and its regulatory dysfunction in disease
    • Ries C, Petrides PE (1995) Cytokine regulation of matrix metalloproteinase activity and its regulatory dysfunction in disease. Biol Chem Hoppe Seyler 376: 345-355.
    • (1995) Biol Chem Hoppe Seyler , vol.376 , pp. 345-355
    • Ries, C.1    Petrides, P.E.2
  • 66
    • 70350746065 scopus 로고    scopus 로고
    • TGF-beta induces fibroblast activation protein expression; fibroblast activation protein expression increases the proliferation, adhesion, and migration of HO-8910PM
    • [corrected]
    • Chen H, Yang WW, Wen QT, Xu L, Chen M (2009) TGF-beta induces fibroblast activation protein expression; fibroblast activation protein expression increases the proliferation, adhesion, and migration of HO-8910PM [corrected]. Exp Mol Pathol 87: 189-194.
    • (2009) Exp Mol Pathol , vol.87 , pp. 189-194
    • Chen, H.1    Yang, W.W.2    Wen, Q.T.3    Xu, L.4    Chen, M.5


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