Systemic polyethylene glycol-modified (PEGylated) superoxide dismutase and catalase mixture attenuates radiation pulmonary fibrosis in the C57/bl6 mouse

Radiotherapy and Oncology

Volumn 81, Issue 2, 2006, Pages 196-205

  Machtay, Mitchell ^a,b,d   Scherpereel, Arnaud ^a,b   Santiago, José ^a,b   Lee, James ^a,b   McDonough, Jim ^a,b   Kinniry, Paul ^a,b   Arguiri, Evguenia ^a,b   Shuvaev, Vladimir V ^a,b   Sun, Jing ^a,b   Cengel, Keith ^a,b   Solomides, Charalambos C ^b,c   Christofidou Solomidou, Melpo ^a,b  

^a Pulmonary Allergy and Critical Care Division ^*  (United States)

^b HOSPITAL OF THE UNIVERSITY OF PENNSYLVANIA   (United States)

^c TEMPLE UNIVERSITY HOSPITAL   (United States)

^d THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

Antioxidant enzymes; Apoptosis; Catalase; Inflammation; Lung fibrosis; PEG; Radiation pneumonopathy; Superoxide dismutase; TGF ; Thoracic radiation

Indexed keywords

ANTIOXIDANT; HYDROXYPROLINE; PEGYLATED CATALASE; PEGYLATED SUPEROXIDE DISMUTASE; PROTEIN BAX; PROTEIN P21; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CANCER PREVENTION; CONTROLLED STUDY; FEMALE; INFLAMMATION; INTERSTITIAL PNEUMONIA; IRRADIATION; LEWIS CARCINOMA; LUNG; LUNG FIBROSIS; LUNG INJURY; MOUSE; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; RADIATION INJURY; THORAX; TREATMENT RESPONSE;

ANIMALS; BCL-2-ASSOCIATED X PROTEIN; BIOLOGICAL MARKERS; CATALASE; DRUG COMBINATIONS; FEMALE; LUNG; LUNG NEOPLASMS; MICE; MICE, INBRED C57BL; POLYETHYLENE GLYCOLS; PROTEIN-SERINE-THREONINE KINASES; PULMONARY FIBROSIS; RADIATION PNEUMONITIS; RADIATION-PROTECTIVE AGENTS; RNA, MESSENGER; SUPEROXIDE DISMUTASE; THORAX; TRANSFORMING GROWTH FACTOR BETA1; X-RAYS;

EID: 33751214559     PISSN: 01678140     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.radonc.2006.09.013     Document Type: Article

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