Endocytic collagen degradation: A novel mechanism involved in protection against liver fibrosis

Journal of Pathology

Volumn 227, Issue 1, 2012, Pages 94-105

  Madsen, Daniel H ^a   Jürgensen, Henrik J ^a   Ingvarsen, Signe ^a,b   Melander, Maria C ^a   Vainer, Ben ^c   Egerod, Kristoffer L ^b   Hald, Andreas ^b   Rønø, Birgitte ^b   Madsen, Charlotte A ^a   Bugge, Thomas H ^d   Engelholm, Lars H ^a   Behrendt, Niels ^a  

^a FINSEN LABORATORY   (Denmark)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

^c Rigshospitalet   (Denmark)

^d NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

Endo180; Endocytosis; HSC; Knockout mouse; Liver disease model; Mannose receptor; Matrix metalloproteinase; Matrix remodelling; MRC2; uPARAP

Indexed keywords

COLLAGEN; COLLAGEN RECEPTOR; GLYCOPROTEIN; PROTEIN ENDO180; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COLLAGEN DEGRADATION; CONTROLLED STUDY; ENDOCYTOSIS; FEMALE; HUMAN; HUMAN TISSUE; LIVER FIBROSIS; LIVER PROTECTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR INTRINSIC ACTIVITY; UPREGULATION;

ANIMALS; ANTIBODIES, BLOCKING; CELL LINE; COLLAGEN; ENDOCYTOSIS; FEMALE; FIBROBLASTS; HEPATIC STELLATE CELLS; HUMANS; LIVER CIRRHOSIS, EXPERIMENTAL; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED STRAINS; MICE, KNOCKOUT; RECEPTORS, CELL SURFACE; UP-REGULATION;

EID: 84859631506     PISSN: 00223417     EISSN: 10969896     Source Type: Journal    
DOI: 10.1002/path.3981     Document Type: Article

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